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2024 Journal Article Utilizing murine dendritic cell line DC2.4 to evaluate the immunogenicity of subunit vaccines in vitroLu, Lantian, Kong, Wei Yang, Zhang, Jiahui, Firdaus, Farrhana, Wells, James W., Stephenson, Rachel J., Toth, Istvan, Skwarczynski, Mariusz and Cruz, Jazmina L. Gonzalez (2024). Utilizing murine dendritic cell line DC2.4 to evaluate the immunogenicity of subunit vaccines in vitro. Frontiers in Immunology, 15 ARTN 1298721, 1-13. doi: 10.3389/fimmu.2024.1298721 |
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2024 Journal Article Arginase-induced cell death pathways and metabolic changes in cancer cells are not altered by insulinChew, Hui Yi, Cvetkovic, Goran, Tepic, Slobodan and Wells, James W. (2024). Arginase-induced cell death pathways and metabolic changes in cancer cells are not altered by insulin. Scientific Reports, 14 (1) 4112. doi: 10.1038/s41598-024-54520-z |
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2024 Journal Article Predicting tacrolimus concentrations in the skin of adult kidney transplant recipients: a feasibility studySartain, Felicity, Viecelli, Andrea K., Veitch, Margaret, Franklin, Michael E., Dymock, Brian W., Wells, James W. and Campbell, Scott B. (2024). Predicting tacrolimus concentrations in the skin of adult kidney transplant recipients: a feasibility study. Transplant International, 37 12019. doi: 10.3389/ti.2024.12019 |
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2024 Journal Article Checkpoint kinase 1 inhibitor + low‐dose hydroxyurea efficiently kills BRAF inhibitor‐ and immune checkpoint inhibitor‐resistant melanomasZeng, Zhen, Ngo, Hung Long, Proctor, Martina, Rizos, Helen, Dolcetti, Riccardo, Cruz, Jazmina Gonzalez, Wells, James W. and Gabrielli, Brian (2024). Checkpoint kinase 1 inhibitor + low‐dose hydroxyurea efficiently kills BRAF inhibitor‐ and immune checkpoint inhibitor‐resistant melanomas. Pigment Cell and Melanoma Research, 37 (1), 45-50. doi: 10.1111/pcmr.13120 |
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2024 Journal Article Peritumoral administration of immunomodulatory antibodies as a triple combination suppresses skin tumor growth without systemic toxicityWright, Quentin G, Sinha, Debottam, Wells, James W, Frazer, Ian H, Gonzalez Cruz, Jazmina L and Leggatt, Graham Robert (2024). Peritumoral administration of immunomodulatory antibodies as a triple combination suppresses skin tumor growth without systemic toxicity. Journal for ImmunoTherapy of Cancer, 12 (1) e007960, e007960. doi: 10.1136/jitc-2023-007960 |
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2023 Journal Article Local blockade of tacrolimus promotes T-cell-mediated tumor regression in systemically immunosuppressed hostsVeitch, Margaret, Beaumont, Kimberly, Pouwer, Rebecca, Chew, Hui Yi, Frazer, Ian H., Soyer, H. Peter, Campbell, Scott, Dymock, Brian W., Harvey, Andrew, Cock, Terrie-Anne and Wells, James W. (2023). Local blockade of tacrolimus promotes T-cell-mediated tumor regression in systemically immunosuppressed hosts. Journal for ImmunoTherapy of Cancer, 11 (9) e006783, 1-15. doi: 10.1136/jitc-2023-006783 |
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2023 Journal Article Mono-phosphorylation at Ser4 of barrier-to-autointegration factor (Banf1) significantly reduces its DNA binding capability by inducing critical changes in its local conformation and DNA binding surfaceTang, Ming, Suraweera, Amila, Nie, Xuqiang, Li, Zilin, Lai, Pinglin, Wells, James W., O’Byrne, Kenneth J., Woods, Robert J, Bolderson, Emma and Richard, Derek J (2023). Mono-phosphorylation at Ser4 of barrier-to-autointegration factor (Banf1) significantly reduces its DNA binding capability by inducing critical changes in its local conformation and DNA binding surface. Physical Chemistry Chemical Physics, 25 (36), 24657-24677. doi: 10.1039/d3cp02302h |
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2023 Journal Article Enhanced hydrophobicity of CeO2 thin films: role of the morphology, adsorbed species and crystallographyMamedov, D., Asland, A. C., Cooil, S. P., Rost, H. I., Bakkelund, J., Allaniyazov, A., Wells, J. W. and Karazhanov, S. (2023). Enhanced hydrophobicity of CeO2 thin films: role of the morphology, adsorbed species and crystallography. Materials Today Communications, 35 106323, 1-8. doi: 10.1016/j.mtcomm.2023.106323 |
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2023 Journal Article Liposomal formulations of a polyleucine–antigen conjugate as therapeutic vaccines against cervical cancerFirdaus, Farrhana Z., Bartlett, Stacey, Hussein, Waleed M., Lu, Lantian, Wright, Quentin, Huang, Wenbin, Nahar, Ummey J., Yang, Jieru, Khongkow, Mattaka, Veitch, Margaret, Koirala, Prashamsa, Ruktanonchai, Uracha R., Monteiro, Michael J., Gonzalez Cruz, Jazmina L., Stephenson, Rachel J., Wells, James W., Toth, Istvan and Skwarczynski, Mariusz (2023). Liposomal formulations of a polyleucine–antigen conjugate as therapeutic vaccines against cervical cancer. Pharmaceutics, 15 (2) 602, 1-15. doi: 10.3390/pharmaceutics15020602 |
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2022 Journal Article Cytokine/Chemokine assessment as a complementary diagnostic tool for inflammatory skin diseasesLiu, Timothy J., Lin, Lynlee L., McMeniman, Erin, Wu, Jason, Kao, Yung-Ching, Kumari, Snehlata, Boyle, Glen M., Wells, James W., Soyer, H. Peter and Gonzalez-Cruz, Jazmina L. (2022). Cytokine/Chemokine assessment as a complementary diagnostic tool for inflammatory skin diseases. Frontiers in Immunology, 13 1028435, 1-8. doi: 10.3389/fimmu.2022.1028435 |
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2022 Journal Article Assessment of patient-to-patient and intra-individual human abdominal skin immune cell variabilityVeitch, Margaret, Layt, Craig, Raymond, Emma, Croaker, Andrew and Wells, James (2022). Assessment of patient-to-patient and intra-individual human abdominal skin immune cell variability. Archives of Medical Science, 18 (6), 1683-1688. doi: 10.5114/aoms/155183 |
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2022 Journal Article Prevalence of AAV2.5 neutralizing antibodies in synovial fluid and serum of patients with osteoarthritisAbdul, Temilola Y., Hawse, Gresin P., Smith, Jay, Sellon, Jacob L., Abdel, Matthew P., Wells, James W., Coenen, Michael J., Evans, Christopher H. and De La Vega, Rodolfo E. (2022). Prevalence of AAV2.5 neutralizing antibodies in synovial fluid and serum of patients with osteoarthritis. Gene Therapy, 30 (7-8), 1-5. doi: 10.1038/s41434-022-00326-5 |
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2021 Other Outputs Compound for prevention or treatment of a skin cancer or skin precancerWells, James, Dymock, Brian William, Harvey, Andrew, Cock, Terrie-Anne, Pouwer, Rebecca and Beaumont, Kimberley (2021). Compound for prevention or treatment of a skin cancer or skin precancer. WO2021248189. |
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2021 Journal Article Cellular responses at the application site of a high-density microarray patch delivering an influenza vaccine in a randomized, controlled phase I clinical trialDepelsenaire, Alexandra C. I., Witham, Katey, Veitch, Margaret, Wells, James W., Anderson, Christopher D., Lickliter, Jason D., Rockman, Steve, Bodle, Jesse, Treasure, Peter, Hickling, Julian, Fernando, Germain J. P. and Forster, Angus H. (2021). Cellular responses at the application site of a high-density microarray patch delivering an influenza vaccine in a randomized, controlled phase I clinical trial. PLoS One, 16 (7) e0255282, e0255282. doi: 10.1371/journal.pone.0255282 |
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2021 Journal Article Targeting Replication Stress Using CHK1 Inhibitor Promotes Innate and NKT Cell Immune Responses and Tumour RegressionProctor, Martina, Gonzalez Cruz, Jazmina L., Daignault-Mill, Sheena M., Veitch, Margaret, Zeng, Bijun, Ehmann, Anna, Sabdia, Muhammed, Snell, Cameron, Keane, Colm, Dolcetti, Riccardo, Haass, Nikolas K., Wells, James W. and Gabrielli, Brian (2021). Targeting Replication Stress Using CHK1 Inhibitor Promotes Innate and NKT Cell Immune Responses and Tumour Regression. Cancers, 13 (15) 3733, 1-19. doi: 10.3390/cancers13153733 |
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2021 Journal Article PD-1 and beyond to activate T cells in cutaneous squamous cell cancers: the case for 4-1BB and VISTA antibodies in combination therapyWright, Quentin, Gonzalez Cruz, Jazmina L., Wells, James W. and Leggatt, Graham R. (2021). PD-1 and beyond to activate T cells in cutaneous squamous cell cancers: the case for 4-1BB and VISTA antibodies in combination therapy. Cancers, 13 (13) 3310, 3310. doi: 10.3390/cancers13133310 |
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2021 Journal Article Evolution of cancer vaccines—challenges, achievements and future directionsTay, Ban Qi, Wright, Quentin, Ladwa, Rahul, Perry, Christopher, Leggatt, Graham, Simpson, Fiona, Wells, James W., Panizza, Benedict J., Frazer, Ian H. and Cruz, Jazmina L. G. (2021). Evolution of cancer vaccines—challenges, achievements and future directions. Vaccines, 9 (5) 535, 535. doi: 10.3390/vaccines9050535 |
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2021 Journal Article IFN-γ critically enables the intratumoural infiltration of CXCR3+ CD8+ T cells to drive squamous cell carcinoma regressionZeng, Zhen, Veitch, Margaret, Kelly, Gabrielle A., Tuong, Zewen K., Cruz, Jazmina G., Frazer, Ian H. and Wells, James W. (2021). IFN-γ critically enables the intratumoural infiltration of CXCR3+ CD8+ T cells to drive squamous cell carcinoma regression. Cancers, 13 (9) 2131, 2131. doi: 10.3390/cancers13092131 |
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2021 Journal Article Healing of sub-critical femoral osteotomies in mice is unaffected by tacrolimus and deletion of recombination activating gene 1Liu, T-Y, Bartnikowski, M., Wu, A. C., Veitch, M., Sokolowski, K. A., Millard, S. M., Pettit, A. R., Glatt, V., Evans, C. H. and Wells, J. W. (2021). Healing of sub-critical femoral osteotomies in mice is unaffected by tacrolimus and deletion of recombination activating gene 1. European Cells and Materials, 41, 345-354. doi: 10.22203/eCM.v041a22 |
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2021 Journal Article Investigating T cell immunity in cancer: achievements and prospectsZeng, Zhen, Chew, Hui Yi, Cruz, Jazmina G., Leggatt, Graham R. and Wells, James W. (2021). Investigating T cell immunity in cancer: achievements and prospects. International Journal of Molecular Sciences, 22 (6) 2907, 1-17. doi: 10.3390/ijms22062907 |
