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2017

Journal Article

Multifunctional alpha(v)beta(6) integrin-specific peptide-Pt(IV) conjugates for cancer cell targeting

Conibear, Anne C., Hager, Sonja, Mayr, Josef, Klose, Matthias H. M., Keppler, Bernhard K., Kowol, Christian R., Heffeter, Petra and Becker, Christian F. W. (2017). Multifunctional alpha(v)beta(6) integrin-specific peptide-Pt(IV) conjugates for cancer cell targeting. Bioconjugate Chemistry, 28 (9), 2429-2439. doi: 10.1021/acs.bioconjchem.7b00421

Multifunctional alpha(v)beta(6) integrin-specific peptide-Pt(IV) conjugates for cancer cell targeting

2016

Journal Article

Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide

Kwon, Soohyun, Bosmans, Frank, Kaas, Quentin, Cheneval, Olivier, Conibear, Anne C., Rosengren, K. Johan, Wang, Conan K., Schroeder, Christina I. and Craik, David J. (2016). Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide. Biotechnology and Bioengineering, 113 (10), 2202-2212. doi: 10.1002/bit.25993

Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide

2016

Journal Article

Arginine side-chain modification that occurs during copper-catalysed azide-alkyne click reactions resembles an advanced glycation end product

Conibear, Anne C., Farbiarz, Karine, Mayer, Rupert L., Matveenko, Maria, Kaehlig, Hanspeter and Becker, Christian F. W. (2016). Arginine side-chain modification that occurs during copper-catalysed azide-alkyne click reactions resembles an advanced glycation end product. Organic and Biomolecular Chemistry, 14 (26), 6205-6211. doi: 10.1039/c6ob00932h

Arginine side-chain modification that occurs during copper-catalysed azide-alkyne click reactions resembles an advanced glycation end product

2016

Journal Article

Mirror images of antimicrobial peptides provide reflections on their functions and amyloidogenic properties

Wang, Conan K., King, Gordon J., Conibear, Anne C., Ramos, Mariana C., Chaousis, Stephanie, Henriques, Sonia Troeira and Craik, David J. (2016). Mirror images of antimicrobial peptides provide reflections on their functions and amyloidogenic properties. Journal of American Chemical Society, 138 (17), 5706-5713. doi: 10.1021/jacs.6b02575

Mirror images of antimicrobial peptides provide reflections on their functions and amyloidogenic properties

2016

Journal Article

Approaches to the stabilization of bioactive epitopes by grafting and peptide cyclization

Conibear, Anne C., Chaousis, Stephanie, Durek, Thomas, Rosengren, K. Johan, Craik, David J. and Schroeder, Christina I. (2016). Approaches to the stabilization of bioactive epitopes by grafting and peptide cyclization. Biopolymers, 106 (1), 89-100. doi: 10.1002/bip.22767

Approaches to the stabilization of bioactive epitopes by grafting and peptide cyclization

2015

Journal Article

Transforming conotoxins into cyclotides: backbone cyclization of P-superfamily conotoxins

Akcan, Muharrem, Clark, Richard J., Daly, Norelle L., Conibear, Anne C., de Faoite, Andrew, Heghinian, Mari D., Sahil, Talwar, Adams, David J., Mari, Frank and Craik, David J. (2015). Transforming conotoxins into cyclotides: backbone cyclization of P-superfamily conotoxins. Peptide Science, 104 (6), 682-692. doi: 10.1002/bip.22699

Transforming conotoxins into cyclotides: backbone cyclization of P-superfamily conotoxins

2014

Journal Article

Insights into the molecular flexibility of theta-defensins by NMR relaxation analysis

Conibear, Anne C., Wang, Conan K., Bi, Tao, Rosengren, K. Johan, Camarero, Julio A. and Craik, David J. (2014). Insights into the molecular flexibility of theta-defensins by NMR relaxation analysis. Journal of Physical Chemistry B, 118 (49), 14257-14266. doi: 10.1021/jp507754c

Insights into the molecular flexibility of theta-defensins by NMR relaxation analysis

2014

Journal Article

The chemistry and biology of theta defensins

Conibear, Anne C. and Craik, David J. (2014). The chemistry and biology of theta defensins. Angewandte Chemie International Edition, 53 (40), 10612-10623. doi: 10.1002/anie.201402167

The chemistry and biology of theta defensins

2014

Journal Article

Chemie und Biologie von Theta-Defensinen

Conibear, Anne C. and Craik, David J. (2014). Chemie und Biologie von Theta-Defensinen. Angewandte Chemie, 126 (40), 10786-10798. doi: 10.1002/ange.201402167

Chemie und Biologie von Theta-Defensinen

2014

Journal Article

The cyclic cystine ladder of theta-defensins as a stable, bifunctional scaffold: a proof-of-concept study using the integrin-binding RGD motif

Conibear, Anne C., Bochen, Alexander, Rosengren, K. Johan, Stupar, Petar, Wang, Conan, Kessler, Horst and Craik, David J. (2014). The cyclic cystine ladder of theta-defensins as a stable, bifunctional scaffold: a proof-of-concept study using the integrin-binding RGD motif. ChemBioChem, 15 (3), 451-459. doi: 10.1002/cbic.201300568

The cyclic cystine ladder of theta-defensins as a stable, bifunctional scaffold: a proof-of-concept study using the integrin-binding RGD motif

2013

Journal Article

Exploring DOXP-reductoisomerase binding limits using phosphonated N-aryl and N-heteroarylcarboxamides as DXR inhibitors

Bodill, Taryn, Conibear, Anne C., Mutorwa, Marius K. M., Goble, Jessica L., Blatch, Gregory L., Lobb, Kevin A., Klein, Rosalyn and Kaye, Perry T. (2013). Exploring DOXP-reductoisomerase binding limits using phosphonated N-aryl and N-heteroarylcarboxamides as DXR inhibitors. Bioorganic and Medicinal Chemistry, 21 (14), 4332-4341. doi: 10.1016/j.bmc.2013.04.076

Exploring DOXP-reductoisomerase binding limits using phosphonated N-aryl and N-heteroarylcarboxamides as DXR inhibitors

2013

Journal Article

The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity

Conibear, Anne C., Rosengren, K. Johan, Daly, Norelle L., Henriques, Sonia Troeira and Craik, David J. (2013). The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity. Journal of Biological Chemistry, 288 (15), 10830-10840. doi: 10.1074/jbc.M113.451047

The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity

2012

Journal Article

Structural characterization of the cyclic cystine ladder motif of θ-defensins

Conibear, Anne C., Rosengren, K. Johan, Harvey, Peta J. and Craik, David J. (2012). Structural characterization of the cyclic cystine ladder motif of θ-defensins. Biochemistry, 51 (48), 9718-9726. doi: 10.1021/bi301363a

Structural characterization of the cyclic cystine ladder motif of θ-defensins

2012

Journal Article

Quantification of small cyclic disulfide-rich peptides

Conibear, Anne, Daly, Norelle L. and Craik, David J. (2012). Quantification of small cyclic disulfide-rich peptides. Biopolymers, 98 (6), 518-524. doi: 10.1002/bip.22121

Quantification of small cyclic disulfide-rich peptides

2011

Journal Article

Chemical Synthesis of Naturally-Occurring Cyclic Mini-Proteins from Plants and Animals

Conibear, Anne C. and Craik, David J. (2011). Chemical Synthesis of Naturally-Occurring Cyclic Mini-Proteins from Plants and Animals. Israel Journal of Chemistry, 51 (8-9), 908-916. doi: 10.1002/ijch.201100067

Chemical Synthesis of Naturally-Occurring Cyclic Mini-Proteins from Plants and Animals

2011

Journal Article

The chemistry of cyclotides

Craik, David J. and Conibear, Anne C. (2011). The chemistry of cyclotides. Journal of Organic Chemistry, 76 (12), 4805-4817. doi: 10.1021/jo200520v

The chemistry of cyclotides

2011

Journal Article

Synthesis and evaluation of phosphonated N-heteroarylcarboxamides as DOXP-reductoisomerase (DXR) inhibitors

Bodin, Taryn, Conibear, Anne C., Blatch, Gregory L., Lobb, Kevin A. and Kaye, Perry T. (2011). Synthesis and evaluation of phosphonated N-heteroarylcarboxamides as DOXP-reductoisomerase (DXR) inhibitors. Bioorganic and Medicinal Chemistry, 19 (3), 1321-1327. doi: 10.1016/j.bmc.2010.11.062

Synthesis and evaluation of phosphonated N-heteroarylcarboxamides as DOXP-reductoisomerase (DXR) inhibitors

2010

Journal Article

P-31 NMR kinetic study of the tandem cleavage of phosphonate esters by bromotrimethylsilane

Conibear, Anne C., Lobb, Kevin A. and Kaye, Perry T. (2010). P-31 NMR kinetic study of the tandem cleavage of phosphonate esters by bromotrimethylsilane. Tetrahedron, 66 (43), 8446-8449. doi: 10.1016/j.tet.2010.08.058

P-31 NMR kinetic study of the tandem cleavage of phosphonate esters by bromotrimethylsilane