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2021 Journal Article PD-1 and beyond to activate T cells in cutaneous squamous cell cancers: the case for 4-1BB and VISTA antibodies in combination therapyWright, Quentin, Gonzalez Cruz, Jazmina L., Wells, James W. and Leggatt, Graham R. (2021). PD-1 and beyond to activate T cells in cutaneous squamous cell cancers: the case for 4-1BB and VISTA antibodies in combination therapy. Cancers, 13 (13) 3310, 3310. doi: 10.3390/cancers13133310 |
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2021 Journal Article Evolution of cancer vaccines—challenges, achievements and future directionsTay, Ban Qi, Wright, Quentin, Ladwa, Rahul, Perry, Christopher, Leggatt, Graham, Simpson, Fiona, Wells, James W., Panizza, Benedict J., Frazer, Ian H. and Cruz, Jazmina L. G. (2021). Evolution of cancer vaccines—challenges, achievements and future directions. Vaccines, 9 (5) 535, 535. doi: 10.3390/vaccines9050535 |
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2021 Journal Article IFN-γ critically enables the intratumoural infiltration of CXCR3+ CD8+ T cells to drive squamous cell carcinoma regressionZeng, Zhen, Veitch, Margaret, Kelly, Gabrielle A., Tuong, Zewen K., Cruz, Jazmina G., Frazer, Ian H. and Wells, James W. (2021). IFN-γ critically enables the intratumoural infiltration of CXCR3+ CD8+ T cells to drive squamous cell carcinoma regression. Cancers, 13 (9) 2131, 2131. doi: 10.3390/cancers13092131 |
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2021 Journal Article Healing of sub-critical femoral osteotomies in mice is unaffected by tacrolimus and deletion of recombination activating gene 1Liu, T-Y, Bartnikowski, M., Wu, A. C., Veitch, M., Sokolowski, K. A., Millard, S. M., Pettit, A. R., Glatt, V., Evans, C. H. and Wells, J. W. (2021). Healing of sub-critical femoral osteotomies in mice is unaffected by tacrolimus and deletion of recombination activating gene 1. European Cells and Materials, 41, 345-354. doi: 10.22203/eCM.v041a22 |
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2021 Journal Article Investigating T cell immunity in cancer: achievements and prospectsZeng, Zhen, Chew, Hui Yi, Cruz, Jazmina G., Leggatt, Graham R. and Wells, James W. (2021). Investigating T cell immunity in cancer: achievements and prospects. International Journal of Molecular Sciences, 22 (6) 2907, 1-17. doi: 10.3390/ijms22062907 |
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2021 Journal Article Manganese-doped silica-based nanoparticles promote the efficacy of antigen-specific immunotherapyChandra, Janin, Teoh, Siok Min, Kuo, Paula, Tolley, Lynn, Bashaw, Abate Assefa, Tuong, Zewen Kelvin, Liu, Yang, Chen, Zibin, Wells, James W., Yu, Chengzhong, Frazer, Ian H. and Yu, Meihua (2021). Manganese-doped silica-based nanoparticles promote the efficacy of antigen-specific immunotherapy. The Journal of Immunology, 206 (5), ji2000355-998. doi: 10.4049/jimmunol.2000355 |
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2020 Journal Article Peripheral tolerance checkpoints imposed by ubiquitous antigen expression limit antigen-specific B cell responses under strongly immunogenic conditionsBrooks, Jeremy F., Murphy, Peter R., Barber, James E. M., Wells, James W. and Steptoe, Raymond J. (2020). Peripheral tolerance checkpoints imposed by ubiquitous antigen expression limit antigen-specific B cell responses under strongly immunogenic conditions. The Journal of Immunology, 205 (5), ji2000377-1247. doi: 10.4049/jimmunol.2000377 |
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2020 Journal Article Safety, tolerability and immunogenicity of influenza vaccination with a high-density microarray patch: results from a randomized, controlled phase I clinical trialForster, Angus H, Witham, Katey, Depelsenaire, Alexandra C.I., Veitch, Margaret, Wells, James W., Wheatley, Adam, Pryor, Melinda, Lickliter, Jason, Francis, Barbara, Rockman, Steve, Bodle, Jesse, Treasure, Peter, Hickling, Julian and Fernando, Germain J.P. (2020). Safety, tolerability and immunogenicity of influenza vaccination with a high-density microarray patch: results from a randomized, controlled phase I clinical trial. PLoS Medicine, 17 (3) e1003024, e1003024. doi: 10.1371/journal.pmed.1003024 |
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2020 Journal Article Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating AntibodiesChew, Hui Yi, De Lima, Priscila O., Gonzalez Cruz, Jazmina L., Banushi, Blerida, Echejoh, Godwins, Hu, Lingbo, Joseph, Shannon R., Lum, Benedict, Rae, James, O'Donnell, Jake S., Merida de Long, Lilia, Okano, Satomi, King, Brigid, Barry, Rachael, Moi, Davide, Mazzieri, Roberta, Thomas, Ranjeny, Souza-Fonseca-Guimaraes, Fernando, Foote, Matthew, McCluskey, Adam, Robinson, Phillip J., Frazer, Ian H., Saunders, Nicholas A., Parton, Robert G., Dolcetti, Riccardo, Cuff, Katharine, Martin, Jennifer H., Panizza, Benedict, Walpole, Euan ... Simpson, Fiona (2020). Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies. Cell, 180 (5), 895-914.e27. doi: 10.1016/j.cell.2020.02.019 |
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2020 Journal Article Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccinesSkwarczynski, Mariusz, Zhao, Guangzu, Boer, Jennifer C., Ozberk, Victoria, Azuar, Armira, Gonzalez Cruz, Jazmina, Kumar Giddam, Ashwini, Khalil, Zeinab G., Pandey, Manisha, Shibu, Mohini A., Hussein, Waleed M., Nevagi, Reshma J., Batzloff, Michael R., Wells, James W., Capon, Robert J., Plebanski, Magdalena, Good, Michael F. and Toth, Istvan (2020). Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines. Science Advances, 6 (5) eaax2285, eaax2285. doi: 10.1126/sciadv.aax2285 |
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2020 Journal Article Transfer of antigen-encoding bone marrow under immune-preserving conditions deletes mature antigen-specific B cells in recipients and inhibits antigen-specific antibody productionBrooks, Jeremy F., Barber, James E.M., Davies, Janet M., Wells, James W. and Steptoe, Raymond J. (2020). Transfer of antigen-encoding bone marrow under immune-preserving conditions deletes mature antigen-specific B cells in recipients and inhibits antigen-specific antibody production. Cytotherapy, 22 (8), 436-444. doi: 10.1016/j.jcyt.2020.04.041 |
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2019 Journal Article Cytokine/chemokine profiles in squamous cell carcinoma correlate with precancerous and cancerous disease stageTuong, Zewen, Lewandowski, Andrew, Bridge, Jennifer, Gonzalez-Cruz, Jazmina, Yamada, Miko, Lambie, Duncan, Lewandowski, Richard, Steptoe, Raymond, Leggatt, Graham, Simpson, Fiona, Frazer, Ian, Soyer, Peter and Wells, James W. (2019). Cytokine/chemokine profiles in squamous cell carcinoma correlate with precancerous and cancerous disease stage. Scientific Reports, 9 (1) 17754, 17754. doi: 10.1038/s41598-019-54435-0 |
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2019 Journal Article Editorial: Insights into biomarkers, cytokines, and chemokines in skin cancerBarrett, Lucy W., Gray, Elin S., Wells, James W. and Waithman, Jason (2019). Editorial: Insights into biomarkers, cytokines, and chemokines in skin cancer. Frontiers in Medicine, 6 199, 199. doi: 10.3389/fmed.2019.00199 |
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2019 Journal Article Bacillus anthracis Protective Antigen Shows High Specificity for a UV Induced Mouse Model of Cutaneous Squamous Cell CarcinomaCrawford, Theo, Fletcher, Nicholas, Veitch, Margaret, Gonzalez Cruz, Jazmina L., Pett, Nicola, Brereton, Ian, Wells, James W., Mobli, Mehdi and Tesiram, Yasvir (2019). Bacillus anthracis Protective Antigen Shows High Specificity for a UV Induced Mouse Model of Cutaneous Squamous Cell Carcinoma. Frontiers in Medicine, 6 (FEB) 22, 22. doi: 10.3389/fmed.2019.00022 |
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2019 Conference Publication The involvement of IFN-gamma and CXCR3 in the CD8(+) T-cell-mediated regression of squamous cell carcinomaZeng, Z., Cruz, J. G., Pett, N., Veitch, M., Frazer, I. H. and Wells, J. W. (2019). The involvement of IFN-gamma and CXCR3 in the CD8(+) T-cell-mediated regression of squamous cell carcinoma. 17th International Congress of Immunology (IUIS), Beijing, Peoples R China, 19-23 October 2019. Weinheim, Germany: Wiley. |
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2019 Conference Publication Antigen-encoding bone marrow deletes mature antigen-specific B cells in recipients and inhibits antigen-specific antibody productionSteptoe, R. J., Brooks, J. F. and Wells, J. W. (2019). Antigen-encoding bone marrow deletes mature antigen-specific B cells in recipients and inhibits antigen-specific antibody production. ESGCT 27th Annual Congress in collaboration with SETGyc Meeting, Barcelona Spain, 22-25 October 2019 . New Rochelle, NY, United States: Mary Anne Liebert. |
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2018 Journal Article Liposomal formulation of polyacrylate-peptide conjugate as a new vaccine candidate against cervical cancerKhongkow, Mattaka, Liu, Tzu-yu, Bartlett, Stacey, Hussein, Waleed M., Nevagi, Reshma, Jia, Zhongfan, Monteiro, Michael J., Wells, James, Ruktanonchai, Uracha Rungsardthong, Skwarczynski, Mariusz and Toth, Istvan (2018). Liposomal formulation of polyacrylate-peptide conjugate as a new vaccine candidate against cervical cancer. Precision Nanomedicine, 1 (3), 183-193. doi: 10.33218/prnano1(3).181003.1 |
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2018 Journal Article Cytokines, chemokines, and other biomarkers of response for checkpoint inhibitor therapy in skin cancerBridge, Jennifer A., Lee, James C., Daud, Adil, Wells, James W. and Bluestone, Jeffrey A. (2018). Cytokines, chemokines, and other biomarkers of response for checkpoint inhibitor therapy in skin cancer. Frontiers in Medicine, 5 (DEC) 351, 351. doi: 10.3389/fmed.2018.00351 |
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2018 Journal Article The role of CXCR3 and its chemokine ligands in skin disease and cancerKuo, Paula T., Zeng, Zhen, Salim, Nazhifah, Mattarollo, Stephen, Wells, James W. and Leggatt, Graham R. (2018). The role of CXCR3 and its chemokine ligands in skin disease and cancer. Frontiers in Medicine, 5 (SEP) 271, 271. doi: 10.3389/fmed.2018.00271 |
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2018 Journal Article An ex vivo human tumour assay reveals distinct patterns of EGFR trafficking in squamous cell carcinoma correlating to therapeutic outcomesJoseph, Shannon R., Gaffney, Daniel, Barry, Rachael, Hu, Lingbo, Banushi, Blerida, Wells, James W., Lambie, Duncan, Strutton, Geoff, Porceddu, Sandro V., Burmeister, Bryan, Leggatt, Graham R., Schaider, Helmut, Dolcetti, Riccardo, Frazer, Ian H., Saunders, Nicholas A., Foote, Matthew, Soyer, H. Peter and Simpson, Fiona (2018). An ex vivo human tumour assay reveals distinct patterns of EGFR trafficking in squamous cell carcinoma correlating to therapeutic outcomes. Journal of Investigative Dermatology, 139 (1), 213-223. doi: 10.1016/j.jid.2018.06.190 |
