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2017 Journal Article Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsionHasnain, Sumaira Z., Dawson, Paul A., Lourie, Rohan, Hutson, Peter, Tong, Hui, Grencis, Richard K., McGuckin, Michael A. and Thornton, David J. (2017). Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion. PLoS Pathogens, 13 (2) e1006218, e1006218. doi: 10.1371/journal.ppat.1006218 |
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2017 Journal Article Enhanced colloidal stability, solubility and rapid dissolution of resveratrol by nanocomplexation with soy protein isolatePujara, Naisarg, Jambhrunkar, Siddharth, Wong, Kuan Yau, McGuckin, Michael and Popat, Amirali (2017). Enhanced colloidal stability, solubility and rapid dissolution of resveratrol by nanocomplexation with soy protein isolate. Journal of Colloid and Interface Science, 488, 303-308. doi: 10.1016/j.jcis.2016.11.015 |
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2017 Journal Article Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiomeVarelias, Antiopi, Ormerod, Kate L., Bunting, Mark D., Koyama, Motoko, Gartlan, Kate H., Kuns, Rachel D., Lachner, Nancy, Locke, Kelly R., Lim, Chun Y., Henden, Andrea S., Zhang, Ping, Clouston, Andrew D., Hasnain, Sumaira Z., McGuckin, Michael A., Blazar, Bruce R., MacDonald, Kelli P. A ., Hugenholtz, Philip and Hill, Geoffrey R. (2017). Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome. Blood, 129 (15), 2172-2185. doi: 10.1182/blood-2016-08-732628 |
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2016 Journal Article Macrolide treatment inhibits Pseudomonas aeruginosa quorum sensing in non-cystic fibrosis bronchiectasis. An analysis from the bronchiectasis and low-dose erythromycin study trialBurr, Lucy D., Rogers, Geraint B., Chen, Alice C.-H., Hamilton, Brett R., Pool, Gertruida F., Taylor, Steven L., Venter, Deon, Bowler, Simon D., Biga, Sally and McGuckin, Michael A. (2016). Macrolide treatment inhibits Pseudomonas aeruginosa quorum sensing in non-cystic fibrosis bronchiectasis. An analysis from the bronchiectasis and low-dose erythromycin study trial. Annals of the American Thoracic Society, 13 (10), 1697-1703. doi: 10.1513/AnnalsATS.201601-044OC |
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2016 Journal Article Colloidal mesoporous silica nanoparticles enhance the biological activity of resveratrolSummerlin, Natalie, Qu, Zhi, Pujara, Naisarg, Sheng, Yong, Jambhrunkar, Siddharth, McGuckin, Michael and Popat, Amirali (2016). Colloidal mesoporous silica nanoparticles enhance the biological activity of resveratrol. Colloids and Surfaces B: Biointerfaces, 144 (4), 1-7. doi: 10.1016/j.colsurfb.2016.03.076 |
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2016 Journal Article MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic targetSheng, Y. H., He, Y., Hasnain, S. Z., Wang, R., Tong, H., Clarke, D. T., Lourie, R., Oancea, I., Wong, K. Y., Lumley, J. W., Florin, T. H., Sutton, P., Hooper, J. D., McMillan, N. A. and McGuckin, M. A. (2016). MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target. Oncogene, 36 (5), 700-713. doi: 10.1038/onc.2016.241 |
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2016 Journal Article High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22Gulhane, Max, Murray, Lydia, Lourie, Rohan, Tong, Hui, Sheng, Yong H., Wang, Ran, Kang, Alicia, Schreiber, Veronika, Wong, Kuan Yau, Magor, Graham, Denman, Stuart, Begun, Jakob, Florin, Timothy H., Perkins, Andrew, Cuiv, Paraic O., McGuckin, Michael A. and Hasnain, Sumaira Z. (2016). High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22. Scientific Reports, 6 (1) 28990, 28990. doi: 10.1038/srep28990 |
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2016 Journal Article Oxidative and endoplasmic reticulum stress in beta-cell dysfunction in diabetesHasnain, Sumaira Z., Prins, Johannes B. and McGuckin, Michael A. (2016). Oxidative and endoplasmic reticulum stress in beta-cell dysfunction in diabetes. Journal of Molecular Endocrinology, 56 (2), R33-R54. doi: 10.1530/jme-15-0232 |
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2016 Journal Article Epithelial sel1L is required for the maintenance of intestinal homeostasisSun, Shengyi, Lourie, Rohan, Cohen, Sara B., Ji, Yewei, Goodrich, Julia K., Poole, Angela C., Ley, Ruth E., Denkers, Eric Y., McGuckin, Michael A., Long, Qiaoming, Duhamel, Gerald E., Simpson, Kenneth W. and Qi, Ling (2016). Epithelial sel1L is required for the maintenance of intestinal homeostasis. Molecular Biology of the Cell, 27 (3), 483-490. doi: 10.1091/mbc.E15-10-0724 |
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2016 Journal Article FUT2 genotype influences lung function, exacerbation frequency and airway microbiota in non-CF bronchiectasisTaylor, Steven L., Woodman, Richard J., Chen, Alice C. H., Burr, Lucy D., Gordon, David L., McGuckin, Michael A., Wesselingh, Steve and Rogers, Geraint B. (2016). FUT2 genotype influences lung function, exacerbation frequency and airway microbiota in non-CF bronchiectasis. Thorax, 72 (4), 304-310. doi: 10.1136/thoraxjnl-2016-208775 |
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2015 Journal Article Matrix metalloproteinases vary with airway microbiota composition and lung function in non-cystic fibrosis bronchiectasisTaylor, Steven L., Rogers, Geraint B., Chen, Alice C.-H., Burr, Lucy D., McGuckin, Michael A. and Serisier, David J. (2015). Matrix metalloproteinases vary with airway microbiota composition and lung function in non-cystic fibrosis bronchiectasis. Annals of the American Thoracic Society, 12 (5), 701-707. doi: 10.1513/AnnalsATS.201411-513OC |
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2015 Journal Article Neutralizing IL-23 is superior to blocking IL-17 in suppressing intestinal inflammation in a spontaneous murine colitis modelWang, Ran, Hasnain, Sumaira Z., Tong, Hui, Das, Indrajit, Che-Hao Chen, Alice, Oancea, Iulia, Proctor, Martina, Florin, Timothy H., Eri, Rajaraman D. and McGuckin, Michael A. (2015). Neutralizing IL-23 is superior to blocking IL-17 in suppressing intestinal inflammation in a spontaneous murine colitis model. Inflammatory Bowel Diseases, 21 (5), 973-984. doi: 10.1097/MIB.0000000000000353 |
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2015 Journal Article The MUC1 mucin protects against Helicobacter pylori pathogenesis in mice by regulation of the NLRP3 inflammasomeNg, Garrett Z., Menheniott, Trevelyan R., Every, Alison L., Stent, Andrew, Judd, Louise M., Chionh, Yok Teng, Dhar, Poshmaal, Komen, Jasper C., Giraud, Andrew S., Wang, Timothy C., McGuckin, Michael A. and Sutton, Philip (2015). The MUC1 mucin protects against Helicobacter pylori pathogenesis in mice by regulation of the NLRP3 inflammasome. Gut, 65 (7), 1-13. doi: 10.1136/gutjnl-2014-307175 |
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2015 Journal Article Adult non-cystic fibrosis bronchiectasis is characterised by airway luminal Th17 pathway activationChen, Alice C.-H., Martin, Megan L., Lourie, Rohan, Rogers, Geraint B., Burr, Lucy D., Hasnain, Sumaira Z., Bowler, Simon D., McGuckin, Michael A. and Serisier, David J. (2015). Adult non-cystic fibrosis bronchiectasis is characterised by airway luminal Th17 pathway activation. PLoS ONE, 10 (3) e0119325, e0119325. doi: 10.1371/journal.pone.0119325 |
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2014 Journal Article Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stressHasnain, Sumaira Z., Borg, Danielle J., Harcourt, Brooke E., Tong, Hui, Sheng, Yonghua H., Ng, Choa Ping, Das, Indrajit, Wang, Ran, Chen, Alice C.-H., Loudovaris, Thomas, Kay, Thomas W., Thomas, Helen E., Whitehead, Jonathan P., Forbes, Josephine M., Prins, Johannes B. and McGuckin, Michael A. (2014). Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress. Nature Medicine, 20 (12), 1417-1426. doi: 10.1038/nm.3705 |
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2014 Journal Article ZAP-70 genotype disrupts the relationship between microbiota and host leading to spondyloarthritis and ileitis in SKG MiceRehaume, Linda, Mondot, Stanislas, Aguirre de Cárcer, Daniel, Velasco, Jared, Benham, Helen, Hasnain, Sumaira Zia, Bowman, Jaclyn, Ruutu, Merja, Hansbro, Philip M., McGuckin, Michael, Morrison, Mark and Thomas, Ranjeny (2014). ZAP-70 genotype disrupts the relationship between microbiota and host leading to spondyloarthritis and ileitis in SKG Mice. Arthritis and Rheumatology, 66 (10), 2780-2792. doi: 10.1002/art.38773 |
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2014 Journal Article Interleukin-23 mediates the intestinal response to microbial beta-glucan and the development of spondyloarthritis pathology in SKG miceBenham, Helen, Rehaume, Linda M., Hasnain, Sumaira Z., Velasco, Jared, Baillet, Athan C., Ruutu, Merja, Kikly, Kristine, Wang, Ran, Tseng, Hsu-Wen, Thomas, Gethin P., Brown, Matthew A., Strutton, Geoffrey, McGuckin, Michael A. and Thomas, Ranjeny (2014). Interleukin-23 mediates the intestinal response to microbial beta-glucan and the development of spondyloarthritis pathology in SKG mice. Arthritis and Rheumatology, 66 (7), 1755-1767. doi: 10.1002/art.38638 |
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2014 Journal Article Functional divergence in gastrointestinal microbiota in physically-separated genetically identical miceRogers, G. B., Kozlowska, J., Keeble, J., Metcalfe, K., Fao, M., Dowd, S. E., Mason, A. J., McGuckin, M. A. and Bruce, K. D. (2014). Functional divergence in gastrointestinal microbiota in physically-separated genetically identical mice. Scientific Reports, 4 (1) 5437. doi: 10.1038/srep05437 |
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2014 Journal Article A novel microbiota stratification system predicts future exacerbations in bronchiectasisRogers, Geraint B., Zain, Nur Masirah M., Bruce, Kenneth D., Burr, Lucy D., Chen, Alice C., Rivett, Damian W., McGuckin, Michael A. and Serisier, David J. (2014). A novel microbiota stratification system predicts future exacerbations in bronchiectasis. Annals of the American Thoracic Society, 11 (4), 496-503. doi: 10.1513/AnnalsATS.201310-335OC |
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2014 Journal Article Selenoprotein S is a marker but not a regulator of endoplasmic reticulum stress in intestinal epithelial cellsSpeckmann, Bodo, Gerloff, Kirsten, Simms, Lisa, Oancea, Iulia, Shi, Wei, McGuckin, Michael A., Radford-Smith, Graham and Khanna, Kum Kum (2014). Selenoprotein S is a marker but not a regulator of endoplasmic reticulum stress in intestinal epithelial cells. Free Radical Biology and Medicine, 67, 265-277. doi: 10.1016/j.freeradbiomed.2013.11.001 |
