2014 Journal Article Optimization of transcription factor binding map accuracy utilizing knockout-mouse modelsKrebs, Wolfgang, Schmidt, Susanne V., Goren, Alon, De Nardo, Dominic, Labzin, Larisa, Bovier, Anton, Ulas, Thomas, Theis, Heidi, Kraut, Michael, Latz, Eicke, Beyer, Marc and Schultze, Joachim L. (2014). Optimization of transcription factor binding map accuracy utilizing knockout-mouse models. Nucleic Acids Research, 42 (21), 13051-13060. doi: 10.1093/nar/gku1078 |
2014 Journal Article Transcriptome-based network analysis reveals a spectrum model of human macrophage activationXue, Jia, Schmidt, Susanne V., Sander, Jil, Draffehn, Astrid, Krebs, Wolfgang, Quester, Inga, DeNardo, Dominic, Gohel, Trupti D., Emde, Martina, Schmidleithner, Lisa, Ganesan, Hariharasudan, Nino-Castro, Andrea, Mallmann, Michael R., Labzin, Larisa, Theis, Heidi, Kraut, Michael, Beyer, Marc, Latz, Eicke, Freeman, Tom C., Ulas, Thomas and Schultze, Joachim L. (2014). Transcriptome-based network analysis reveals a spectrum model of human macrophage activation. Immunity, 40 (2), 274-288. doi: 10.1016/j.immuni.2014.01.006 |
2014 Journal Article High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3De Nardo, Dominic, Labzin, Larisa I., Kono, Hajime, Seki, Reiko, Schmidt, Susanne V., Beyer, Marc, Xu, Dakang, Zimmer, Sebastian, Lahrmann, Catharina, Schildberg, Frank A., Vogelhuber, Johanna, Kraut, Michael, Ulas, Thomas, Kerksiek, Anja, Krebs, Wolfgang, Bode, Niklas, Grebe, Alena, Fitzgerald, Michael L., Hernandez, Nicholas J., Williams, Bryan R.G., Knolle, Percy, Kneilling, Manfred, Röcken, Martin, Lütjohann, Dieter, Wright, Samuel D., Schultze, Joachim L. and Latz, Eicke (2014). High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3. Nature Immunology, 15 (2), 152-160. doi: 10.1038/ni.2784 |
2014 Journal Article Cutting edge: the UNC93B1 tyrosine-based motif regulates trafficking and TLR responses via separate mechanismsPelka, Karin, Phulphagar, Kshiti, Zimmermann, Jana, Stahl, Rainer, Schmid-Burgk, Jonathan L., Schmidt, Tobias, Spille, Jan-Hendrik, Labzin, Larisa I., Agrawal, Sudhir, Kandimalla, Ekambar R., Casanova, Jean-Laurent, Hornung, Veit, Marshak-Rothstein, Ann, Höning, Stefan and Latz, Eicke (2014). Cutting edge: the UNC93B1 tyrosine-based motif regulates trafficking and TLR responses via separate mechanisms. Journal of Immunology, 193 (7), 3257-3261. doi: 10.4049/jimmunol.1301886 |
2013 Journal Article Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophagesShakespear, Melanie R., Hohenhaus, Daniel M., Kelly, Greg M., Kamal, Nabilah A., Gupta, Praveer, Labzin, Larisa I., Schroder, Kate, Garceau, Valerie, Barbero, Sheila, Iyer, Abishek, Hume, David A., Reid, Robert C., Irvine, Katharine M., Fairlie, David P. and Sweet, Matthew J. (2013). Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophages. Journal of Biological Chemistry, 288 (35), 25362-25374. doi: 10.1074/jbc.M113.496281 |
2012 Journal Article Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophagesSchroder, Kate, Irvine, Katharine M., Taylor, Martin S., Bokil, Nilesh J., Le Cao, Kim-Anh, Masterman, Kelly-Anne, Labzin, Larisa I., Semple, Colin A., Kapetanovic, Ronan, Fairbairn, Lynsey, Akalin, Altuna, Faulkner, Geoffrey J., Baillie, John Kenneth, Gongora, Milena, Daub, Carsten O., Kawaji, Hideya, McLachlan, Geoffrey J., Goldman, Nick, Grimmond, Sean M., Carninci, Piero, Suzuki, Harukazu, Hayashizaki, Yoshihide, Lenhard, Boris, Hume, David A. and Sweet, Matthew J. (2012). Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages. Proceedings of the National Academy of Sciences of the USA, 109 (16), E944-E953. doi: 10.1073/pnas.1110156109 |
2010 Journal Article Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D-2 synthasesChrist, Angelika N., Labzin, Larisa, Bourne, Gregory T., Fukunishi, Hirotada, Weber, Jane E., Sweet, Matthew J., Smythe, Mark L. and Flanagan, Jack U. (2010). Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D-2 synthases. Journal of Medicinal Chemistry, 53 (15), 5536-5548. doi: 10.1021/jm100194a |
2010 Journal Article Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPSHalili, Maria A., Andrews, Melanie R., Labzin, Larisa I., Schroder, Kate, Matthias, Gabriele, Cao, Chun, Lovelace, Erica, Reid, Robert C., Le, Giang T., Hume, David A., Irvine, Katharine M., Matthias, Patrick, Fairlie, David P. and Sweet, Matthew J. (2010). Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS. Journal of Leukocyte Biology, 87 (6), 1103-1114. doi: 10.1189/jlb.0509363 |