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2024 Journal Article Tyrosine Sulfation Modulates the Binding Affinity of Chemokine-Targeting NanobodiesDilly, Joshua J., Morgan, Alexandra L., Bedding, Max J., Low, Jason K. K., Mackay, Joel P., Conibear, Anne C., Bhusal, Ram Prasad, Stone, Martin J., Franck, Charlotte and Payne, Richard J. (2024). Tyrosine Sulfation Modulates the Binding Affinity of Chemokine-Targeting Nanobodies. ACS Chemical Biology, 19 (7), 1426-1432. doi: 10.1021/acschembio.4c00230 |
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2024 Journal Article Semisynthesis of segmentally isotope-labeled and site-specifically palmitoylated CD44 cytoplasmic tailVogl, Dominik P., Mateos, Borja, Migotti, Mario, Felkl, Manuel, Conibear, Anne C., Konrat, Robert and Becker, Christian F.W. (2024). Semisynthesis of segmentally isotope-labeled and site-specifically palmitoylated CD44 cytoplasmic tail. Bioorganic and Medicinal Chemistry, 100 117617, 117617. doi: 10.1016/j.bmc.2024.117617 |
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2023 Journal Article Reflections on navigating a pandemic: perspectives from the chemical biology communityConibear, Anne C. and Hartrampf, Nina (2023). Reflections on navigating a pandemic: perspectives from the chemical biology community. ChemBioChem, 24 (14) e202300258, 1-7. doi: 10.1002/cbic.202300258 |
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2023 Journal Article Facilitating the structural characterisation of non-canonical amino acids in biomolecular NMRKuschert, Sarah, Stroet, Martin, Chin, Yanni Ka-Yan, Conibear, Anne Claire, Jia, Xinying, Lee, Thomas, Bartling, Christian Reinhard Otto, Strømgaard, Kristian, Güntert, Peter, Rosengren, Karl Johan, Mark, Alan Edward and Mobli, Mehdi (2023). Facilitating the structural characterisation of non-canonical amino acids in biomolecular NMR. Magnetic Resonance, 4 (1), 57-72. doi: 10.5194/mr-4-57-2023 |
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2021 Journal Article A conserved β‐bulge glycine residue facilitates folding and increases stability of the mouse α‐defensin cryptdin‐4Clark, Richard J., Phan, Thanh Huyen, Song, Angela, Ouellette, André J., Conibear, Anne C. and Rosengren, K. Johan (2021). A conserved β‐bulge glycine residue facilitates folding and increases stability of the mouse α‐defensin cryptdin‐4. Peptide Science, 114 (1) e24250. doi: 10.1002/pep2.24250 |
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2021 Journal Article Segmental and site-specific isotope labelling strategies for structural analysis of posttranslationally modified proteinsVogl, Dominik P., Conibear, Anne C. and Becker, Christian F. W. (2021). Segmental and site-specific isotope labelling strategies for structural analysis of posttranslationally modified proteins. RSC Chemical Biology, 2 (5), 1441-1461. doi: 10.1039/d1cb00045d |
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2021 Journal Article Site-specific modification and segmental isotope labelling of HMGN1 reveals long-range conformational perturbations caused by posttranslational modificationsNiederacher, Gerhard, Urwin, Debra, Dijkwel, Yasmin, Tremethick, David J., Rosengren, K. Johan, Becker, Christian F. W. and Conibear, Anne C. (2021). Site-specific modification and segmental isotope labelling of HMGN1 reveals long-range conformational perturbations caused by posttranslational modifications. RSC Chemical Biology, 2 (2), 537-550. doi: 10.1039/d0cb00175a |
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2021 Journal Article Posttranslational modifications of α-conotoxins: sulfotyrosine and C-terminal amidation stabilise structures and increase acetylcholine receptor bindingHo, Thao N. T., Lee, Han Siean, Swaminathan, Shilpa, Goodwin, Lewis, Rai, Nishant, Ushay, Brianna, Lewis, Richard J., Rosengren, K. Johan and Conibear, Anne C. (2021). Posttranslational modifications of α-conotoxins: sulfotyrosine and C-terminal amidation stabilise structures and increase acetylcholine receptor binding. RSC Medicinal Chemistry, 12 (9), 1574-1584. doi: 10.1039/d1md00182e |
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2020 Journal Article Deciphering protein post-translational modifications using chemical biology toolsConibear, Anne C. (2020). Deciphering protein post-translational modifications using chemical biology tools. Nature Reviews Chemistry, 4 (12), 674-695. doi: 10.1038/s41570-020-00223-8 |
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2020 Journal Article Synthesis and anti-parasitic activity of achiral N-benzylated phosphoramidic acid derivativesAdeyemi, Christiana M., Conibear, Anne C., Mutorwa, Marius K., Nokalipa, Iviwe C., Isaacs, Michelle, Mnkandhla, Dumisani, Hoppe, Heinrich C., Lobb, Kevin A., Klein, Rosalyn and Kaye, Perry T. (2020). Synthesis and anti-parasitic activity of achiral N-benzylated phosphoramidic acid derivatives. Bioorganic Chemistry, 101 103947, 103947. doi: 10.1016/j.bioorg.2020.103947 |
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2019 Journal Article Random coil shifts of posttranslationally modified amino acidsConibear, Anne C., Rosengren, K. Johan, Becker, Christian F. W. and Kaehlig, Hanspeter (2019). Random coil shifts of posttranslationally modified amino acids. Journal of Biomolecular NMR, 73 (10-11), 587-599. doi: 10.1007/s10858-019-00270-4 |
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2019 Journal Article Tumor-targeting immune system engagers (ISErs) activate human neutrophils after binding to cancer cellsPötgens, André J. G., Conibear, Anne C., Altdorf, Claudia, Hilzendeger, Clarissa and Becker, Christian F. W. (2019). Tumor-targeting immune system engagers (ISErs) activate human neutrophils after binding to cancer cells. Biochemistry, 58 (22) acs.biochem.9b00169, 2642-2652. doi: 10.1021/acs.biochem.9b00169 |
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2019 Journal Article Multifunctional scaffolds for assembling cancer-targeting immune stimulators using chemoselective ligationsConibear, Anne C., Thewes, Karine, Groysbeck, Nadja and Becker, Christian F.W. (2019). Multifunctional scaffolds for assembling cancer-targeting immune stimulators using chemoselective ligations. Frontiers in Chemistry, 7 (MAR) 113, 113. doi: 10.3389/fchem.2019.00113 |
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2018 Journal Article Native chemical ligation in protein synthesis and semi-synthesisConibear, Anne C., Watson, Emma E., Payne, Richard J. and Becker, Christian F. W. (2018). Native chemical ligation in protein synthesis and semi-synthesis. Chemical Society Reviews, 47 (24), 9046-9068. doi: 10.1039/c8cs00573g |
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2018 Journal Article Synthetic cancer-targeting innate immune stimulators give insights into avidity effectsConibear, Anne C., Poetgens, Andre J. G., Thewes, Karine, Altdorf, Claudia, Hilzendeger, Clarissa and Becker, Christian F. W. (2018). Synthetic cancer-targeting innate immune stimulators give insights into avidity effects. ChemBioChem, 19 (5), 459-469. doi: 10.1002/cbic.201700522 |
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2017 Journal Article Synthetic integrin-binding immune stimulators target cancer cells and prevent tumor formationBrehs, Manuel, Poetgens, Andre J. G., Steitz, Julia, Thewes, Karine, Schwarz, Janett, Conibear, Anne C., Bartneck, Matthias, Tacke, Frank and Becker, Christian F. W. (2017). Synthetic integrin-binding immune stimulators target cancer cells and prevent tumor formation. Scientific Reports, 7 (1) 17592, 17592. doi: 10.1038/s41598-017-17627-0 |
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2017 Journal Article A comparative study of synthetic and semisynthetic approaches for ligating the epidermal growth factor to a bivalent scaffoldGell, Anna Lena, Groysbeck, Nadja, Becker, Christian F. W. and Conibear, Anne C. (2017). A comparative study of synthetic and semisynthetic approaches for ligating the epidermal growth factor to a bivalent scaffold. Journal of Peptide Science, 23 (12), 871-879. doi: 10.1002/psc.3051 |
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2017 Journal Article Recent Advances in Peptide-Based Approaches for Cancer TreatmentConibear, Anne C., Schmid, Alanca, Kamalov, Meder, Becker, Christian F. W. and Bello, Claudia (2017). Recent Advances in Peptide-Based Approaches for Cancer Treatment. Current Medicinal Chemistry, 27 (8), 1174-1205. doi: 10.2174/0929867325666171123204851 |
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2017 Journal Article Multifunctional alpha(v)beta(6) integrin-specific peptide-Pt(IV) conjugates for cancer cell targetingConibear, Anne C., Hager, Sonja, Mayr, Josef, Klose, Matthias H. M., Keppler, Bernhard K., Kowol, Christian R., Heffeter, Petra and Becker, Christian F. W. (2017). Multifunctional alpha(v)beta(6) integrin-specific peptide-Pt(IV) conjugates for cancer cell targeting. Bioconjugate Chemistry, 28 (9), 2429-2439. doi: 10.1021/acs.bioconjchem.7b00421 |
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2016 Journal Article Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptideKwon, Soohyun, Bosmans, Frank, Kaas, Quentin, Cheneval, Olivier, Conibear, Anne C., Rosengren, K. Johan, Wang, Conan K., Schroeder, Christina I. and Craik, David J. (2016). Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide. Biotechnology and Bioengineering, 113 (10), 2202-2212. doi: 10.1002/bit.25993 |
