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2022 Journal Article Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signaturesKulasinghe, Arutha, Tan, Chin Wee, dos Santos Miggiolaro, Anna Flavia Ribeiro, Monkman, James, SadeghiRad, Habib, Bhuva, Dharmesh D., da Silva Motta Junior, Jarbas, Vaz de Paula, Caroline Busatta, Nagashima, Seigo, Baena, Cristina Pellegrino, Souza-Fonseca-Guimaraes, Paulo, de Noronha, Lucia, McCulloch, Timothy, Rodrigues Rossi, Gustavo, Cooper, Caroline, Tang, Benjamin, Short, Kirsty R., Davis, Melissa J., Souza-Fonseca-Guimaraes, Fernando, Belz, Gabrielle T. and O'Byrne, Ken (2022). Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signatures. European Respiratory Journal, 59 (6) 2101881, 1-19. doi: 10.1183/13993003.01881-2021 |
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2025 Journal Article The development of a high-plex spatial proteomic methodology for the characterisation of the head and neck tumour microenvironmentTan, Chin Wee, Berrell, Naomi, Donovan, Meg L., Monkman, James, Lawler, Clara, Sadeghirad, Habib, Naei, Vahid Yaghoubi, Chen, Jinjin, Rossenbloom, Alyssa, Bonnett, Shilah, Conner, Mark, Filanoski, Brian, Kang, Christine, Beechem, Joseph M., Fraser, John F., Barnett, Catherine, Ladwa, Rahul, Hughes, Brett G. M. and Kulasinghe, Arutha (2025). The development of a high-plex spatial proteomic methodology for the characterisation of the head and neck tumour microenvironment. npj Precision Oncology, 9 (1) 191, 1. doi: 10.1038/s41698-025-00963-0 |
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2025 Other Outputs Metabolic microenvironment predictors of NSCLC immunotherapy responseKulasinghe, Arutha, Monkman, James, Tubelleza, Rafael, Kilgallon, Aaron and Lawler, Clara (2025). Metabolic microenvironment predictors of NSCLC immunotherapy response. The University of Queensland. (Dataset) doi: 10.48610/73b218c |
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2025 Conference Publication 2D and 3D spatial characterisation of tertiary lymphoid structures in head and neck cancer patients receiving immune checkpoint blockade therapyDonovan, Meg L., Sadeghirad, Habib, Berrell, Naomi, Monkman, James, Naei, Vahid Yaghoubi, Tan, Chin Wee, Yunis, Joseph, West, Zoe, Warkiani, Majid E., Ladwa, Rahul, Hughes, Brett G., Da Gama Duarte, Jessica and Kulasinghe, Arutha (2025). 2D and 3D spatial characterisation of tertiary lymphoid structures in head and neck cancer patients receiving immune checkpoint blockade therapy. AACR Annual Meeting 2025, Chicago, IL United States, 25-30 April 2025. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2025-5252 |
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2025 Conference Publication Characterising head and neck tumour microenvironment using high plex spatial omics technologies and analysesTan, Chin Wee, Berrell, Naomi, Donovan, Meg L., Monkman, James, Sadeghirad, Habib, Naei, Vahid Yaghoubi, Chen, Jinjin, Rossenbloom, Alyssa, Bonnett, Shilah, Conner, Mark, Filanoski, Brian, Kang, Christine, Beechem, Joseph M., Fraser, John F., Barnett, Catherine, Ladwa, Rahul, Hughes, Brett G. and Kulasinghe, Arutha (2025). Characterising head and neck tumour microenvironment using high plex spatial omics technologies and analyses. AACR Annual Meeting 2025, Chicago, IL United States, 25-30 April 2025. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2025-175 |
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2025 Conference Publication Spatial profiling of tumor microenvironment uncovers potential novel therapeutic approach in pediatric neuroblastomaTu, Cui, Tan, Chin Wee, Monkman, James, Almeida, Ana Clara, Antonio-Carreon, Gabrielle, Omer, Natacha, Hull, Giaan, Chung, Kimberly, Mehdi, Ahmed, Salerno, Antonietta, Vittorio, Orazio, Mayer, Aaron, Machado de Souza, Cleber, de Almeida Brehm Pinhati, Fernanda, Elifio-Esposito, Selene, Nicholls, Wayne, de Noronha, Lucia, Kulasinghe, Arutha and Souza-Fonseca-Guimaraes, Fernando (2025). Spatial profiling of tumor microenvironment uncovers potential novel therapeutic approach in pediatric neuroblastoma. AACR Annual Meeting 2025, Chicago, IL United States, 25-30 April 2025. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2025-2705 |
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2025 Conference Publication Tumor microenvironment profiling of multiplexed images in head and neck cancer reveals spatial features associated with immunotherapy responseMarkovits, Ettai, Monkman, James, Kilgallon, Aaron, Aung, Thazin Nwe, Rimm, David and Kulasinghe, Arutha (2025). Tumor microenvironment profiling of multiplexed images in head and neck cancer reveals spatial features associated with immunotherapy response. AACR Annual Meeting 2025, Chicago, IL United States, 25-30 April 2025. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2025-156 |
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2025 Conference Publication A Bayesian framework for unraveling disease biology from spatially resolved single-cell omics datasets by combining unbiased approaches with biological priors for cell-based microdomain discoveryFalkenstein, Brian, Yan, Raymond, Quinn, Shannon, Tosun, Akif Burak, Chennubhotla, S. Chakra, Kulasinghe, Arutha and Pullara, Filippo (2025). A Bayesian framework for unraveling disease biology from spatially resolved single-cell omics datasets by combining unbiased approaches with biological priors for cell-based microdomain discovery. AACR Annual Meeting 2025, Chicago, IL United States, 25-30 April 2025. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2025-2485 |
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2025 Conference Publication Unravelling melanoma brain metastasis tumor microenvironment characteristics using spatial transcriptomicsBelle, Clemence J., Brosda, Sandra, Bonazzi, Vanessa F., Bulteau, Victor, Stuart, Thomas, Xiong, Zherui, Lambie, Duncan, Johansson, Peter A., Aoude, Lauren G., Patel, Kalpana, Stehbens, Samantha J., Stark, Mitchell S., Haass, Nikolas K., Xu, Wen, Pinkham, Mark B., Foote, Matthew C., Olson, Sarah, Atkinson, Victoria, Kulasinghe, Arutha, Nguyen, Quan H. and Barbour, Andrew (2025). Unravelling melanoma brain metastasis tumor microenvironment characteristics using spatial transcriptomics. AACR Annual Meeting 2025, Chicago, IL United States, 25-30 April 2025. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2025-5076 |
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2025 Conference Publication Exploring PD1/PDL1 interactions and macrophage-tumor barriers in head and neck cancer: A spatial approach to immunotherapy responseNaei, Vahid Yaghoubi, Tubelleza, Rafael, Monkman, James, Sadeghirad, Habib, Donovan, Meg L., Blick, Tony, Wicher, Agata, Bodbin, Sara, Basu, Subham, Stad, Robert, Barnett, Catherine, O’Byrne, Ken, Ladwa, Rahul, Cooper, Caroline, Warkiani, Majid Ebrahimi, Hughes, Brett G.M. and Kulasinghe, Arutha (2025). Exploring PD1/PDL1 interactions and macrophage-tumor barriers in head and neck cancer: A spatial approach to immunotherapy response. AACR Annual Meeting 2025, Chicago, IL United States, 25-30 April 2025. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2025-750 |
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2025 Conference Publication Spatial deconvolution of non-small-cell lung cancer tissues prior to immune checkpoint inhibitor therapyMonkman, James, Tan, Chin Wee, Tubelleza, Rafael, OByrne, Ken and Kulasinghe, Arutha (2025). Spatial deconvolution of non-small-cell lung cancer tissues prior to immune checkpoint inhibitor therapy. AACR Annual Meeting 2025, Chicago, IL United States, 25-30 April 2025. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2025-2082 |
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2025 Journal Article Spatial interaction mapping of PD-1/PD-L1 in head and neck cancer reveals the role of macrophage-tumour barriers associated with immunotherapy responseNaei, Vahid Yaghoubi, Tubelleza, Rafael, Monkman, James, Sadeghirad, Habib, Donovan, Meg L., Blick, Tony, Wicher, Agata, Bodbin, Sara, Viratham, Amelie, Stad, Robert, Basu, Subham, Cooper, Caroline, Barnett, Catherine, O’Byrne, Ken, Ladwa, Rahul, Warkiani, Majid Ebrahimi, Hughes, Brett G. M. and Kulasinghe, Arutha (2025). Spatial interaction mapping of PD-1/PD-L1 in head and neck cancer reveals the role of macrophage-tumour barriers associated with immunotherapy response. Journal of Translational Medicine, 23 (1) 177, 177. doi: 10.1186/s12967-025-06186-y |
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2025 Book Chapter Spatial-Omics Methods and ApplicationsKulasinghe, Arutha, Berrell, Naomi, Donovan, Meg L. and Nilges, Benedikt S. (2025). Spatial-Omics Methods and Applications. Methods in Molecular Biology. (pp. 101-146) New York, NY: Springer US. doi: 10.1007/978-1-0716-4276-4_5 |
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2024 Journal Article Copper chelation redirects neutrophil function to enhance anti-GD2 antibody therapy in neuroblastomaRouaen, Jourdin R. C., Salerno, Antonietta, Shai-Hee, Tyler, Murray, Jayne E., Castrogiovanni, Giulia, McHenry, Charlotte, Jue, Toni Rose, Pham, Vu, Bell, Jessica Lilian, Poursani, Ensieh, Valli, Emanuele, Cazzoli, Riccardo, Damstra, Naomi, Nelson, Delia J., Stevens, Kofi L. P., Chee, Jonathan, Slapetova, Iveta, Kasherman, Maria, Whan, Renee, Lin, Francis, Cochran, Blake J., Tedla, Nicodemus, Veli, Feyza Colakoglu, Yuksel, Aysen, Mayoh, Chelsea, Saletta, Federica, Mercatelli, Daniele, Chtanova, Tatyana, Kulasinghe, Arutha ... Vittorio, Orazio (2024). Copper chelation redirects neutrophil function to enhance anti-GD2 antibody therapy in neuroblastoma. Nature Communications, 15 (1) 10462, 1-20. doi: 10.1038/s41467-024-54689-x |
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2024 Conference Publication Spatial dynamics and cellular architecture mapping in head and neck cancer: insights into immunotherapy responseKulasinghe, Arutha (2024). Spatial dynamics and cellular architecture mapping in head and neck cancer: insights into immunotherapy response. SITC 39th Annual Meeting (SITC 2024), Houston, TX United States, 6-10 November 2024. London, United Kingdom: BMJ Group. doi: 10.1136/jitc-2024-sitc2024.0110 |
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2024 Conference Publication Multi-omic spatial data integration resolves immunometabolic heterogeneity associated with Nivolumab response in non-small cell lung cancer (NSCLC) patientsYan, Raymond, Quinn, Shannon, Falkenstein, Brian, Monkman, James, O’Bryne, Kenneth, Chakra Chennubhotla, S, Pullara, Filippo and Kulasinghe, Arutha (2024). Multi-omic spatial data integration resolves immunometabolic heterogeneity associated with Nivolumab response in non-small cell lung cancer (NSCLC) patients. SITC 39th Annual Meeting (SITC 2024), Houston, TX United States, 6-10 November 2024. London, United Kingdom: BMJ Group. doi: 10.1136/jitc-2024-sitc2024.0212 |
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2024 Conference Publication An integrated approach to high dimensional spatial proteomics and interaction mapping in head and neck cancer tissues prior to immune checkpoint inhibitor therapyNaei, Vahid Yaghoubi, Monkman, James, Hughes, Brett and Kulasinghe, Arutha (2024). An integrated approach to high dimensional spatial proteomics and interaction mapping in head and neck cancer tissues prior to immune checkpoint inhibitor therapy. SITC 39th Annual Meeting (SITC 2024), Houston, TX United States, 6-10 November 2024. London, United Kingdom: BMJ Group. doi: 10.1136/jitc-2024-sitc2024.0558 |
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2024 Conference Publication Development of a novel immuno-metabolic spatial signature to predict response and resistance to immunotherapy in NSCLC patientsMarkovits, Ettai, Monkman, James, Aung, Thazin, Reeves, Jason, O’Byrne, Ken, Czertock, Rotem, Puig, Oscar, Rimm, David and Kulasinghe, Arutha (2024). Development of a novel immuno-metabolic spatial signature to predict response and resistance to immunotherapy in NSCLC patients. SITC 39th Annual Meeting (SITC 2024), Houston, TX United States, 6-10 November 2024. London, United Kingdom: BMJ Group. doi: 10.1136/jitc-2024-sitc2024.0109 |
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2024 Journal Article Spatial resolution of the head and neck cancer tumor microenvironment to identify tumor and stromal features associated with therapy responseBerrell, Naomi, Monkman, James, Donovan, Meg, Blick, Tony, O'Byrne, Ken, Ladwa, Rahul, Tan, Chin Wee and Kulasinghe, Arutha (2024). Spatial resolution of the head and neck cancer tumor microenvironment to identify tumor and stromal features associated with therapy response. Immunology and Cell Biology, 102 (9), 830-846. doi: 10.1111/imcb.12811 |
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2024 Conference Publication Deciphering Single-Cell Resolved Tumour Microenvironment Profiles Using Spatial Metabolic MappingKulasinghe, A., Monkman, J., Markovits, E. and O'Byrne, K. (2024). Deciphering Single-Cell Resolved Tumour Microenvironment Profiles Using Spatial Metabolic Mapping. 2024 World Conference on Lung Cancer, San Diego, CA United States, 7-10 September 2024. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.jtho.2024.09.032 |
