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2019

Journal Article

Single-cell RNA sequencing reveals cell type-specific HPV expression in hyperplastic skin lesions

Devitt, Katharina, Hanson, Sarah J., Tuong, Zewen K., McMeniman, Erin, Soyer, H. Peter, Frazer, Ian H. and Lukowski, Samuel W. (2019). Single-cell RNA sequencing reveals cell type-specific HPV expression in hyperplastic skin lesions. Virology, 537, 14-19. doi: 10.1016/j.virol.2019.08.007

Single-cell RNA sequencing reveals cell type-specific HPV expression in hyperplastic skin lesions

2019

Journal Article

Microprojection arrays applied to skin generate mechanical stress, induce an inflammatory transcriptome and cell death, and improve vaccine-induced immune responses

Ng, Hwee-Ing, Tuong, Zewen K., Fernando, Germain J. P., Depelsenaire, Alexandra C. I., Meliga, Stefano C., Frazer, Ian H. and Kendall, Mark A. F. (2019). Microprojection arrays applied to skin generate mechanical stress, induce an inflammatory transcriptome and cell death, and improve vaccine-induced immune responses. npj Vaccines, 4 (1) 41, 41. doi: 10.1038/s41541-019-0134-4

Microprojection arrays applied to skin generate mechanical stress, induce an inflammatory transcriptome and cell death, and improve vaccine-induced immune responses

2019

Conference Publication

2125. Staphylococcus Species Identification by Fourier Transform Infrared (FTIR) Spectroscopic Techniques: A Cross-Lab Study

Tsutsumi, Tamao, Shah, Alok, Lam, Lisa M T, Schlebusch, Sanmarie, Krueger, Annika, Frazer, Ian, Hugenholtz, Phil, Soyer, H Peter, Morrison, Mark, Hill, Michelle, Sedman, Jacqueline and Ismail, Ashraf (2019). 2125. Staphylococcus Species Identification by Fourier Transform Infrared (FTIR) Spectroscopic Techniques: A Cross-Lab Study. IDWeek 2019, Washington, DC, United States, 2-6 October 2019. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ofid/ofz360.1805

2125. Staphylococcus Species Identification by Fourier Transform Infrared (FTIR) Spectroscopic Techniques: A Cross-Lab Study

2019

Journal Article

Human papillomavirus infection among head and neck squamous cell carcinomas in southern China

Ni, Guoying, Huang, Kunsong, Luan, Yi, Cao, Zaizai, Chen, Shu, Ma, Bowei, Yuan, Jianwei, Wu, Xiaolian, Chen, Guoqiang, Wang, Tianfang, Li, Hejie, Walton, Shelley, Liu, Fang, Chen, Bobei, Wang, Yuejian, Pan, Xuan, Liu, Xiaosong and Frazer, Ian H. (2019). Human papillomavirus infection among head and neck squamous cell carcinomas in southern China. PLoS ONE, 14 (9) e0221045, e0221045. doi: 10.1371/journal.pone.0221045

Human papillomavirus infection among head and neck squamous cell carcinomas in southern China

2019

Journal Article

Papillomavirus immune evasion strategies target the infected cell and the local immune system

Zhou, Chenhao, Tuong, Zewen Kelvin and Frazer, Ian Hector (2019). Papillomavirus immune evasion strategies target the infected cell and the local immune system. Frontiers in Oncology, 9 682, 682. doi: 10.3389/fonc.2019.00682

Papillomavirus immune evasion strategies target the infected cell and the local immune system

2019

Journal Article

The HPV vaccine story

Frazer, Ian H. (2019). The HPV vaccine story. ACS Pharmacology and Translational Science, 2 (3) acsptsci.9b00032, 210-212. doi: 10.1021/acsptsci.9b00032

The HPV vaccine story

2019

Journal Article

High-risk human papillomavirus detection in oropharyngeal cancers: comparison of saliva sampling methods

Tang, Kai Dun, Kenny, Liz, Frazer, Ian H. and Punyadeera, Chamindie (2019). High-risk human papillomavirus detection in oropharyngeal cancers: comparison of saliva sampling methods. Head and Neck, 41 (5), 1484-1489. doi: 10.1002/hed.25578

High-risk human papillomavirus detection in oropharyngeal cancers: comparison of saliva sampling methods

2019

Journal Article

Unlocking the potential of saliva-based test to detect HPV-16-driven oropharyngeal cancer

Tang, Kai Dun, Baeten, Kurt, Kenny, Liz, Frazer, Ian H., Scheper, Gert and Punyadeera, Chamindie (2019). Unlocking the potential of saliva-based test to detect HPV-16-driven oropharyngeal cancer. Cancers, 11 (4) 473, 473. doi: 10.3390/cancers11040473

Unlocking the potential of saliva-based test to detect HPV-16-driven oropharyngeal cancer

2019

Journal Article

Pathways to a cancer-free future: a protocol for modelled evaluations to maximize the future impact of interventions on cervical cancer in Australia

Velentzis, Louiza S., Smith, Megan A., Simms, Kate T., Lew, Jie-Bin, Hall, Michaela, Hughes, Suzanne, Yuill, Susan, Killen, James, Keane, Adam, Butler, Katherine, Darlington-Brown, Jessica, Hui, Harriet, Brotherton, Julia M.L., Skinner, Rachel, Brand, Alison, Roeske, Lara, Heley, Stella, Carter, Jonathan, Bateson, Deborah, Frazer, Ian, Garland, Suzanne M., Guy, Rebecca, Hammond, Ian, Grogan, Paul, Arbyn, Marc, Castle, Philip E., Saville, Marion, Armstrong, Bruce K. and Canfell, Karen (2019). Pathways to a cancer-free future: a protocol for modelled evaluations to maximize the future impact of interventions on cervical cancer in Australia. Gynecologic Oncology, 152 (3), 465-471. doi: 10.1016/j.ygyno.2018.12.019

Pathways to a cancer-free future: a protocol for modelled evaluations to maximize the future impact of interventions on cervical cancer in Australia

2019

Conference Publication

The involvement of IFN-gamma and CXCR3 in the CD8(+) T-cell-mediated regression of squamous cell carcinoma

Zeng, Z., Cruz, J. G., Pett, N., Veitch, M., Frazer, I. H. and Wells, J. W. (2019). The involvement of IFN-gamma and CXCR3 in the CD8(+) T-cell-mediated regression of squamous cell carcinoma. 17th International Congress of Immunology (IUIS), Beijing, Peoples R China, 19-23 October 2019. Weinheim, Germany: Wiley.

The involvement of IFN-gamma and CXCR3 in the CD8(+) T-cell-mediated regression of squamous cell carcinoma

2018

Journal Article

Recruitment of antigen presenting cells to skin draining lymph node from HPV16E7-expressing skin requires E7-Rb interaction

Kuo, Paula, Teoh, Siok Min, Tuong, Zewen K., Leggatt, Graham R., Mattarollo, Stephen R. and Frazer, Ian H. (2018). Recruitment of antigen presenting cells to skin draining lymph node from HPV16E7-expressing skin requires E7-Rb interaction. Frontiers in Immunology, 9 2896, 2896. doi: 10.3389/fimmu.2018.02896

Recruitment of antigen presenting cells to skin draining lymph node from HPV16E7-expressing skin requires E7-Rb interaction

2018

Journal Article

HLA and KIR associations of cervical neoplasia

Bao, Xiao, Hanson, Aimee L., Madeleine, Margaret M., Wang, Sophia S., Schwartz, Stephen M., Newell, Felicity, Pettersson-Kymmer, Ulrika, Hemminki, Kari, Tiews, Sven, Steinberg, Winfried, Rader, Janet S., Castro, Felipe, Safaeian, Mahboobeh, Franco, Eduardo L., Coutlée, François, Ohlsson, Claes, Cortes, Adrian, Marshall, Mhairi, Mukhopadhyay, Pamela, Cremin, Katie, Johnson, Lisa G., Garland, Suzanne M., Tabrizi, Sepehr N., Wentzensen, Nicolas, Sitas, Freddy, Trimble, Cornelia, Little, Julian, Cruickshank, Maggie, Frazer, Ian H. ... Leo, Paul J. (2018). HLA and KIR associations of cervical neoplasia. The Journal of Infectious Diseases, 218 (12), 2006-2015. doi: 10.1093/infdis/jiy483

HLA and KIR associations of cervical neoplasia

2018

Journal Article

Examining the contribution of smoking and HPV towards the etiology of oral cavity squamous cell carcinoma using high-throughput sequencing: a prospective observational study

Zammit, Andrew P., Sinha, Rohit, Cooper, Caroline L., Perry, Christopher F. L., Frazer, Ian H. and Tuong, Zewen K. (2018). Examining the contribution of smoking and HPV towards the etiology of oral cavity squamous cell carcinoma using high-throughput sequencing: a prospective observational study. PLoS One, 13 (10) e0205406, e0205406. doi: 10.1371/journal.pone.0205406

Examining the contribution of smoking and HPV towards the etiology of oral cavity squamous cell carcinoma using high-throughput sequencing: a prospective observational study

2018

Journal Article

A natural history of actinic keratosis and cutaneous squamous cell carcinoma microbiomes

Wood, David L. A., Lachner, Nancy, Tan, Jean-Marie, Tang, Stephanie, Angel, Nicola, Laino, Antonia, Linedale, Richard, Lê Cao, Kim-Anh, Morrison, Mark, Frazer, Ian H., Soyer, H. Peter and Hugenholtz, Philip (2018). A natural history of actinic keratosis and cutaneous squamous cell carcinoma microbiomes. MBio, 9 (5) e01432-18. doi: 10.1128/mBio.01432-18

A natural history of actinic keratosis and cutaneous squamous cell carcinoma microbiomes

2018

Journal Article

The projected timeframe until cervical cancer elimination in Australia: a modelling study

Hall, Michaela T., Simms, Kate T., Lew, Jie-Bin, Smith, Megan A., Brotherton, Julia M. l., Saville, Marion, Frazer, Ian H. and Canfell, Karen (2018). The projected timeframe until cervical cancer elimination in Australia: a modelling study. The Lancet. Public health, 4 (1), e19-e27. doi: 10.1016/S2468-2667(18)30183-X

The projected timeframe until cervical cancer elimination in Australia: a modelling study

2018

Journal Article

An ex vivo human tumour assay reveals distinct patterns of EGFR trafficking in squamous cell carcinoma correlating to therapeutic outcomes

Joseph, Shannon R., Gaffney, Daniel, Barry, Rachael, Hu, Lingbo, Banushi, Blerida, Wells, James W., Lambie, Duncan, Strutton, Geoff, Porceddu, Sandro V., Burmeister, Bryan, Leggatt, Graham R., Schaider, Helmut, Dolcetti, Riccardo, Frazer, Ian H., Saunders, Nicholas A., Foote, Matthew, Soyer, H. Peter and Simpson, Fiona (2018). An ex vivo human tumour assay reveals distinct patterns of EGFR trafficking in squamous cell carcinoma correlating to therapeutic outcomes. Journal of Investigative Dermatology, 139 (1), 213-223. doi: 10.1016/j.jid.2018.06.190

An ex vivo human tumour assay reveals distinct patterns of EGFR trafficking in squamous cell carcinoma correlating to therapeutic outcomes

2018

Journal Article

Clinically-relevant rapamycin treatment regimens enhance CD8+ effector memory T cell function in the skin and allow their infiltration into cutaneous squamous cell carcinoma

Jung, Ji-Won, Veitch, Margaret, Bridge, Jennifer A., Overgaard, Nana H., Cruz, Jazmina L., Linedale, Richard, Franklin, Michael E., Saunders, Nicholas A., Simpson, Fiona, Frazer, Ian H., Steptoe, Raymond J. and Wells, James W. (2018). Clinically-relevant rapamycin treatment regimens enhance CD8+ effector memory T cell function in the skin and allow their infiltration into cutaneous squamous cell carcinoma. OncoImmunology, 7 (9) e1479627, 1-16. doi: 10.1080/2162402X.2018.1479627

Clinically-relevant rapamycin treatment regimens enhance CD8+ effector memory T cell function in the skin and allow their infiltration into cutaneous squamous cell carcinoma

2018

Journal Article

Detection of HPV E7 transcription at single-cell resolution in epidermis

Lukowski, S. W., Tuong, Z. K., Noske, K., Senabouth, A., Nguyen, Q. H., Andersen, S. B., Soyer, H. P., Frazer, I. H. and Powell, J. E. (2018). Detection of HPV E7 transcription at single-cell resolution in epidermis. The Journal of Investigative Dermatology, 138 (12), 2558-2567. doi: 10.1016/j.jid.2018.06.169

Detection of HPV E7 transcription at single-cell resolution in epidermis

2018

Journal Article

Safety, tolerability, acceptability and immunogenicity of an influenza vaccine delivered to human skin by a novel high-density microprojection array patch (Nanopatch™)

Fernando, Germain J. P., Hickling, Julian, Jayashi Flores, Cesar M., Griffin, Paul, Anderson, Christopher D., Skinner, S. Rachel, Davies, Cristyn, Witham, Katey, Pryor, Melinda, Bodle, Jesse, Rockman, Steve, Frazer, Ian H. and Forster, Angus H. (2018). Safety, tolerability, acceptability and immunogenicity of an influenza vaccine delivered to human skin by a novel high-density microprojection array patch (Nanopatch™). Vaccine, 36 (26), 3779-3788. doi: 10.1016/j.vaccine.2018.05.053

Safety, tolerability, acceptability and immunogenicity of an influenza vaccine delivered to human skin by a novel high-density microprojection array patch (Nanopatch™)

2018

Journal Article

HPV16E7 Induced Hyperplasia Promotes CXCL9/10 Expression and Induces CXCR3+ T cell Migration to Skin

Kuo, Paula, Tuong, Zewen K, Teoh, Siok Min, Frazer, Ian H, Mattarollo, Stephen and Leggatt, Graham R (2018). HPV16E7 Induced Hyperplasia Promotes CXCL9/10 Expression and Induces CXCR3+ T cell Migration to Skin. The Journal of investigative dermatology, 138 (6), 1348-1359. doi: 10.1016/j.jid.2017.12.021

HPV16E7 Induced Hyperplasia Promotes CXCL9/10 Expression and Induces CXCR3+ T cell Migration to Skin