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2021 Journal Article Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depressionMartin, Joanna, Asjadi, Kimiya, Hubbard, Leon, Kendall, Kimberley, Pardiñas, Antonio F., Jermy, Bradley, Lewis, Cathryn M., Baune, Bernhard T., Boomsma, Dorret I., Hamilton, Steven P., Lucae, Susanne, Magnusson, Patrik K., Martin, Nicholas G., McIntosh, Andrew M., Mehta, Divya, Mors, Ole, Mullins, Niamh, Penninx, Brenda W. J. H., Preisig, Martin, Rietschel, Marcella, Jones, Ian, Walters, James T. R., Rice, Frances, Thapar, Anita, O’Donovan, Michael and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2021). Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression. PLoS One, 16 (9) e0248254, e0248254. doi: 10.1371/journal.pone.0248254 |
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2021 Journal Article Genomic and phenotypic insights from an atlas of genetic effects on DNA methylationMin, Josine L., Hemani, Gibran, Hannon, Eilis, Dekkers, Koen F., Castillo-Fernandez, Juan, Luijk, René, Carnero-Montoro, Elena, Lawson, Daniel J., Burrows, Kimberley, Suderman, Matthew, Bretherick, Andrew D., Richardson, Tom G., Klughammer, Johanna, Iotchkova, Valentina, Sharp, Gemma, Al Khleifat, Ahmad, Shatunov, Aleksey, Iacoangeli, Alfredo, McArdle, Wendy L., Ho, Karen M., Kumar, Ashish, Söderhäll, Cilla, Soriano-Tárraga, Carolina, Giralt-Steinhauer, Eva, Kazmi, Nabila, Mason, Dan, McRae, Allan F., Corcoran, David L., Sugden, Karen ... BIOS Consortium (2021). Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation. Nature Genetics, 53 (9), 1311-1321. doi: 10.1038/s41588-021-00923-x |
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2021 Journal Article Neuropeptide S receptor 1 is a nonhormonal treatment target in endometriosisTapmeier, Thomas T., Rahmioglu, Nilufer, Lin, Jianghai, De Leo, Bianca, Obendorf, Maik, Raveendran, Muthuswamy, Fischer, Oliver M., Bafligil, Cemsel, Guo, Manman, Harris, Ronald Alan, Hess-Stumpp, Holger, Laux-Biehlmann, Alexis, Lowy, Ernesto, Lunter, Gerton, Malzahn, Jessica, Martin, Nicholas G., Martinez, Fernando O., Manek, Sanjiv, Mesch, Stefanie, Montgomery, Grant W., Morris, Andrew P., Nagel, Jens, Simmons, Heather A., Brocklebank, Denise, Shang, Catherine, Treloar, Susan, Wells, Graham, Becker, Christian M., Oppermann, Udo ... Zondervan, Krina T. (2021). Neuropeptide S receptor 1 is a nonhormonal treatment target in endometriosis. Science Translational Medicine, 13 (608) eabd6469, 1-12. doi: 10.1126/scitranslmed.abd6469 |
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2021 Journal Article Polygenic risk scores derived from varying definitions of depression and risk of depressionMitchell, Brittany L., Thorp, Jackson G., Wu, Yeda, Campos, Adrian I., Nyholt, Dale R., Gordon, Scott D., Whiteman, David C., Olsen, Catherine M., Hickie, Ian B., Martin, Nicholas G., Medland, Sarah E., Wray, Naomi R. and Byrne, Enda M. (2021). Polygenic risk scores derived from varying definitions of depression and risk of depression. JAMA Psychiatry, 78 (10), 1152-1160. doi: 10.1001/jamapsychiatry.2021.1988 |
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2021 Journal Article Phantom epistasis between unlinked lociHemani, Gibran, Powell, Joseph E., Wang, Huanwei, Shakhbazov, Konstantin, Westra, Harm-Jan, Esko, Tonu, Henders, Anjali K., McRae, Allan F., Martin, Nicholas G., Metspalu, Andres, Franke, Lude, Montgomery, Grant W., Goddard, Michael E., Gibson, Greg, Yang, Jian and Visscher, Peter M. (2021). Phantom epistasis between unlinked loci. Nature, 596 (7871), E1-E3. doi: 10.1038/s41586-021-03765-z |
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2021 Journal Article Genetic insights into biological mechanisms governing human ovarian ageingRuth, Katherine S., Day, Felix R., Hussain, Jazib, Martínez-Marchal, Ana, Aiken, Catherine E., Azad, Ajuna, Thompson, Deborah J., Knoblochova, Lucie, Abe, Hironori, Tarry-Adkins, Jane L., Gonzalez, Javier Martin, Fontanillas, Pierre, Claringbould, Annique, Bakker, Olivier B., Sulem, Patrick, Walters, Robin G., Terao, Chikashi, Turon, Sandra, Horikoshi, Momoko, Lin, Kuang, Onland-Moret, N. Charlotte, Sankar, Aditya, Hertz, Emil Peter Thrane, Timshel, Pascal N., Shukla, Vallari, Borup, Rehannah, Olsen, Kristina W., Aguilera, Paula, Ferrer-Roda, Mònica ... Perry, John R. B. (2021). Genetic insights into biological mechanisms governing human ovarian ageing. Nature, 596 (7872), 393-397. doi: 10.1038/s41586-021-03779-7 |
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2021 Journal Article Genetic susceptibility to pneumonia: a GWAS meta-analysis between the UK Biobank and FinnGenCampos, Adrian I., Kho, Pik, Vazquez-Prada, Karla X., García-Marín, Luis M., Martin, Nicholas G., Cuéllar-Partida, Gabriel and Rentería, Miguel E. (2021). Genetic susceptibility to pneumonia: a GWAS meta-analysis between the UK Biobank and FinnGen. Twin Research and Human Genetics, 24 (3) PII S183242742100027X, 145-154. doi: 10.1017/thg.2021.27 |
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2021 Journal Article Genetic association study of childhood aggression across raters, instruments, and ageIp, Hill F., van der Laan, Camiel M., Krapohl, Eva M. L., Brikell, Isabell, Sánchez-Mora, Cristina, Nolte, Ilja M., St Pourcain, Beate, Bolhuis, Koen, Palviainen, Teemu, Zafarmand, Hadi, Colodro-Conde, Lucía, Gordon, Scott, Zayats, Tetyana, Aliev, Fazil, Jiang, Chang, Wang, Carol A., Saunders, Gretchen, Karhunen, Ville, Hammerschlag, Anke R., Adkins, Daniel E., Border, Richard, Peterson, Roseann E., Prinz, Joseph A., Thiering, Elisabeth, Seppälä, Ilkka, Vilor-Tejedor, Natàlia, Ahluwalia, Tarunveer S., Day, Felix R., Hottenga, Jouke-Jan ... Boomsma, Dorret I. (2021). Genetic association study of childhood aggression across raters, instruments, and age. Translational Psychiatry, 11 (1) 413, 413. doi: 10.1038/s41398-021-01480-x |
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2021 Journal Article Genetic risk for chronic pain is associated with lower antidepressant effectiveness: converging evidence for a depression subtypeCampos, Adrián I., Ngo, Trung Thanh, Medland, Sarah E., Wray, Naomi R., Hickie, Ian B., Byrne, Enda M., Martin, Nicholas G. and Rentería, Miguel E. (2021). Genetic risk for chronic pain is associated with lower antidepressant effectiveness: converging evidence for a depression subtype. Australian and New Zealand Journal of Psychiatry, 56 (9) 00048674211031491, 1-10. doi: 10.1177/00048674211031491 |
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2021 Journal Article Ethnic Identity and Genome Wide Runs of HomozygosityFieder, Martin, Mitchell, Brittany L., Gordon, Scott, Huber, Susanne and Martin, Nicholas G. (2021). Ethnic Identity and Genome Wide Runs of Homozygosity. Behavior Genetics, 51 (4), 405-413. doi: 10.1007/s10519-021-10053-z |
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2021 Journal Article Using monozygotic twins to dissect common genes in posttraumatic stress disorder and migraineBainomugisa, Charlotte K., Sutherland, Heidi G., Parker, Richard, Mcrae, Allan F., Haupt, Larisa M., Griffiths, Lyn R., Heath, Andrew, Nelson, Elliot C., Wright, Margaret J., Hickie, Ian B., Martin, Nicholas G., Nyholt, Dale R. and Mehta, Divya (2021). Using monozygotic twins to dissect common genes in posttraumatic stress disorder and migraine. Frontiers in Neuroscience, 15 678350, 678350. doi: 10.3389/fnins.2021.678350 |
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2021 Journal Article Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biologyMullins, Niamh, Forstner, Andreas J., O'Connell, Kevin S., Coombes, Brandon, Coleman, Jonathan R I, Qiao, Zhen, Als, Thomas D., Bigdeli, Tim B., Børte, Sigrid, Bryois, Julien, Charney, Alexander W., Drange, Ole Kristian, Gandal, Michael J., Hagenaars, Saskia P., Ikeda, Masashi, Kamitaki, Nolan, Kim, Minsoo, Krebs, Kristi, Panagiotaropoulou, Georgia, Schilder, Brian M., Sloofman, Laura G., Steinberg, Stacy, Trubetskoy, Vassily, Winsvold, Bendik S., Won, Hong-Hee, Abramova, Liliya, Adorjan, Kristina, Agerbo, Esben, Al Eissa, Mariam ... Andreassen, Ole A. (2021). Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature genetics, 53 (6), 817-829. doi: 10.1038/s41588-021-00857-4 |
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2021 Journal Article Early expressions of psychopathology and risk associated with trans-diagnostic transition to mood and psychotic disorders in adolescents and young adultsScott, Jan, Crouse, Jacob J., Ho, Nicholas, Iorfino, Frank, Martin, Nicholas, Parker, Richard, McGrath, John, Gillespie, Nathan A., Medland, Sarah and Hickie, Ian B. (2021). Early expressions of psychopathology and risk associated with trans-diagnostic transition to mood and psychotic disorders in adolescents and young adults. PLoS ONE, 16 (6 June) e0252550, 1-17. doi: 10.1371/journal.pone.0252550 |
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2021 Journal Article Phenome-wide screening of GWAS data reveals the complex causal architecture of obesityGarcía-Marín, Luis M., Campos, Adrián I., Kho, Pik-Fang, Martin, Nicholas G., Cuéllar-Partida, Gabriel and Rentería, Miguel E. (2021). Phenome-wide screening of GWAS data reveals the complex causal architecture of obesity. Human Genetics, 140 (8), 1253-1265. doi: 10.1007/s00439-021-02298-9 |
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2021 Journal Article Correction to: The augmented Classical Twin Design: incorporating genome‐wide identity by descent sharing into twin studies in order to model violations of the equal environments assumptionHwang, Liang-Dar, Mitchell, Brittany L., Medland, Sarah E., Martin, Nicholas G., Neale, Michael C. and Evans, David M. (2021). Correction to: The augmented Classical Twin Design: incorporating genome‐wide identity by descent sharing into twin studies in order to model violations of the equal environments assumption. Behavior Genetics, 51 (4), 441-442. doi: 10.1007/s10519-021-10065-9 |
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2021 Journal Article Days out of role and somatic, anxious-depressive, hypo-manic, and psychotic-like symptom dimensions in a community sample of young adultsCrouse, Jacob J., Ho, Nicholas, Scott, Jan, Martin, Nicholas G., Couvy-Duchesne, Baptiste, Hermens, Daniel F., Parker, Richard, Gillespie, Nathan A., Medland, Sarah E. and Hickie, Ian B. (2021). Days out of role and somatic, anxious-depressive, hypo-manic, and psychotic-like symptom dimensions in a community sample of young adults. Translational Psychiatry, 11 (1) 285, 285. doi: 10.1038/s41398-021-01390-y |
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2021 Journal Article Typologies of illicit drug use in mid-adulthood: a quasi-longitudinal latent class analysis in a community-based sample of twinsDash, Genevieve F., Martin, Nicholas G., Agrawal, Arpana, Lynskey, Michael T. and Slutske, Wendy S. (2021). Typologies of illicit drug use in mid-adulthood: a quasi-longitudinal latent class analysis in a community-based sample of twins. Addiction, 116 (5), 1101-1112. doi: 10.1111/add.15225 |
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2021 Journal Article The association between genetically determined ABO blood types and major depressive disorderGarvert, Linda, Baune, Bernhard T, Berger, Klaus, Boomsma, Dorret I, Breen, Gerome, Greinacher, Andreas, Hamilton, Steven P, Levinson, Douglas F, Lewis, Cathryn M, Lucae, Susanne, Magnusson, Patrik K E, Martin, Nicholas G, McIntosh, Andrew M, Mors, Ole, Müller-Myhsok, Bertram, Penninx, Brenda W J H, Perlis, Roy H, Pistis, Giorgio, Potash, James B, Preisig, Martin, Rietschel, Marcella, Shi, Jianxin, Smoller, Jordan W, Tiemeier, Henning, Uher, Rudolf, Völker, Uwe, Völzke, Henry, Weissman, Myrna M, Grabe, Hans J and Van der Auwera, Sandra (2021). The association between genetically determined ABO blood types and major depressive disorder. Psychiatry Research, 299 113837, 113837. doi: 10.1016/j.psychres.2021.113837 |
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2021 Journal Article Epigenome-wide association study of thyroid function traits identifies novel associations of fT3 with KLF9 and DOT1LLafontaine, Nicole, Campbell, Purdey J., Castillo-Fernandez, Juan E., Mullin, Shelby, Lim, Ee Mun, Kendrew, Phillip, Lewer, Michelle, Brown, Suzanne J., Huang, Rae-Chi, Melton, Phillip E., Mori, Trevor A., Beilin, Lawrence J., Dudbridge, Frank, Spector, Tim D., Wright, Margaret J., Martin, Nicholas G., McRae, Allan F., Panicker, Vijay, Zhu, Gu, Walsh, John P., Bell, Jordana T. and Wilson, Scott G. (2021). Epigenome-wide association study of thyroid function traits identifies novel associations of fT3 with KLF9 and DOT1L. The Journal of Clinical Endocrinology and Metabolism, 106 (5), e2191-e2202. doi: 10.1210/clinem/dgaa975 |
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2021 Journal Article Symptom-level modelling unravels the shared genetic architecture of anxiety and depressionThorp, Jackson G., Campos, Adrian I., Grotzinger, Andrew D., Gerring, Zachary F., An, Jiyuan, Ong, Jue-Sheng, Wang, Wei, Shringarpure, Suyash, Byrne, Enda M., MacGregor, Stuart, Martin, Nicholas G., Medland, Sarah E., Middeldorp, Christel M. and Derks, Eske M. (2021). Symptom-level modelling unravels the shared genetic architecture of anxiety and depression. Nature Human Behaviour, 5 (10), 1432-1442. doi: 10.1038/s41562-021-01094-9 |
