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2016

Conference Publication

Uncovering novel regulators of CD8(+) T-cell functions in the skin

Bridge, J. A., Overgaard, N. H., Cruz, J. L., Veitch, M., Frazer, I. H., Steptoe, R. J. and Wells, J. W. (2016). Uncovering novel regulators of CD8(+) T-cell functions in the skin. Asia-Pacific Combined Dermatology Research Conference, Noosa, Australia, 25–28 August 2016. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/ajd.12584

Uncovering novel regulators of CD8(+) T-cell functions in the skin

2016

Conference Publication

Ablation of pathogenic memory T-cell responses by bone marrow-mediated gene therapy under immune-preserving conditions

Steptoe, R., Al-Kouba, J., Coleman, M., Jessup, C., Starkey, M., Overgaard, N., Bridge, J., Horvat, J., Werder, R., Walters, S., Coates, P. T., Grey, S., Thomas, R., Wells, J., Hansbro, P., Phipps, S. and Davies, J. (2016). Ablation of pathogenic memory T-cell responses by bone marrow-mediated gene therapy under immune-preserving conditions. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley.

Ablation of pathogenic memory T-cell responses by bone marrow-mediated gene therapy under immune-preserving conditions

2016

Conference Publication

Preclinical modeling of EGFR-specific mAb and immune pathways that impact immunotherapics for squamous cell carcinoma

He, X., Cruz, Gonzalez J., Simpson, F. and Wells, J. (2016). Preclinical modeling of EGFR-specific mAb and immune pathways that impact immunotherapics for squamous cell carcinoma. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200

Preclinical modeling of EGFR-specific mAb and immune pathways that impact immunotherapics for squamous cell carcinoma

2016

Conference Publication

The impact of rapamycin and tacrolimus treatment on resident CD8+T-cell populations in cutaneous squamous cell carcinoma

Jung, Ji-Won, Taylor, Paul J., Simpson, Fiona, Frazer, Ian H. and Wells, James W. (2016). The impact of rapamycin and tacrolimus treatment on resident CD8+T-cell populations in cutaneous squamous cell carcinoma. International Cancer Immunotherapy Conference: Translating Science into Survival, New York, United States, September 16-19, 2015. Philadelphia, United States: American Association for Cancer Research. doi: 10.1158/2326-6074.CRICIMTEATIAACR15-B055

The impact of rapamycin and tacrolimus treatment on resident CD8+T-cell populations in cutaneous squamous cell carcinoma

2016

Conference Publication

Does dendritic-cell targeted antigen expression induce both T and B cell tolerance?

Brooks, J., Al-Kouba, J., Davies, J., Wells, J. and Steptoe, R. (2016). Does dendritic-cell targeted antigen expression induce both T and B cell tolerance?. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200

Does dendritic-cell targeted antigen expression induce both T and B cell tolerance?

2015

Journal Article

Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumors

Moyle, Peter M., Dai, Wei, Liu, Tzu-Yu, Hussein, Waleed M., Maruthayanar, Pirashanthini, Wells, James W., McMillan, Nigel A. J., Skwarczynski, Mariusz and Toth, Istvan (2015). Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumors. Bioorganic and Medicinal Chemistry Letters, 25 (23), 5570-5575. doi: 10.1016/j.bmcl.2015.10.049

Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumors

2015

Journal Article

A High Through-put Platform for Recombinant Antibodies to Folded Proteins

Hornsby, Michael, Paduch, Marcin, Miersch, Shane, Saeaef, Annika, Matsuguchi, Tet, Lee, Brian, Wypisniak, Karolina, Doak, Allison, King, Daniel, Usatyuk, Svitlana, Perry, Kimberly, Lu, Vince, Thomas, William, Luke, Judy, Goodman, Jay, Hoey, Robert J., Lai, Darson, Griffin, Carly, Li, Zhijian, Vizeacoumar, Franco J., Dong, Debbie, Campbell, Elliot, Anderson, Stephen, Zhong, Nan, Graeslund, Susanne, Koide, Shohei, Moffat, Jason, Sidhu, Sachdev, Kossiakoff, Anthony and Wells, James (2015). A High Through-put Platform for Recombinant Antibodies to Folded Proteins. Molecular & Cellular Proteomics, 14 (10), 2833-2847. doi: 10.1074/mcp.O115.052209

A High Through-put Platform for Recombinant Antibodies to Folded Proteins

2015

Journal Article

Rapid and reliable healing of critical size bone defects with genetically modified sheep muscle

Liu, F., Ferreira, E., Porter, R. M., Glatt, V., Schinhan, M., Shen, Z., Randolph, M. A., Kirker-Head, C. A., Wehling, C., Vrahas, M. S., Evans, C. H. and Wells, J. W. (2015). Rapid and reliable healing of critical size bone defects with genetically modified sheep muscle. European Cells and Materials, 30 (30), 118-131. doi: 10.22203/eCM.v030a09

Rapid and reliable healing of critical size bone defects with genetically modified sheep muscle

2015

Conference Publication

Reprogramming caspase activity by directed evolution provides alternate solutions for substrate recognition

MacPherson, Derek, Hill, Maureen, Wu, Peng, Julien, Olivier, Wells, James and Hardy, Jeanne (2015). Reprogramming caspase activity by directed evolution provides alternate solutions for substrate recognition. WASHINGTON: AMER CHEMICAL SOC.

Reprogramming caspase activity by directed evolution provides alternate solutions for substrate recognition

2015

Journal Article

Impaired T-cell function in B-cell lymphoma: a direct consequence of events at the immunological synapse?

Roufaiel, Marian Nassef Kadry Naguib, Wells, James W. and Steptoe, Raymond J. (2015). Impaired T-cell function in B-cell lymphoma: a direct consequence of events at the immunological synapse?. Frontiers in Immunology, 6 (JUN) 258, 258.1-258.10. doi: 10.3389/fimmu.2015.00258

Impaired T-cell function in B-cell lymphoma: a direct consequence of events at the immunological synapse?

2015

Journal Article

A novel zinc finger gene, ZNF465, is inappropriately expressed in acute myeloid leukaemia cells

Collin, Joseph F., Wells, James W., Czepulkowski, Barbara, Lyne, Linden, Duriez, Patrick J., Banham, Alison H., Mufti, Ghulam J. and Guinn, Barbara-ann (2015). A novel zinc finger gene, ZNF465, is inappropriately expressed in acute myeloid leukaemia cells. Genes Chromosomes Cancer, 54 (5), 288-302. doi: 10.1002/gcc.22242

A novel zinc finger gene, ZNF465, is inappropriately expressed in acute myeloid leukaemia cells

2015

Journal Article

Does the nature of residual immune function explain the differential risk of non-melanoma skin cancer development in immunosuppressed organ transplant recipients?

Jung, Ji-Won, Overgaard, Nana H., Burke, Michael T., Isbel, Nicole, Frazer, Ian H., Simpson, Fiona and Wells, James W. (2015). Does the nature of residual immune function explain the differential risk of non-melanoma skin cancer development in immunosuppressed organ transplant recipients?. International Journal of Cancer, 138 (2), 281-292. doi: 10.1002/ijc.29450

Does the nature of residual immune function explain the differential risk of non-melanoma skin cancer development in immunosuppressed organ transplant recipients?

2015

Journal Article

HPV16 E7 expression in skin induces TSLP secretion, type 2 ILC infiltration and atopic dermatitis-like lesions

Bergot, Anne-Sophie, Monnet, Nastasia, Tran, Son Le, Mittal, Deepak, Al-Kouba, Jane, Steptoe, Raymond J., Grimbaldeston, Michele A., Frazer, Ian H. and Wells, James W. (2015). HPV16 E7 expression in skin induces TSLP secretion, type 2 ILC infiltration and atopic dermatitis-like lesions. Immunology and Cell Biology, 93 (6), 540-547. doi: 10.1038/icb.2014.123

HPV16 E7 expression in skin induces TSLP secretion, type 2 ILC infiltration and atopic dermatitis-like lesions

2015

Book Chapter

Do actinic keratoses and superficial squamous cell carcinomas have a specific immunoprofile?

Wells, James W. (2015). Do actinic keratoses and superficial squamous cell carcinomas have a specific immunoprofile?. Actinic keratosis. (pp. 36-41) edited by H. Peter Soyer, Tarl W. Prow and Gregor B. E. Jemec. Basel, Switzerland: Karger AG. doi: 10.1159/000366533

Do actinic keratoses and superficial squamous cell carcinomas have a specific immunoprofile?

2015

Journal Article

CD4+/CD8+ double positive T cells: more than just a developmental stage?

Overgaard, Nana H., Jung, Ji-Won, Steptoe, Raymond J. and Wells, James W. (2015). CD4+/CD8+ double positive T cells: more than just a developmental stage?. Journal of Leukocyte Biology, 97 (1), 31-38. doi: 10.1189/jlb.1RU0814-382

CD4+/CD8+ double positive T cells: more than just a developmental stage?

2015

Journal Article

Genetics and nonmelanoma skin cancer in kidney transplant recipients

Burke, Michael T., Isbel, Nicole, Barraclough, Katherine A., Jung, Ji-Won, Wells, James W. and Staatz, Christine E. (2015). Genetics and nonmelanoma skin cancer in kidney transplant recipients. Pharmacogenomics, 16 (2), 161-172. doi: 10.2217/pgs.14.156

Genetics and nonmelanoma skin cancer in kidney transplant recipients

2014

Journal Article

HPV16-E7 expression in squamous epithelium creates a local immune suppressive environment via CCL2- and CCL5- mediated recruitment of mast cells

Bergot, Anne-Sophie, Ford, Neill, Leggatt, Graham R., Wells, James W., Frazer, Ian H. and Grimbaldeston, Michele A. (2014). HPV16-E7 expression in squamous epithelium creates a local immune suppressive environment via CCL2- and CCL5- mediated recruitment of mast cells. PLoS Pathogens, 10 (10) e1004466, 1-11. doi: 10.1371/journal.ppat.1004466

HPV16-E7 expression in squamous epithelium creates a local immune suppressive environment via CCL2- and CCL5- mediated recruitment of mast cells

2014

Journal Article

Comparative Immune Phenotypic Analysis of Cutaneous Squamous Cell Carcinoma and Intraepidermal Carcinoma in Immune-Competent Individuals: Proportional Representation of CD8+ T-Cells but Not FoxP3+ Regulatory T-Cells Is Associated with Disease Stage

Freeman, Andrew, Bridge, Jennifer A., Maruthayanar, Pirashanthini, Overgaard, Nana H., Jung, Ji-Won, Simpson, Fiona, Prow, Tarl W., Soyer, H. Peter, Frazer, Ian H., Freeman, Michael and Wells, James W. (2014). Comparative Immune Phenotypic Analysis of Cutaneous Squamous Cell Carcinoma and Intraepidermal Carcinoma in Immune-Competent Individuals: Proportional Representation of CD8+ T-Cells but Not FoxP3+ Regulatory T-Cells Is Associated with Disease Stage. PLoS One, 9 (10) e110928, e110928.1-e110928.9. doi: 10.1371/journal.pone.0110928

Comparative Immune Phenotypic Analysis of Cutaneous Squamous Cell Carcinoma and Intraepidermal Carcinoma in Immune-Competent Individuals: Proportional Representation of CD8+ T-Cells but Not FoxP3+ Regulatory T-Cells Is Associated with Disease Stage

2013

Journal Article

Inflammatory cytokines induce an unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrow

Ferreira, Elisabeth, Porter, Ryan M., Wehling, Nathalie, O'Sullivan, Regina P., Liu, Fangjun, Boskey, Adele, Estok, Daniel M., Harris, Mitchell B., Vrahas, Mark S., Evans, Christopher H. and Wells, James W. (2013). Inflammatory cytokines induce an unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrow. Journal of Biological Chemistry, 288 (41), 29494-29505. doi: 10.1074/jbc.M113.471268

Inflammatory cytokines induce an unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrow

2013

Journal Article

Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy

Coleman, Miranda A., Bridge, Jennifer A., Lane, Steven W., Dixon, Chantelle M., Hill, Geoffrey R., Wells, James W., Thomas, Ranjeny and Steptoe, Raymond J. (2013). Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy. Blood, 121 (6), 1049-1058. doi: 10.1182/blood-2012-06-434100

Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy