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2015 Journal Article Discovery and characterization of a potent interleukin-6 binding peptide with neutralizing activity in vivoRanganath, Sheila, Bhandari, Ashok, Avitahl-Curtis, Nicole, McMahon, Jaimee, Wachtel, Derek, Zhang, Jenny, Leitheiser, Christopher, Bernier, Sylvie G., Liu, Guang, Tran, Tran T., Celino, Herodion, Tobin, Jenny, Jung, Joon, Zhao, Hong, Glen, Katie E., Graul, Chris, Griffin, Aliesha, Schairer, Wayne C., Higgins, Carolyn, Reza, Tammi L., Mowe, Eva, Rivers, Sam, Scott, Sonya, Monreal, Alex, Shea, Courtney, Bourne, Greg, Coons, Casey, Smith, Adaline, Tang, Kim ... Carlson, Kenneth E. (2015). Discovery and characterization of a potent interleukin-6 binding peptide with neutralizing activity in vivo. PLoS One, 10 (11) e0141330, 1-19. doi: 10.1371/journal.pone.0141330 |
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2013 Journal Article Isolation and structures of axistatins 1-3 from the Republic of Palau marine sponge Agelas axifera Hentschel(1)Pettit, George R., Tang, Yuping, Zhang, Qingwen, Bourne, Gregory T., Arm, Christoph A., Leet, John E., Knight, John C., Pettit, Robin K., Chapuis, Jean-Charles, Doubek, Dennis L., Ward, Franklin J., Weber, Christine and Hooper, John N. A. (2013). Isolation and structures of axistatins 1-3 from the Republic of Palau marine sponge Agelas axifera Hentschel(1). Journal of Natural Products, 76 (3), 420-424. doi: 10.1021/np300828y |
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2010 Journal Article Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D-2 synthasesChrist, Angelika N., Labzin, Larisa, Bourne, Gregory T., Fukunishi, Hirotada, Weber, Jane E., Sweet, Matthew J., Smythe, Mark L. and Flanagan, Jack U. (2010). Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D-2 synthases. Journal of Medicinal Chemistry, 53 (15), 5536-5548. doi: 10.1021/jm100194a |
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2010 Journal Article Synthesis of the phenylpyridal scaffold as a helical peptide mimeticBourne, Gregory T., Kuster, Daniel J. and Marshall, Garland R. (2010). Synthesis of the phenylpyridal scaffold as a helical peptide mimetic. Chemistry: A European Journal, 16 (28), 8439-8445. doi: 10.1002/chem.201000315 |
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2008 Journal Article Library of biphenyl privileged substructures using a safety-catch linker approachSeverinsen, Rune, Bourne, Gregory T., Tran, Tran T., Ankersen, Michael, Begtrup, Mikael and Smythe, Mark L. (2008). Library of biphenyl privileged substructures using a safety-catch linker approach. Journal of Combinatorial Chemistry, 10 (4), 557-566. doi: 10.1021/cc800006g |
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2008 Journal Article Cyclic tetrapeptides via the ring contraction strategy: Chemical techniques useful for their identificationHorton, D. A., Bourne, G. T., Coughlan, J., Kaiser, S. M., Jacobs, C. M., Jones, A., Ruhmann, A., Turner, J. Y. and Smythe, M. L. (2008). Cyclic tetrapeptides via the ring contraction strategy: Chemical techniques useful for their identification. Organic & Biomolecular Chemistry, 6 (8), 1386-1395. doi: 10.1039/b800464a |
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2007 Journal Article Conformational manifold of α-aminoisobutyric acid (Aib) containing alanine-Based tripeptides in aqueous solution explored by vibrational spectroscopy, electronic circular dichroism spectroscopy, and molecular dynamics simulationsSchweitzer-Stenner, Reinhard, Gonzales, Widalys, Bourne, Gregory T., Feng, Jianwen A. and Marshall, Garland R. (2007). Conformational manifold of α-aminoisobutyric acid (Aib) containing alanine-Based tripeptides in aqueous solution explored by vibrational spectroscopy, electronic circular dichroism spectroscopy, and molecular dynamics simulations. Journal of the American Chemical Society, 129 (43), 13095-13109. doi: 10.1021/ja0738430 |
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2006 Journal Article A gradient descent algorithm for minimizing amino acid coupling reactions when synthesizing cyclic-peptide librariesDarwen, PJ, Tran, TT, Bourne, GT, Nielson, JL and Smythe, ML (2006). A gradient descent algorithm for minimizing amino acid coupling reactions when synthesizing cyclic-peptide libraries. Combinatorial Chemistry & High Throughput Screening, 9 (7), 559-563. doi: 10.2174/138620706777935333 |
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2005 Journal Article A convenient method for synthesis of cyclic peptide librariesBourne, Gregory T, Nielson, Jonathon L, Coughlan, Justin F, Darwen, Paul, Campitelli, Marc R, Horton, Douglas A, Rhümann, Andreas, Love, Stephen G, Tran, Tran T and Smythe, Mark L (2005). A convenient method for synthesis of cyclic peptide libraries. Methods in molecular biology (Clifton, N.J.), 298, 151-165. doi: 10.1385/1-59259-877-3:151 |
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2005 Journal Article A versatile synthetic approach to peptidyl privileged structures using a "safety-catch" linkerHorton, Douglas A., Severinsen, Rune, Kofod-Hansen, Mikael, Bourne, Gregorty T. and Smythe, Mark L. (2005). A versatile synthetic approach to peptidyl privileged structures using a "safety-catch" linker. Journal of Combinatorial Chemistry, 7 (3), 421-435. doi: 10.1021/cc049829q |
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2005 Journal Article A safety catch linker for Fmoc-based assembly of constrained cyclic peptidesRavn, J, Bourne, GT and Smythe, ML (2005). A safety catch linker for Fmoc-based assembly of constrained cyclic peptides. Journal of Peptide Science, 11 (9), 572-578. doi: 10.1002/psc.651 |
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2005 Journal Article Topological side-chain classification of beta-turns: Ideal motifs for peptidomimetic developmentTran, TT, McKie, J, Meutermans, WDF, Bourne, GT, Andrews, PR and Smythe, ML (2005). Topological side-chain classification of beta-turns: Ideal motifs for peptidomimetic development. Journal of Computer-aided Molecular Design, 19 (8), 551-566. doi: 10.1007/s10822-005-9006-2 |
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2003 Journal Article The combinatorial synthesis of bicyclic privileged structures or privileged substructuresHorton, DA, Bourne, GT and Smythe, ML (2003). The combinatorial synthesis of bicyclic privileged structures or privileged substructures. Chemical Reviews, 103 (3), 893-930. doi: 10.1021/cr020033s |
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2003 Journal Article Difficult macrocyclizations: New strategies for synthesizing highly strained cyclic tetrapeptidesMeutermans, W., Bourne, G. T., Golding, S., Horton, D., Campitelli, M. R., Craik, D. J., Scanlon, M. J. and Smythe, M. L. (2003). Difficult macrocyclizations: New strategies for synthesizing highly strained cyclic tetrapeptides. Organic Letters, 5 (15), 2711-2714. doi: 10.1021/ol034907o |
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2002 Journal Article Exploring privileged structures: the combinatorial synthesis of cyclic peptidesHorton, D. A., Bourne, G. T. and Smythe, M. L. (2002). Exploring privileged structures: the combinatorial synthesis of cyclic peptides. Journal of Computer-aided Molecular Design, 16 (5-6), 415-431. doi: 10.1023/A:1020863921840 |
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2001 Journal Article The development and application of a novel safety-catch linker for BOC-based assembly of libraries of cyclic peptidesBourne, Gregory T., Golding, Simon W., McGeary, Ross P., Meutermans, Wim D. F., Jones, Alun, Marshall, Garland R., Alewood, Paul F. and Smythe, Mark L. (2001). The development and application of a novel safety-catch linker for BOC-based assembly of libraries of cyclic peptides. Journal of Organic Chemistry, 66 (23), 7706-7713. doi: 10.1021/jo010580y |
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2001 Journal Article Synthesis of a cyclic peptide library based on the somatostatin sequence using the backbone amide linker approachBourne, G.T., Golding, S., Meutermans, W. and Smythe, M.L. (2001). Synthesis of a cyclic peptide library based on the somatostatin sequence using the backbone amide linker approach. Letters in Peptide Science, 7 (6), 311-316. doi: 10.1023/A:1013057832044 |
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2000 Journal Article Synthesis of difficult cyclic peptides by inclusion of a novel photolabile auxiliary in a ring contraction strategyScolastico, C., Manzoni, L., Meutermans, W. D.F., Golding, S. W., Bourne, G. T., Miranda, L. P., Dooley, M. J., Alewood, P. F. and Smythe, M. L. (2000). Synthesis of difficult cyclic peptides by inclusion of a novel photolabile auxiliary in a ring contraction strategy. Chemtracts, 13 (7), 443-446. |
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2000 Journal Article Exploring privileged structures: The combinatorial synthesis of cyclic peptidesHorton, DA, Bourne, GT and Smythe, ML (2000). Exploring privileged structures: The combinatorial synthesis of cyclic peptides. Molecular Diversity, 5 (4), 289-304. doi: 10.1023/A:1021365402751 |
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1999 Journal Article The development of solid phase protocols for a backbone amide linker and its application to the Boc-based assembly of linear peptidesBourne, G. T., Meutermans, W. D. F. and Smythe, M. L. (1999). The development of solid phase protocols for a backbone amide linker and its application to the Boc-based assembly of linear peptides. Tetrahedron Letters, 40 (40), 7271-7274. doi: 10.1016/S0040-4039(99)01473-2 |
