|
2024 Journal Article Leveraging spatial omics for the development of precision sarcoma treatmentsTu, Cui, Kulasinghe, Arutha, Barbour, Andrew and Souza-Fonseca-Guimaraes, Fernando (2024). Leveraging spatial omics for the development of precision sarcoma treatments. Trends in Pharmacological Sciences, 45 (2), 134-144. doi: 10.1016/j.tips.2023.12.006 |
|
2024 Journal Article Inhibition of Aurora B kinase (AURKB) enhances the effectiveness of 5-fluorouracil chemotherapy against colorectal cancer cellsShah, Esha T., Molloy, Christopher, Gough, Madeline, Kryza, Thomas, Samuel, Selwin G., Tucker, Amos, Bhatia, Maneet, Ferguson, Genevieve, Heyman, Rebecca, Vora, Shivam, Monkman, James, Bolderson, Emma, Kulasinghe, Arutha, He, Yaowu, Gabrielli, Brian, Hooper, John D., Richard, Derek J., O’Byrne, Kenneth J. and Adams, Mark N. (2024). Inhibition of Aurora B kinase (AURKB) enhances the effectiveness of 5-fluorouracil chemotherapy against colorectal cancer cells. British Journal of Cancer, 130 (7), 1196-1205. doi: 10.1038/s41416-024-02584-z |
|
2024 Journal Article standR: spatial transcriptomic analysis for GeoMx DSP dataLiu, Ning, Bhuva, Dharmesh D, Mohamed, Ahmed, Bokelund, Micah, Kulasinghe, Arutha, Tan, Chin Wee and Davis, Melissa J (2024). standR: spatial transcriptomic analysis for GeoMx DSP data. Nucleic Acids Research, 52 (1) e2, 1-11. doi: 10.1093/nar/gkad1026 |
|
2023 Journal Article Metabolomics at the tumor microenvironment interface: decoding cellular conversationsBerrell, Naomi, Sadeghirad, Habib, Blick, Tony, Bidgood, Charles, Leggatt, Graham R., O'Byrne, Ken and Kulasinghe, Arutha (2023). Metabolomics at the tumor microenvironment interface: decoding cellular conversations. Medicinal Research Reviews, 44 (3), 1121-1146. doi: 10.1002/med.22010 |
|
2023 Journal Article MA09.03 High-dimensional profiling of the tumour microenvironment of non-small cell lung cancerKulasinghe, A., Monkman, J., Moradi, A., Yunis, J., Ivison, G., Mayer, A. and O'Byrne, K. (2023). MA09.03 High-dimensional profiling of the tumour microenvironment of non-small cell lung cancer. Journal of Thoracic Oncology, 18 (11), S129-s129. doi: 10.1016/j.jtho.2023.09.173 |
|
2023 Journal Article Genomic communication via circulating extracellular vesicles and long-term health consequences of COVID-19Nair, Soumyalekshmi, Nova-Lamperti, Estefania, Labarca, Gonzalo, Kulasinghe, Arutha, Short, Kirsty R., Carrión, Flavio and Salomon, Carlos (2023). Genomic communication via circulating extracellular vesicles and long-term health consequences of COVID-19. Journal of Translational Medicine, 21 (1) 709, 1-19. doi: 10.1186/s12967-023-04552-2 |
|
2023 Journal Article Mapping the spatial proteome of head and neck tumors: key immune mediators and metabolic determinants in the tumor microenvironmentJhaveri, Niyati, Ben Cheikh, Bassem, Nikulina, Nadezhda, Ma, Ning, Klymyshyn, Dmytro, DeRosa, James, Mihani, Ritu, Pratapa, Aditya, Kassim, Yasmin, Bommakanti, Sidharth, Shang, Olive, Berry, Shannon, Ihley, Nicholas, McLane, Michael, He, Yan, Zheng, Yi, Monkman, James, Cooper, Caroline, O'Byrne, Ken, Anand, Bhaskar, Prater, Michael, Basu, Subham, Hughes, Brett G. M., Kulasinghe, Arutha and Braubach, Oliver (2023). Mapping the spatial proteome of head and neck tumors: key immune mediators and metabolic determinants in the tumor microenvironment. GEN Biotechnology, 2 (5), 418-434. doi: 10.1089/genbio.2023.0029 |
|
2023 Journal Article The seductive allure of spatial biology: accelerating new discoveries in the life sciencesKulasinghe, Arutha, Wood, Fiona and Belz, Gabrielle (2023). The seductive allure of spatial biology: accelerating new discoveries in the life sciences. Immunology and Cell Biology, 101 (9), 798-804. doi: 10.1111/imcb.12669 |
|
2023 Journal Article Advances in novel strategies for isolation, characterization, and analysis of CTCs and ctDNAYaghoubi Naei, Vahid, Bordhan, Pritam, Mirakhorli, Fatemeh, Khorrami, Motahare, Shrestha, Jesus, Nazari, Hojjatollah, Kulasinghe, Arutha and Ebrahimi Warkiani, Majid (2023). Advances in novel strategies for isolation, characterization, and analysis of CTCs and ctDNA. Therapeutic Advances in Medical Oncology, 15 17588359231192401, 1-40. doi: 10.1177/17588359231192401 |
|
2023 Journal Article A robust platform for integrative spatial multi‐omics analysis to map immune responses to SARS‐CoV‐2 infection in lung tissuesTan, Xiao, Grice, Laura F., Tran, Minh, Mulay, Onkar, Monkman, James, Blick, Tony, Vo, Tuan, Almeida, Ana Clara, da Silva Motta, Jarbas, Fernandes de Moura, Karen, Machado‐Souza, Cleber, Souza‐Fonseca‐Guimaraes, Paulo, Baena, Cristina Pellegrino, de Noronha, Lucia, Guimaraes, Fernanda Simoes Fortes, Luu, Hung N., Drennon, Tingsheng, Williams, Stephen, Stern, Jacob, Uytingco, Cedric, Pan, Liuliu, Nam, Andy, Cooper, Caroline, Short, Kirsty, Belz, Gabrielle T., Souza‐Fonseca‐Guimaraes, Fernando, Kulasinghe, Arutha and Nguyen, Quan (2023). A robust platform for integrative spatial multi‐omics analysis to map immune responses to SARS‐CoV‐2 infection in lung tissues. Immunology, 170 (3), 401-418. doi: 10.1111/imm.13679 |
|
2023 Journal Article Multi‐omic and spatial dissection of immunotherapy response groups in non‐small cell lung cancerMonkman, James, Kim, Honesty, Mayer, Aaron, Mehdi, Ahmed, Matigian, Nicholas, Cumberbatch, Marie, Bhagat, Milan, Ladwa, Rahul, Mueller, Scott N., Adams, Mark N., O'Byrne, Ken and Kulasinghe, Arutha (2023). Multi‐omic and spatial dissection of immunotherapy response groups in non‐small cell lung cancer. Immunology, 169 (4), 487-502. doi: 10.1111/imm.13646 |
|
2023 Journal Article Mapping immunotherapy sensitivity with multiomic approachesKulasinghe, Arutha (2023). Mapping immunotherapy sensitivity with multiomic approaches. Immuno Oncology Insights, 4 (6), 235-237. doi: 10.18609/ioi.2023.031 |
|
2023 Journal Article Liquid biopsy snapshots of key phosphoproteomic pathways in lung cancer patients for diagnosis and therapy monitoringAhmed, Mostak, Wuethrich, Alain, Constantin, Nicolas, Shanmugasundaram, Karthik Balaji, Mainwaring, Paul, Kulasinghe, Arutha, O’Leary, Connor, O’Byrne, Ken, Sina, Abu Ali Ibn, Carrascosa, Laura G. and Trau, Matt (2023). Liquid biopsy snapshots of key phosphoproteomic pathways in lung cancer patients for diagnosis and therapy monitoring. Analytical Chemistry, 95 (22), 8522-8532. doi: 10.1021/acs.analchem.3c00519 |
|
2023 Journal Article Compartmentalized spatial profiling of the tumor microenvironment in head and neck squamous cell carcinoma identifies immune checkpoint molecules and tumor necrosis factor receptor superfamily members as biomarkers of response to immunotherapySadeghirad, Habib, Liu, Ning, Monkman, James, Ma, Ning, Cheikh, Bassem Ben, Jhaveri, Niyati, Tan, Chin Wee, Warkiani, Majid Ebrahimi, Adams, Mark N., Nguyen, Quan, Ladwa, Rahul, Braubach, Oliver, O’Byrne, Ken, Davis, Melissa, Hughes, Brett G. M. and Kulasinghe, Arutha (2023). Compartmentalized spatial profiling of the tumor microenvironment in head and neck squamous cell carcinoma identifies immune checkpoint molecules and tumor necrosis factor receptor superfamily members as biomarkers of response to immunotherapy. Frontiers in Immunology, 14 1135489, 1-16. doi: 10.3389/fimmu.2023.1135489 |
|
2023 Journal Article Blood transcriptome responses in patients correlate with severity of COVID-19 diseaseWang, Ya, Schughart, Klaus, Pelaia, Tiana Maria, Chew, Tracy, Kim, Karan, Karvunidis, Thomas, Knippenberg, Ben, Teoh, Sally, Phu, Amy L., Short, Kirsty R., Iredell, Jonathan, Thevarajan, Irani, Audsley, Jennifer, Macdonald, Stephen, Burcham, Jonathon, McLean, Anthony, Tang, Benjamin, Shojaei, Maryam, PREDICT-19 consortium, Kulasinghe, Arutha and Carney, Meagan E. (2023). Blood transcriptome responses in patients correlate with severity of COVID-19 disease. Frontiers in Immunology, 13 1043219, 1-18. doi: 10.3389/fimmu.2022.1043219 |
|
2023 Journal Article IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational studyShojaei, Maryam, Shamshirian, Amir, Monkman, James, Grice, Laura, Tran, Minh, Tan, Chin Wee, Teo, Siok Min, Rodrigues Rossi, Gustavo, McCulloch, Timothy R., Nalos, Marek, Raei, Maedeh, Razavi, Alireza, Ghasemian, Roya, Gheibi, Mobina, Roozbeh, Fatemeh, Sly, Peter D., Spann, Kirsten M., Chew, Keng Yih, Zhu, Yanshan, Xia, Yao, Wells, Timothy J., Senegaglia, Alexandra Cristina, Kuniyoshi, Carmen Lúcia, Franck, Claudio Luciano, dos Santos, Anna Flavia Ribeiro, Noronha, Lucia de, Motamen, Sepideh, Valadan, Reza, Amjadi, Omolbanin ... Tang, Benjamin (2023). IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study. Frontiers in Immunology, 13 1060438, 1-14. doi: 10.3389/fimmu.2022.1060438 |
|
2022 Journal Article Transcriptomic profiling of cardiac tissues from SARS‐CoV ‐2 patients identifies DNA damageKulasinghe, Arutha, Liu, Ning, Tan, Chin Wee, Monkman, James, Sinclair, Jane E., Bhuva, Dharmesh D., Godbolt, David, Pan, Liuliu, Nam, Andy, Sadeghirad, Habib, Sato, Kei, Bassi, Gianluigi Li, O'Byrne, Ken, Hartmann, Camila, Miggiolaro, Anna Flavia Ribeiro dos Santos, Marques, Gustavo Lenci, Moura, Lidia Zytynski, Richard, Derek, Adams, Mark, Noronha, Lucia de, Baena, Cristina Pellegrino, Suen, Jacky Y., Arora, Rakesh, Belz, Gabrielle T., Short, Kirsty R., Davis, Melissa J., Souza‐Fonseca Guimaraes, Fernando and Fraser, John F. (2022). Transcriptomic profiling of cardiac tissues from SARS‐CoV ‐2 patients identifies DNA damage. Immunology, 168 (3), 403-419. doi: 10.1111/imm.13577 |
|
2022 Journal Article Single-cell analysis of circulating tumour cells: enabling technologies and clinical applicationsRadfar, Payar, Aboulkheyr Es, Hamidreza, Salomon, Rob, Kulasinghe, Arutha, Ramalingam, Naveen, Sarafraz-Yazdi, Ehsan, Thiery, Jean Paul and Warkiani, Majid Ebrahimi (2022). Single-cell analysis of circulating tumour cells: enabling technologies and clinical applications. Trends in Biotechnology, 40 (9), 1041-1060. doi: 10.1016/j.tibtech.2022.02.004 |
|
2022 Journal Article Immunotherapeutic targets in non‐small cell lung cancerSadeghi Rad, Habib, Bahrami, Tayyeb, Layeghi, Sepideh Mehrpour, Yousefi, Hassan, Rezaei, Meysam, Hosseini‐Fard, Seyed Reza, Radfar, Payar, Warkiani, Majid Ebrahimi, O’Byrne, Ken and Kulasinghe, Arutha (2022). Immunotherapeutic targets in non‐small cell lung cancer. Immunology, 168 (2), 1-17. doi: 10.1111/imm.13562 |
|
2022 Journal Article A robust experimental and computational analysis framework at multiple resolutions, modalities and coveragesTran, M., Yoon, S., Teoh, M., Andersen, S., Lam, PY., Purdue, B. W., Raghubar, A., Hanson, S.J., Devitt, K., Jones, K., Walters, S., Monkman, J., Kulasinghe, A., Tuong, Z.K., Soyer, H.P., Frazer, I. H. and Nguyen, Q. (2022). A robust experimental and computational analysis framework at multiple resolutions, modalities and coverages. Frontiers in Immunology, 13 911873, 911873. doi: 10.3389/fimmu.2022.911873 |
