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2022 Conference Publication Interaction between type 2 cytokine and inflammasome responses in the pathogenesis of obesity-associated asthmaPinkerton, J., Kim, R., Brown, A., Rae, B., Donovan, C., Mayall, J., Ali, M. K., Scott, H., Berthon, B., Baines, K., Starkey, M., Kermani, N., Guo, Y., Robertson, A., O'Neill, L., Adcock, , Cooper, M., Gibson, P., Wood, L., Hansbro, P. and Horvat, J. (2022). Interaction between type 2 cytokine and inflammasome responses in the pathogenesis of obesity-associated asthma. International Congress of the European-Respiratory-Society (ERS), Barcelona Spain, Sep 04-06, 2022. SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD. doi: 10.1183/13993003.congress-2022.871 |
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2020 Conference Publication Targeting the NLRP3 inflammasome as a novel approach to treat pulmonary hypertensionScott, T. E., Ung, V., Baliga, R. S., Robertson, A. A. B., Nold-Petry, C. A., Nold, M. F., Drummond, G. R., Hobbs, A. J. and Kemp-Harper, B. K. (2020). Targeting the NLRP3 inflammasome as a novel approach to treat pulmonary hypertension. International Conference of the American Thoracic Society, Electr Network, 2020. New York, NY, United States: American Thoracic Society. doi: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a3830 |
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2019 Conference Publication IL-5/IL-13 drive NLRP3 inflammasome-mediated, steroid-resistant AHR in a model of obesity-associated asthmaPinkerton, James, Kim, Richard, Brown, Alexandra, Rae, Brittany, Mayall, Jemma, Ali, Md. Khadem, Starkey, Malcolm, Robertson, Avril, Wood, Lisa, Cooper, Matthew, O'Neill, Luke, Hansbro, Philip and Horvat, Jay (2019). IL-5/IL-13 drive NLRP3 inflammasome-mediated, steroid-resistant AHR in a model of obesity-associated asthma. European Respiratory Society (ERS) International Congress, Madrid, Spain, 28 September-2 October 2019. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2019.pa3345 |
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2019 Conference Publication Inhibition of NLRP3 does not protect against photo-oxidative damage-induced retinal degenerationWooff, Yvette, Fernando, Nilisha, Wong, Josephine, Dietrich, Catherine, Aggio-Bruce, Riemke, Chu-Tan, Joshua Aaron, Doyle, Sarah, Robertson, Avril, Man, Si Ming and Natoli, Riccardo Carlo (2019). Inhibition of NLRP3 does not protect against photo-oxidative damage-induced retinal degeneration. Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Vancouver, Canada, 28 April - 2 May 2019. Rockville, MD, United States: Association for Research in Vision and Ophthalmology. |
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2017 Conference Publication High Fat Diet-Induced Obesity Promotes Steroid-Resistant Asthma Through An Nlrp3 Inflammasome-Dependent MechanismPinkerton, James, Kim, Richard, Mayall, Jemma, Ali, Md. Khadem, Starkey, Malcolm, Robertson, Avril, O'Neill, Luke, Cooper, Matthew, Hansbro, Philip and Horvat, Jay (2017). High Fat Diet-Induced Obesity Promotes Steroid-Resistant Asthma Through An Nlrp3 Inflammasome-Dependent Mechanism. HOBOKEN: WILEY. |
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2016 Conference Publication Targeting the NLRP3 inflammasome is a viable option for the treatment of pathogenic influenza virus infectionTate, M., Ong, J., Dowling, J., Robertson, A., Cooper, M. and Mansell, A. (2016). Targeting the NLRP3 inflammasome is a viable option for the treatment of pathogenic influenza virus infection. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL. |
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2016 Conference Publication Delayed inhibition of the NLRP3 inflammasome during pathogenic influenza A virus infection in mice reduces disease severity and prolongs survivalTate, M., Pinar, A., Dowling, J., McAuley, J., Robertson, A., Cooper, M. and Mansell, A. (2016). Delayed inhibition of the NLRP3 inflammasome during pathogenic influenza A virus infection in mice reduces disease severity and prolongs survival. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL. |
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2016 Conference Publication Autocrine NLPR3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-γ in CD4+ T cellsWest, Erin E., Arbore, Giuseppina, Robertson, Avril A.B., Klos, Andreas, Woodruff, Trent M., O’Neill, Luke A., Coll, Rebecca C., Sher, Alan, Leonard, Warren J., Köhl, Jörg, Monk, Pete, Cooper, Matthew A., Afzali, Behdad, Lachmann, Helen J., Cope, Andrew P., Mayer-Barber, Katrin and Kemper, Claudia (2016). Autocrine NLPR3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-γ in CD4+ T cells. Immunology 2016™ Meeting, Seattle, WA United States, 13 - 17 May 2016. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.196.supp.58.6 |
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2016 Conference Publication The NLRP3 inflammasome negatively regulates type 2 immunity to gastrointestinal helminth infectionAlhallaf, R., Agha, Z., Miller, C. M., Robertson, A. A., Dent, L. A., Cooper, M. A., Masters, S. L., Smith, N. C., Loukas, A. and Giacomin, P. R. (2016). The NLRP3 inflammasome negatively regulates type 2 immunity to gastrointestinal helminth infection. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH Verlag. doi: 10.1002/eji.201670200 |
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2016 Conference Publication Autocrine NLPR3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-gamma in CD4(+) T cellsWest, Erin E., Arbore, Giuseppina, Robertson, Avril A. B., Klos, Andreas, Woodruff, Trent M., O'Neill, Luke A., Coll, Rebecca C., Sher, Alan, Leonard, Warren J., Koehl, Joerg, Monk, Pete, Cooper, Matthew A., Afzali, Behdad, Lachmann, Helen J., Cope, Andrew P., Mayer-Barber, Katrin and Kemper, Claudia (2016). Autocrine NLPR3 inflammasome activity is critical to normal adaptive immunity via regulation of IFN-gamma in CD4(+) T cells. Annual Meeting of the American Association of Immunologists (AAI), Seattle, WA, United States, 13-17 May 2016. Bethesda, MD, United States: American Association of Immunologists. |
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2016 Conference Publication Role of inflammation, vasoconstriction and oxidative stress in the enhanced pressor response to angiotensin II in aged miceDinh, Q. N., Drummond, G. R., Kemp-Harper, B. K., Diep, H., Robertson, A. A. B., Cooper, M. A., Sobey, C. G. and Chrissobolis, S. (2016). Role of inflammation, vasoconstriction and oxidative stress in the enhanced pressor response to angiotensin II in aged mice. 37th Annual Scientific Meeting of The High Blood Pressure Research Council Of Australia, Melbourne, VIC, Australia, 2-4 December 2015. Philadelphia, PA, United States: Lippincott Williams & Wilkins. doi: 10.1161/HYP.0000000000000042 |
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2016 Conference Publication NLRP3 inflammasome-mediated, IL-1 beta-dependent inflammatory responses drive severe, steroid-insensitive asthmaKim, R., Pinkerton, J., Essilfie, A., Robertson, A., Baines, K., Mayall, J., Starkey, M., Wark, P., Gibson, P., O'Neill, L., Cooper, M., Horvat, J. and Hansbro, P. (2016). NLRP3 inflammasome-mediated, IL-1 beta-dependent inflammatory responses drive severe, steroid-insensitive asthma. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Perth, WA, Australia, 1–6 April 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.12754_11 |
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2016 Conference Publication Evidence against a role for NLRP3-driven inflammation in the db/db mouse model of type 2 diabetesKammoun, H. L., Allen, T. L., Henstridge, D. C., Barre, S., Coll, R. C., Butler, M. S., Roberston, A. A. B., O'Neill, L. A., Murphy, A. J., Cooper, M. A. and Febbraio, M. A. (2016). Evidence against a role for NLRP3-driven inflammation in the db/db mouse model of type 2 diabetes. International Congress of Immunology (ICI), Melbourne, VIC, Australia, 21-26 August 2016. Weinheim, Germany: Wiley - VCH Verlag. doi: 10.1002/eji.201670200 |
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2016 Conference Publication Nlrp3 Inflammasome-Mediated, Il-1 beta-Dependent Inflammatory Responses Drive Severe, Steroid-Insensitive AsthmaKim, R. Y., Pinkerton, J. W., Essilfie, A. -T., Robertson, A. A., Baines, K. J., Mayall, J. R., Starkey, M. R., Wark, P. A., Gibson, P. G., O'Neill, L. A., Cooper, M. A., Horvat, J. C. and Hansbro, P. M. (2016). Nlrp3 Inflammasome-Mediated, Il-1 beta-Dependent Inflammatory Responses Drive Severe, Steroid-Insensitive Asthma. International Conference of the American Thoracic Society (ATS), San Francisco, California, 13-18 May 2016 . New York, NY, United States: American Thoracic Society. |
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2015 Conference Publication An optimized whole blood assay measuring expression and activity of NLRP3-, NLRC4 and AIM2-inflammasomesGrinstein, L., Luksch, H., Robertson, A. A. B., Cooper, M. A., Winkler, S. and Rösen-Wolff, A. (2015). An optimized whole blood assay measuring expression and activity of NLRP3-, NLRC4 and AIM2-inflammasomes. 8th International Congress of Familial Mediterranean Fever and Systemic Autoinflammatory Diseases, Dresden, Germany, 30 September - 3 October 2015. BMC. doi: 10.1186/1546-0096-13-S1-O51 |
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2015 Conference Publication Selective inhibition of the NLRP3 inflammasome dose-dependently reduces infarct size and preserves cardiac function in a porcine model of myocardial infarctionVan Hout, G. P. J., Bosch, L., Ellenbroek, G. H. J. M., Cooper, M., Van Solinge, W. W., De Jager, S. C. A., Robertson, A., Pasterkamp, G. and Hoefer, I. E. (2015). Selective inhibition of the NLRP3 inflammasome dose-dependently reduces infarct size and preserves cardiac function in a porcine model of myocardial infarction. Congress of the European Society of Cardiology (ESC), London, United Kingdom, 29 August-2 September 2015. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/eurheartj/ehv400 |
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2015 Conference Publication Activation of Redox-Sensitive Inflammasomes Underlies the Biological Phenotype of Myelodysplastic SyndromesBasiorka, A., Mcgraw, K., Eksioglu, E., Chen, X., Johnson, J., Padron, E., Komrokji, R., Sokol, L., Coll, R., O'Neill, L., Cooper, M., Robertson, A., Wei, S. and List, A. (2015). Activation of Redox-Sensitive Inflammasomes Underlies the Biological Phenotype of Myelodysplastic Syndromes. 13th International Symposium on Myelodysplastic Syndromes (MDS), Washington DC, United States, Apr 29-May 02, 2015. Kidlington, Oxford, United Kingdom: Pergamon Press. doi: 10.1016/S0145-2126(15)30033-3 |
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2015 Conference Publication Novel compound cytokine release inhibitory drug 3 (CRID3) inhibits the NLRP3 inflammasome in rheumatoid arthritisMcGarry, T., Coll, R.C., Robertson, A.A.B., Cooper, M.A., O’Neill, L.A., Veale, D.J. and Fearon, U. (2015). Novel compound cytokine release inhibitory drug 3 (CRID3) inhibits the NLRP3 inflammasome in rheumatoid arthritis. 35th European Workshop for Rheumatology Research, Budapest, Hungary, 5-7 March 2015. London, United Kingdom: BMJ Group. doi: 10.1136/annrheumdis-2015-207259.144 |
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2015 Conference Publication The effect of novel compound MCC950 On the NLRP3 inflammasome in the RA jointMcGarry, T., Robertson, A. A., Orr, C., Coll, R. C., Cooper, M. A., O'Neill, L. A., Veale, D. J. and Fearon, U. (2015). The effect of novel compound MCC950 On the NLRP3 inflammasome in the RA joint. Annual European Congress of Rheumatology, Rome, Italy, 10-13 July 2015. London, United Kingdom: BMJ Group. doi: 10.1136/annrheumdis-2015-eular.3985 |
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2015 Conference Publication Blocking the NLRP3 inflammasome prevents inflammatory recruitment and fibrotic progression in experimental NASHMridha, Auvro R., Wree, Alexander, Robertson, Avril A., Teoh, Narci C., Cooper, Matthew A., Feldstein, Ariel E. and Farrell, Geoffrey C. (2015). Blocking the NLRP3 inflammasome prevents inflammatory recruitment and fibrotic progression in experimental NASH. 66th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), San Francisco, CA, United States, 13-17 November 2015. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/hep.28175 |
