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2019

Journal Article

MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity

Sheng, Yong Hua, Wong, Kuan Yau, Seim, Inge, Wang, Ran, He, Yaowu, Wu, Andy, Patrick, Maya, Lourie, Rohan, Schreiber, Veronika, Giri, Rabina, Ng, Choa Ping, Popat, Amirali, Hooper, John, Kijanka, Gregor, Florin, Timothy H., Begun, Jakob, Radford, Kristen J., Hasnain, Sumaira and McGuckin, Michael A. (2019). MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity. Oncogene, 38 (48), 7294-7310. doi: 10.1038/s41388-019-0951-y

MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity

2019

Journal Article

Interleukin (IL)-22 from IL-20 Subfamily of cytokines induces colonic epithelial cell proliferation predominantly through ERK1/2 pathway

Moniruzzaman, Md., Wang, Ran, Jeet, Varinder, McGuckin, Michael A. and Hasnain, Sumaira Z. (2019). Interleukin (IL)-22 from IL-20 Subfamily of cytokines induces colonic epithelial cell proliferation predominantly through ERK1/2 pathway. International Journal of Molecular Sciences, 20 (14) 3468, 3468. doi: 10.3390/ijms20143468

Interleukin (IL)-22 from IL-20 Subfamily of cytokines induces colonic epithelial cell proliferation predominantly through ERK1/2 pathway

2019

Journal Article

Responsive polysaccharide-grafted surfaces for biotribological applications

Pradal, Clementine, Yakubov, Gleb E., Williams, Martin A.K., McGuckin, Michael A. and Stokes, Jason R. (2019). Responsive polysaccharide-grafted surfaces for biotribological applications. Biotribology, 18 100092, 100092. doi: 10.1016/j.biotri.2019.100092

Responsive polysaccharide-grafted surfaces for biotribological applications

2019

Journal Article

Fibre intake is independently associated with increased circulating interleukin-22 in individuals with metabolic syndrome

Torquati, Luciana, Coombes, Jeff S., Murray, Lydia, Hasnain, Sumaira Z., Mallard, Alistair R., McGuckin, Michael A., Fassett, Robert G., Croci, Ilaria and Ramos, Joyce S. (2019). Fibre intake is independently associated with increased circulating interleukin-22 in individuals with metabolic syndrome. Nutrients, 11 (4) 815, 815. doi: 10.3390/nu11040815

Fibre intake is independently associated with increased circulating interleukin-22 in individuals with metabolic syndrome

2019

Journal Article

GRP78 expression in tumor and perinephric adipose tissue is not an optimal risk stratification marker for clear cell renal cell carcinoma

Shen, Kunyu, Vesey, David A., Ellis, Robert J., Del Vecchio, Sharon Juliet, Cho, Yeoungjee, Teixeira-Pinto, Armando, McGuckin, Michael A., Johnson, David W. and Gobe, Glenda C. (2019). GRP78 expression in tumor and perinephric adipose tissue is not an optimal risk stratification marker for clear cell renal cell carcinoma. PLoS One, 14 (1) e0210246, e0210246. doi: 10.1371/journal.pone.0210246

GRP78 expression in tumor and perinephric adipose tissue is not an optimal risk stratification marker for clear cell renal cell carcinoma

2018

Journal Article

A peculiar case of Campylobacter jejuni attenuated aspartate chemosensory mutant, able to cause pathology and inflammation in avian and murine model animals

Hartley-Tassell, L. E., Day, C. J., Semchenko, E. A., Tram, G., Calderon-Gomez, L. I., Klipic, Z., Barry, A. M., Lam, A. K., McGuckin, M. A. and Korolik, V. (2018). A peculiar case of Campylobacter jejuni attenuated aspartate chemosensory mutant, able to cause pathology and inflammation in avian and murine model animals. Scientific Reports, 8 (1) 12594. doi: 10.1038/s41598-018-30604-5

A peculiar case of Campylobacter jejuni attenuated aspartate chemosensory mutant, able to cause pathology and inflammation in avian and murine model animals

2018

Journal Article

PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa

Burr, Lucy D., Rogers, Geraint B., Chen, Alice C.-H., Taylor, Steven L., Bowler, Simon D., Keating, Rebecca L., Martin, Megan L., Hasnain, Sumaira Z. and McGuckin, Michael A. (2018). PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa. PLoS ONE, 13 (8) e0202296, e0202296. doi: 10.1371/journal.pone.0202296

PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa

2018

Journal Article

Enterococcus faecalis AHG0090 is a genetically tractable bacterium and produces a secreted peptidic bioactive that suppresses nuclear factor Kappa B activation in human gut epithelial cells

Ó Cuív, Páraic, Giri, Rabina, Hoedt, Emily C., McGuckin, Michael A., Begun, Jakob and Morrison, Mark (2018). Enterococcus faecalis AHG0090 is a genetically tractable bacterium and produces a secreted peptidic bioactive that suppresses nuclear factor Kappa B activation in human gut epithelial cells. Frontiers in Immunology, 9 (April) 790, 790. doi: 10.3389/fimmu.2018.00790

Enterococcus faecalis AHG0090 is a genetically tractable bacterium and produces a secreted peptidic bioactive that suppresses nuclear factor Kappa B activation in human gut epithelial cells

2018

Journal Article

Mucin gel assembly is controlled by a collective action of non-mucin proteins, disulfide bridges, Ca2+- mediated links, and hydrogen bonding

Medrum, Oliver W., Yakubov, Gleb E., Bonilla, Mauricio R., Deshmukh, Omkar, McGuckin, Michael A. and Gidley, Michael J. (2018). Mucin gel assembly is controlled by a collective action of non-mucin proteins, disulfide bridges, Ca2+- mediated links, and hydrogen bonding. Scientific Reports, 8 (1) 5802, 5802. doi: 10.1038/s41598-018-24223-3

Mucin gel assembly is controlled by a collective action of non-mucin proteins, disulfide bridges, Ca2+- mediated links, and hydrogen bonding

2018

Journal Article

Oxidative and endoplasmic reticulum stress in respiratory disease

Chen, Alice C-H, Burr, Lucy and McGuckin, Michael A. (2018). Oxidative and endoplasmic reticulum stress in respiratory disease. Clinical and Translational Immunology, 7 (6) e1019, e1019. doi: 10.1002/cti2.1019

Oxidative and endoplasmic reticulum stress in respiratory disease

2017

Journal Article

Evolution of the magic bullet: Single chain antibody fragments for the targeted delivery of immunomodulatory proteins

Fercher, Christian, Keshvari, Sahar, McGuckin, Michael A and Barnard, Ross T (2017). Evolution of the magic bullet: Single chain antibody fragments for the targeted delivery of immunomodulatory proteins. Experimental biology and medicine (Maywood, N.J.), 243 (2), 166-183. doi: 10.1177/1535370217748575

Evolution of the magic bullet: Single chain antibody fragments for the targeted delivery of immunomodulatory proteins

2017

Journal Article

Mucoadhesive functionality of cell wall structures from fruits and grains: Electrostatic and polymer network interactions mediated by soluble dietary polysaccharides

Meldrum, Oliver W, Yakubov, Gleb E, Gartaula, Ghanendra, McGuckin, Michael A and Gidley, Michael J (2017). Mucoadhesive functionality of cell wall structures from fruits and grains: Electrostatic and polymer network interactions mediated by soluble dietary polysaccharides. Scientific reports, 7 (1) 15794, 1-15. doi: 10.1038/s41598-017-16090-1

Mucoadhesive functionality of cell wall structures from fruits and grains: Electrostatic and polymer network interactions mediated by soluble dietary polysaccharides

2017

Journal Article

Infection's Sweet Tooth: How Glycans Mediate Infection and Disease Susceptibility

Taylor, Steven L., McGuckin, Michael A., Wesselingh, Steve and Rogers, Geraint B. (2017). Infection's Sweet Tooth: How Glycans Mediate Infection and Disease Susceptibility. Trends in Microbiology, 26 (2), 92-101. doi: 10.1016/j.tim.2017.09.011

Infection's Sweet Tooth: How Glycans Mediate Infection and Disease Susceptibility

2017

Journal Article

Role of the unfolded protein response in determining the fate of tumor cells and the promise of multi-targeted therapies

Shen, Kunyu, Johnson, David W., Vesey, David A., McGuckin, Michael A. and Gobe, Glenda C. (2017). Role of the unfolded protein response in determining the fate of tumor cells and the promise of multi-targeted therapies. Cell Stress and Chaperones, 23 (3), 317-334. doi: 10.1007/s12192-017-0844-3

Role of the unfolded protein response in determining the fate of tumor cells and the promise of multi-targeted therapies

2017

Journal Article

Goblet cells as mucosal sentinels for immunity

McGuckin, M. A. and Hasnain, S. Z. (2017). Goblet cells as mucosal sentinels for immunity. Mucosal Immunology, 10 (5), 1118-1121. doi: 10.1038/mi.2016.132

Goblet cells as mucosal sentinels for immunity

2017

Journal Article

The effect of interleukin-22 treatment on autoimmune diabetes in the NOD mouse

Borg, Danielle J., Wang, Ran, Murray, Lydia, Tong, Hui, Steptoe, Raymond J., McGuckin, Michael A. and Hasnain, Sumaira Z. (2017). The effect of interleukin-22 treatment on autoimmune diabetes in the NOD mouse. Diabetologia, 60 (11), 1-6. doi: 10.1007/s00125-017-4392-2

The effect of interleukin-22 treatment on autoimmune diabetes in the NOD mouse

2017

Journal Article

The cell surface mucin MUC1 limits the severity of influenza A virus infection

McAuley, J. L., Corcilius, L., Tan, H. -X., Payne, R. J., McGuckin, M. A. and Brown, L. E. (2017). The cell surface mucin MUC1 limits the severity of influenza A virus infection. Mucosal Immunology, 10 (6), 1581-1593. doi: 10.1038/mi.2017.16

The cell surface mucin MUC1 limits the severity of influenza A virus infection

2017

Journal Article

Bifunctional succinylated ε-polylysine-coated mesoporous silica nanoparticles for pH-responsive and intracellular drug delivery targeting the colon

Nguyen, Chau T. H., Webb, Richard I., Lambert, Lynette K., Strounina, Ekaterina, Lee, Edward C., Parat, Marie-Odile, McGuckin, Michael A., Popat, Amirali, Cabot, Peter J. and Ross, Benjamin P. (2017). Bifunctional succinylated ε-polylysine-coated mesoporous silica nanoparticles for pH-responsive and intracellular drug delivery targeting the colon. ACS Applied Materials and Interfaces, 9 (11), 9470-9483. doi: 10.1021/acsami.7b00411

Bifunctional succinylated ε-polylysine-coated mesoporous silica nanoparticles for pH-responsive and intracellular drug delivery targeting the colon

2017

Journal Article

Is there a link between H. Pylori and the epidemiology of Crohn’s disease?

Shah, Ayesha, Talley, Nicholas J., Walker, Marjorie, Koloski, Natasha, Morrison, Mark, Burger, Daniel, Andrews, Jane M., McGuckin, Michael, Jones, Mike and Holtmann, Gerald (2017). Is there a link between H. Pylori and the epidemiology of Crohn’s disease?. Digestive Diseases and Sciences, 62 (9), 1-9. doi: 10.1007/s10620-017-4496-z

Is there a link between H. Pylori and the epidemiology of Crohn’s disease?

2017

Journal Article

MUC13 overexpression in renal cell carcinoma plays a central role in tumor progression and drug resistance

Sheng, Yonghua, Ng, Choa Ping, Lourie, Rohan, Shah, Esha T., He, Yaowu, Wong, Kuan Yua, Seim, Inge, Oancea, Iulia, Morais, Christudas, Jeffery, Penny L., Hooper, John, Gobe, Glenda C. and Mcguckin, Michael A. (2017). MUC13 overexpression in renal cell carcinoma plays a central role in tumor progression and drug resistance. International Journal of Cancer, 140 (10), 2351-2363. doi: 10.1002/ijc.30651

MUC13 overexpression in renal cell carcinoma plays a central role in tumor progression and drug resistance