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2017 Journal Article Short-course rapamycin treatment enables engraftment of immunogenic gene-engineered bone marrow under low-dose irradiation to permit long-term immunological toleranceBhatt, Kunal H., Rudraraju, Rajeev, Brooks, Jeremy F., Jung, Ji-Won, Galea, Ryan, Wells, James W. and Steptoe, Raymond J. (2017). Short-course rapamycin treatment enables engraftment of immunogenic gene-engineered bone marrow under low-dose irradiation to permit long-term immunological tolerance. Stem Cell Research and Therapy, 8 (1) 57, 57. doi: 10.1186/s13287-017-0508-3 |
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2017 Journal Article DNA vaccine encoding HPV16 oncogenes E6 and E7 induces potent cell-mediated and humoral immunity which protects in tumor challenge and drives E7-expressing skin graft rejectionChandra, Janin, Dutton, Julie L., Li, Bo, Woo, Wai-Ping, Xu, Yan, Tolley, Lynn K., Yong, Michelle, Wells, James W., Leggatt, Graham R., Finlayson, Neil and Frazer, Ian H. (2017). DNA vaccine encoding HPV16 oncogenes E6 and E7 induces potent cell-mediated and humoral immunity which protects in tumor challenge and drives E7-expressing skin graft rejection. Journal of Immunotherapy, 40 (2), 62-70. doi: 10.1097/CJI.0000000000000156 |
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2016 Journal Article Interaction between living bone particles and rhBMP-2 in large segmental defect healing in the rat femurLiu, Fangjun, Wells, James W., Porter, Ryan M., Glatt, Vaida, Shen, Zhenxin, Schinhan, Martina, Ivkovic, Alan, Vrahas, Mark S., Evans, Christopher H. and Ferreira, Elisabeth (2016). Interaction between living bone particles and rhBMP-2 in large segmental defect healing in the rat femur. Journal of Orthopaedic Research, 34 (12), 2137-2145. doi: 10.1002/jor.23255 |
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2016 Journal Article Assessing T-cell abundance in cutaneous squamous cell carcinoma: adding another string to your bowCruz, Jazmina L. and Wells, James W. (2016). Assessing T-cell abundance in cutaneous squamous cell carcinoma: adding another string to your bow. Experimental Dermatology, 25 (7), 507-508. doi: 10.1111/exd.13041 |
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2016 Journal Article Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejectionColeman, Miranda A., Jessup, Claire F., Bridge, Jennifer A., Overgaard, Nana H., Penko, Daniella, Walters, Stacey, Borg, Danielle J., Galea, Ryan, Forbes, Josephine M., Thomas, Ranjeny, Coates, Patrick T. C., Grey, Shane T., Wells, James W. and Steptoe, Raymond J. (2016). Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection. Diabetes, 65 (5), 1328-1340. doi: 10.2337/db15-1418 |
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2016 Journal Article Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccinesHussein, Waleed M., Liu, Tzu-Yu, Maruthayanar, Pirashanthini, Mukaida, Saori, Moyle, Peter M., Wells, James W., Toth, Istvan and Skwarczynski, Mariusz (2016). Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccines. Chemical Science, 7 (3), 2308-2321. doi: 10.1039/C5SC03859F |
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2015 Journal Article Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumorsMoyle, Peter M., Dai, Wei, Liu, Tzu-Yu, Hussein, Waleed M., Maruthayanar, Pirashanthini, Wells, James W., McMillan, Nigel A. J., Skwarczynski, Mariusz and Toth, Istvan (2015). Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumors. Bioorganic and Medicinal Chemistry Letters, 25 (23), 5570-5575. doi: 10.1016/j.bmcl.2015.10.049 |
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2015 Journal Article A High Through-put Platform for Recombinant Antibodies to Folded ProteinsHornsby, Michael, Paduch, Marcin, Miersch, Shane, Saeaef, Annika, Matsuguchi, Tet, Lee, Brian, Wypisniak, Karolina, Doak, Allison, King, Daniel, Usatyuk, Svitlana, Perry, Kimberly, Lu, Vince, Thomas, William, Luke, Judy, Goodman, Jay, Hoey, Robert J., Lai, Darson, Griffin, Carly, Li, Zhijian, Vizeacoumar, Franco J., Dong, Debbie, Campbell, Elliot, Anderson, Stephen, Zhong, Nan, Graeslund, Susanne, Koide, Shohei, Moffat, Jason, Sidhu, Sachdev, Kossiakoff, Anthony and Wells, James (2015). A High Through-put Platform for Recombinant Antibodies to Folded Proteins. Molecular & Cellular Proteomics, 14 (10), 2833-2847. doi: 10.1074/mcp.O115.052209 |
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2015 Journal Article Rapid and reliable healing of critical size bone defects with genetically modified sheep muscleLiu, F., Ferreira, E., Porter, R. M., Glatt, V., Schinhan, M., Shen, Z., Randolph, M. A., Kirker-Head, C. A., Wehling, C., Vrahas, M. S., Evans, C. H. and Wells, J. W. (2015). Rapid and reliable healing of critical size bone defects with genetically modified sheep muscle. European Cells and Materials, 30 (30), 118-131. doi: 10.22203/eCM.v030a09 |
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2015 Journal Article Impaired T-cell function in B-cell lymphoma: a direct consequence of events at the immunological synapse?Roufaiel, Marian Nassef Kadry Naguib, Wells, James W. and Steptoe, Raymond J. (2015). Impaired T-cell function in B-cell lymphoma: a direct consequence of events at the immunological synapse?. Frontiers in Immunology, 6 (JUN) 258, 258.1-258.10. doi: 10.3389/fimmu.2015.00258 |
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2015 Journal Article A novel zinc finger gene, ZNF465, is inappropriately expressed in acute myeloid leukaemia cellsCollin, Joseph F., Wells, James W., Czepulkowski, Barbara, Lyne, Linden, Duriez, Patrick J., Banham, Alison H., Mufti, Ghulam J. and Guinn, Barbara-ann (2015). A novel zinc finger gene, ZNF465, is inappropriately expressed in acute myeloid leukaemia cells. Genes Chromosomes Cancer, 54 (5), 288-302. doi: 10.1002/gcc.22242 |
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2015 Journal Article Does the nature of residual immune function explain the differential risk of non-melanoma skin cancer development in immunosuppressed organ transplant recipients?Jung, Ji-Won, Overgaard, Nana H., Burke, Michael T., Isbel, Nicole, Frazer, Ian H., Simpson, Fiona and Wells, James W. (2015). Does the nature of residual immune function explain the differential risk of non-melanoma skin cancer development in immunosuppressed organ transplant recipients?. International Journal of Cancer, 138 (2), 281-292. doi: 10.1002/ijc.29450 |
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2015 Journal Article HPV16 E7 expression in skin induces TSLP secretion, type 2 ILC infiltration and atopic dermatitis-like lesionsBergot, Anne-Sophie, Monnet, Nastasia, Tran, Son Le, Mittal, Deepak, Al-Kouba, Jane, Steptoe, Raymond J., Grimbaldeston, Michele A., Frazer, Ian H. and Wells, James W. (2015). HPV16 E7 expression in skin induces TSLP secretion, type 2 ILC infiltration and atopic dermatitis-like lesions. Immunology and Cell Biology, 93 (6), 540-547. doi: 10.1038/icb.2014.123 |
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2015 Journal Article CD4+/CD8+ double positive T cells: more than just a developmental stage?Overgaard, Nana H., Jung, Ji-Won, Steptoe, Raymond J. and Wells, James W. (2015). CD4+/CD8+ double positive T cells: more than just a developmental stage?. Journal of Leukocyte Biology, 97 (1), 31-38. doi: 10.1189/jlb.1RU0814-382 |
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2015 Journal Article Genetics and nonmelanoma skin cancer in kidney transplant recipientsBurke, Michael T., Isbel, Nicole, Barraclough, Katherine A., Jung, Ji-Won, Wells, James W. and Staatz, Christine E. (2015). Genetics and nonmelanoma skin cancer in kidney transplant recipients. Pharmacogenomics, 16 (2), 161-172. doi: 10.2217/pgs.14.156 |
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2014 Journal Article Comparative Immune Phenotypic Analysis of Cutaneous Squamous Cell Carcinoma and Intraepidermal Carcinoma in Immune-Competent Individuals: Proportional Representation of CD8+ T-Cells but Not FoxP3+ Regulatory T-Cells Is Associated with Disease StageFreeman, Andrew, Bridge, Jennifer A., Maruthayanar, Pirashanthini, Overgaard, Nana H., Jung, Ji-Won, Simpson, Fiona, Prow, Tarl W., Soyer, H. Peter, Frazer, Ian H., Freeman, Michael and Wells, James W. (2014). Comparative Immune Phenotypic Analysis of Cutaneous Squamous Cell Carcinoma and Intraepidermal Carcinoma in Immune-Competent Individuals: Proportional Representation of CD8+ T-Cells but Not FoxP3+ Regulatory T-Cells Is Associated with Disease Stage. PLoS One, 9 (10) e110928, e110928.1-e110928.9. doi: 10.1371/journal.pone.0110928 |
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2014 Journal Article HPV16-E7 expression in squamous epithelium creates a local immune suppressive environment via CCL2- and CCL5- mediated recruitment of mast cellsBergot, Anne-Sophie, Ford, Neill, Leggatt, Graham R., Wells, James W., Frazer, Ian H. and Grimbaldeston, Michele A. (2014). HPV16-E7 expression in squamous epithelium creates a local immune suppressive environment via CCL2- and CCL5- mediated recruitment of mast cells. PLoS Pathogens, 10 (10) e1004466, 1-11. doi: 10.1371/journal.ppat.1004466 |
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2013 Journal Article Inflammatory cytokines induce an unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrowFerreira, Elisabeth, Porter, Ryan M., Wehling, Nathalie, O'Sullivan, Regina P., Liu, Fangjun, Boskey, Adele, Estok, Daniel M., Harris, Mitchell B., Vrahas, Mark S., Evans, Christopher H. and Wells, James W. (2013). Inflammatory cytokines induce an unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrow. Journal of Biological Chemistry, 288 (41), 29494-29505. doi: 10.1074/jbc.M113.471268 |
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2013 Journal Article Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacyColeman, Miranda A., Bridge, Jennifer A., Lane, Steven W., Dixon, Chantelle M., Hill, Geoffrey R., Wells, James W., Thomas, Ranjeny and Steptoe, Raymond J. (2013). Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy. Blood, 121 (6), 1049-1058. doi: 10.1182/blood-2012-06-434100 |
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2013 Journal Article Arginase treatment prevents the recovery of canine lymphoma and osteosarcoma cells resistant to the toxic effects of prolonged arginine deprivationWells, James W., Evans, Christopher H., Scott, Milcah C., Ruetgen, Barbara C., O'Brien, Timothy D., Modiano, Jaime F., Cvetkovic, Goran and Tepic, Slobodan (2013). Arginase treatment prevents the recovery of canine lymphoma and osteosarcoma cells resistant to the toxic effects of prolonged arginine deprivation. PLoS One, 8 (1) e54464, e54464.1-e54464.9. doi: 10.1371/journal.pone.0054464 |
