2021 Journal Article Metaproteomic sample preparation methods bias the recovery of host and microbial proteins according to taxa and cellular compartmentGavin, Patrick G., Wong, Justin, Loo, Dorothy, Zipris, Danny, Hill, Michelle M. and Hamilton-Williams, Emma E. (2021). Metaproteomic sample preparation methods bias the recovery of host and microbial proteins according to taxa and cellular compartment. Journal of Proteomics, 240 104219, 104219. doi: 10.1016/j.jprot.2021.104219 |
2021 Journal Article A triple threat? The role of diet, nutrition, and the microbiota in T1D pathogenesisHamilton-Williams, Emma E., Lorca, Graciela L., Norris, Jill M. and Dunne, Jessica L. (2021). A triple threat? The role of diet, nutrition, and the microbiota in T1D pathogenesis. Frontiers in Nutrition, 8 600756, 600756. doi: 10.3389/fnut.2021.600756 |
2021 Journal Article An acetate‐yielding diet imprints an immune and anti‐microbial programme against enteric infectionYap, Yu Anne, McLeod, Keiran H., McKenzie, Craig I., Gavin, Patrick G., Davalos‐Salas, Mercedes, Richards, James L., Moore, Robert J., Lockett, Trevor J., Clarke, Julie M., Eng, Vik Ven, Pearson, Jaclyn S., Hamilton‐Williams, Emma E., Mackay, Charles R. and Mariño, Eliana (2021). An acetate‐yielding diet imprints an immune and anti‐microbial programme against enteric infection. Clinical and Translational Immunology, 10 (1) e1233, e1233. doi: 10.1002/cti2.1233 |
2021 Journal Article Proinsulin‐specific T‐cell responses correlate with estimated c‐peptide and predict partial remission duration in type 1 diabetesMusthaffa, Yassmin, Hamilton‐Williams, Emma E, Nel, Hendrik J., Bergot, Anne‐Sophie, Mehdi, Ahmed M., Harris, Mark and Thomas, Ranjeny (2021). Proinsulin‐specific T‐cell responses correlate with estimated c‐peptide and predict partial remission duration in type 1 diabetes. Clinical & Translational Immunology, 10 (7) e1315, e1315. doi: 10.1002/cti2.1315 |
2020 Journal Article Optimization of a method to detect autoantigen-specific t-cell responses in type 1 diabetesMusthaffa, Yassmin, Nel, Hendrik J., Ramnoruth, Nishta, Patel, Swati, Hamilton-Williams, Emma E., Harris, Mark and Thomas, Ranjeny (2020). Optimization of a method to detect autoantigen-specific t-cell responses in type 1 diabetes. Frontiers in Immunology, 11 587469, 587469. doi: 10.3389/fimmu.2020.587469 |
2020 Journal Article A Question of Tolerance—Antigen-Specific Immunotherapy for Type 1 DiabetesLoaiza Naranjo, Jeniffer D., Bergot, Anne-Sophie, Buckle, Irina and Hamilton-Williams, Emma E. (2020). A Question of Tolerance—Antigen-Specific Immunotherapy for Type 1 Diabetes. Current Diabetes Reports, 20 (12) 70, 70. doi: 10.1007/s11892-020-01363-3 |
2020 Journal Article Regulatory T cells induced by single-peptide liposome immunotherapy suppress islet-Specific T cell responses to multiple antigens and protect from autoimmune diabetesBergot, Anne-Sophie, Buckle, Irina, Cikaluru, Sumana, Naranjo, Jennifer Loaiza, Wright, Casey Maree, Zheng, Guoliang, Talekar, Meghna, Hamilton-Williams, Emma E. and Thomas, Ranjeny (2020). Regulatory T cells induced by single-peptide liposome immunotherapy suppress islet-Specific T cell responses to multiple antigens and protect from autoimmune diabetes. Journal of Immunology, 204 (7), ji1901128-1797. doi: 10.4049/jimmunol.1901128 |
2019 Journal Article Early-life factors contributing to type 1 diabetesCraig, Maria E., Kim, Ki Wook, Isaacs, Sonia R., Penno, Megan A., Hamilton-Williams, Emma E., Couper, Jennifer J. and Rawlinson, William D. (2019). Early-life factors contributing to type 1 diabetes. Diabetologia, 62 (10), 1823-1834. doi: 10.1007/s00125-019-4942-x |
2019 Journal Article The gut microbiota in type 1 diabetes: friend or foe?Gavin, Patrick G. and Hamilton-Williams, Emma E. (2019). The gut microbiota in type 1 diabetes: friend or foe?. Current Opinion in Endocrinology, Diabetes and Obesity, 26 (4), 207-212. doi: 10.1097/MED.0000000000000483 |
2018 Journal Article Early-life exposure to gut microbiota from disease protected mice does not impact disease outcome in type 1 diabetes susceptible NOD miceMullaney, Jane A., Stephens, Juliette E., Geeling, Brooke E. and Hamilton-Williams, Emma E. (2018). Early-life exposure to gut microbiota from disease protected mice does not impact disease outcome in type 1 diabetes susceptible NOD mice. Immunology and Cell Biology, 97 (1), 97-103. doi: 10.1111/imcb.12201 |
2018 Journal Article Correction to: Type 1 diabetes susceptibility alleles are associated with distinct alterations in the gut microbiotaMullaney, Jane A., Stephens, Juliette E., Costello, Mary-Ellen, Fong, Cai, Geeling, Brooke E., Gavin, Patrick G., Wright, Casey M., Spector, Timothy D., Brown, Matthew A. and Hamilton-Williams, Emma E. (2018). Correction to: Type 1 diabetes susceptibility alleles are associated with distinct alterations in the gut microbiota. Microbiome, 6 (1), 51. doi: 10.1186/s40168-018-0438-z |
Featured 2018 Journal Article A peripheral blood transcriptomic signature predicts autoantibody development in infants at risk of type 1 diabetesMehdi, Ahmed M., Hamilton-Williams, Emma E., Cristino, Alexandre, Ziegler, Anette, Bonifacio, Ezio, Le Cao, Kim-Anh, Harris, Mark and Thomas, Ranjeny (2018). A peripheral blood transcriptomic signature predicts autoantibody development in infants at risk of type 1 diabetes. JCI Insight, 3 (5) e98212. doi: 10.1172/jci.insight.98212 |
2017 Journal Article CD11a/ICAM-1 blockade combined with IL-2 targeting therapy causes a paradoxical acceleration of type 1 diabetesBrenu, Ekua W., Bartley, Timothy J., Wright, Casey M. and Hamilton-Williams, Emma E. (2017). CD11a/ICAM-1 blockade combined with IL-2 targeting therapy causes a paradoxical acceleration of type 1 diabetes. Immunology and Cell Biology, 95 (9), 803-813. doi: 10.1038/icb.2017.49 |
2017 Journal Article Antigen presenting cell-targeted proinsulin expression converts insulin-specific CD8+ T-cell priming to tolerance in autoimmune-prone NOD miceReeves, Peta L. S., Rudraraju, Rajeev, Wong, F. Susan, Hamilton-Williams, Emma E. and Steptoe, Raymond J. (2017). Antigen presenting cell-targeted proinsulin expression converts insulin-specific CD8+ T-cell priming to tolerance in autoimmune-prone NOD mice. European Journal of Immunology, 47 (9), 1550-1561. doi: 10.1002/eji.201747089 |
2017 Journal Article APC-targeted proinsulin expression inactivates insulin-specific memory CD8+ T cells in NOD miceReeves, Peta L. S., Rudraraju, Rajeev, Liu, Xiao, Wong, F. Susan, Hamilton-Williams, Emma E. and Steptoe, Raymond J. (2017). APC-targeted proinsulin expression inactivates insulin-specific memory CD8+ T cells in NOD mice. Immunology and Cell Biology, 95 (9), 765-774. doi: 10.1038/icb.2017.48 |
2016 Journal Article Maintenance of peripheral tolerance to islet antigensHamilton-Williams, Emma E., Bergot, Anne-Sophie, Reeves, Peta L. S and Steptoe, Raymond J. (2016). Maintenance of peripheral tolerance to islet antigens. Journal of Autoimmunity, 72, 118-125. doi: 10.1016/j.jaut.2016.05.009 |
2016 Journal Article Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic miceJames, Cini R., Buckle, Irina, Muscate, Franziska, Otsuka, Masayuki, Nakao, Mari, Oon, Jack S. H., Steptoe, Raymond J., Thomas, Ranjeny and Hamilton-Williams, Emma E. (2016). Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic mice. Immunology and Cell Biology, 94 (5), 509-519. doi: 10.1038/icb.2016.7 |
2015 Journal Article Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetesPang, Dimeng, Irvine, Katharine M., Mehdi, Ahmed M., Thomas, Helen E., Harris, Mark, Hamilton-Williams, Emma E. and Thomas, Ranjeny (2015). Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes. Clinical and Translational Immunology, 4 (8) e41, e41.1-e41.9. doi: 10.1038/cti.2015.17 |
2013 Journal Article Fine mapping of type 1 diabetes regions Idd9.1 and Idd9.2 reveals genetic complexityHamilton-Williams, Emma E., Rainbow, Daniel B., Cheung, Jocelyn, Christensen, Mikkel, Lyons, Paul A., Peterson, Laurence B., Steward, Charles A., Sherman, Linda A. and Wicker, Linda S. (2013). Fine mapping of type 1 diabetes regions Idd9.1 and Idd9.2 reveals genetic complexity. Mammalian Genome, 24 (9-10), 358-375. doi: 10.1007/s00335-013-9466-y |
2013 Journal Article Genetic interactions among Idd3, Idd5.1, Idd5.2, and Idd5.3 protective loci in the nonobese diabetic mouse model of type 1 diabetesLin, Xiaotian, Hamilton-Williams, Emma E., Rainbow, Daniel B., Hunter, Kara M., Dai, Yang D., Cheung, Jocelyn, Peterson, Laurence B., Wicker, Linda S. and Sherman, Linda A. (2013). Genetic interactions among Idd3, Idd5.1, Idd5.2, and Idd5.3 protective loci in the nonobese diabetic mouse model of type 1 diabetes. Journal of Immunology, 190 (7), 3109-3120. doi: 10.4049/jimmunol.1203422 |