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2022

Conference Publication

A novel role for interleukin-22 signaling in modulating mucosal epithelial cell antigen presentation machinery to control disease

Rahman, M. A., Moniruzzaman, M., Wang, R., Harding, A., Wiid, P., Sajiir, H., Yong, K. Y., Sheng, Y., Mueller, A., Symon, H., Varelias, A., McGuckin, M., Phipps, S. and Hasnain, S. (2022). A novel role for interleukin-22 signaling in modulating mucosal epithelial cell antigen presentation machinery to control disease. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW), Sydney, NSW, Australia, 9–11 September 2022. Richmond, VIC, Australia: John Wiley & Sons.

A novel role for interleukin-22 signaling in modulating mucosal epithelial cell antigen presentation machinery to control disease

2022

Conference Publication

Building a case for pancreas and liver targeted intereukin-22 therapy in fatty liver disease

Sajiir, Haressh, Wong, Kuan Yau, Mueller, Alexandra, Keshvari, Sahar, Wang, Ran, Wiid, Percival, Ramm, Grant, Macdonald, Graeme, Prins, John, McGuckin, Michael and Hasnain, Sumaira (2022). Building a case for pancreas and liver targeted intereukin-22 therapy in fatty liver disease. The International Liver Congress 2022, London, United Kingdom, 22-26 June 2022. Amsterdam, Netherlands: Elsevier. doi: 10.1016/s0168-8278(22)00756-5

Building a case for pancreas and liver targeted intereukin-22 therapy in fatty liver disease

2022

Conference Publication

Targeted IL-22 Improves Glucose Tolerance and Reduces Hepatic Steatosis and Hepatic Fibrosis in Murine Models of Diabetes and Liver Disease

Prins, John B., Sajiir, Haressh, Keshvari, Sahar, Wong, Kuan Yau, Lockett, Jack, McGuckin, Michael and Hasnain, Sumaira Z. (2022). Targeted IL-22 Improves Glucose Tolerance and Reduces Hepatic Steatosis and Hepatic Fibrosis in Murine Models of Diabetes and Liver Disease. American Diabetes Association 82nd Scientific Sessions, New Orleans, LA United States, 3-7 June 2021. Arlington, VA United States: American Diabetes Association. doi: 10.2337/db22-119-lb

Targeted IL-22 Improves Glucose Tolerance and Reduces Hepatic Steatosis and Hepatic Fibrosis in Murine Models of Diabetes and Liver Disease

2022

Conference Publication

Building a case for liver and pancreas targeted interleukin-22 therapy for use in non-alcoholic fatty liver disease

Sajiir, Haressh, Wong, Kuanyau, Mueller, Alexander, Keshvari, Sahar, Wang, Ran, Macdonald, Graeme A., Prins, John, Mcguckin, Michael and Hasnain, Sumaira Z. (2022). Building a case for liver and pancreas targeted interleukin-22 therapy for use in non-alcoholic fatty liver disease. Digestive Disease Week 2022, San Diego, CA United States, 21-24 May 2022. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(22)60035-0

Building a case for liver and pancreas targeted interleukin-22 therapy for use in non-alcoholic fatty liver disease

2022

Conference Publication

Pancreatic Interleukin-22 Receptor Signaling is Critical in Maintaining Beta-Cell Insulin Production and is Hepatoprotective

Sajiir, Haressh, Wong, Kuan Yau, Mueller, Alexandra, Keshvari, Sahar, Wang, Ran, Wiid, Percival, Macdonald, Graeme, Prins, John, McGuckin, Michael A. and Hasnain, Sumaira Z. (2022). Pancreatic Interleukin-22 Receptor Signaling is Critical in Maintaining Beta-Cell Insulin Production and is Hepatoprotective. Immunology 2022 Meeting, Portland, OR United States, 6-10 May 2022. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.208.supp.46.08

Pancreatic Interleukin-22 Receptor Signaling is Critical in Maintaining Beta-Cell Insulin Production and is Hepatoprotective

2020

Conference Publication

Thioguanine inhibits colorectal tumorigenesis via β-catenin signalling in intestinal epithelial cells independently of immunosuppression or autophagy

Sheng, Yong H., Giri, Rabina, Davies, Julie, Schreiber, Veronika, Alabbas, Saleh Y., He, Yaowu, Wu, Andy, Hooper, John, Oancea, Iulia, Kijanka, Gregor, Hasnain, Sumaira Z., McGuckin, Michael, Florin, Timothy H. and Begun, Jakob (2020). Thioguanine inhibits colorectal tumorigenesis via β-catenin signalling in intestinal epithelial cells independently of immunosuppression or autophagy. DDW 2020, Online, 2-5 May 2020. Philadelphia, PA United States: Elsevier . doi: 10.1016/s0016-5085(20)30856-8

Thioguanine inhibits colorectal tumorigenesis via β-catenin signalling in intestinal epithelial cells independently of immunosuppression or autophagy

2020

Conference Publication

Harnessing the therapeutic potential of interleukin-22 in neonatal respiratory viral infection

Hasnain, S., Wang, R., Taylor, S., Wong, K. Y., Moniruzzaman, M., Upham, J., Spann, K., Mcguckin, M. A., Burr, L. and Phipps, S. (2020). Harnessing the therapeutic potential of interleukin-22 in neonatal respiratory viral infection. TSANZSRS 2020 The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science, Melbourne, VIC, Australia, 27–31 March 2020. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.13777

Harnessing the therapeutic potential of interleukin-22 in neonatal respiratory viral infection

2018

Conference Publication

Airways mucus pathogenesis in patients with non-cystic fibrosis bronchiectasis

Ramsey, Kathryn, Radicioni, Giorgia, Hill, David, Ehre, Camille, Button, Brian, Alexis, Neil E., Knowles, Michael, Donaldson, Scott, Kesimer, Mehmet, Mcguckin, Michael and Boucher, Richard (2018). Airways mucus pathogenesis in patients with non-cystic fibrosis bronchiectasis. 28th International Congress of the European-Respiratory-Society (ERS), Paris France, Sep 15-19, 2018. SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD. doi: 10.1183/13993003.congress-2018.PA5049

Airways mucus pathogenesis in patients with non-cystic fibrosis bronchiectasis

2018

Conference Publication

Enteric microbiota shape the inflammatory response in mice with a Muc2 misfolding mutation

Wang, R., Giri, R., Moniruzzaman, M., Tong, H., Wong, K. Y., Begun, J., McGuckin, M. A. and Hasnain, S. Z. (2018). Enteric microbiota shape the inflammatory response in mice with a Muc2 misfolding mutation. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “Gut Matters”, Brisbane, QLD, Australia, 8-10 September 2018. Richmond, VIC, Australia: John Wiley & Sons.

Enteric microbiota shape the inflammatory response in mice with a Muc2 misfolding mutation

2018

Conference Publication

Interleukin-22: A potential therapy to control intestinal inflammation

Moniruzzaman, M., Wang, R., Wong, K. Y., Tong, H., McGuckin, M. A. and Hasnain, S. Z. (2018). Interleukin-22: A potential therapy to control intestinal inflammation. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “Gut Matters”, Brisbane, QLD, Australia, 8-10 September 2018. Richmond, VIC, Australia: John Wiley & Sons.

Interleukin-22: A potential therapy to control intestinal inflammation

2018

Conference Publication

Ubiquitin Ligase MARCH8 attenuates Graft versus Host Disease via Regulation of Gut Epithelial Cell Surface MHC II Expression

Lineburg, Katie E., Le Texier, Laetitia, Melino, Michelle, Wang, Ran, Clouston, Andrew, Blazar, Bruce R., McGuckin, Michael A., Villadangos, Jose A., Mintern, Justine D. and MacDonald, Kelli P. A. (2018). Ubiquitin Ligase MARCH8 attenuates Graft versus Host Disease via Regulation of Gut Epithelial Cell Surface MHC II Expression. 27th International Congress of the Transplantation-Society (TTS), Madrid, Spain, 30 June-5 July 2018. Philadelphia, PA, United States: Lippincott Williams & Wilkins. doi: 10.1097/01.tp.0000543013.84163.3a

Ubiquitin Ligase MARCH8 attenuates Graft versus Host Disease via Regulation of Gut Epithelial Cell Surface MHC II Expression

2018

Conference Publication

Airways Mucus Proteome Reveals Unique and Common Pathways in Non-CF Bronchiectasis and Primary Ciliary Dyskinesia

Radicioni, G., Ramsey, K. A., McGuckin, M., Knowles, M. R., Boucher, R. C. and Kesimer, M. (2018). Airways Mucus Proteome Reveals Unique and Common Pathways in Non-CF Bronchiectasis and Primary Ciliary Dyskinesia. International Conference of the American-Thoracic-Society, San Diego Ca, May 18-23, 2018. NEW YORK: AMER THORACIC SOC.

Airways Mucus Proteome Reveals Unique and Common Pathways in Non-CF Bronchiectasis and Primary Ciliary Dyskinesia

2017

Conference Publication

Effect of Differential Exercise Intensities on Interleukin-22 in Metabolic Syndrome

Ramos, Joyce S., Dalleck, Lance C., Mielke, Gregore I., Keating, Shelley E., McGuckin, Michael, Murray, Lydia S., Hasnain, Sumaira, Fassett, Robert G. and Coombes, Jeff S. (2017). Effect of Differential Exercise Intensities on Interleukin-22 in Metabolic Syndrome. Annual Meeting of the American-College-of-Sports-Medicine (ACSM), Denver Co, May 30-Jun 03, 2017. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. doi: 10.1249/01.mss.0000519264.21081.61

Effect of Differential Exercise Intensities on Interleukin-22 in Metabolic Syndrome

2016

Conference Publication

Unravelling a novel mechanism by which cytokines induce ER stress to halt viral protein synthesis in mucosal epithelial cells

Hasnain, S. Z., Taylor, S., Wang, R., Chen, A., Oancea, I, Das, I, Tong, H., Florin, T., Serisier, D., Coulson, B., Mcauley, J., Lourie, R., Phipps, S. and Mcguckin, M. (2016). Unravelling a novel mechanism by which cytokines induce ER stress to halt viral protein synthesis in mucosal epithelial cells. International Congress of Immunology (ICI), Melbourne, Australia, Aug 21-26, 2016. Weinheim, Germany: Wiley - V C H Verlag GmbH & Co. KGaA. doi: 10.1002/eji.201670200

Unravelling a novel mechanism by which cytokines induce ER stress to halt viral protein synthesis in mucosal epithelial cells

2016

Conference Publication

Erythromycin Inhibits Expression Of P. AerugINOSa Quorum Sensing Genes In The Airways Of Non-Cf Bronchiectasis Subjects Recruited To The Bless Randomised Controlled Trial

Burr, L. D., Rogers, G. B., Chen, A. C., Taylor, S., Bowler, S., Serisier, D. and McGuckin, M. (2016). Erythromycin Inhibits Expression Of P. AerugINOSa Quorum Sensing Genes In The Airways Of Non-Cf Bronchiectasis Subjects Recruited To The Bless Randomised Controlled Trial. International Conference of the American-Thoracic-Society (ATS), San Francisco Ca, May 13-18, 2016. New York, NY, United States: American Thoracic Society.

Erythromycin Inhibits Expression Of P. AerugINOSa Quorum Sensing Genes In The Airways Of Non-Cf Bronchiectasis Subjects Recruited To The Bless Randomised Controlled Trial

2016

Conference Publication

MUC13 protects colorectal cancer cells from death by activating the NF-Kb pathway and is a potential therapeutic target

Sheng, Yong H., He, Yaowu, Hasnain, Sumaira Z., Wang, Ran, Tong, Hui, Clarke, Daniel T., Lourie, Rohan, Oancea, Lulia, Wong, Kuanyau, Lumley, John W., Florin, Timothy H., Sutton, Philip, Hooper, John. D., Mcmillan, Nigel A. and Mcguckin, Michael A. (2016). MUC13 protects colorectal cancer cells from death by activating the NF-Kb pathway and is a potential therapeutic target. AACR 107th Annual Meeting on Bioinformatics and Systems Biology, New Orleans, Los Angeles, 16-20 April 2016 . Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2016-3564

MUC13 protects colorectal cancer cells from death by activating the NF-Kb pathway and is a potential therapeutic target

2016

Conference Publication

High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22

Gulhane, M., Lourie, R., Tong, H., Kang, A., Schreiber, V., Magor, G., Denman, S., Begun, J., Florin, T., Perkins, A., O Cuiv, P., Mcguckin, M. and Hasnain, S. Z. (2016). High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22. ICI 2016 International Congress of Immunology, Melbourne, Australia, 21–26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200

High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22

2015

Conference Publication

IL-22-mediated suppression of islet inflammation

McGuckin, Mike, Hasnain, Sumaira Z., Borg, Danielle J., Loudovaris, Thomas, Kay, Thomas W., Thomas, Helen E., Whitehead, Jonathon P., Forbes, Josephine M. and Prins, John B. (2015). IL-22-mediated suppression of islet inflammation. IPITA/IXA/CTS Joint Congress, Melbourne Australia, Nov 15-19, 2015. HOBOKEN: LIPPINCOTT WILLIAMS & WILKINS.

IL-22-mediated suppression of islet inflammation

2015

Conference Publication

IL-22-MEDIATED SUPPRESSION OF ISLET INFLAMMATION

McGuckin, Mike, Hasnain, Sumaira Z., Borg, Danielle J., Loudovaris, Thomas, Kay, Thomas W., Thomas, Helen E., Whitehead, Jonathon P., Forbes, Josephine M. and Prins, John B. (2015). IL-22-MEDIATED SUPPRESSION OF ISLET INFLAMMATION. Joint Congress of the International-Pancreas-and-Islet-Transplantation-Association, International-Xenotransplantation-Association and Cell-Transplant-Society, Melbourne Australia, Nov 15-19, 2015. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

IL-22-MEDIATED SUPPRESSION OF ISLET INFLAMMATION

2015

Conference Publication

Collagen protease levels vary with airway microbiota composition and lung function in bronchiectasis

Taylor, S., Rogers, G., Chen, A., Burr, L., McGuckin, M. and Serisier, D. (2015). Collagen protease levels vary with airway microbiota composition and lung function in bronchiectasis. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Gold Coast, Australia, 27 March – 1 April 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.12495_14

Collagen protease levels vary with airway microbiota composition and lung function in bronchiectasis