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2024

Journal Article

Enhancing precision targeting of ovarian cancer tumor cells in vivo through extracellular vesicle engineering

Alharbi, Mona, Lai, Andrew, Godbole, Nihar, Guanzon, Dominic, Nair, Soumyalekshmi, Zuñiga, Felipe, Quinn, Alexander, Yang, Mengliu, Wu, Sherry Y. and Salomon, Carlos (2024). Enhancing precision targeting of ovarian cancer tumor cells in vivo through extracellular vesicle engineering. International Journal of Cancer, 155 (8), 1510-1523. doi: 10.1002/ijc.35055

Enhancing precision targeting of ovarian cancer tumor cells in vivo through extracellular vesicle engineering

2024

Journal Article

Let-7i enhances anti-tumour immunity and suppresses ovarian tumour growth

Wilkinson, Andrew N., Chen, Rui, Coleborn, Elaina, Neilson, Trent, Le, Khang, Bhavsar, Chintan, Wang, Yue, Atluri, Sharat, Irgam, Gowri, Wong, Kiefer, Yang, Da, Steptoe, Raymond and Wu, Sherry Y. (2024). Let-7i enhances anti-tumour immunity and suppresses ovarian tumour growth. Cancer Immunology, Immunotherapy, 73 (5) 80, 1-12. doi: 10.1007/s00262-024-03674-w

Let-7i enhances anti-tumour immunity and suppresses ovarian tumour growth

2023

Journal Article

miR-146a inhibits ovarian tumour growth in vivo via targeting immunosuppressive neutrophils and enhancing CD8+ T cell infiltration

Chen, Rui, Coleborn, Elaina, Bhavsar, Chintan, Wang, Yue, Alim, Louisa, Wilkinson, Andrew N., Tran, Michelle A., Irgam, Gowri, Atluri, Sharat, Wong, Kiefer, Shim, Jae-Jun, Adityan, Siddharth, Lee, Ju-Seog, Overwijk, Willem W., Steptoe, Raymond, Yang, Da and Wu, Sherry Y. (2023). miR-146a inhibits ovarian tumour growth in vivo via targeting immunosuppressive neutrophils and enhancing CD8+ T cell infiltration. Molecular Therapy - Oncolytics, 31 100725, 1-15. doi: 10.1016/j.omto.2023.09.001

miR-146a inhibits ovarian tumour growth in vivo via targeting immunosuppressive neutrophils and enhancing CD8+ T cell infiltration

2022

Journal Article

Molecular analysis of short- versus long-term survivors of high-grade serous ovarian carcinoma

Stur, Elaine, Bayraktar, Emine, Dal Molin, Graziela Zibetti, Wu, Sherry Y., Mangala, Lingegowda S., Yao, Hui, Wang, Ying, Ram, Prahlad T., Corvigno, Sara, Chen, Hu, Liang, Han, Tworoger, Shelley S., Levine, Douglas A., Lutgendorf, Susan K., Liu, Jinsong, Moore, Kathleen N., Baggerly, Keith A., Karlan, Beth Y. and Sood, Anil K. (2022). Molecular analysis of short- versus long-term survivors of high-grade serous ovarian carcinoma. Cancers, 14 (17) 4198, 4198. doi: 10.3390/cancers14174198

Molecular analysis of short- versus long-term survivors of high-grade serous ovarian carcinoma

2021

Journal Article

Gene body methylation of the lymphocyte-specific gene CARD11 results in its overexpression and regulates cancer mTOR signaling

McGuire, Michael H., Dasari, Santosh K., Yao, Hui, Wen, Yunfei, Mangala, Lingegowda S., Bayraktar, Emine, Ma, Wencai, Ivan, Cristina, Shoshan, Einav, Wu, Sherry Y., Jonasch, Eric, Bar-Eli, Menashe, Wang, Jing, Baggerly, Keith A. and Sood, Anil K. (2021). Gene body methylation of the lymphocyte-specific gene CARD11 results in its overexpression and regulates cancer mTOR signaling. Molecular Cancer Research, 19 (11), 1917-1928. doi: 10.1158/1541-7786.MCR-20-0753

Gene body methylation of the lymphocyte-specific gene CARD11 results in its overexpression and regulates cancer mTOR signaling

2021

Journal Article

CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance

Ma, Shaolin, Mangala, Lingegowda S., Hu, Wen, Bayaktar, Emine, Yokoi, Akira, Hu, Wei, Pradeep, Sunila, Lee, Sanghoon, Piehowski, Paul D., Villar-Prados, Alejandro, Wu, Sherry Y., McGuire, Michael H., Lara, Olivia D., Rodriguez-Aguayo, Cristian, LaFargue, Christopher J., Jennings, Nicholas B., Rodland, Karin D., Liu, Tao, Kundra, Vikas, Ram, Prahlad T., Ramakrishnan, Sundaram, Lopez-Berestein, Gabriel, Coleman, Robert L. and Sood, Anil K. (2021). CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance. Cell Reports, 36 (7). doi: 10.1016/j.celrep.2021.109549

CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance

2021

Journal Article

Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype

Ma, Shaolin, McGuire, Michael H., Mangala, Lingegowda S., Lee, Sanghoon, Stur, Elaine, Hu, Wen, Bayraktar, Emine, Villar-Prados, Alejandro, Ivan, Cristina, Wu, Sherry Y., Yokoi, Akira, Dasari, Santosh K., Jennings, Nicholas B., Liu, Jinsong, Lopez-Berestein, Gabriel, Ram, Prahlad and Sood, Anil K. (2021). Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype. Cell Reports, 34 (6). doi: 10.1016/j.celrep.2021.108726

Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype

2020

Journal Article

HIF and COX-2 expression in triple negative breast cancer cells with hypoxia and 5-fluorouracil

Mori, Noriko, Mironchik, Yelena, Wildes, Flonné, Wu, Sherry Y., Mori, Kanami, Krishnamachary, Balaji and Bhujwalla, Zaver M. (2020). HIF and COX-2 expression in triple negative breast cancer cells with hypoxia and 5-fluorouracil. Current Cancer Reports, 2 (1), 54-63. doi: 10.25082/CCR.2020.01.005

HIF and COX-2 expression in triple negative breast cancer cells with hypoxia and 5-fluorouracil

2020

Journal Article

Nano-therapeutics for modulating the tumour microenvironment: design, development, and clinical translation

Adityan, Siddharth, Tran, Michelle, Bhavsar, Chintan and Wu, Sherry Y. (2020). Nano-therapeutics for modulating the tumour microenvironment: design, development, and clinical translation. Journal of Controlled Release, 327 (Acta Biomater. 62 2017), 512-532. doi: 10.1016/j.jconrel.2020.08.016

Nano-therapeutics for modulating the tumour microenvironment: design, development, and clinical translation

2020

Journal Article

The hidden role of paxillin: localization to nucleus promotes tumor angiogenesis

Noh, Kyunghee, Duc-Hiep Bach, , Choi, Hyun-Jin, Kim, Mark S., Wu, Sherry Y., Pradeep, Sunila, Ivan, Cristina, Cho, Min-Soon, Bayraktar, Emine, Rodriguez-Aguayo, Cristian, Dasari, Santosh K., Stur, Elaine, Mangala, Lingegowda S., Lopez-Berestein, Gabriel and Sood, Anil K. (2020). The hidden role of paxillin: localization to nucleus promotes tumor angiogenesis. Oncogene, 40 (2), 384-395. doi: 10.1038/s41388-020-01517-3

The hidden role of paxillin: localization to nucleus promotes tumor angiogenesis

2020

Journal Article

Characterization of and isolation methods for plant leaf nanovesicles and small extracellular vesicles

Liu, Yuan, Wu, Sherry, Koo, Yeonjong, Yang, An, Dai, Yanwan, Khant, Htet, Osman, Samantha R., Chowdhury, Mamur, Wei, Haichao, Li, Yang, Court, Karem, Hwang, Elaine, Wen, Yunfei, Dasari, Santosh K., Nguyen, Michael, Tang, E. Chia-Cheng, Chehab, E. Wassim, de Val, Natalia, Braam, Janet and Sood, Anil K. (2020). Characterization of and isolation methods for plant leaf nanovesicles and small extracellular vesicles. Nanomedicine-Nanotechnology Biology and Medicine, 29 102271. doi: 10.1016/j.nano.2020.102271

Characterization of and isolation methods for plant leaf nanovesicles and small extracellular vesicles

2020

Journal Article

NRG1/ERBB3 pathway activation induces acquired resistance to XPO1 inhibitors

Miyake, Takahito M., Pradeep, Sunila, Bayraktar, Emine, Stur, Elaine, Handley, Katelyn F., Wu, Sherry Y., Rodriguez-Aguayo, Cristian, Lee, Ju-Seog, Lopez-Berestein, Gabriel, Coleman, Robert L. and Sood, Anil K. (2020). NRG1/ERBB3 pathway activation induces acquired resistance to XPO1 inhibitors. Molecular Cancer Therapeutics, 19 (8), 1727-1735. doi: 10.1158/1535-7163.MCT-19-0977

NRG1/ERBB3 pathway activation induces acquired resistance to XPO1 inhibitors

2019

Journal Article

Copper-64 labeled PEGylated exosomes for in vivo positron emission tomography and enhanced tumor retention

Shi, Sixiang, Li, Tingting, Wen, Xiaofei, Wu, Sherry Y., Xiong, Chiyi, Zhao, Jun, Lincha, Victor R., Chow, Diana S., Liu, Yiyao, Sood, Anil K. and Li, Chun (2019). Copper-64 labeled PEGylated exosomes for in vivo positron emission tomography and enhanced tumor retention. Bioconjugate Chemistry, 30 (10), 2675-2683. doi: 10.1021/acs.bioconjchem.9b00587

Copper-64 labeled PEGylated exosomes for in vivo positron emission tomography and enhanced tumor retention

2019

Journal Article

Auranofin improves overall survival when combined with standard of care in a pilot study involving dogs with osteosarcoma

Endo-Munoz, Liliana, Bennett, Tristram C., Topkas, Eleni, Wu, Sherry Y., Thamm, Douglas H., Brockley, Laura, Cooper, Maureen, Sommerville, Scott, Thomson, Maurine, O'Connell, Kathleen, Lane, Amy, Bird, Guy, Peaston, Anne, Matigian, Nicholas, Straw, Rodney C. and Saunders, Nicholas A. (2019). Auranofin improves overall survival when combined with standard of care in a pilot study involving dogs with osteosarcoma. Veterinary and Comparative Oncology, 18 (2) vco.12533, 206-213. doi: 10.1111/vco.12533

Auranofin improves overall survival when combined with standard of care in a pilot study involving dogs with osteosarcoma

2019

Journal Article

Pan-cancer genomic analysis links 3'UTR DNA methylation with increased gene expression in T cells

McGuire, Michael H., Herbrich, Shelley M., Dasari, Santosh K., Wu, Sherry Y., Wang, Ying, Rupaimoole, Rajesha, Lopez-Berestein, Gabriel, Baggerly, Keith A. and Sood, Anil K. (2019). Pan-cancer genomic analysis links 3'UTR DNA methylation with increased gene expression in T cells. Ebiomedicine, 43, 127-137. doi: 10.1016/j.ebiom.2019.04.045

Pan-cancer genomic analysis links 3'UTR DNA methylation with increased gene expression in T cells

2019

Journal Article

Predicting novel therapies and targets: regulation of notch3 by the Bromodomain protein BRD4

Villar-Prados, Alejandro, Wu, Sherry Y., Court, Karem A., Ma, Shaolin, LaFargue, Christopher, Chowdhury, Mamur A., Engelhardt, Margaret I., Ivan, Cristina, Ram, Prahlad T., Wang, Ying, Baggerly, Keith, Rodriguez-Aguayo, Cristian, Lopez-Berestein, Gabriel, Ming-Yang, Shyh, Maloney, David J., Yoshioka, Makoto, Strovel, Jeffrey W., Roszik, Jason and Sood, Anil K. (2019). Predicting novel therapies and targets: regulation of notch3 by the Bromodomain protein BRD4. Molecular Cancer Therapeutics, 18 (2), 421-436. doi: 10.1158/1535-7163.MCT-18-0365

Predicting novel therapies and targets: regulation of notch3 by the Bromodomain protein BRD4

2018

Journal Article

Advances and challenges in nanomedicine

Hua, Susan and Wu, Sherry Y. (2018). Advances and challenges in nanomedicine. Frontiers in Pharmacology, 9 (Nov) 1397, 1397. doi: 10.3389/fphar.2018.01397

Advances and challenges in nanomedicine

2018

Journal Article

The advances and challenges in utilizing exosomes for delivering cancer therapeutics

Yang, Mengliu and Wu, Sherry Y. (2018). The advances and challenges in utilizing exosomes for delivering cancer therapeutics. Frontiers in Pharmacology, 9 (JUL) 735, 735. doi: 10.3389/fphar.2018.00735

The advances and challenges in utilizing exosomes for delivering cancer therapeutics

2017

Journal Article

Immune cell profiling in cancer: molecular approaches to cell-specific identification

Lyons, Yasmin A., Wu, Sherry Y., Overwijk, Willem W., Baggerly, Keith A. and Sood, Anil K. (2017). Immune cell profiling in cancer: molecular approaches to cell-specific identification. Npj Precision Oncology, 1 (26) 26. doi: 10.1038/s41698-017-0031-0

Immune cell profiling in cancer: molecular approaches to cell-specific identification

2017

Journal Article

PRKCI promotes immune suppression in ovarian cancer

Sarkar, Sharmistha, Bristow, Christopher A., Dey, Prasenjit, Rai, Kunal, Perets, Ruth, Ramirez-Cardenas, Alejandra, Malasi, Shruti, Huang-Hobbs, Emmet, Haemmerle, Monika, Wu, Sherry Y., McGuire, Michael, Protopopov, Alexei, Jiang, Shan, Liu, Joyce F., Hirsch, Michelle S., Chang, Qing, Lazar, Alexander J., Sood, Anil K., Drapkin, Ronny, DePinho, Ronald, Draetta, Giulio and Chin, Lynda (2017). PRKCI promotes immune suppression in ovarian cancer. Genes and Development, 31 (11), 1109-1121. doi: 10.1101/gad.296640.117

PRKCI promotes immune suppression in ovarian cancer