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2011

Journal Article

Evaluation of BMP-2 gene-activated muscle grafts for cranial defect repair.

Liu, Fangjun, Porter, Ryan M., Wells, James, Glatt, Vaida, Pilapil, Carmencita and Evans, Christopher H. (2011). Evaluation of BMP-2 gene-activated muscle grafts for cranial defect repair.. Journal of Orthopaedic Research, 30 (7), 1095-1102. doi: 10.1002/jor.22038

Evaluation of BMP-2 gene-activated muscle grafts for cranial defect repair.

2010

Conference Publication

Inflammation and Osteogensis: a Paradoxical Effect of Interleukin-1 On the Osteogenic Differentiation of Human, Bone Marrow-Derived Mesenchymal Stem Cells

Ferreira, Elisabeth, Wells, James W. and Evans, Christopher H. (2010). Inflammation and Osteogensis: a Paradoxical Effect of Interleukin-1 On the Osteogenic Differentiation of Human, Bone Marrow-Derived Mesenchymal Stem Cells. 16th International Conference of the Inflammation-Research-Association, Chantilly Va, 2008. BIRKHAUSER VERLAG AG.

Inflammation and Osteogensis: a Paradoxical Effect of Interleukin-1 On the Osteogenic Differentiation of Human, Bone Marrow-Derived Mesenchymal Stem Cells

2010

Conference Publication

Immune Gene Therapy for Acute Myeloid Leukaemia

Farzaneh, Farzin, Chan, Lucas, Hardwick, Nicola, Ingram, Wendy, Mufti, Ghulam, Aloysius, Mark, Robins, Adrian, Habib, Nagy, Bhalla, Joti, Eremin, Oleg, Jun, Tye Gee, Oppenheim, David, Wells, James, Cowled, Christopher and Noble, Alistair (2010). Immune Gene Therapy for Acute Myeloid Leukaemia. 17th Annual Meeting of German-Society-for-Gene-Therapy (DG-GT e.V.), Munich, Germany, 7 - 9 October 2010. New Rochelle, NY United States: Mary Ann Liebert, Inc. Publishers.

Immune Gene Therapy for Acute Myeloid Leukaemia

2009

Journal Article

Use of genetically modified muscle and fat grafts to repair defects in bone and cartilage

Evans, C.H., Liu, F.-J., Glatt, V., Hoyland, J. A., Kirker-Head, C., Walsh, A., Betz, O., Wells, J. W., Betz, V., Porter, R. M., Saad, F. A., Gerstenfeld, L. C., Einhorn, T. A., Harris, M. B. and Vrahas, M. S. (2009). Use of genetically modified muscle and fat grafts to repair defects in bone and cartilage. European Cells and Materials, 18, 96-111.

Use of genetically modified muscle and fat grafts to repair defects in bone and cartilage

2009

Journal Article

Suppression of airway inflammation by a natural acute infection of the intestinal epithelium

Gibbons, D. L., Haque, S. F. Y., Copestake, S. L., Wells, J. W. and Hayday, A. C. (2009). Suppression of airway inflammation by a natural acute infection of the intestinal epithelium. Mucosal Immunology, 2 (2), 144-155. doi: 10.1038/mi.2008.83

Suppression of airway inflammation by a natural acute infection of the intestinal epithelium

2009

Journal Article

Interleukin-1 beta and Tumor Necrosis Factor alpha Inhibit Chondrogenesis by Human Mesenchymal Stem Cells Through NF-kappa B-Dependent Pathways

Wehling, N., Palmer, G. D., Pilapil, C., Liu, F., Wells, J. W., Muller, P. E., Evans, C. H. and Porter, R. M. (2009). Interleukin-1 beta and Tumor Necrosis Factor alpha Inhibit Chondrogenesis by Human Mesenchymal Stem Cells Through NF-kappa B-Dependent Pathways. Arthritis and Rheumatism, 60 (3), 801-812. doi: 10.1002/art.24352

Interleukin-1 beta and Tumor Necrosis Factor alpha Inhibit Chondrogenesis by Human Mesenchymal Stem Cells Through NF-kappa B-Dependent Pathways

2009

Journal Article

Anti-tumor immunity in a model of acute myeloid leukemia

Cheuk, Adam T. C., Wells, James W., Chan, Lucas, Westwood, Nigel B., Berger, Stuart A., Yagita, Hideo, Okumura, Ko, Farzaneh, Farzin, Mufti, Ghulam J. and Guinn, Barbara-Ann (2009). Anti-tumor immunity in a model of acute myeloid leukemia. Leukemia and Lymphoma, 50 (3), 447-454. doi: 10.1080/10428190802653776

Anti-tumor immunity in a model of acute myeloid leukemia

2009

Journal Article

Suppression of allergic airway inflammation and IgE responses by a class I restricted allergen peptide vaccine

Wells, J. W., Choy, K., Lloyd, C. M. and Noble, A. (2009). Suppression of allergic airway inflammation and IgE responses by a class I restricted allergen peptide vaccine. Mucosal Immunology, 2 (1), 54-62. doi: 10.1038/mi.2008.69

Suppression of allergic airway inflammation and IgE responses by a class I restricted allergen peptide vaccine

2008

Journal Article

Innate responsiveness of CD8 memory T-cell populations nonspecifically inhibits allergic sensitization

Leggat, Jamie A., Gibbons, Deena L., Haque, Syeda F. Y., Smith, Adrian L., Wells, James W., Choy, Katherine, Lloyd, Clare M., Hayday, Adrian C. and Noble, Alistair (2008). Innate responsiveness of CD8 memory T-cell populations nonspecifically inhibits allergic sensitization. Journal of Allergy and Clinical Immunology, 122 (5), 1014-1021. doi: 10.1016/j.jaci.2008.08.011

Innate responsiveness of CD8 memory T-cell populations nonspecifically inhibits allergic sensitization

2008

Journal Article

Combined triggering of dendritic cell receptors results in synergistic activation and potent cytotoxic immunity

Wells, J. W., Cowled, C. J., Farzaneh, F. and Noble, A. (2008). Combined triggering of dendritic cell receptors results in synergistic activation and potent cytotoxic immunity. Journal of Immunology, 181 (5), 3422-3431. doi: 10.4049/jimmunol.181.5.3422

Combined triggering of dendritic cell receptors results in synergistic activation and potent cytotoxic immunity

2008

Other Outputs

Composition comprising a cytotoxic t-cell - inducing adjuvant

Wells, James William and Noble, Alistair (2008). Composition comprising a cytotoxic t-cell - inducing adjuvant. WO2007122392-A8.

Composition comprising a cytotoxic t-cell - inducing adjuvant

2008

Conference Publication

Characterization and utilization of mesenchymal progenitor cells recovered with the Reamer-irrigator-aspirator

Porter, R. M., Ivkovic, A., Wells, J., Glatt, V., Harris, M. B., Vrahas, M. S. and Evans, C. (2008). Characterization and utilization of mesenchymal progenitor cells recovered with the Reamer-irrigator-aspirator. ECM IX: Musculoskeletal Trauma - 50 Years of AO Research, Davos, Switzerland, 15-18 June, 2008. Clavadelstr, Davos, Switzerland: Swiss Society for Biomaterials.

Characterization and utilization of mesenchymal progenitor cells recovered with the Reamer-irrigator-aspirator

2008

Conference Publication

Expedited strategies for the restoration of bone

Evans, C. H., Glatt, V., Liu, F.-J., Wells, J. W., Ferreira, E., Vrahas, M. S., Harris, M. B., Ivkovic, A. and Porter, R. M. (2008). Expedited strategies for the restoration of bone. The Second International Symposium on Biotechnology in Musculoskeletal Repair, Lausanne, Switzerland, 2-4 October, 2008. Clavadelstr, Davos, Switzerland: Swiss Society for Biomaterials.

Expedited strategies for the restoration of bone

2008

Conference Publication

Improving the osteogenic behaviour of human mesenchymal stromal cells

Ivkovic, A., Porter, R. M., Wells, J. W. and Evans, C. H. (2008). Improving the osteogenic behaviour of human mesenchymal stromal cells. ECM IX: Musculoskeletal Trauma - 50 Years of AO Research, Davos, Switzerland, 15-18 June, 2008. Clavadelstr, Davos, Switzerland: Swiss Society for Biomaterials.

Improving the osteogenic behaviour of human mesenchymal stromal cells

2008

Conference Publication

Pro-inflammatory cytokines inhibit chondrogenesis by human mesenchymal stem cells through NF-(kappa)B-dependent pathways

Porter, R. M., Wehling, N., Palmer, G. D., Wells, J. W., Muller, P. E. and Evans, C. H. (2008). Pro-inflammatory cytokines inhibit chondrogenesis by human mesenchymal stem cells through NF-(kappa)B-dependent pathways. ECM IX: Musculoskeletal Trauma - 50 Years of AO Research, Davos, Switzerland, 15-18 June, 2008. Clavadelstr, Davos, Switzerland: Swiss Society for Biomaterials.

Pro-inflammatory cytokines inhibit chondrogenesis by human mesenchymal stem cells through NF-(kappa)B-dependent pathways

2007

Journal Article

Semi-allogeneic dendritic cells can induce antigen-specific T-cell activation, which is not enhanced by concurrent alloreactivity

Wells, James W., Cowled, Chris J., Darling, David, Guinn, Barbara-Ann, Farzaneh, Farzin, Noble, Alistair and Galea-Lauri, Joanna (2007). Semi-allogeneic dendritic cells can induce antigen-specific T-cell activation, which is not enhanced by concurrent alloreactivity. Cancer Immunology Immunotherapy, 56 (12), 1861-1873. doi: 10.1007/s00262-007-0328-x

Semi-allogeneic dendritic cells can induce antigen-specific T-cell activation, which is not enhanced by concurrent alloreactivity

2007

Journal Article

Regulation of allergic airway inflammation by class I-restricted allergen presentation and CD8 T-cell infiltration

Wells, James W., Cowled, Christopher J., Giorgini, Angela, Kemeny, David M. and Noble, Alistair (2007). Regulation of allergic airway inflammation by class I-restricted allergen presentation and CD8 T-cell infiltration. Journal of Allergy and Clinical Immunology, 119 (1), 226-234. doi: 10.1016/j.jaci.2006.09.004

Regulation of allergic airway inflammation by class I-restricted allergen presentation and CD8 T-cell infiltration

2005

Conference Publication

Local cross-presentation of allergen to CD8 cells by lung dendritic cells regulates allergic airways inflammation

Wells, JW, Cowled, CJ, Giorgini, A, Noble, A and Kemeny, DM (2005). Local cross-presentation of allergen to CD8 cells by lung dendritic cells regulates allergic airways inflammation. BLACKWELL PUBLISHING.

Local cross-presentation of allergen to CD8 cells by lung dendritic cells regulates allergic airways inflammation

2005

Journal Article

Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia

Guinn, Barbara-ann, Bland, Elizabeth A., Lodi, Usman, Liggins, Amanda P., Tobal, Khalid, Petters, Sarah, Wells, James W., Banham, Alison H. and Mufti, Ghulam J. (2005). Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia. Biochemical and Biophysical Research Communications, 335 (4), 1293-1304. doi: 10.1016/j.bbrc.2005.08.024

Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia

2005

Conference Publication

HCV core protein interferes with mhc class irestricted antigen processing/presentation by murine dendritic cells

O'Beirne, JP, Cross, T, Wells, J, Farzaneh, F and Harrison, PM (2005). HCV core protein interferes with mhc class irestricted antigen processing/presentation by murine dendritic cells. 40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver, Paris France, Apr 13-17, 2005. ELSEVIER SCIENCE BV.

HCV core protein interferes with mhc class irestricted antigen processing/presentation by murine dendritic cells