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2014 Journal Article Comparative Immune Phenotypic Analysis of Cutaneous Squamous Cell Carcinoma and Intraepidermal Carcinoma in Immune-Competent Individuals: Proportional Representation of CD8+ T-Cells but Not FoxP3+ Regulatory T-Cells Is Associated with Disease StageFreeman, Andrew, Bridge, Jennifer A., Maruthayanar, Pirashanthini, Overgaard, Nana H., Jung, Ji-Won, Simpson, Fiona, Prow, Tarl W., Soyer, H. Peter, Frazer, Ian H., Freeman, Michael and Wells, James W. (2014). Comparative Immune Phenotypic Analysis of Cutaneous Squamous Cell Carcinoma and Intraepidermal Carcinoma in Immune-Competent Individuals: Proportional Representation of CD8+ T-Cells but Not FoxP3+ Regulatory T-Cells Is Associated with Disease Stage. PLoS One, 9 (10) e110928, e110928.1-e110928.9. doi: 10.1371/journal.pone.0110928 |
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2013 Journal Article Inflammatory cytokines induce an unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrowFerreira, Elisabeth, Porter, Ryan M., Wehling, Nathalie, O'Sullivan, Regina P., Liu, Fangjun, Boskey, Adele, Estok, Daniel M., Harris, Mitchell B., Vrahas, Mark S., Evans, Christopher H. and Wells, James W. (2013). Inflammatory cytokines induce an unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrow. Journal of Biological Chemistry, 288 (41), 29494-29505. doi: 10.1074/jbc.M113.471268 |
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2013 Journal Article Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacyColeman, Miranda A., Bridge, Jennifer A., Lane, Steven W., Dixon, Chantelle M., Hill, Geoffrey R., Wells, James W., Thomas, Ranjeny and Steptoe, Raymond J. (2013). Tolerance induction with gene-modified stem cells and immune-preserving conditioning in primed mice: restricting antigen to differentiated antigen-presenting cells permits efficacy. Blood, 121 (6), 1049-1058. doi: 10.1182/blood-2012-06-434100 |
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2013 Journal Article Arginase treatment prevents the recovery of canine lymphoma and osteosarcoma cells resistant to the toxic effects of prolonged arginine deprivationWells, James W., Evans, Christopher H., Scott, Milcah C., Ruetgen, Barbara C., O'Brien, Timothy D., Modiano, Jaime F., Cvetkovic, Goran and Tepic, Slobodan (2013). Arginase treatment prevents the recovery of canine lymphoma and osteosarcoma cells resistant to the toxic effects of prolonged arginine deprivation. PLoS One, 8 (1) e54464, e54464.1-e54464.9. doi: 10.1371/journal.pone.0054464 |
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2012 Journal Article EWS-FLI-1-targeted cytotoxic T-cell killing of multiple tumor types belonging to the Ewing Sarcoma Family of TumorsEvans, Christopher H., Liu, Fangjun, Porter, Ryan M., O'Sullivan, Regina P., Merghoub, Taha, Lunsford, Elaine P., Robichaud, Kyle, Van Valen, Frans, Lessnick, Stephen L., Gebhardt, Mark C. and Wells, James W. (2012). EWS-FLI-1-targeted cytotoxic T-cell killing of multiple tumor types belonging to the Ewing Sarcoma Family of Tumors. Clinical Cancer Research, 18 (19), 5341-5351. doi: 10.1158/1078-0432.CCR-12-1985 |
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2011 Journal Article Evaluation of BMP-2 gene-activated muscle grafts for cranial defect repair.Liu, Fangjun, Porter, Ryan M., Wells, James, Glatt, Vaida, Pilapil, Carmencita and Evans, Christopher H. (2011). Evaluation of BMP-2 gene-activated muscle grafts for cranial defect repair.. Journal of Orthopaedic Research, 30 (7), 1095-1102. doi: 10.1002/jor.22038 |
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2010 Conference Publication Inflammation and Osteogensis: a Paradoxical Effect of Interleukin-1 On the Osteogenic Differentiation of Human, Bone Marrow-Derived Mesenchymal Stem CellsFerreira, Elisabeth, Wells, James W. and Evans, Christopher H. (2010). Inflammation and Osteogensis: a Paradoxical Effect of Interleukin-1 On the Osteogenic Differentiation of Human, Bone Marrow-Derived Mesenchymal Stem Cells. 16th International Conference of the Inflammation-Research-Association, Chantilly Va, 2008. BIRKHAUSER VERLAG AG. |
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2010 Conference Publication Immune Gene Therapy for Acute Myeloid LeukaemiaFarzaneh, Farzin, Chan, Lucas, Hardwick, Nicola, Ingram, Wendy, Mufti, Ghulam, Aloysius, Mark, Robins, Adrian, Habib, Nagy, Bhalla, Joti, Eremin, Oleg, Jun, Tye Gee, Oppenheim, David, Wells, James, Cowled, Christopher and Noble, Alistair (2010). Immune Gene Therapy for Acute Myeloid Leukaemia. 17th Annual Meeting of German-Society-for-Gene-Therapy (DG-GT e.V.), Munich, Germany, 7 - 9 October 2010. New Rochelle, NY United States: Mary Ann Liebert, Inc. Publishers. |
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2009 Journal Article Use of genetically modified muscle and fat grafts to repair defects in bone and cartilageEvans, C.H., Liu, F.-J., Glatt, V., Hoyland, J. A., Kirker-Head, C., Walsh, A., Betz, O., Wells, J. W., Betz, V., Porter, R. M., Saad, F. A., Gerstenfeld, L. C., Einhorn, T. A., Harris, M. B. and Vrahas, M. S. (2009). Use of genetically modified muscle and fat grafts to repair defects in bone and cartilage. European Cells and Materials, 18, 96-111. |
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2009 Journal Article Suppression of airway inflammation by a natural acute infection of the intestinal epitheliumGibbons, D. L., Haque, S. F. Y., Copestake, S. L., Wells, J. W. and Hayday, A. C. (2009). Suppression of airway inflammation by a natural acute infection of the intestinal epithelium. Mucosal Immunology, 2 (2), 144-155. doi: 10.1038/mi.2008.83 |
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2009 Journal Article Interleukin-1 beta and Tumor Necrosis Factor alpha Inhibit Chondrogenesis by Human Mesenchymal Stem Cells Through NF-kappa B-Dependent PathwaysWehling, N., Palmer, G. D., Pilapil, C., Liu, F., Wells, J. W., Muller, P. E., Evans, C. H. and Porter, R. M. (2009). Interleukin-1 beta and Tumor Necrosis Factor alpha Inhibit Chondrogenesis by Human Mesenchymal Stem Cells Through NF-kappa B-Dependent Pathways. Arthritis and Rheumatism, 60 (3), 801-812. doi: 10.1002/art.24352 |
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2009 Journal Article Anti-tumor immunity in a model of acute myeloid leukemiaCheuk, Adam T. C., Wells, James W., Chan, Lucas, Westwood, Nigel B., Berger, Stuart A., Yagita, Hideo, Okumura, Ko, Farzaneh, Farzin, Mufti, Ghulam J. and Guinn, Barbara-Ann (2009). Anti-tumor immunity in a model of acute myeloid leukemia. Leukemia and Lymphoma, 50 (3), 447-454. doi: 10.1080/10428190802653776 |
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2009 Journal Article Suppression of allergic airway inflammation and IgE responses by a class I restricted allergen peptide vaccineWells, J. W., Choy, K., Lloyd, C. M. and Noble, A. (2009). Suppression of allergic airway inflammation and IgE responses by a class I restricted allergen peptide vaccine. Mucosal Immunology, 2 (1), 54-62. doi: 10.1038/mi.2008.69 |
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2008 Journal Article Innate responsiveness of CD8 memory T-cell populations nonspecifically inhibits allergic sensitizationLeggat, Jamie A., Gibbons, Deena L., Haque, Syeda F. Y., Smith, Adrian L., Wells, James W., Choy, Katherine, Lloyd, Clare M., Hayday, Adrian C. and Noble, Alistair (2008). Innate responsiveness of CD8 memory T-cell populations nonspecifically inhibits allergic sensitization. Journal of Allergy and Clinical Immunology, 122 (5), 1014-1021. doi: 10.1016/j.jaci.2008.08.011 |
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2008 Journal Article Combined triggering of dendritic cell receptors results in synergistic activation and potent cytotoxic immunityWells, J. W., Cowled, C. J., Farzaneh, F. and Noble, A. (2008). Combined triggering of dendritic cell receptors results in synergistic activation and potent cytotoxic immunity. Journal of Immunology, 181 (5), 3422-3431. doi: 10.4049/jimmunol.181.5.3422 |
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2008 Other Outputs Composition comprising a cytotoxic t-cell - inducing adjuvantWells, James William and Noble, Alistair (2008). Composition comprising a cytotoxic t-cell - inducing adjuvant. WO2007122392-A8. |
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2008 Conference Publication Characterization and utilization of mesenchymal progenitor cells recovered with the Reamer-irrigator-aspiratorPorter, R. M., Ivkovic, A., Wells, J., Glatt, V., Harris, M. B., Vrahas, M. S. and Evans, C. (2008). Characterization and utilization of mesenchymal progenitor cells recovered with the Reamer-irrigator-aspirator. ECM IX: Musculoskeletal Trauma - 50 Years of AO Research, Davos, Switzerland, 15-18 June, 2008. Clavadelstr, Davos, Switzerland: Swiss Society for Biomaterials. |
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2008 Conference Publication Expedited strategies for the restoration of boneEvans, C. H., Glatt, V., Liu, F.-J., Wells, J. W., Ferreira, E., Vrahas, M. S., Harris, M. B., Ivkovic, A. and Porter, R. M. (2008). Expedited strategies for the restoration of bone. The Second International Symposium on Biotechnology in Musculoskeletal Repair, Lausanne, Switzerland, 2-4 October, 2008. Clavadelstr, Davos, Switzerland: Swiss Society for Biomaterials. |
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2008 Conference Publication Improving the osteogenic behaviour of human mesenchymal stromal cellsIvkovic, A., Porter, R. M., Wells, J. W. and Evans, C. H. (2008). Improving the osteogenic behaviour of human mesenchymal stromal cells. ECM IX: Musculoskeletal Trauma - 50 Years of AO Research, Davos, Switzerland, 15-18 June, 2008. Clavadelstr, Davos, Switzerland: Swiss Society for Biomaterials. |
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2008 Conference Publication Pro-inflammatory cytokines inhibit chondrogenesis by human mesenchymal stem cells through NF-(kappa)B-dependent pathwaysPorter, R. M., Wehling, N., Palmer, G. D., Wells, J. W., Muller, P. E. and Evans, C. H. (2008). Pro-inflammatory cytokines inhibit chondrogenesis by human mesenchymal stem cells through NF-(kappa)B-dependent pathways. ECM IX: Musculoskeletal Trauma - 50 Years of AO Research, Davos, Switzerland, 15-18 June, 2008. Clavadelstr, Davos, Switzerland: Swiss Society for Biomaterials. |
