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2024

Journal Article

Outstanding Reviewers for <i>RSC Chemical Biology</i> in 2023

Conibear, Anne C., Gersch, Malte, Holland, Jason, Jamieson, Andrew G., van Noort, Gerbrand van der Heden, Wagner, Gerd, Yuan, Lin, Zhu, Guangyu and Zou, Taotao (2024). Outstanding Reviewers for RSC Chemical Biology in 2023. Rsc Chemical Biology. doi: 10.1039/d4cb90038c

Outstanding Reviewers for <i>RSC Chemical Biology</i> in 2023

2024

Journal Article

Phosphorylation of the HMGN1 nucleosome binding domain decreases helicity and interactions with the acidic patch

Iebed, Dina, Gökler, Tobias, van Ingen, Hugo and Conibear, Anne Claire (2024). Phosphorylation of the HMGN1 nucleosome binding domain decreases helicity and interactions with the acidic patch. ChemBioChem. doi: 10.1002/cbic.202400589

Phosphorylation of the HMGN1 nucleosome binding domain decreases helicity and interactions with the acidic patch

2024

Journal Article

Tyrosine Sulfation Modulates the Binding Affinity of Chemokine-Targeting Nanobodies

Dilly, Joshua J., Morgan, Alexandra L., Bedding, Max J., Low, Jason K. K., Mackay, Joel P., Conibear, Anne C., Bhusal, Ram Prasad, Stone, Martin J., Franck, Charlotte and Payne, Richard J. (2024). Tyrosine Sulfation Modulates the Binding Affinity of Chemokine-Targeting Nanobodies. ACS Chemical Biology, 19 (7), 1426-1432. doi: 10.1021/acschembio.4c00230

Tyrosine Sulfation Modulates the Binding Affinity of Chemokine-Targeting Nanobodies

2024

Journal Article

Semisynthesis of segmentally isotope-labeled and site-specifically palmitoylated CD44 cytoplasmic tail

Vogl, Dominik P., Mateos, Borja, Migotti, Mario, Felkl, Manuel, Conibear, Anne C., Konrat, Robert and Becker, Christian F.W. (2024). Semisynthesis of segmentally isotope-labeled and site-specifically palmitoylated CD44 cytoplasmic tail. Bioorganic and Medicinal Chemistry, 100 117617, 117617. doi: 10.1016/j.bmc.2024.117617

Semisynthesis of segmentally isotope-labeled and site-specifically palmitoylated CD44 cytoplasmic tail

2023

Journal Article

Reflections on navigating a pandemic: perspectives from the chemical biology community

Conibear, Anne C. and Hartrampf, Nina (2023). Reflections on navigating a pandemic: perspectives from the chemical biology community. ChemBioChem, 24 (14) e202300258, 1-7. doi: 10.1002/cbic.202300258

Reflections on navigating a pandemic: perspectives from the chemical biology community

2023

Journal Article

Facilitating the structural characterisation of non-canonical amino acids in biomolecular NMR

Kuschert, Sarah, Stroet, Martin, Chin, Yanni Ka-Yan, Conibear, Anne Claire, Jia, Xinying, Lee, Thomas, Bartling, Christian Reinhard Otto, Strømgaard, Kristian, Güntert, Peter, Rosengren, Karl Johan, Mark, Alan Edward and Mobli, Mehdi (2023). Facilitating the structural characterisation of non-canonical amino acids in biomolecular NMR. Magnetic Resonance, 4 (1), 57-72. doi: 10.5194/mr-4-57-2023

Facilitating the structural characterisation of non-canonical amino acids in biomolecular NMR

2021

Journal Article

A conserved β‐bulge glycine residue facilitates folding and increases stability of the mouse α‐defensin cryptdin‐4

Clark, Richard J., Phan, Thanh Huyen, Song, Angela, Ouellette, André J., Conibear, Anne C. and Rosengren, K. Johan (2021). A conserved β‐bulge glycine residue facilitates folding and increases stability of the mouse α‐defensin cryptdin‐4. Peptide Science, 114 (1) e24250. doi: 10.1002/pep2.24250

A conserved β‐bulge glycine residue facilitates folding and increases stability of the mouse α‐defensin cryptdin‐4

2021

Journal Article

Segmental and site-specific isotope labelling strategies for structural analysis of posttranslationally modified proteins

Vogl, Dominik P., Conibear, Anne C. and Becker, Christian F. W. (2021). Segmental and site-specific isotope labelling strategies for structural analysis of posttranslationally modified proteins. RSC Chemical Biology, 2 (5), 1441-1461. doi: 10.1039/d1cb00045d

Segmental and site-specific isotope labelling strategies for structural analysis of posttranslationally modified proteins

2021

Journal Article

Posttranslational modifications of α-conotoxins: sulfotyrosine and C-terminal amidation stabilise structures and increase acetylcholine receptor binding

Ho, Thao N. T., Lee, Han Siean, Swaminathan, Shilpa, Goodwin, Lewis, Rai, Nishant, Ushay, Brianna, Lewis, Richard J., Rosengren, K. Johan and Conibear, Anne C. (2021). Posttranslational modifications of α-conotoxins: sulfotyrosine and C-terminal amidation stabilise structures and increase acetylcholine receptor binding. RSC Medicinal Chemistry, 12 (9), 1574-1584. doi: 10.1039/d1md00182e

Posttranslational modifications of α-conotoxins: sulfotyrosine and C-terminal amidation stabilise structures and increase acetylcholine receptor binding

2021

Journal Article

Site-specific modification and segmental isotope labelling of HMGN1 reveals long-range conformational perturbations caused by posttranslational modifications

Niederacher, Gerhard, Urwin, Debra, Dijkwel, Yasmin, Tremethick, David J., Rosengren, K. Johan, Becker, Christian F. W. and Conibear, Anne C. (2021). Site-specific modification and segmental isotope labelling of HMGN1 reveals long-range conformational perturbations caused by posttranslational modifications. RSC Chemical Biology, 2 (2), 537-550. doi: 10.1039/d0cb00175a

Site-specific modification and segmental isotope labelling of HMGN1 reveals long-range conformational perturbations caused by posttranslational modifications

2020

Journal Article

Deciphering protein post-translational modifications using chemical biology tools

Conibear, Anne C. (2020). Deciphering protein post-translational modifications using chemical biology tools. Nature Reviews Chemistry, 4 (12), 674-695. doi: 10.1038/s41570-020-00223-8

Deciphering protein post-translational modifications using chemical biology tools

2020

Journal Article

Synthesis and anti-parasitic activity of achiral N-benzylated phosphoramidic acid derivatives

Adeyemi, Christiana M., Conibear, Anne C., Mutorwa, Marius K., Nokalipa, Iviwe C., Isaacs, Michelle, Mnkandhla, Dumisani, Hoppe, Heinrich C., Lobb, Kevin A., Klein, Rosalyn and Kaye, Perry T. (2020). Synthesis and anti-parasitic activity of achiral N-benzylated phosphoramidic acid derivatives. Bioorganic Chemistry, 101 103947, 103947. doi: 10.1016/j.bioorg.2020.103947

Synthesis and anti-parasitic activity of achiral N-benzylated phosphoramidic acid derivatives

2019

Journal Article

Random coil shifts of posttranslationally modified amino acids

Conibear, Anne C., Rosengren, K. Johan, Becker, Christian F. W. and Kaehlig, Hanspeter (2019). Random coil shifts of posttranslationally modified amino acids. Journal of Biomolecular NMR, 73 (10-11), 587-599. doi: 10.1007/s10858-019-00270-4

Random coil shifts of posttranslationally modified amino acids

2019

Journal Article

Tumor-targeting immune system engagers (ISErs) activate human neutrophils after binding to cancer cells

Pötgens, André J. G., Conibear, Anne C., Altdorf, Claudia, Hilzendeger, Clarissa and Becker, Christian F. W. (2019). Tumor-targeting immune system engagers (ISErs) activate human neutrophils after binding to cancer cells. Biochemistry, 58 (22) acs.biochem.9b00169, 2642-2652. doi: 10.1021/acs.biochem.9b00169

Tumor-targeting immune system engagers (ISErs) activate human neutrophils after binding to cancer cells

2019

Journal Article

Multifunctional scaffolds for assembling cancer-targeting immune stimulators using chemoselective ligations

Conibear, Anne C., Thewes, Karine, Groysbeck, Nadja and Becker, Christian F.W. (2019). Multifunctional scaffolds for assembling cancer-targeting immune stimulators using chemoselective ligations. Frontiers in Chemistry, 7 (MAR) 113, 113. doi: 10.3389/fchem.2019.00113

Multifunctional scaffolds for assembling cancer-targeting immune stimulators using chemoselective ligations

2019

Conference Publication

Protein Chemistry Looking Ahead: 8th Chemical Protein Synthesis Meeting 16-19 June 2019, Berlin, Germany

Bello, Claudia, Hartrampf, Nina, Walport, Louise J. and Conibear, Anne C. (2019). Protein Chemistry Looking Ahead: 8th Chemical Protein Synthesis Meeting 16-19 June 2019, Berlin, Germany. 8th Chemical Protein Synthesis, Berlin, Germany, 16-19 June 2019. Cambridge, MA, United States: Cell Press. doi: 10.1016/j.chembiol.2019.09.011

Protein Chemistry Looking Ahead: 8th Chemical Protein Synthesis Meeting 16-19 June 2019, Berlin, Germany

2018

Journal Article

Native chemical ligation in protein synthesis and semi-synthesis

Conibear, Anne C., Watson, Emma E., Payne, Richard J. and Becker, Christian F. W. (2018). Native chemical ligation in protein synthesis and semi-synthesis. Chemical Society Reviews, 47 (24), 9046-9068. doi: 10.1039/c8cs00573g

Native chemical ligation in protein synthesis and semi-synthesis

2018

Conference Publication

Advancing the frontiers of chemical protein synthesis - the 7CPS meeting, Haifa, Israel

Conibear, Anne C. and Muttenthaler, Markus (2018). Advancing the frontiers of chemical protein synthesis - the 7CPS meeting, Haifa, Israel. Cambridge, MA, United States: Cell Press. doi: 10.1016/j.chembiol.2018.03.001

Advancing the frontiers of chemical protein synthesis - the 7CPS meeting, Haifa, Israel

2018

Journal Article

Synthetic cancer-targeting innate immune stimulators give insights into avidity effects

Conibear, Anne C., Poetgens, Andre J. G., Thewes, Karine, Altdorf, Claudia, Hilzendeger, Clarissa and Becker, Christian F. W. (2018). Synthetic cancer-targeting innate immune stimulators give insights into avidity effects. ChemBioChem, 19 (5), 459-469. doi: 10.1002/cbic.201700522

Synthetic cancer-targeting innate immune stimulators give insights into avidity effects

2017

Journal Article

Synthetic integrin-binding immune stimulators target cancer cells and prevent tumor formation

Brehs, Manuel, Poetgens, Andre J. G., Steitz, Julia, Thewes, Karine, Schwarz, Janett, Conibear, Anne C., Bartneck, Matthias, Tacke, Frank and Becker, Christian F. W. (2017). Synthetic integrin-binding immune stimulators target cancer cells and prevent tumor formation. Scientific Reports, 7 (1) 17592, 17592. doi: 10.1038/s41598-017-17627-0

Synthetic integrin-binding immune stimulators target cancer cells and prevent tumor formation