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2017

Conference Publication

Durable Improvement in Clinical Outcomes in Patients With Relapsing-Remitting Multiple Sclerosis Who Discontinued SC IFNB-1a and Initiated Alemtuzumab: CARE-MS I Extension Study 4-Year Follow-up

Oreja-Guevara, Celia, Alroughani, Raed, Brassat, David, Boyko, Alexey N., McCombe, Pamela, Steingo, Brian, Van Wijmeersch, Bart, Margolin, David H., Thangavelu, Karthinathan, Rodriguez, Claudio E., Vermersch, Patrick and on behalf of the CARE-MS I and CAMMS03409 Investigators (2017). Durable Improvement in Clinical Outcomes in Patients With Relapsing-Remitting Multiple Sclerosis Who Discontinued SC IFNB-1a and Initiated Alemtuzumab: CARE-MS I Extension Study 4-Year Follow-up. AAN 69th Annual Meeting, Boston, MA United States, 22-28 April 2017. Philadelphia, PA United States: Wolters Kluwer. doi: 10.1212/wnl.88.16_supplement.p5.360

Durable Improvement in Clinical Outcomes in Patients With Relapsing-Remitting Multiple Sclerosis Who Discontinued SC IFNB-1a and Initiated Alemtuzumab: CARE-MS I Extension Study 4-Year Follow-up

2017

Conference Publication

Pregnancy outcomes in patients with RRMS treated with alemtuzumab from the clinical development program

Rog, D., Oh, J., Chambers, C., Hellwig, K., McCombe, P., Otero, S., Margolin, D. H., Daizadeh, N. and Compston, D. A. S. (2017). Pregnancy outcomes in patients with RRMS treated with alemtuzumab from the clinical development program. 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517731404

Pregnancy outcomes in patients with RRMS treated with alemtuzumab from the clinical development program

2017

Conference Publication

Comparison of Faecal Microbe Diversity Between Motor Neurone Disease (Mnd) and Control Participants

Steyn, Frederik J., Restuadi, Restuadi, Ioannides, Zara, Ngo, Shyuan T., McRae, Allan, Wray, Naomi R., Henderson, Robert and McCombe, Pamela (2017). Comparison of Faecal Microbe Diversity Between Motor Neurone Disease (Mnd) and Control Participants. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, Australia, 9-12 May 2017. London, United Kingdom: BMJ. doi: 10.1136/jnnp-2017-316074.81

Comparison of Faecal Microbe Diversity Between Motor Neurone Disease (Mnd) and Control Participants

2017

Conference Publication

Timing of high-efficacy disease modifying therapies for relapsing-remitting multiple sclerosis

Merkel, B., Jokubaitis, V., Spelman, T., Horakova, D., Havrdova, E., Trojano, M., Izquierdo, G., Lugaresi, A., Prat, A., Girard, M., Duquette, P., Sola, P., Ferraro, D., Grammond, P., Hupperts, R., Bergamaschi, R., Alroughani, R., Boz, C., Terzi, M., Pucci, E., Van Pesch, V., Grand'Maison, F., Fernandez-Bolanos, R., Lechner-Scott, J., Spitaleri, D., Shaygannejad, V., Iuliano, G., Granella, F., Solaro, C. ... Kalincik, T. (2017). Timing of high-efficacy disease modifying therapies for relapsing-remitting multiple sclerosis. 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517731283

Timing of high-efficacy disease modifying therapies for relapsing-remitting multiple sclerosis

2017

Conference Publication

Timing of High-Efficacy Disease Modifying Therapies for Relapsing-Remitting Multiple Sclerosis

Merkel, Bernd, Jokubaitis, Vilija, Spelman, Tim, Lechner-Scott, Jeannette, McCombe, Pamela, Slee, Mark, Vucic, Steve, Skibina, Olga, Barnett, Michael, Hodgkinson, Suzanne, Butzkueven, Helmut and Kalincik, Tomas (2017). Timing of High-Efficacy Disease Modifying Therapies for Relapsing-Remitting Multiple Sclerosis. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, Australia, May 09-12, 2017. LONDON: BMJ PUBLISHING GROUP. doi: 10.1136/jnnp-2017-316074.16

Timing of High-Efficacy Disease Modifying Therapies for Relapsing-Remitting Multiple Sclerosis

2017

Conference Publication

Pregnancy incidence and therapy exposure in relapsing forms of MS: a 12-year retrospective multicentre analysis

Jokubaitis, V. G., Havrdova, E., Horakova, D., Izquierdo, G., Kalincik, T., van der Walt, A., Nguyen, A. -L., Terzi, M., Alroughani, R., Duquette, P., Girard, M., Prat, A., Boz, C., Sola, P., Lugaresi, A., Lechner-Scott, J., Barnett, M., Grand'Maison, F., Grammond, P., Ramo, C., Turkoglu, R., McCombe, P., Hupperts, R., Bolanos, R. Fernandez, Pucci, E., Trojano, M., Granella, F., Spitaleri, D., Van Pesch, V. ... Butzkueven, H. (2017). Pregnancy incidence and therapy exposure in relapsing forms of MS: a 12-year retrospective multicentre analysis. 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517731404

Pregnancy incidence and therapy exposure in relapsing forms of MS: a 12-year retrospective multicentre analysis

2017

Conference Publication

Persistence to fingolimod compared with other disease modifying therapies in the Australian real-world setting using the MS base registry

Spelman, T., Schulz, M., Arora, B., Chung, E., Juneja, P., Walker, R., Verhaeghe, S., Butzkueven, H., Hodgkinson, S., Lechner-Scott, J., McCombe, P., Slee, M., Butler, E., Barnett, M., Skibina, O., Vucic, S., Macdonell, R., Shuey, N., Taylor, B. and Broadley, S. (2017). Persistence to fingolimod compared with other disease modifying therapies in the Australian real-world setting using the MS base registry. 7th Joint European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS)-Americas-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications.

Persistence to fingolimod compared with other disease modifying therapies in the Australian real-world setting using the MS base registry

2017

Conference Publication

The risk of relapse following on-treatment clinically silent lesions in patients with relapsing-remitting multiple sclerosis

Brown, J. W. L., Lugaresi, A., Horakova, D., Havrdova, E., Jokubaitis, V., Lechner-Scott, J., Trojano, M., Min, M., Shaw, C., Shuey, N., Slee, M., Mccombe, P., Van Pesch, V., Van Wijmeersch, B., Prevost, J., Moore, F., Prat, A., Girard, M., Duquette, P., Ayrignac, X., Sempere, A. Perez, Sanchez-Menoyo, J. L., Ramo-Tello, C., Csepany, T., Hutchinson, M., De Luca, G., Bergamaschi, R., Granella, F., Curti, E. ... Kalincik, T. (2017). The risk of relapse following on-treatment clinically silent lesions in patients with relapsing-remitting multiple sclerosis. 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517733228

The risk of relapse following on-treatment clinically silent lesions in patients with relapsing-remitting multiple sclerosis

2017

Conference Publication

Gelsolin, clusterin and Cd5L are the potential plasma biomarkers of amyotrophic lateral sclerosis with and without cognitive impairment

Xu, Zhouwei, Lee, Aven, Henderson, Robert and McCombe, Pamela (2017). Gelsolin, clusterin and Cd5L are the potential plasma biomarkers of amyotrophic lateral sclerosis with and without cognitive impairment. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, Australia, 9-12 May 2017. London, United Kingdom: B M J Group. doi: 10.1136/jnnp-2017-316074.34

Gelsolin, clusterin and Cd5L are the potential plasma biomarkers of amyotrophic lateral sclerosis with and without cognitive impairment

2017

Conference Publication

Alemtuzumab demonstrated durable efficacy and safety in CARE-MS I patients switching from SC IFNB-1a: 5-year follow-up after alemtuzumab (TOPAZ study)

Oreja-Guevara, C., Alroughani, R., Brassat, D., Boyko, A. N., McCombe, P., Steingo, B., Van Wijmeersch, B., Margolin, D. H., Daizadeh, N., Rodriguez, C. E. and Vermersch, P. (2017). Alemtuzumab demonstrated durable efficacy and safety in CARE-MS I patients switching from SC IFNB-1a: 5-year follow-up after alemtuzumab (TOPAZ study). 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517731406

Alemtuzumab demonstrated durable efficacy and safety in CARE-MS I patients switching from SC IFNB-1a: 5-year follow-up after alemtuzumab (TOPAZ study)

2017

Conference Publication

Pregnancy incidence, therapy exposure and post-partum relapse risk: a 12-year retrospective multicentre analysis

Jokubaitis, Vilija, Ai-Lan Nguyen,, Kalincik, Tomas, van der Walt, Anneke, Lechner-Scott, Jeannette, Barnett, Michael, McCombe, Pamela, Vucic, Steve, Hodgkinson, Suzanne, Slee, Mark, Skibina, Olga, Shaw, Cameron and Butzkueven, Helmut (2017). Pregnancy incidence, therapy exposure and post-partum relapse risk: a 12-year retrospective multicentre analysis. Progress in MS Research Conference, Sydney, Australia, 11-13 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517734699

Pregnancy incidence, therapy exposure and post-partum relapse risk: a 12-year retrospective multicentre analysis

2017

Conference Publication

Screening for cognitive and behavioural impairment in amyotrophic lateral sclerosis: frequency of abnormality and effect on survival

Xu, Zhouwei, Alruwaili, Ashwag, Henderson, Robert and McCombe, Pamela (2017). Screening for cognitive and behavioural impairment in amyotrophic lateral sclerosis: frequency of abnormality and effect on survival. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, QLD, Australia, 9-12 May 2017. London, United Kingdom: BMJ Group. doi: 10.1136/jnnp-2017-316074.29

Screening for cognitive and behavioural impairment in amyotrophic lateral sclerosis: frequency of abnormality and effect on survival

2017

Conference Publication

Cladribine versus fingolimod, natalizumab and interferon beta for multiple sclerosis

Kalincik, T., Jokubaitis, V., Spelman, T., Horakova, D., Havrdova, E., Trojano, M., Lechner-Scott, J., Lugaresi, A., Prat, A., Girard, M., Duquette, P., Grammond, P., Solaro, C., Grand'Maison, F., Hupperts, R., Prevost, J., Sola, P., Ferraro, D., Terzi, M., Butler, E., Slee, M., Kermode, A., Fabis-Pedrini, M., McCombe, P., Barnett, M., Shaw, C., Hodgkinson, S. and Butzkueven, H. (2017). Cladribine versus fingolimod, natalizumab and interferon beta for multiple sclerosis. 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517731406

Cladribine versus fingolimod, natalizumab and interferon beta for multiple sclerosis

2017

Conference Publication

Risk of secondary progressive multiple sclerosis: a longitudinal study

Fambiatos, A., Jokubaitis, V., Spelman, T., Horakova, D., Havrdova, E., Trojano, M., Prat, A., Girard, M., Duquette, P., Lugaresi, A., Izquierdo, G., Grand'Maison, F., Grammond, P., Sola, P., Ferraro, D., Alroughani, R., Terzi, M., Hupperts, R., Boz, C., Lechner-Scott, J., Pucci, E., Bergamaschi, R., Van Pesch, V., Ozakbas, S., Granella, F., Ramo, C., Turkoglu, R., Iuliano, G., Spitaleri, D. ... Kalincik, T. (2017). Risk of secondary progressive multiple sclerosis: a longitudinal study. 7th Joint European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS)-Americas-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications.

Risk of secondary progressive multiple sclerosis: a longitudinal study

2017

Conference Publication

Hypermetabolism in Motor Neurone Disease Is Associated with a Greater Functional Decline But Not Weight Loss

Ioannides, Zara A., Ngo, Shyuan T., Henderson, Robert D., McCombe, Pamela A. and Steyn, Frederik J. (2017). Hypermetabolism in Motor Neurone Disease Is Associated with a Greater Functional Decline But Not Weight Loss. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, Australia, May 09-12, 2017. LONDON: BMJ PUBLISHING GROUP. doi: 10.1136/jnnp-2017-316074.18

Hypermetabolism in Motor Neurone Disease Is Associated with a Greater Functional Decline But Not Weight Loss

2017

Conference Publication

Effectiveness of fingolimod, dimethyl fumarate and teriflunomide in relapsing-remitting multiple sclerosis: a comparative longitudinal study

Kalincik, T., Spelman, T., Jokubaitis, V., Horakova, D., Havrdova, E., Izquierdo, G., Prat, A., Girard, M., Duquette, P., Lugaresi, A., Grammond, P., Alroughani, R., Lechner-Scott, J., Prevost, J., Terzi, M., Grand'Maison, F., Boz, C., Trojano, M., Van Wijmeersch, B., Pucci, E., Granella, F., Turkoglu, R., Sola, P., Ferraro, D., McCombe, P., Solaro, C., Van Pesch, V., Ozakbas, S., Slee, M. ... Butzkueven, H. (2017). Effectiveness of fingolimod, dimethyl fumarate and teriflunomide in relapsing-remitting multiple sclerosis: a comparative longitudinal study. 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517731404

Effectiveness of fingolimod, dimethyl fumarate and teriflunomide in relapsing-remitting multiple sclerosis: a comparative longitudinal study

2017

Conference Publication

The risk of overestimating fatness in motor neurone disease: longitudinal assessments of body composition

Ioannides, Zara A., Steyn, Frederik J., Henderson, Robert D., McCombe, Pamela A. and Ngo, Shyuan T. (2017). The risk of overestimating fatness in motor neurone disease: longitudinal assessments of body composition. Annual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN), Gold Coast, Australia, 9-12 May 2017. London, United Kingdom: B M J Group. doi: 10.1136/jnnp-2017-316074.35

The risk of overestimating fatness in motor neurone disease: longitudinal assessments of body composition

2017

Conference Publication

Alemtuzumab durably improves clinical outcomes in patients with active RRMS in the absence of continuous treatment: 7-year follow-up of CARE-MS-I patients (TOPAZ study)

Coles, A. J., Boyko, A. N., De Seze, J., Hartung, H-P., Havrdova, E., Inshasi, J. S., McCombe, P., Montalban, X., Pozzilli, C., Selmaj, K. W., Vermersch, P., Margolin, D. H., Daizadeh, N., Rodriguez, C. E. and Van Wijmeersch, B. (2017). Alemtuzumab durably improves clinical outcomes in patients with active RRMS in the absence of continuous treatment: 7-year follow-up of CARE-MS-I patients (TOPAZ study). 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517731406

Alemtuzumab durably improves clinical outcomes in patients with active RRMS in the absence of continuous treatment: 7-year follow-up of CARE-MS-I patients (TOPAZ study)

2017

Conference Publication

The effect of disease-modifying treatments on conversion to secondary progressive multiple sclerosis

Brown, J. W. L., Coles, A., Horakova, D., Havrdova, E., Trojano, M., Izquierdo, G., Prat, A., Girard, M., Hupperts, R., Van Pesch, V., Ferraro, D., Alroughani, R., Bergamaschi, R., Pucci, E., Iuliano, G., Lechner-Scott, J., Spelman, T., Jokubaitis, V., Ramo-Tello, C., Spitaleri, D., Granella, F., Solaro, C., Ampapa, R., Deri, N., McCombe, P., Petersen, T., Van Wijmeersch, B., Prevost, J., Sanchez-Menoyo, J. L. ... Robsertson, N. (2017). The effect of disease-modifying treatments on conversion to secondary progressive multiple sclerosis. 7th Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS), Paris, France, 25-28 October 2017. London, United Kingdom: Sage Publications. doi: 10.1177/1352458517731283

The effect of disease-modifying treatments on conversion to secondary progressive multiple sclerosis

2016

Conference Publication

Pregnancy Outcomes in Patients with RRMS Who Received Alemtuzumab in the Clinical Development Program

Oh, Jiwon, Achiron, Anat, Chambers, Christina, Fox, Edward, McCombe, Pamela, Otero, Susana, Margolin, David, Kasten, Linda and Compston, D. Alastair (2016). Pregnancy Outcomes in Patients with RRMS Who Received Alemtuzumab in the Clinical Development Program. AAN 68th Annual Meeting, Vancouver, Canada, 15 - 21 April 2016. Philadelphia, PA United States: Wolters Kluwer. doi: 10.1212/wnl.86.16_supplement.s24.008

Pregnancy Outcomes in Patients with RRMS Who Received Alemtuzumab in the Clinical Development Program