|
2010 Journal Article The ZFHX3 (ATBF1) transcription factor induces PDGFRB, which activates ATM in the cytoplasm to protect cerebellar neurons from oxidative stressKim, TS, Kawaguchi, M, Suzuki, M, Jung, CG, Asai, K, Shibamoto, Y, Lavin, MF, Khanna, KK and Miura, Y (2010). The ZFHX3 (ATBF1) transcription factor induces PDGFRB, which activates ATM in the cytoplasm to protect cerebellar neurons from oxidative stress. DMM Disease Models and Mechanisms, 3 (11-12), 752-762. doi: 10.1242/dmm.004689 |
|
2010 Journal Article A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activationHinz, Michael, Stilmann, Michael, Arslan, Seda Çöl, Khanna, Kum Kum, Dittmar, Gunnar and Scheidereit, Claus (2010). A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation. Molecular Cell, 40 (1), 63-74. doi: 10.1016/j.molcel.2010.09.008 |
|
2010 Journal Article Subtypes of familial breast tumours revealed by expression and copy number profilingWaddell, N, Arnold, J, Cocciardi, S, da Silva, L, Marsh, A, Riley, J, Johnstone, CN, Orloff, M, Assie, G, Eng, C, Reid, L, Keith, P, Yan, M, Fox, S, Devilee, P, Godwin, AK, Hogervorst, FBL, Couch, F, Grimmond, S, Flanagan, JM, Khanna, K, Simpson, PT, Lakhani, SR, Chenevix-Trench, G and kConFab Investigators (2010). Subtypes of familial breast tumours revealed by expression and copy number profiling. Breast Cancer Research And Treatment, 123 (3), 661-677. doi: 10.1007/s10549-009-0653-1 |
|
2010 Journal Article Novel single stranded DNA binding proteins crucial for the DNA damage responseCubeddu, L., Richard, D. J., White, M. F. and Khanna, K. K. (2010). Novel single stranded DNA binding proteins crucial for the DNA damage response. The FEBS Journal, 277 (Supp. 1), 193-193. doi: 10.1111/j.1742-4658.2010.07680.x |
|
2010 Journal Article Centrobin regulates the assembly of functional mitotic spindlesJeffery, J. M., Urquhart, A. J., Subramaniam, V. N., Parton, R.G. and Khanna, K.K. (2010). Centrobin regulates the assembly of functional mitotic spindles. Oncogene, 29 (18), 2649-2658. doi: 10.1038/onc.2010.37 |
|
2010 Journal Article Selenium and selenoproteins in health and diseasePapp, Laura V., Holmgren, Arne and Khanna, Kum Kum (2010). Selenium and selenoproteins in health and disease. Antioxidants and Redox Signaling, 12 (7), 793-795. doi: 10.1089/ars.2009.2973 |
|
2010 Journal Article SECIS-binding protein 2 promotes cell survival by protecting against oxidative stressPapp, Laura V., Lu, Jun, Bolderson, Emma, Boucher, Didier, Singh, Ravindra, Holmgren, Arne and Khanna, Kum Kum (2010). SECIS-binding protein 2 promotes cell survival by protecting against oxidative stress. Antioxidants and Redox Signaling, 12 (7), 797-808. doi: 10.1089/ars.2009.2913 |
|
2010 Journal Article Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaksBolderson, Emma, Tomimatsu, Nozomi, Richard, Derek J., Boucher, Didier, Kumar, Rakesh, Pandita, Tej K., Burma, Sandeep and Khanna, Kum Kum (2010). Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks. Nucleic Acids Research, 38 (6) gkp1164, 1821-1831. doi: 10.1093/nar/gkp1164 |
|
2010 Journal Article DNA methylome of familial breast cancer identifies distinct profiles defined by mutation statusFlanagan, James M., Cocciardi, Sibylle, Waddell, Nic, Johnstone, Cameron N., Marsh, Anna, Henderson, Stephen, Simpson, Peter, da Silva, Leonard, kConFab Investigators, Khanna, Kumkum, Lakhani, Sunil, Boshoff, Chris, Chenevix-Trench, Georgia, Brown, Melissa, Cummings, Margaret and Edwards, Stacey (2010). DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status. American Journal of Human Genetics, 86 (3), 420-433. doi: 10.1016/j.ajhg.2010.02.008 |
|
2010 Journal Article Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?Lakhani, Sunil R., Khanna, Kum K. and Chenevix-Trench, Georgia (2010). Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?. Breast Cancer Research, 12 (2) 104, 104-1-104-2. doi: 10.1186/bcr2483 |
|
2010 Journal Article HER3 and downstream pathways are involved in colonization of brain metastases from breast cancerDa Silva, Leonard, Simpson, Peter T., Smart, Chanek E., Cocciardi, Sibylle, Waddell, Nic, Lane, Annette, Morrison, Brian J., Vargas, Ana Cristina, Healey, Sue, Beesley, Jonathan, Pakkiri, Pria, Parry, Suzanne, Kurniawan, Nyoman, Reid, Lynne, Keith, Patricia, Faria, Paulo, Pereira, Emilio, Skalova, Alena, Bilous, Michael, Balleine, Rosemary L., Do, Hongdo, Dobrovic, Alexander, Fox, Stephen, Franco, Marcello, Reynolds, Brent, Khanna, Kum Kum, Cummings, Margaret, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2010). HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer. Breast Cancer Research, 12 (4) R46, R46-1-R46-11. doi: 10.1186/bcr2603 |
|
2009 Journal Article Cep55 stabilization is required for normal execution of cytokinesisArmando van der Horst, Jacinta Simmons and Kum Kum Khanna (2009). Cep55 stabilization is required for normal execution of cytokinesis. Cell Cycle, 8 (22), 3742-3749. doi: 10.4161/cc.8.22.10047 |
|
2009 Journal Article Recent Advances in Cancer Therapy Targeting Proteins Involved in DNA Double-Strand Break RepairEmma Bolderson, Derek J. Richard, Bin-Bing S. Zhou and Kum Kum Khanna (2009). Recent Advances in Cancer Therapy Targeting Proteins Involved in DNA Double-Strand Break Repair. Clinical Cancer Research, 15 (20), 6314-6320. doi: 10.1158/1078-0432.CCR-09-0096 |
|
2009 Journal Article Clinical and Molecular Characterization of a Novel Selenocysteine Insertion Sequence-Binding Protein 2 (SBP2) Gene Mutation (R128X)Caterina Di Cosmo, Neil McLellan, Xiao-Hui Liao, Kum Kum Khanna, Roy E. Weiss, Laura Papp and Samuel Refetoff (2009). Clinical and Molecular Characterization of a Novel Selenocysteine Insertion Sequence-Binding Protein 2 (SBP2) Gene Mutation (R128X). Journal of Clinical Endocrinology and Metabolism, 94 (10), 4003-4009. doi: 10.1210/jc.2009-0686 |
|
2009 Journal Article INTS3 controls the hSSB1-mediated DNA damage responseJeffrey R. Skaar, Derek J. Richard, Anita Saraf, Alfredo Toschi, Emma Bolderson, Laurence Florens, Michael P. Washburn, Kum Kum Khanna and Michele Pagano (2009). INTS3 controls the hSSB1-mediated DNA damage response. The Journal of Cell Biology, 187 (1), 25-32. doi: 10.1083/jcb.200907026 |
|
2009 Journal Article The Peptidyl-Prolyl Isomerase Pin1 Regulates Cytokinesis through Cep55Armando van der Horst and Kum Kum Khanna (2009). The Peptidyl-Prolyl Isomerase Pin1 Regulates Cytokinesis through Cep55. Cancer Research, 69 (16), 6651-6659. doi: 10.1158/0008-5472.CAN-09-0825 |
|
2009 Journal Article hSSB1 and hSSB2 Form Similar Multiprotein Complexes That Participate in DNA Damage ResponseYongjiang Li, Emma Bolderson, Rakesh Kumar, Parameswary A. Muniandy, Yutong Xue, Derek J. Richard, Michael Seidman, Tej K. Pandita, Kum Kum Khanna and Weidong Wang (2009). hSSB1 and hSSB2 Form Similar Multiprotein Complexes That Participate in DNA Damage Response. Journal of Biological Chemistry, 284 (35), 23525-23531.. doi: 10.1074/jbc.C109.039586 |
|
2009 Journal Article Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repairArun Gupta, Qin Yang, Raj K. Pandita, Clayton R. Hunt, Tao Xiang, Sandeep Misri, Sicong Zeng, Julia Pagan, Jessie Jeffery, Janusz Puc, Rakesh Kumar, Zhihui Feng, Simon N. Powell, Audesh Bhat, Tomoko Yaguchi, Renu Wadhwa, Sunil C. Kaul, Ramon Parsons, Kum Kum Khanna and Tej K. Pandita (2009). Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair. Cell Cycle, 8 (14), 2198-2210. doi: 10.4161/cc.8.14.8947 |
|
2009 Journal Article Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysisRichard, Derek J., Bolderson, Emma and Khanna, Kum Kum (2009). Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis. Critical Reviews in Biochemistry and Molecular Biology, 44 (2-3), 98-116. doi: 10.1080/10409230902849180 |
|
2009 Journal Article Involvement of Exo1b in DNA damage-induced apoptosisEmma Bolderson, Derek J. Richard, Winfried Edelmann and Kum Kum Khanna (2009). Involvement of Exo1b in DNA damage-induced apoptosis. Nucleic Acids Research, 37 (10), 3452-3463. doi: 10.1093/nar/gkp194 |
