2013 Journal Article Lynch syndrome-associated breast cancers do not overexpress chromosome 11-encoded mucinsWalsh, Michael D., Cummings, Margaret C., Pearson, Sally-Ann, Clendenning, Mark, Walters, Rhiannon J., Nagler, Belinda, Hopper, John L., Jenkins, Mark A., Suthers, Graeme K., Goldblatt, Jack, Tucker, Kathy, Gattas, Michael R., Arnold, Julie L., Parry, Susan, Macrae, Finlay A., McGuckin, Michael A., Young, Joanne P. and Buchanan, Daniel D. (2013). Lynch syndrome-associated breast cancers do not overexpress chromosome 11-encoded mucins. Modern Pathology, 26 (7), 944-954. doi: 10.1038/modpathol.2012.232 |
2013 Journal Article Gastrointestinal cell lines form polarized epithelia with an adherent mucus layer when cultured in semi-wet interfaces with mechanical stimulationNavabi, Nazanin, McGuckin, Michael A. and Linden, Sara K. (2013). Gastrointestinal cell lines form polarized epithelia with an adherent mucus layer when cultured in semi-wet interfaces with mechanical stimulation. PLoS One, 8 (7) e68761, e68761.1-e68761.15. doi: 10.1371/journal.pone.0068761 |
2013 Journal Article Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteinsDas, Indrajit, Png, Chin Wen, Oancea, Iulia, Hasnain, Sumaira Z., Lourie, Rohan, Proctor, Martina, Eri, Rajaraman D., Sheng, Yong, Crane, Denis I., Florin, Timothy H. and McGuckin, Michael A. (2013). Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins. Journal of Experimental Medicine, 210 (6), 1201-1216. doi: 10.1084/jem.20121268 |
2013 Journal Article MUC1 and MUC13 differentially regulate epithelial inflammation in response to inflammatory and infectious stimuliSheng, Y. H., Triyana, S., Wang, R., Das, I., Gerloff, K., Florin, T. H., Sutton, P. and McGuckin, M. A. (2013). MUC1 and MUC13 differentially regulate epithelial inflammation in response to inflammatory and infectious stimuli. Mucosal Immunology, 6 (3), 557-568. doi: 10.1038/mi.2012.98 |
2013 Journal Article A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicityOancea, Iulia, Png, Chin Wen, Das, Indrajit, Lourie, Rohan, Winkler, Ingrid G., Eri, Rajaraman, Subramaniam, Nathan, Jinnah, H. A., McWhinney, Brett C., Levesque, Jean-Pierre, McGuckin, Michael A., Duley, John A. and Florin, Timothy H. J. (2013). A novel mouse model of veno-occlusive disease provides strategies to prevent thioguanine-induced hepatic toxicity. Gut, 62 (4), 594-605. doi: 10.1136/gutjnl-2012-302274 |
2013 Journal Article A novel NOD1- and CagA-independent pathway of interleukin-8 induction mediated by the Helicobacter pylori type IV secretion systemGorrell, Rebecca J., Guan, Jyeswei, Xin, Yue, Tafreshi, Mona Anoushiravani, Hutton, Melanie L., McGuckin, Michael A., Ferrero, Richard L. and Kwok, Terry (2013). A novel NOD1- and CagA-independent pathway of interleukin-8 induction mediated by the Helicobacter pylori type IV secretion system. Cellular Microbiology, 15 (4), 554-570. doi: 10.1111/cmi.12055 |
2013 Journal Article Extracellular cathepsin K exerts antimicrobial activity and is protective against chronic intestinal inflammation in miceSina, Christian, Lipinski, Simone, Gavrilova, Olga, Aden, Konrad, Rehman, Ateequr, Till, Andreas, Rittger, Andrea, Podschun, Rainer, Meyer-Hoffert, Ulf, Haesler, Robert, Midtling, Emilie, Puetsep, Katrin, McGuckin, Michael A., Schreiber, Stefan, Saftig, Paul and Rosenstiel, Philip (2013). Extracellular cathepsin K exerts antimicrobial activity and is protective against chronic intestinal inflammation in mice. Gut, 62 (4), 520-530. doi: 10.1136/gutjnl-2011-300076 |
2013 Journal Article Effect of long-term, low-dose erythromycin on pulmonary exacerbations among patients with non-cystic fibrosis bronchiectasis: the BLESS randomized controlled trialSerisier, David J., Martin, Megan L., McGuckin, Michael A., Lourie, Rohan, Chen, Alice C., Brain, Barbara, Biga, Sally, Schlebusch, Sanmarié, Dash, Peter and Bowler, Simon D. (2013). Effect of long-term, low-dose erythromycin on pulmonary exacerbations among patients with non-cystic fibrosis bronchiectasis: the BLESS randomized controlled trial. JAMA: The Journal of the American Medical Association, 309 (12), 1260-1267. doi: 10.1001/jama.2013.2290 |
2013 Journal Article Carbohydrate binding and gene expression by in vitro and in vivo propagated Campylobacter jejuni after Immunomagnetic SeparationKing, Rebecca M., Day, Christopher J., Hartley-Tassell, Lauren E., Connerton, Ian F., Tiralongo, Joe, McGuckin, Michael A. and Korolik, Victoria (2013). Carbohydrate binding and gene expression by in vitro and in vivo propagated Campylobacter jejuni after Immunomagnetic Separation. Journal of Basic Microbiology, 53 (3), 240-250. doi: 10.1002/jobm.201100466 |
2013 Journal Article Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironmentDong, Ying, Stephens, Carson, Walpole, Carina, Swedberg, Joakim E., Boyle, Glen M., Parsons, Peter G., McGuckin, Michael A., Harris, Jonathan M. and Clements, Judith A. (2013). Paclitaxel resistance and multicellular spheroid formation are induced by kallikrein-related peptidase 4 in serous ovarian cancer cells in an ascites mimicking microenvironment. PLoS One, 8 (2) e57056, e57056.1-e57056.12. doi: 10.1371/journal.pone.0057056 |
2013 Journal Article There is a 'uc' in mucus, but is there mucus in UC?McGuckin, Michael A. and Hasnain, Sumaira Z. (2013). There is a 'uc' in mucus, but is there mucus in UC?. Gut, 63 (2), 216-217. doi: 10.1136/gutjnl-2013-304602 |
2013 Journal Article IL-10 promotes production of intestinal mucus by suppressing protein misfolding and endoplasmic reticulum stress in goblet cellsHasnain, Sumaira Z., Tauro, Sharyn, Das, Indrajit, Tong, Hui, Chen, Alice C. -H., Jeffery, Penny L., McDonald, Victoria, Florin, Timothy H. and McGuckin, Michael A. (2013). IL-10 promotes production of intestinal mucus by suppressing protein misfolding and endoplasmic reticulum stress in goblet cells. Gastroenterology, 144 (2), 357-368. doi: 10.1053/j.gastro.2012.10.043 |
2013 Journal Article Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotypeWalsh, Michael D., Clendenning, Mark, Williamson, Elizabeth, Pearson, Sally-Ann, Walters, Rhiannon J., Nagler, Belinda, Packenas, David, Win, Aung K., Hopper, John L., Jenkins, Mark A., Haydon, Andrew M., Rosty, Christophe, English, Dallas R., Giles, Graham G., McGuckin, Michael A., Young, Joanne P. and Buchanan, Daniel D. (2013). Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype. Modern Pathology, 26 (12), 1642-1656. doi: 10.1038/modpathol.2013.101 |
2012 Journal Article Serine protease(s) secreted by the nematode Trichuris muris degrade the mucus barrierHasnain, Sumaira Z., McGuckin, Michael A., Grencis, Richard K. and Thornton, David J. (2012). Serine protease(s) secreted by the nematode Trichuris muris degrade the mucus barrier. PLoS Neglected Tropical Diseases, 6 (10) e1856, e1856.1-e1856.13. doi: 10.1371/journal.pntd.0001856 |
2012 Journal Article β-glucan triggers spondylarthritis and Crohn's disease–like ileitis in SKG miceRuutu, Merja, Thomas, Gethin, Steck, Roland, Degli-Esposti, Mariapia A., Zinkernagel, Martin S., Alexander, Kylie, Velasco, Jared, Strutton, Geoffrey, Tran, Ai, Benham, Helen, Rehaume, Linda, Wilson, Robert J., Kikly, Kristine, Davies, Julian, Pettit, Allison R., Brown, Matthew A., McGuckin, Michael A. and Thomas, Ranjeny (2012). β-glucan triggers spondylarthritis and Crohn's disease–like ileitis in SKG mice. Arthritis and Rheumatism, 64 (7), 2211-2222. doi: 10.1002/art.34423 |
2012 Journal Article O-Linked glycome and proteome of high-molecular-mass proteins in human ovarian cancer ascites: Identification of sulfation, disialic acid and O-linked fucoseKarlsson, Niclas G. and McGuckin, Michael A. (2012). O-Linked glycome and proteome of high-molecular-mass proteins in human ovarian cancer ascites: Identification of sulfation, disialic acid and O-linked fucose. Glycobiology, 22 (7), 918-929. doi: 10.1093/glycob/cws060 |
2012 Journal Article The interplay between endoplasmic reticulum stress and inflammationHasnain, Sumaira Z ., Lourie, Rohan, Das, Indrajit, Chen, Alice C-H. and McGuckin, Michael A. (2012). The interplay between endoplasmic reticulum stress and inflammation. Immunology and Cell Biology, 90 (3), 260-270. doi: 10.1038/icb.2011.112 |
2012 Journal Article Preface: introduction to mucin biology and technical challenges of mucin researchMcGuckin, Michael A. and Thornton, David J. (2012). Preface: introduction to mucin biology and technical challenges of mucin research. Mucins: Methods and Protocols, 842. |
2012 Journal Article Mucins in inflammatory bowel diseases and colorectal cancerSheng, Yong H., Hasnain, Sumaira Z., Florin, Timothy H. J. and McGuckin, Michael A. (2012). Mucins in inflammatory bowel diseases and colorectal cancer. Journal of Gastroenterology and Hepatology, 27 (1), 28-38. doi: 10.1111/j.1440-1746.2011.06909.x |
2011 Journal Article The MUC13 cell-surface mucin protects against intestinal inflammation by inhibiting epithelial cell apoptosisSheng, Yong H., Lourie, Rohan, Linden, Sara K., Jeffery, Penny L., Roche, Deborah, Tran, Thu V., Png, Chin W., Waterhouse, Nigel, Sutton, Philip, Florin, Timothy H. J. and McGuckin, Michael A. (2011). The MUC13 cell-surface mucin protects against intestinal inflammation by inhibiting epithelial cell apoptosis. Gut, 60 (12), 1661-1670. doi: 10.1136/gut.2011.239194 |