2014 Journal Article RNAi therapies: drugging the undruggableWu, S. Y., Lopez-Berestein, G., Calin, G. A. and Sood, A. K. (2014). RNAi therapies: drugging the undruggable. Science Translational Medicine, 6 (240), 240ps7-240ps7. doi: 10.1126/scitranslmed.3008362 |
2014 Journal Article 2′-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activityWu, Sherry Y., Yang, Xianbin, Gharpure, Kshipra M., Hatakeyama, Hiroto, Egli, Martin, McGuire, Michael H., Nagaraja, Archana S., Miyake, Takahito M., Rupaimoole, Rajesha, Pecot, Chad V., Taylor, Morgan, Pradeep, Sunila, Sierant, Malgorzata, Rodriguez-Aguayo, Cristian, Choi, Hyun J., Previs, Rebecca A., Armaiz-Pena, Guillermo N., Huang Li, Martinez, Carlos, Hassell Tom, Ivan, Cristina, Sehgal, Vasudha, Singhania, Richa, Han, Hee-Dong, Su, Chang, Kim, Ji Hoon, Dalton, Heather J., Kovvali, Chandra, Keyomarsi, Khandan ... Sood, Anil K. (2014). 2′-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity. Nature Communications, 5 (1) 3459. doi: 10.1038/ncomms4459 |
2014 Journal Article Autocrine effects of tumor-derived complementCho, Min Soon, Vasquez, Hernan G., Rupaimoole, Rajesha, Pradeep, Sunila, Wu, Sherry, Zand, Behrouz, Han, Hee-Dong, Rodriguez-Aguayo, Cristian, Bottsford-Miller, Justin, Huang, Jie, Miyake, Takahito, Choi, Hyun-Jin, Dalton, Heather J., Ivan, Cristina, Baggerly, Keith, Lopez-Berestein, Gabriel, Sood, Anil K. and Afshar-Kharghan, Vahid (2014). Autocrine effects of tumor-derived complement. Cell Reports, 6 (6), 1085-1095. doi: 10.1016/j.celrep.2014.02.014 |
2013 Journal Article Therapeutic synergy between microRNA and siRNA in ovarian cancer treatmentNishimura, Masato, Jung, Eun-Jung, Shah, Maitri Y., Lu, Chunhua, Spizzo, Riccardo, Shimizu, Masayoshi, Han, Hee Dong, Ivan, Cristina, Rossi, Simona, Zhang, Xinna, Nicoloso, Milena S., Wu, Sherry Y., Almeida, Maria Ines, Bottsford-Miller, Justin, Pecot, Chad V., Zand, Behrouz, Matsuo, Koji, Shahzad, Mian M., Jennings, Nicholas B., Rodriguez-Aguayo, Cristian, Lopez-Berestein, Gabriel, Sood, Anil K. and Calin, George A. (2013). Therapeutic synergy between microRNA and siRNA in ovarian cancer treatment. Cancer Discovery, 3 (11), 1302-1315. doi: 10.1158/2159-8290.CD-13-0159 |
2013 Journal Article Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancerKim, Hyun Seok, Mendiratta, Saurabh, Kim, Jiyeon, Pecot, Chad Victor, Larsen, Jill E., Zubovych, Iryna, Seo, Bo Yeun, Kim, Jimi, Eskiocak, Banu, Chung, Hannah, McMillan, Elizabeth, Wu, Sherry, De Brabander, Jef, Komurov, Kakajan, Toombs, Jason E., Wei, Shuguang, Peyton, Michael, Williams, Noelle, Gazdar, Adi F., Posner, Bruce A., Brekken, Rolf A., Sood, Anil K., Deberardinis, Ralph J., Roth, Michael G., Minna, John D. and White, Michael A. (2013). Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer. Cell, 155 (3), 552-566. doi: 10.1016/j.cell.2013.09.041 |
2013 Journal Article Role of focal adhesion kinase in regulating YB-1-mediated paclitaxel resistance in ovarian cancerKang, Yu, Hu, Wei, Ivan, Cristina, Dalton, Heather J., Miyake, Takahito, Pecot, Chad V., Zand, Behrouz, Liu, Tao, Huang, Jie, Jennings, Nicholas B., Rupaimoole, Rajesha, Taylor, Morgan, Pradeep, Sunila, Wu, Sherry Y., Lu, Chunhua, Wen, Yunfei, Huang, Jianfei, Liu, Jinsong and Sood, Anil K. (2013). Role of focal adhesion kinase in regulating YB-1-mediated paclitaxel resistance in ovarian cancer. JNCI-Journal of the National Cancer Institute, 105 (19), 1485-1495. doi: 10.1093/jnci/djt210 |
2013 Journal Article Tumour angiogenesis regulation by the miR-200 familyPecot, Chad V., Rupaimoole, Rajesha, Yang, Da, Akbani, Rehan, Ivan, Cristina, Lu, Chunhua, Wu, Sherry, Han, Hee-Dong, Shah, Maitri Y., Rodriguez-Aguayo, Cristian, Bottsford-Miller, Justin, Liu, Yuexin, Kim, Sang Bae, Unruh, Anna, Gonzalez-Villasana, Vianey, Huang, Li, Zand, Behrouz, Moreno-Smith, Myrthala, Mangala, Lingegowda S., Taylor, Morgan, Dalton, Heather J., Sehgal, Vasudha, Wen, Yunfei, Kang, Yu, Baggerly, Keith A., Lee, Ju-Seog, Ram, Prahlad T., Ravoori, Murali K., Kundra, Vikas ... Sood, Anil K. (2013). Tumour angiogenesis regulation by the miR-200 family. Nature Communications, 4 (1) 2427. doi: 10.1038/ncomms3427 |
2013 Journal Article A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesisMasiero, Massimo, Simões, Filipa Costa, Han, Hee Dong, Snell, Cameron, Peterkin, Tessa, Bridges, Esther, Mangala, Lingegowda S., Wu, Sherry Yen-Yao, Pradeep, Sunila, Li, Demin, Han, Cheng, Dalton, Heather, Lopez-Berestein, Gabriel, Tuynman, Jurriaan B., Mortensen, Neil, Li, Ji-Liang, Patient, Roger, Sood, Anil K., Banham, Alison H., Harris, Adrian L. and Buffa, Francesca M. (2013). A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis. Cancer Cell, 24 (2), 229-241. doi: 10.1016/j.ccr.2013.06.004 |
2013 Journal Article Efficient biodistribution and gene silencing in the lung epithelium via intravenous liposomal delivery of siRNAMcCaskill, Jana, Singhania, Richa, Burgess, Melinda, Allavena, Rachel, Wu, Sherry, Blumenthal, Antje and McMillan, Nigel A. J. (2013). Efficient biodistribution and gene silencing in the lung epithelium via intravenous liposomal delivery of siRNA. Molecular Therapy - Nucleic Acid, 2 (1) e96, e96. doi: 10.1038/mtna.2013.22 |
2013 Journal Article The use of lipid-based nanocarriers for targeted pain therapiesHua, Susan and Wu, Sherry Y. (2013). The use of lipid-based nanocarriers for targeted pain therapies. Frontiers in Pharmacology, 4. doi: 10.3389/fphar.2013.00143 |
2012 Journal Article siRNA-induced immunostimulation through TLR7 promotes antitumoral activity against HPV-driven tumors in vivoKhairuddin, Norliana, Gantier, Michael P., Blake, Stephen J., Wu, Sherry Y., Behlke, Mark A., Williams, Bryan R. G. and McMillan, Nigel A. J. (2012). siRNA-induced immunostimulation through TLR7 promotes antitumoral activity against HPV-driven tumors in vivo. Immunology and Cell Biology, 90 (2), 187-196. doi: 10.1038/icb.2011.19 |
2012 Journal Article New roles opined for OPCMLWu, Sherry Y. and Sood, Anil K. (2012). New roles opined for OPCML. Cancer Discovery, 2 (2), 115-116. doi: 10.1158/2159-8290.CD-11-0356 |
2011 Journal Article Vaginal delivery of siRNA using a novel PEGylated lipoplex-entrapped alginate scaffold systemWu, Sherry Y., Chang, Hsin-I, Burgess, Melinda and McMillan, Nigel A. J. (2011). Vaginal delivery of siRNA using a novel PEGylated lipoplex-entrapped alginate scaffold system. Journal of Controlled Release, 155 (3), 418-426. doi: 10.1016/j.jconrel.2011.02.002 |
2011 Journal Article Systemic delivery of E6/7 siRNA using novel lipidic particles and its application with cisplatin in cervical cancer mouse modelsWu, S. Y., Singhania, A., Burgess, M., Putral, L. N., Kirkpatrick, C., Davies, N. M. and McMillan, N. A. J. (2011). Systemic delivery of E6/7 siRNA using novel lipidic particles and its application with cisplatin in cervical cancer mouse models. Gene Therapy, 18 (1), 14-22. doi: 10.1038/gt.2010.113 |
2011 Journal Article Effective delivery of PEGylated siRNA-containing Lipoplexes to extraperitoneal tumours following intraperitoneal administrationSinghania, Akul, Wu, Sherry Y. and McMillan, Nigel A. J. (2011). Effective delivery of PEGylated siRNA-containing Lipoplexes to extraperitoneal tumours following intraperitoneal administration. Journal of Drug Delivery, 2011, 192562.1-192562.7. doi: 10.1155/2011/192562 |
2009 Journal Article Lipidic Systems for In Vivo siRNA DeliveryWu, SY and McMillan, NAJ (2009). Lipidic Systems for In Vivo siRNA Delivery. AAPS JOURNAL, 11 (4), 639-652. doi: 10.1208/s12248-009-9140-1 |
2009 Journal Article Development of a novel method for formulating stable siRNA-loaded lipid particles for In vivo useWu, Sherry Y., Putral, Lisa N., Liang, Mingtao, Chang, Hsin-I, Davies, Nigel M. and McMillan, Nigel A.J. (2009). Development of a novel method for formulating stable siRNA-loaded lipid particles for In vivo use. Pharmaceutical Research, 26 (3), 512-522. doi: 10.1007/s11095-008-9766-1 |