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2019

Journal Article

Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia

Somers, Klaartje, Evans, Kathryn, Cheung, Leanna, Karsa, Mawar, Pritchard, Tara, Kosciolek, Angelika, Bongers, Angelika, El-Ayoubi, Ali, Forgham, Helen, Middlemiss, Shiloh, Mayoh, Chelsea, Jones, Luke, Gupta, Mahima, Kees, Ursula R., Chernova, Olga, Korotchkina, Lioubov, Gudkov, Andrei V., Erickson, Stephen W., Teicher, Beverly, Smith, Malcolm A., Norris, Murray D., Haber, Michelle, Lock, Richard B. and Henderson, Michelle J. (2019). Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia. Leukemia, 34 (6), 1524-1539. doi: 10.1038/s41375-019-0683-6

Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia

2019

Journal Article

Identification of novel medulloblastoma cell-targeting peptides for use in selective chemotherapy drug delivery

Tjandra, Kristel C., McCarthy, Nigel, Yang, Lu, Laos, Alistair J., Sharbeen, George, Phillips, Phoebe A., Forgham, Helen, Sagnella, Sharon M., Whan, Renee M., Kavallaris, Maria, Thordarson, Pall and McCarroll, Joshua A. (2019). Identification of novel medulloblastoma cell-targeting peptides for use in selective chemotherapy drug delivery. Journal of Medicinal Chemistry, 63 (5), 2181-2193. doi: 10.1021/acs.jmedchem.9b00851

Identification of novel medulloblastoma cell-targeting peptides for use in selective chemotherapy drug delivery

2019

Journal Article

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

Somers, Klaartje, Wen, Victoria W., Middlemiss, Shiloh M. C., Osborne, Brenna, Forgham, Helen, Jung, MoonSun, Karsa, Mawar, Clifton, Molly, Bongers, Angelika, Gao, Jixuan, Mayoh, Chelsea, Raoufi-Rad, Newsha, Kusnadi, Eric P., Hannan, Kate M., Scott, David A., Kwek, Alan, Liu, Bing, Flemming, Claudia, Chudakova, Daria A., Pandher, Ruby, Failes, Tim W., Lim, James, Angeli, Andrea, Osterman, Andrei L., Imamura, Toshihiko, Kees, Ursula R., Supuran, Claudiu T., Pearson, Richard B., Hannan, Ross D. ... Henderson, Michelle J. (2019). A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction. Oncogene, 38 (20), 3824-3842. doi: 10.1038/s41388-018-0666-5

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

2018

Journal Article

Differentiation of human embryonic stem cells to sympathetic neurons: a potential model for understanding neuroblastoma pathogenesis

Carr-Wilkinson, Jane, Prathalingam, Nilendran, Pal, Deepali, Moad, Mohammad, Lee, Natalie, Sundaresh, Aishwarya, Forgham, Helen, James, Peter, Herbert, Mary, Lako, Majlinda and Tweddle, Deborah A (2018). Differentiation of human embryonic stem cells to sympathetic neurons: a potential model for understanding neuroblastoma pathogenesis. Stem Cells International, 2018 4391641, 1-12. doi: 10.1155/2018/4391641

Differentiation of human embryonic stem cells to sympathetic neurons: a potential model for understanding neuroblastoma pathogenesis

2015

Journal Article

Stem cell markers in neuroblastoma—an emerging role for LGR5

Forgham, Helen, Johnson, Darren, Carter, Noel, Veuger, Stephany and Carr-Wilkinson, Jane (2015). Stem cell markers in neuroblastoma—an emerging role for LGR5. Frontiers in Cell and Developmental Biology, 3 (DEC) 77. doi: 10.3389/fcell.2015.00077

Stem cell markers in neuroblastoma—an emerging role for LGR5