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2024

Journal Article

Unraveling the origins of pathogenic CXCL13<sup>+</sup> helper T&nbsp;cells in systemic lupus erythematosus

Nettelfield, Sam and Chen, Zhian (2024). Unraveling the origins of pathogenic CXCL13+ helper T&nbsp;cells in systemic lupus erythematosus. Immunology and Cell Biology, 102 (9), 757-759. doi: 10.1111/imcb.12818

Unraveling the origins of pathogenic CXCL13<sup>+</sup> helper T&nbsp;cells in systemic lupus erythematosus

2024

Journal Article

Author Correction: Selenium–GPX4 axis protects follicular helper T cells from ferroptosis

Yao, Yin, Chen, Zhian, Zhang, Hao, Chen, Cailing, Zeng, Ming, Yunis, Joseph, Wei, Yunbo, Wan, Yanmin, Wang, Naiqi, Zhou, Mingzhe, Qiu, Chao, Zeng, Qunxiong, Ong, Hong Sheng, Wang, Hao, Makota, Fadzai Victor, Yang, Yang, Yang, Zhaohui, Wang, Nan, Deng, Jun, Shen, Chao, Xia, Yan, Yuan, Lin, Lian, Zhaoqin, Deng, Yike, Guo, Cuilian, Huang, Ao, Zhou, Pengcheng, Shi, Haibo, Zhang, Weitian ... Yu, Di (2024). Author Correction: Selenium–GPX4 axis protects follicular helper T cells from ferroptosis. Nature Immunology, 25 (9), 1764-1764. doi: 10.1038/s41590-024-01949-z

Author Correction: Selenium–GPX4 axis protects follicular helper T cells from ferroptosis

2024

Journal Article

The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening

Patrick, Ralph, Naval-Sanchez, Marina, Deshpande, Nikita, Huang, Yifei, Zhang, Jingyu, Chen, Xiaoli, Yang, Ying, Tiwari, Kanupriya, Esmaeili, Mohammadhossein, Tran, Minh, Mohamed, Amin R., Wang, Binxu, Xia, Di, Ma, Jun, Bayliss, Jacqueline, Wong, Kahlia, Hun, Michael L., Sun, Xuan, Cao, Benjamin, Cottle, Denny L., Catterall, Tara, Barzilai-Tutsch, Hila, Troskie, Robin-Lee, Chen, Zhian, Wise, Andrea F., Saini, Sheetal, Soe, Ye Mon, Kumari, Snehlata, Sweet, Matthew J. ... Nefzger, Christian M. (2024). The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening. Cell Metabolism, 36 (8), 1858-1881.e23. doi: 10.1016/j.cmet.2024.06.006

The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening

2023

Journal Article

Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation

Chen, Zhian, Cui, Yanfang, Yao, Yin, Liu, Bo, Yunis, Joseph, Gao, Xin, Wang, Naiqi, Cañete, Pablo F., Tuong, Zewen Kelvin, Sun, Hongjian, Wang, Hao, Yang, Siling, Wang, Runli, Leong, Yew Ann, Simon Davis, David, Qin, Jiahuan, Liang, Kaili, Deng, Jun, Wang, Conan K., Huang, Yen-Hua, Roco, Jonathan A., Nettelfield, Sam, Zhu, Huaming, Xu, Huajun, Yu, Zhijia, Craik, David, Liu, Zheng, Qi, Hai, Parish, Christopher and Yu, Di (2023). Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation. Science immunology, 8 (80) eadd1728, 1-17. doi: 10.1126/sciimmunol.add1728

Heparan sulfate regulates IL-21 bioavailability and signal strength that control germinal center B cell selection and differentiation

2022

Journal Article

Context-dependent regulation of follicular helper T cell survival

Chen, Zhian, Wang, Naiqi, Yao, Yin and Yu, Di (2022). Context-dependent regulation of follicular helper T cell survival. Trends in Immunology, 43 (4), 309-321. doi: 10.1016/j.it.2022.02.002

Context-dependent regulation of follicular helper T cell survival

2022

Journal Article

Evolution of γ chain cytokines: mechanisms, methods and applications

Antczak, Magdalena, Cañete, Pablo F., Chen, Zhian, Belle, Clémence and Yu, Di (2022). Evolution of γ chain cytokines: mechanisms, methods and applications. Computational and Structural Biotechnology Journal, 20, 4746-4755. doi: 10.1016/j.csbj.2022.08.050

Evolution of γ chain cytokines: mechanisms, methods and applications

2022

Journal Article

Longevity of vaccine protection: immunological mechanism, assessment methods, and improving strategy

Chen, Zhian, Gao, Xin and Yu, Di (2022). Longevity of vaccine protection: immunological mechanism, assessment methods, and improving strategy. View, 3 (1) 20200103, 20200103. doi: 10.1002/viw.20200103

Longevity of vaccine protection: immunological mechanism, assessment methods, and improving strategy

2021

Journal Article

Author Correction: Selenium–GPX4 axis protects follicular helper T cells from ferroptosis

Yao, Yin, Chen, Zhian, Zhang, Hao, Chen, Cailing, Zeng, Ming, Yunis, Joseph, Wei, Yunbo, Wan, Yanmin, Wang, Naiqi, Zhou, Mingzhe, Qiu, Chao, Zeng, Qunxiong, Ong, Hong Sheng, Wang, Hao, Makota, Fadzai Victor, Yang, Yang, Yang, Zhaohui, Wang, Nan, Deng, Jun, Shen, Chao, Xia, Yan, Yuan, Lin, Lian, Zhaoqin, Deng, Yike, Guo, Cuilian, Huang, Ao, Zhou, Pengcheng, Shi, Haibo, Zhang, Weitian ... Yu, Di (2021). Author Correction: Selenium–GPX4 axis protects follicular helper T cells from ferroptosis. Nature Immunology, 22 (12), 1599-1599. doi: 10.1038/s41590-021-01063-4

Author Correction: Selenium–GPX4 axis protects follicular helper T cells from ferroptosis

2021

Journal Article

Supranutritional selenium suppresses ROS‐induced generation of RANKL‐expressing osteoclastogenic CD4 + T cells and ameliorates rheumatoid arthritis

Qin, Jiahuan, Huang, Xia, Wang, Naiqi, Zhou, Pengcheng, Zhang, Hao, Chen, Zhian, Liang, Kaili, Gong, Dongcheng, Zeng, Qunxiong, Niu, Peng, Chen, Anping, Yuan, Lin, Yang, Zhaohui, Su, Linchong, Shen, Nan, Deng, Jun and Yu, Di (2021). Supranutritional selenium suppresses ROS‐induced generation of RANKL‐expressing osteoclastogenic CD4 + T cells and ameliorates rheumatoid arthritis. Clinical & Translational Immunology, 10 (9) e1338, e1338. doi: 10.1002/cti2.1338

Supranutritional selenium suppresses ROS‐induced generation of RANKL‐expressing osteoclastogenic CD4 + T cells and ameliorates rheumatoid arthritis

2021

Journal Article

Selenium–GPX4 axis protects follicular helper T cells from ferroptosis

Yao, Yin, Chen, Zhian, Zhang, Hao, Chen, Cailing, Zeng, Ming, Yunis, Joseph, Wei, Yunbo, Wan, Yanmin, Wang, Naiqi, Zhou, Mingzhe, Qiu, Chao, Zeng, Qunxiong, Ong, Hong Sheng, Wang, Hao, Makota, Fadzai Victor, Yang, Yang, Yang, Zhaohui, Wang, Nan, Deng, Jun, Shen, Chao, Xia, Yan, Yuan, Lin, Lian, Zhaoqin, Deng, Yike, Guo, Cuilian, Huang, Ao, Zhou, Pengcheng, Shi, Haibo, Zhang, Weitian ... Yu, Di (2021). Selenium–GPX4 axis protects follicular helper T cells from ferroptosis. Nature Immunology, 22 (9), 1127-1139. doi: 10.1038/s41590-021-00996-0

Selenium–GPX4 axis protects follicular helper T cells from ferroptosis

2021

Journal Article

Sustained low-dose interleukin-2 therapy alleviates pathogenic humoral immunity via elevating the Tfr/Tfh ratio in lupus

Liang, Kaili, He, Jing, Wei, Yunbo, Zeng, Qunxiong, Gong, Dongcheng, Qin, Jiahuan, Ding, Huihua, Chen, Zhian, Zhou, Ping, Niu, Peng, Chen, Qian, Ding, Chenguang, Lu, Liangjing, Chen, Xiao-Xiang, Li, Zhanguo, Shen, Nan, Yu, Di and Deng, Jun (2021). Sustained low-dose interleukin-2 therapy alleviates pathogenic humoral immunity via elevating the Tfr/Tfh ratio in lupus. Clinical and Translational Immunology, 10 (6) e1293, e1293. doi: 10.1002/cti2.1293

Sustained low-dose interleukin-2 therapy alleviates pathogenic humoral immunity via elevating the Tfr/Tfh ratio in lupus

2021

Journal Article

The metabolic hormone leptin promotes the function of TFH cells and supports vaccine responses

Deng, Jun, Chen, Qian, Chen, Zhian, Liang, Kaili, Gao, Xin, Wang, Xiaohui, Makota, Fadzai V., Ong, Hong Sheng, Wan, Yanmin, Luo, Kaiming, Gong, Dongcheng, Yu, Xiang, Camuglia, Sarina, Zeng, Qunxiong, Zhou, Tao, Xue, Feng, He, Jing, Wei, Yunbo, Xiao, Fan, Ma, Jianyang, Hill, Danika L., Pierson, Wim, Nguyen, Thi H. O., Zhou, Haibo, Wang, Yan, Shen, Wei, Sun, Lingyun, Li, Zhanguo, Xia, Qiang ... Yu, Di (2021). The metabolic hormone leptin promotes the function of TFH cells and supports vaccine responses. Nature Communications, 12 (1) 3073, 3073. doi: 10.1038/s41467-021-23220-x

The metabolic hormone leptin promotes the function of TFH cells and supports vaccine responses

2021

Journal Article

High levels of soluble CD25 in COVID‐19 severity suggest a divergence between anti‐viral and pro‐inflammatory T‐cell responses

Xie, Min, Yunis, Joseph, Yao, Yin, Shi, Jing, Yang, Yang, Zhou, Pengcheng, Liang, Kaili, Wan, Yanmin, Mehdi, Ahmed, Chen, Zhian, Wang, Naiqi, Xu, Shuyun, Zhou, Min, Yu, Muqing, Wang, Ke, Tao, Yu, Zhou, Ying, Li, Xiaochen, Liu, Xiansheng, Yu, Xiao, Wei, Yunbo, Liu, Zheng, Sprent, Jonathan and Yu, Di (2021). High levels of soluble CD25 in COVID‐19 severity suggest a divergence between anti‐viral and pro‐inflammatory T‐cell responses. Clinical & Translational Immunology, 10 (2) e1251, e1251. doi: 10.1002/cti2.1251

High levels of soluble CD25 in COVID‐19 severity suggest a divergence between anti‐viral and pro‐inflammatory T‐cell responses

2020

Journal Article

CD23 expression on switched memory B cells bridges T-B cell interaction in allergic rhinitis

Yao, Yin, Wang, Nan, Chen, Cai-Ling, Pan, Li, Wang, Zhi-Chao, Yunis, Joseph, Chen, Zhi-An, Zhang, Yu, Hu, Si-Tao, Xu, Xiao-Yan, Zhu, Rong-Fei, Yu, Di and Liu, Zheng (2020). CD23 expression on switched memory B cells bridges T-B cell interaction in allergic rhinitis. Allergy, 75 (10), 1-14. doi: 10.1111/all.14288

CD23 expression on switched memory B cells bridges T-B cell interaction in allergic rhinitis

2019

Journal Article

An optimized method to differentiate mouse follicular helper T cells in vitro

Gao, Xin, Wang, Hao, Chen, Zhian, Zhou, Pengcheng and Yu, Di (2019). An optimized method to differentiate mouse follicular helper T cells in vitro. Cellular and Molecular Immunology, 17 (7), 779-781. doi: 10.1038/s41423-019-0329-7

An optimized method to differentiate mouse follicular helper T cells in vitro

2019

Journal Article

Corrigendum: signal transducer and activator of transcription 3 hyperactivation associates with follicular helper t cell differentiation and disease activity in rheumatoid arthritis (Front. Immunol., (2018), 9, 10.3389/fimmu.2018.01226)

Deng, Jun, Fan, Chaofan, Gao, Xin, Zeng, Qunxiong, Guo, Ruru, Wei, Yunbo, Chen, Zhian, Chen, Yanan, Gong, Dongcheng, Feng, Jia, Xia, Yan, Xiang, Shifei, Gong, Shushi, Yuan, Lin, Shen, Wei, Shen, Wenyan, Lin, Lin, Jiang, Ting, He, Dongyi, Lu, Liangjing, Chen, Xiaoxiang and Yu, Di (2019). Corrigendum: signal transducer and activator of transcription 3 hyperactivation associates with follicular helper t cell differentiation and disease activity in rheumatoid arthritis (Front. Immunol., (2018), 9, 10.3389/fimmu.2018.01226). Frontiers in Immunology, 10 (AUG) 2008. doi: 10.3389/fimmu.2019.02008

Corrigendum: signal transducer and activator of transcription 3 hyperactivation associates with follicular helper t cell differentiation and disease activity in rheumatoid arthritis (Front. Immunol., (2018), 9, 10.3389/fimmu.2018.01226)

2018

Journal Article

Signal transducer and activator of transcription 3 hyperactivation associates with follicular helper T cell differentiation and disease activity in rheumatoid arthritis

Deng, Jun, Fan, Chaofan, Gao, Xin, Zeng, Qunxiong, Guo, Ruru, Wei, Yunbo, Chen, Zhian, Chen, Yanan, Gong, Dongcheng, Feng, Jia, Xia, Yan, Xiang, Shifei, Gong, Shushi, Yuan, Lin, Shen, Wei, Shen, Wenyan, Lin, Lin, Jiang, Ting, He, Dongyi, Lu, Liangjing, Chen, Xiaoxiang and Yu, Di (2018). Signal transducer and activator of transcription 3 hyperactivation associates with follicular helper T cell differentiation and disease activity in rheumatoid arthritis. Frontiers in Immunology, 9 (JUN) 1226, 1-11. doi: 10.3389/fimmu.2018.01226

Signal transducer and activator of transcription 3 hyperactivation associates with follicular helper T cell differentiation and disease activity in rheumatoid arthritis

2013

Journal Article

Efficient production of recombinant IL-21 proteins for pre-clinical studies by a two-step dilution refolding method

Chen, Zhian, Cui, Yanfang, Leong, Yew Ann, Beddoe, Travis and Yu, Di (2013). Efficient production of recombinant IL-21 proteins for pre-clinical studies by a two-step dilution refolding method. International Immunopharmacology, 16 (3), 376-381. doi: 10.1016/j.intimp.2013.02.017

Efficient production of recombinant IL-21 proteins for pre-clinical studies by a two-step dilution refolding method