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2018 Journal Article Clinically-relevant rapamycin treatment regimens enhance CD8+ effector memory T cell function in the skin and allow their infiltration into cutaneous squamous cell carcinomaJung, Ji-Won, Veitch, Margaret, Bridge, Jennifer A., Overgaard, Nana H., Cruz, Jazmina L., Linedale, Richard, Franklin, Michael E., Saunders, Nicholas A., Simpson, Fiona, Frazer, Ian H., Steptoe, Raymond J. and Wells, James W. (2018). Clinically-relevant rapamycin treatment regimens enhance CD8+ effector memory T cell function in the skin and allow their infiltration into cutaneous squamous cell carcinoma. OncoImmunology, 7 (9) e1479627, 1-16. doi: 10.1080/2162402X.2018.1479627 |
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2018 Journal Article Tetramer-based identification of naïve antigen-specific B cells within a polyclonal repertoireBrooks, Jeremy F., Liu, Xiao, Davies, Janet M., Wells, James W. and Steptoe, Raymond J. (2018). Tetramer-based identification of naïve antigen-specific B cells within a polyclonal repertoire. European Journal of Immunology, 48 (7), 1251-1254. doi: 10.1002/eji.201747447 |
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2018 Journal Article Characterization of 7A7, an anti-mouse EGFR monoclonal antibody proposed to be the mouse equivalent of cetuximabHe, Xuzhi, Cruz, Jazmina L., Joseph, Shannon, Pett, Nicola, Chew, Hui Yi, Tuong, Zewen K., Okano, Satomi, Kelly, Gabrielle, Veitch, Margaret, Simpson, Fiona and Wells, James W. (2018). Characterization of 7A7, an anti-mouse EGFR monoclonal antibody proposed to be the mouse equivalent of cetuximab. Oncotarget, 9 (15), 12250-12260. doi: 10.18632/oncotarget.24242 |
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2018 Conference Publication Dendritic cell-targeted self-antigen restrains autoreactive B cells by deletion and anergyBrooks, J., Davies, J., Wells, J. and Steptoe, R. (2018). Dendritic cell-targeted self-antigen restrains autoreactive B cells by deletion and anergy. 15th International Symposium on Dendritic Cells (DC), Aachen, Germany, 10-14 June 2018 . Weinheim, Germany: Wiley. |
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2017 Journal Article Re-educating immunity in respiratory allergies: the potential for hematopoietic stem cell-mediated gene therapyBrooks, Jeremy F, Davies, Janet M, Wells, James W and Steptoe, Raymond J (2017). Re-educating immunity in respiratory allergies: the potential for hematopoietic stem cell-mediated gene therapy. Journal of Molecular Medicine (Berlin, Germany), 96 (1), 21-30. doi: 10.1007/s00109-017-1611-8 |
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2017 Journal Article CD4+CD8β+ double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skinOvergaard, Nana H., Cruz, Jazmina L., Bridge, Jennifer A., Nel, Hendrik J., Frazer, Ian H., La Gruta, Nicole K., Blumenthal, Antje, Steptoe, Raymond J. and Wells, James W. (2017). CD4+CD8β+ double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin. Journal of Leukocyte Biology, 102 (3), 837-844. doi: 10.1189/jlb.1AB0217-065R |
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2017 Journal Article Overcoming resistance to targeted therapy with immunotherapy and combination therapy for metastatic melanomaKeller, Hilary R., Zhang, Xin, Li, Li, Schaider, Helmut and Wells, James W. (2017). Overcoming resistance to targeted therapy with immunotherapy and combination therapy for metastatic melanoma. Oncotarget, 8 (43), 75675-75686. doi: 10.18632/oncotarget.18523 |
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2017 Journal Article Sirolimus increases T-cell abundance in the sun exposed skin of kidney transplant recipientsBurke, Michael Thomas, Sambira Nahum, Lauren C., Isbel, Nicole M., Carroll, Robert P., Soyer, Hans Peter, Francis, Ross, Bridge, Jennifer Anne, Hawley, Carmel, Oliver, Kimberly, Staatz, Christine E. and Wells, James William (2017). Sirolimus increases T-cell abundance in the sun exposed skin of kidney transplant recipients. Transplantation Direct, 3 (7), e171. doi: 10.1097/TXD.0000000000000694 |
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2017 Journal Article Short-course rapamycin treatment enables engraftment of immunogenic gene-engineered bone marrow under low-dose irradiation to permit long-term immunological toleranceBhatt, Kunal H., Rudraraju, Rajeev, Brooks, Jeremy F., Jung, Ji-Won, Galea, Ryan, Wells, James W. and Steptoe, Raymond J. (2017). Short-course rapamycin treatment enables engraftment of immunogenic gene-engineered bone marrow under low-dose irradiation to permit long-term immunological tolerance. Stem Cell Research and Therapy, 8 (1) 57, 57. doi: 10.1186/s13287-017-0508-3 |
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2017 Journal Article DNA vaccine encoding HPV16 oncogenes E6 and E7 induces potent cell-mediated and humoral immunity which protects in tumor challenge and drives E7-expressing skin graft rejectionChandra, Janin, Dutton, Julie L., Li, Bo, Woo, Wai-Ping, Xu, Yan, Tolley, Lynn K., Yong, Michelle, Wells, James W., Leggatt, Graham R., Finlayson, Neil and Frazer, Ian H. (2017). DNA vaccine encoding HPV16 oncogenes E6 and E7 induces potent cell-mediated and humoral immunity which protects in tumor challenge and drives E7-expressing skin graft rejection. Journal of Immunotherapy, 40 (2), 62-70. doi: 10.1097/CJI.0000000000000156 |
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2016 Journal Article Interaction between living bone particles and rhBMP-2 in large segmental defect healing in the rat femurLiu, Fangjun, Wells, James W., Porter, Ryan M., Glatt, Vaida, Shen, Zhenxin, Schinhan, Martina, Ivkovic, Alan, Vrahas, Mark S., Evans, Christopher H. and Ferreira, Elisabeth (2016). Interaction between living bone particles and rhBMP-2 in large segmental defect healing in the rat femur. Journal of Orthopaedic Research, 34 (12), 2137-2145. doi: 10.1002/jor.23255 |
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2016 Conference Publication Preclinical modeling of EGFR-specific mAb and immune pathways that impact immunotherapics for squamous cell carcinomaHe, Xuzhi, Gonzalez Cruz, Jazmina , Simpson, Finoa and Wells, James (2016). Preclinical modeling of EGFR-specific mAb and immune pathways that impact immunotherapics for squamous cell carcinoma. Joint meeting of the Australasian Wound and Tissue Repair Society (AWTRS) and the Molecular & Experimental Pathology Society of Australasia (MEPSA), Melbourne, Australia, 7-9 November 2016. Hoboken, NJ, United States: Wiley-Blackwell. |
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2016 Journal Article Assessing T-cell abundance in cutaneous squamous cell carcinoma: adding another string to your bowCruz, Jazmina L. and Wells, James W. (2016). Assessing T-cell abundance in cutaneous squamous cell carcinoma: adding another string to your bow. Experimental Dermatology, 25 (7), 507-508. doi: 10.1111/exd.13041 |
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2016 Conference Publication Effects of Immunosuppression and Sun Exposure on Immune Cell Populations in Skin and Blood of Kidney Transplant Recipients.Burke, M., Nahum, L., Isbel, N., Carroll, R., Soyer, H., Francis, R., Bridge, J., Staatz, C. and Wells, J. (2016). Effects of Immunosuppression and Sun Exposure on Immune Cell Populations in Skin and Blood of Kidney Transplant Recipients.. American Transplant Congress, Boston Ma, Jun 11-15, 2016. HOBOKEN: WILEY-BLACKWELL. |
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2016 Journal Article Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejectionColeman, Miranda A., Jessup, Claire F., Bridge, Jennifer A., Overgaard, Nana H., Penko, Daniella, Walters, Stacey, Borg, Danielle J., Galea, Ryan, Forbes, Josephine M., Thomas, Ranjeny, Coates, Patrick T. C., Grey, Shane T., Wells, James W. and Steptoe, Raymond J. (2016). Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection. Diabetes, 65 (5), 1328-1340. doi: 10.2337/db15-1418 |
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2016 Journal Article Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccinesHussein, Waleed M., Liu, Tzu-Yu, Maruthayanar, Pirashanthini, Mukaida, Saori, Moyle, Peter M., Wells, James W., Toth, Istvan and Skwarczynski, Mariusz (2016). Double conjugation strategy to incorporate lipid adjuvants into multiantigenic vaccines. Chemical Science, 7 (3), 2308-2321. doi: 10.1039/C5SC03859F |
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2016 Book Chapter Regulation of CD8+ T cells in the skin and implications for the development of squamous cell carcinomaCruz, Jazmina L. and Wells, James W. (2016). Regulation of CD8+ T cells in the skin and implications for the development of squamous cell carcinoma. Horizons in cancer research. (pp. 119-145) edited by Hiroto S. Watanabe. New York, United States: Nova Science Publishers. |
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2016 Conference Publication Altering the balance between immune activation versus regulation in the skin to promote CD8 T-cell activity within epithelial cancersBridge, Jennifer A., Overgaard, Nana H., Steptoe, Raymond J., Frazer, Ian H. and Wells, James W. (2016). Altering the balance between immune activation versus regulation in the skin to promote CD8 T-cell activity within epithelial cancers. AACR 107th Annual Meeting on Bioinformatics and Systems Biology, New Orleans, La, United States, Apr 16-20, 2016. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2016-3999 |
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2016 Conference Publication Novel regulators of CD8(+) T-cell functions in the skinBridge, J. A., Overgaard, N. H., Cruz, J. L. G., Veitch, M., Frazer, I. H., Steptoe, R. J. and Wells, J. W. (2016). Novel regulators of CD8(+) T-cell functions in the skin. International Congress of Immunology (ICI), Melbourne, Australia, 21-16 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200 |
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2016 Conference Publication Rapamycin, but not tacrolimus, promotes Cd8 memory T-cell differentiation and function in the skinJung, Ji-Won, Simpson, Fiona, Frazer, Ian H. and Wells, James W. (2016). Rapamycin, but not tacrolimus, promotes Cd8 memory T-cell differentiation and function in the skin. Joint meeting of the Australasian Wound and Tissue Repair Society (AWTRS) and the Molecular & Experimental Pathology Society of Australasia (MEPSA), Melbourne Exhibition and Convention Centre, Melbourne, Australia, 7-9 November 2016. Hoboken, NJ United States: Wiley-Blackwell Publishing. |
