2016 Conference Publication Uncovering novel regulators of CD8(+) T-cell functions in the skinBridge, J. A., Overgaard, N. H., Cruz, J. L., Veitch, M., Frazer, I. H., Steptoe, R. J. and Wells, J. W. (2016). Uncovering novel regulators of CD8(+) T-cell functions in the skin. Asia-Pacific Combined Dermatology Research Conference, Noosa, Australia, 25–28 August 2016. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/ajd.12584 |
2016 Conference Publication Ablation of pathogenic memory T-cell responses by bone marrow-mediated gene therapy under immune-preserving conditionsSteptoe, R., Al-Kouba, J., Coleman, M., Jessup, C., Starkey, M., Overgaard, N., Bridge, J., Horvat, J., Werder, R., Walters, S., Coates, P. T., Grey, S., Thomas, R., Wells, J., Hansbro, P., Phipps, S. and Davies, J. (2016). Ablation of pathogenic memory T-cell responses by bone marrow-mediated gene therapy under immune-preserving conditions. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. |
2016 Conference Publication Preclinical modeling of EGFR-specific mAb and immune pathways that impact immunotherapics for squamous cell carcinomaHe, X., Cruz, Gonzalez J., Simpson, F. and Wells, J. (2016). Preclinical modeling of EGFR-specific mAb and immune pathways that impact immunotherapics for squamous cell carcinoma. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200 |
2016 Conference Publication The impact of rapamycin and tacrolimus treatment on resident CD8+T-cell populations in cutaneous squamous cell carcinomaJung, Ji-Won, Taylor, Paul J., Simpson, Fiona, Frazer, Ian H. and Wells, James W. (2016). The impact of rapamycin and tacrolimus treatment on resident CD8+T-cell populations in cutaneous squamous cell carcinoma. International Cancer Immunotherapy Conference: Translating Science into Survival, New York, United States, September 16-19, 2015. Philadelphia, United States: American Association for Cancer Research. doi: 10.1158/2326-6074.CRICIMTEATIAACR15-B055 |
2016 Conference Publication Does dendritic-cell targeted antigen expression induce both T and B cell tolerance?Brooks, J., Al-Kouba, J., Davies, J., Wells, J. and Steptoe, R. (2016). Does dendritic-cell targeted antigen expression induce both T and B cell tolerance?. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200 |
2015 Journal Article Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumorsMoyle, Peter M., Dai, Wei, Liu, Tzu-Yu, Hussein, Waleed M., Maruthayanar, Pirashanthini, Wells, James W., McMillan, Nigel A. J., Skwarczynski, Mariusz and Toth, Istvan (2015). Combined synthetic and recombinant techniques for the development of lipoprotein-based, self-adjuvanting vaccines targeting human papillomavirus type-16 associated tumors. Bioorganic and Medicinal Chemistry Letters, 25 (23), 5570-5575. doi: 10.1016/j.bmcl.2015.10.049 |
2015 Journal Article A High Through-put Platform for Recombinant Antibodies to Folded ProteinsHornsby, Michael, Paduch, Marcin, Miersch, Shane, Saeaef, Annika, Matsuguchi, Tet, Lee, Brian, Wypisniak, Karolina, Doak, Allison, King, Daniel, Usatyuk, Svitlana, Perry, Kimberly, Lu, Vince, Thomas, William, Luke, Judy, Goodman, Jay, Hoey, Robert J., Lai, Darson, Griffin, Carly, Li, Zhijian, Vizeacoumar, Franco J., Dong, Debbie, Campbell, Elliot, Anderson, Stephen, Zhong, Nan, Graeslund, Susanne, Koide, Shohei, Moffat, Jason, Sidhu, Sachdev, Kossiakoff, Anthony and Wells, James (2015). A High Through-put Platform for Recombinant Antibodies to Folded Proteins. Molecular & Cellular Proteomics, 14 (10), 2833-2847. doi: 10.1074/mcp.O115.052209 |
2015 Journal Article Rapid and reliable healing of critical size bone defects with genetically modified sheep muscleLiu, F., Ferreira, E., Porter, R. M., Glatt, V., Schinhan, M., Shen, Z., Randolph, M. A., Kirker-Head, C. A., Wehling, C., Vrahas, M. S., Evans, C. H. and Wells, J. W. (2015). Rapid and reliable healing of critical size bone defects with genetically modified sheep muscle. European Cells and Materials, 30 (30), 118-131. doi: 10.22203/eCM.v030a09 |
2015 Conference Publication Reprogramming caspase activity by directed evolution provides alternate solutions for substrate recognitionMacPherson, Derek, Hill, Maureen, Wu, Peng, Julien, Olivier, Wells, James and Hardy, Jeanne (2015). Reprogramming caspase activity by directed evolution provides alternate solutions for substrate recognition. WASHINGTON: AMER CHEMICAL SOC. |
2015 Journal Article Impaired T-cell function in B-cell lymphoma: a direct consequence of events at the immunological synapse?Roufaiel, Marian Nassef Kadry Naguib, Wells, James W. and Steptoe, Raymond J. (2015). Impaired T-cell function in B-cell lymphoma: a direct consequence of events at the immunological synapse?. Frontiers in Immunology, 6 (JUN) 258, 258.1-258.10. doi: 10.3389/fimmu.2015.00258 |
2015 Journal Article A novel zinc finger gene, ZNF465, is inappropriately expressed in acute myeloid leukaemia cellsCollin, Joseph F., Wells, James W., Czepulkowski, Barbara, Lyne, Linden, Duriez, Patrick J., Banham, Alison H., Mufti, Ghulam J. and Guinn, Barbara-ann (2015). A novel zinc finger gene, ZNF465, is inappropriately expressed in acute myeloid leukaemia cells. Genes Chromosomes Cancer, 54 (5), 288-302. doi: 10.1002/gcc.22242 |
2015 Journal Article Does the nature of residual immune function explain the differential risk of non-melanoma skin cancer development in immunosuppressed organ transplant recipients?Jung, Ji-Won, Overgaard, Nana H., Burke, Michael T., Isbel, Nicole, Frazer, Ian H., Simpson, Fiona and Wells, James W. (2015). Does the nature of residual immune function explain the differential risk of non-melanoma skin cancer development in immunosuppressed organ transplant recipients?. International Journal of Cancer, 138 (2), 281-292. doi: 10.1002/ijc.29450 |
2015 Journal Article HPV16 E7 expression in skin induces TSLP secretion, type 2 ILC infiltration and atopic dermatitis-like lesionsBergot, Anne-Sophie, Monnet, Nastasia, Tran, Son Le, Mittal, Deepak, Al-Kouba, Jane, Steptoe, Raymond J., Grimbaldeston, Michele A., Frazer, Ian H. and Wells, James W. (2015). HPV16 E7 expression in skin induces TSLP secretion, type 2 ILC infiltration and atopic dermatitis-like lesions. Immunology and Cell Biology, 93 (6), 540-547. doi: 10.1038/icb.2014.123 |
2015 Book Chapter Do actinic keratoses and superficial squamous cell carcinomas have a specific immunoprofile?Wells, James W. (2015). Do actinic keratoses and superficial squamous cell carcinomas have a specific immunoprofile?. Actinic keratosis. (pp. 36-41) edited by H. Peter Soyer, Tarl W. Prow and Gregor B. E. Jemec. Basel, Switzerland: Karger AG. doi: 10.1159/000366533 |
2015 Journal Article CD4+/CD8+ double positive T cells: more than just a developmental stage?Overgaard, Nana H., Jung, Ji-Won, Steptoe, Raymond J. and Wells, James W. (2015). CD4+/CD8+ double positive T cells: more than just a developmental stage?. Journal of Leukocyte Biology, 97 (1), 31-38. doi: 10.1189/jlb.1RU0814-382 |
2015 Journal Article Genetics and nonmelanoma skin cancer in kidney transplant recipientsBurke, Michael T., Isbel, Nicole, Barraclough, Katherine A., Jung, Ji-Won, Wells, James W. and Staatz, Christine E. (2015). Genetics and nonmelanoma skin cancer in kidney transplant recipients. Pharmacogenomics, 16 (2), 161-172. doi: 10.2217/pgs.14.156 |
2014 Journal Article HPV16-E7 expression in squamous epithelium creates a local immune suppressive environment via CCL2- and CCL5- mediated recruitment of mast cellsBergot, Anne-Sophie, Ford, Neill, Leggatt, Graham R., Wells, James W., Frazer, Ian H. and Grimbaldeston, Michele A. (2014). HPV16-E7 expression in squamous epithelium creates a local immune suppressive environment via CCL2- and CCL5- mediated recruitment of mast cells. PLoS Pathogens, 10 (10) e1004466, 1-11. doi: 10.1371/journal.ppat.1004466 |
2014 Journal Article Comparative Immune Phenotypic Analysis of Cutaneous Squamous Cell Carcinoma and Intraepidermal Carcinoma in Immune-Competent Individuals: Proportional Representation of CD8+ T-Cells but Not FoxP3+ Regulatory T-Cells Is Associated with Disease StageFreeman, Andrew, Bridge, Jennifer A., Maruthayanar, Pirashanthini, Overgaard, Nana H., Jung, Ji-Won, Simpson, Fiona, Prow, Tarl W., Soyer, H. Peter, Frazer, Ian H., Freeman, Michael and Wells, James W. (2014). Comparative Immune Phenotypic Analysis of Cutaneous Squamous Cell Carcinoma and Intraepidermal Carcinoma in Immune-Competent Individuals: Proportional Representation of CD8+ T-Cells but Not FoxP3+ Regulatory T-Cells Is Associated with Disease Stage. PLoS One, 9 (10) e110928, e110928.1-e110928.9. doi: 10.1371/journal.pone.0110928 |
2013 Journal Article Inflammatory cytokines induce an unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrowFerreira, Elisabeth, Porter, Ryan M., Wehling, Nathalie, O'Sullivan, Regina P., Liu, Fangjun, Boskey, Adele, Estok, Daniel M., Harris, Mitchell B., Vrahas, Mark S., Evans, Christopher H. and Wells, James W. (2013). Inflammatory cytokines induce an unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrow. Journal of Biological Chemistry, 288 (41), 29494-29505. doi: 10.1074/jbc.M113.471268 |
2013 Journal Article Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacyColeman, Miranda A., Bridge, Jennifer A., Lane, Steven W., Dixon, Chantelle M., Hill, Geoffrey R., Wells, James W., Thomas, Ranjeny and Steptoe, Raymond J. (2013). Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy. Blood, 121 (6), 1049-1058. doi: 10.1182/blood-2012-06-434100 |