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2025 Journal Article Amyotrophic lateral sclerosis established as a multistep process across phenotypesZiser, Laura, van Eijk, Ruben P. A., Kiernan, Matthew C., McRae, Allan, Henderson, Robert D., Schultz, David, Needham, Merrilee, Mathers, Susan, McCombe, Pam, Talman, Paul and Vucic, Steve (2025). Amyotrophic lateral sclerosis established as a multistep process across phenotypes. European Journal of Neurology, 32 (1) e16532. doi: 10.1111/ene.16532 |
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2024 Journal Article Liver‐specific deletion of de novo DNA methyltransferases protects against glucose intolerance in high‐fat diet‐fed male miceYao, S., Prates, K., Freydenzon, A., Assante, G., McRae, A. F., Morris, M. J. and Youngson, N. A. (2024). Liver‐specific deletion of de novo DNA methyltransferases protects against glucose intolerance in high‐fat diet‐fed male mice. The FASEB Journal, 38 (10) e23690, e23690. doi: 10.1096/fj.202301546rr |
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2024 Journal Article Genetic control of DNA methylation is largely shared across European and East Asian populationsHatton, Alesha A., Cheng, Fei-Fei, Lin, Tian, Shen, Ren-Juan, Chen, Jie, Zheng, Zhili, Qu, Jia, Lyu, Fan, Harris, Sarah E., Cox, Simon R., Jin, Zi-Bing, Martin, Nicholas G., Fan, Dongsheng, Montgomery, Grant W., Yang, Jian, Wray, Naomi R., Marioni, Riccardo E., Visscher, Peter M. and McRae, Allan F. (2024). Genetic control of DNA methylation is largely shared across European and East Asian populations. Nature Communications, 15 (1) 2713, 1-12. doi: 10.1038/s41467-024-47005-0 |
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2023 Journal Article The correlates of neonatal complement component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disordersBorbye-Lorenzen, Nis, Zhu, Zhihong, Agerbo, Esben, Albiñana, Clara, Benros, Michael E., Bian, Beilei, Børglum, Anders D., Bulik, Cynthia M., Debost, Jean-Christophe Philippe Goldtsche, Grove, Jakob, Hougaard, David M., McRae, Allan F., Mors, Ole, Mortensen, Preben Bo, Musliner, Katherine L., Nordentoft, Merete, Petersen, Liselotte V., Privé, Florian, Sidorenko, Julia, Skogstrand, Kristin, Werge, Thomas, Wray, Naomi R., Vilhjálmsson, Bjarni J. and McGrath, John J. (2023). The correlates of neonatal complement component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders. Cell Genomics, 3 (12) 100457, 1-23. doi: 10.1016/j.xgen.2023.100457 |
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2023 Journal Article Integration of datasets for individual prediction of DNA methylation-based biomarkersMerzbacher, Charlotte, Ryan, Barry, Goldsborough, Thibaut, Hillary, Robert F., Campbell, Archie, Murphy, Lee, McIntosh, Andrew M., Liewald, David, Harris, Sarah E., McRae, Allan F., Cox, Simon R., Cannings, Timothy I., Vallejos, Catalina A., McCartney, Daniel L. and Marioni, Riccardo E. (2023). Integration of datasets for individual prediction of DNA methylation-based biomarkers. Genome Biology, 24 (1) 278. doi: 10.1186/s13059-023-03114-5 |
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2023 Journal Article Blood-based genome-wide DNA methylation correlations across body-fat- and adiposity-related biochemical traitsHatton, Alesha A., Hillary, Robert F., Bernabeu, Elena, McCartney, Daniel L., Marioni, Riccardo E. and McRae, Allan F. (2023). Blood-based genome-wide DNA methylation correlations across body-fat- and adiposity-related biochemical traits. The American Journal of Human Genetics, 110 (9), 1564-1573. doi: 10.1016/j.ajhg.2023.08.004 |
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2023 Journal Article Beyond the Global Brain Differences: Intra-individual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion CarriersBoen, Rune, Kaufmann, Tobias, van der Meer, Dennis, Frei, Oleksandr, Agartz, Ingrid, Ames, David, Andersson, Micael, Armstrong, Nicola J., Artiges, Eric, Atkins, Joshua R., Bauer, Jochen, Benedetti, Francesco, Boomsma, Dorret I., Brodaty, Henry, Brosch, Katharina, Buckner, Randy L., Cairns, Murray J., Calhoun, Vince, Caspers, Svenja, Cichon, Sven, Corvin, Aiden P., Facorro, Benedicto Crespo, Dannlowski, Udo, David, Friederike S., de Geus, Eco J.C., de Zubicaray, Greig I., Desrivières, Sylvane, Doherty, Joanne L., Donohoe, Gary ... Sonderby, Ida E. (2023). Beyond the Global Brain Differences: Intra-individual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers. Biological Psychiatry, 95 (2), 147-160. doi: 10.1016/j.biopsych.2023.08.018 |
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2023 Journal Article Global endometrial DNA methylation analysis reveals insights into mQTL regulation and associated endometriosis disease risk and endometrial functionMortlock, Sally, Houshdaran, Sahar, Kosti, Idit, Rahmioglu, Nilufer, Nezhat, Camran, Vitonis, Allison F., Andrews, Shan V., Grosjean, Parker, Paranjpe, Manish, Horne, Andrew W., Jacoby, Alison, Lager, Jeannette, Opoku-Anane, Jessica, Vo, Kim Chi, Manvelyan, Evelina, Sen, Sushmita, Ghukasyan, Zhanna, Collins, Frances, Santamaria, Xavier, Saunders, Philippa, Kober, Kord, McRae, Allan F., Terry, Kathryn L., Vallvé-Juanico, Júlia, Becker, Christian, Rogers, Peter A. W., Irwin, Juan C., Zondervan, Krina, Montgomery, Grant W. ... Giudice, Linda (2023). Global endometrial DNA methylation analysis reveals insights into mQTL regulation and associated endometriosis disease risk and endometrial function. Communications Biology, 6 (1) 780, 1-17. doi: 10.1038/s42003-023-05070-z |
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2023 Journal Article Rare genetic variants underlie outlying levels of DNA methylation and gene-expressionChundru, V. Kartik, Marioni, Riccardo E., Pendergast, James G. D., Lin, Tian, Beveridge, Allan J., Martin, Nicholas G, Montgomery, Grant W., Hume, David A., Deary, Ian J., Visscher, Peter M., Wray, Naomi R. and McRae, Allan F. (2023). Rare genetic variants underlie outlying levels of DNA methylation and gene-expression. Human Molecular Genetics, 32 (11), 1912-1921. doi: 10.1093/hmg/ddad028 |
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2023 Journal Article An overview of DNA methylation-derived trait score methods and applicationsNabais, Marta F., Gadd, Danni A., Hannon, Eilis, Mill, Jonathan, McRae, Allan F. and Wray, Naomi R. (2023). An overview of DNA methylation-derived trait score methods and applications. Genome Biology, 24 (1) 28, 28. doi: 10.1186/s13059-023-02855-7 |
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2023 Journal Article Epigenome-wide association study reveals CpG sites associated with thyroid function and regulatory effects on KLF9Weihs, Antoine, Chaker, Layal, Martin, Tiphaine Christiane, Braun, Kim V.E., Campbell, Purdey J, Cox, Simon R, Fornage, Myriam, Gieger, Christian, Grabe, Hans J, Grallert, Harald, Harris, Sarah E, Kühnel, Brigitte, Marioni, Riccardo E, Martin, Nicholas G, McCartney, Daniel L, McRae, Allan F, Meisinger, Christa, Meurs, Joyce van, Nano, Jana, Nauck, Matthias, Peters, Annette, Prokisch, Holger, Roden, Michael, Selvin, Elizabeth, Beekman, Marian, van Heemst, Diana, Slagboom, Eline P, Swenson, Brenton R, Tin, Adrienne ... Teumer, Alexander (2023). Epigenome-wide association study reveals CpG sites associated with thyroid function and regulatory effects on KLF9. Thyroid (ja), 301-311. doi: 10.1089/thy.2022.0373 |
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2023 Journal Article Genotype by sex interactions in ankylosing spondylitisLi, Zhixiu, McRae, Allan F., Wang, Geng, Ellis, Jonathan J., Whyte, Jessica, Kenna, Tony J., Brown, Matthew A. and Evans, David M. (2023). Genotype by sex interactions in ankylosing spondylitis. Nature Genetics, 55 (1), 14-16. doi: 10.1038/s41588-022-01250-5 |
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2022 Journal Article Identification of influential probe types in epigenetic predictions of human traits: implications for microarray designHillary, Robert F., McCartney, Daniel L., McRae, Allan F., Campbell, Archie, Walker, Rosie M., Hayward, Caroline, Horvath, Steve, Porteous, David J., Evans, Kathryn L. and Marioni, Riccardo E. (2022). Identification of influential probe types in epigenetic predictions of human traits: implications for microarray design. Clinical Epigenetics, 14 (1) 100, 100. doi: 10.1186/s13148-022-01320-9 |
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2022 Journal Article Association between DNA methylation variability and self-reported exposure to heavy metalsFreydenzon, Anna, Nabais, Marta F., Lin, Tian, Williams, Kelly L., Wallace, Leanne, Henders, Anjali K., Blair, Ian P., Wray, Naomi R., Pamphlett, Roger and McRae, Allan F. (2022). Association between DNA methylation variability and self-reported exposure to heavy metals. Scientific Reports, 12 (1) 10582, 1-9. doi: 10.1038/s41598-022-13892-w |
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2022 Journal Article The role of critical immune genes in brain disorders: insights from neuroimaging immunogeneticsBian, Beilei, Couvy-Duchesne, Baptiste, Wray, Naomi R. and McRae, Allan F. (2022). The role of critical immune genes in brain disorders: insights from neuroimaging immunogenetics. Brain Communications, 4 (2) fcac078, fcac078. doi: 10.1093/braincomms/fcac078 |
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2022 Journal Article Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALSHop, Paul J., Zwamborn, Ramona A.J., Hannon, Eilis, Shireby, Gemma L., Nabais, Marta F., Walker, Emma M., van Rheenen, Wouter, van Vugt, Joke J.F.A., Dekker, Annelot M., Westeneng, Henk-Jan, Tazelaar, Gijs H.P., van Eijk, Kristel R., Moisse, Matthieu, Baird, Denis, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Ticozzi, Nicola, Ratti, Antonia, Cooper-Knock, Jonathan, Morrison, Karen E., Shaw, Pamela J., Basak, A. Nazli, Chiò, Adriano, Calvo, Andrea, Moglia, Cristina, Canosa, Antonio, Brunetti, Maura, Grassano, Maurizio, Gotkine, Marc ... Brain MEND Consortium (2022). Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS. Science Translational Medicine, 14 (633) eabj0264, 1-15. doi: 10.1126/scitranslmed.abj0264 |
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2022 Journal Article Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biologyvan Rheenen, Wouter, van der Spek, Rick A. A., Bakker, Mark K., van Vugt, Joke J. F. A., Hop, Paul J., Zwamborn, Ramona A. J., de Klein, Niek, Westra, Harm-Jan, Bakker, Olivier B., Deelen, Patrick, Shireby, Gemma, Hannon, Eilis, Moisse, Matthieu, Baird, Denis, Restuadi, Restuadi, Dolzhenko, Egor, Dekker, Annelot M., Gawor, Klara, Westeneng, Henk-Jan, Tazelaar, Gijs H. P., van Eijk, Kristel R., Kooyman, Maarten, Byrne, Ross P., Doherty, Mark, Heverin, Mark, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Ticozzi, Nicola ... SLAP Consortium (2022). Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nature Genetics, 54 (3), 361-361. doi: 10.1038/s41588-022-01020-3 |
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2022 Journal Article Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1Restuadi, Restuadi, Steyn, Frederik J., Kabashi, Edor, Ngo, Shyuan T., Cheng, Fei-Fei, Nabais, Marta F., Thompson, Mike J., Qi, Ting, Wu, Yang, Henders, Anjali K., Wallace, Leanne, Bye, Chris R., Turner, Bradley J., Ziser, Laura, Mathers, Susan, McCombe, Pamela A., Needham, Merrilee, Schultz, David, Kiernan, Matthew C., van Rheenen, Wouter, van den Berg, Leonard H., Veldink, Jan H., Ophoff, Roel, Gusev, Alexander, Zaitlen, Noah, McRae, Allan F., Henderson, Robert D., Wray, Naomi R., Giacomotto, Jean and Garton, Fleur C. (2022). Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1. Genome Medicine, 14 (1) 7, 7. doi: 10.1186/s13073-021-01006-6 |
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2022 Journal Article Epigenetic scores for the circulating proteome as tools for disease predictionGadd, Danni A., Hillary, Robert F., McCartney, Daniel L., Zaghlool, Shaza B., Stevenson, Anna J., Cheng, Yipeng, Fawns-Ritchie, Chloe, Nangle, Cliff, Campbell, Archie, Flaig, Robin, Harris, Sarah E., Walker, Rosie M., Shi, Liu, Tucker-Drob, Elliot M., Gieger, Christian, Peters, Annette, Waldenberger, Melanie, Graumann, Johannes, McRae, Allan F., Deary, Ian J., Porteous, David J., Hayward, Caroline, Visscher, Peter M., Cox, Simon R., Evans, Kathryn L., McIntosh, Andrew M., Suhre, Karsten and Marioni, Riccardo E. (2022). Epigenetic scores for the circulating proteome as tools for disease prediction. eLife, 11 e71802, 1-24. doi: 10.7554/eLife.71802 |
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2021 Journal Article Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biologyvan Rheenen, Wouter, van der Spek, Rick A. A., Bakker, Mark K., van Vugt, Joke J. F. A., Hop, Paul J., Zwamborn, Ramona A. J., de Klein, Niek, Westra, Harm-Jan, Bakker, Olivier B., Deelen, Patrick, Shireby, Gemma, Hannon, Eilis, Moisse, Matthieu, Baird, Denis, Restuadi, Restuadi, Dolzhenko, Egor, Dekker, Annelot M., Gawor, Klara, Westeneng, Henk-Jan, Tazelaar, Gijs H. P., van Eijk, Kristel R., Kooyman, Maarten, Byrne, Ross P., Doherty, Mark, Heverin, Mark, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Ticozzi, Nicola ... SLAP Consortium (2021). Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nature Genetics, 53 (12), 1636-1648. doi: 10.1038/s41588-021-00973-1 |
