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2024

Journal Article

Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts

Adams, Mark J., Thorp, Jackson G., Jermy, Bradley S., Kwong, Alex S. F., Kõiv, Kadri, Grotzinger, Andrew D., Nivard, Michel G., Marshall, Sally, Milaneschi, Yuri, Baune, Bernhard T., Müller-Myhsok, Bertram, Penninx, Brenda W. J. H., Boomsma, Dorret I., Levinson, Douglas F., Breen, Gerome, Pistis, Giorgio, Grabe, Hans J., Tiemeier, Henning, Berger, Klaus, Rietschel, Marcella, Magnusson, Patrik K., Uher, Rudolf, Hamilton, Steven P., Lucae, Susanne, Lehto, Kelli, Li, Qingqin S., Byrne, Enda M., Hickie, Ian B., Martin, Nicholas G. ... Derks, Eske M. (2024). Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts. Psychological Medicine, 1-10. doi: 10.1017/s0033291724001880

Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts

2024

Journal Article

Markers of positive affect and brain state synchrony discriminate melancholic from non-melancholic depression using naturalistic stimuli

Mosley, Philip E., van der Meer, Johan N., Hamilton, Lachlan H. W., Fripp, Jurgen, Parker, Stephen, Jeganathan, Jayson, Breakspear, Michael, Parker, Richard, Holland, Rebecca, Mitchell, Brittany L., Byrne, Enda, Hickie, Ian B., Medland, Sarah E., Martin, Nicholas G. and Cocchi, Luca (2024). Markers of positive affect and brain state synchrony discriminate melancholic from non-melancholic depression using naturalistic stimuli. Molecular Psychiatry. doi: 10.1038/s41380-024-02699-y

Markers of positive affect and brain state synchrony discriminate melancholic from non-melancholic depression using naturalistic stimuli

2024

Journal Article

Genetic neurodevelopmental clustering and dyslexia

Ciulkinyte, Austeja, Mountford, Hayley S., Fontanillas, Pierre, Aslibekyan, Stella, Auton, Adam, Babalola, Elizabeth, Bell, Robert K., Bielenberg, Jessica, Bowes, Jonathan, Bryc, Katarzyna, Chaudhary, Ninad S., Coker, Daniella, Das, Sayantan, DelloRusso, Emily, Elson, Sarah L., Eriksson, Nicholas, Filshtein, Teresa, Freyman, Will, Fuller, Zach, German, Chris, Granka, Julie M., Heilbron, Karl, Hernandez, Alejandro, Hicks, Barry, Hinds, David A., Jewett, Ethan M., Jiang, Yunxuan, Kukar, Katelyn, Kwong, Alan ... 23andMe Research Team (2024). Genetic neurodevelopmental clustering and dyslexia. Molecular Psychiatry. doi: 10.1038/s41380-024-02649-8

Genetic neurodevelopmental clustering and dyslexia

2024

Journal Article

Publisher Correction: Understanding the genetic complexity of puberty timing across the allele frequency spectrum

Kentistou, Katherine A., Kaisinger, Lena R., Stankovic, Stasa, Vaudel, Marc, Mendes de Oliveira, Edson, Messina, Andrea, Walters, Robin G., Liu, Xiaoxi, Busch, Alexander S., Helgason, Hannes, Thompson, Deborah J., Santoni, Federico, Petricek, Konstantin M., Zouaghi, Yassine, Huang-Doran, Isabel, Gudbjartsson, Daniel F., Bratland, Eirik, Lin, Kuang, Gardner, Eugene J., Zhao, Yajie, Jia, Raina Y., Terao, Chikashi, Riggan, Marjorie J., Bolla, Manjeet K., Yazdanpanah, Mojgan, Yazdanpanah, Nahid, Bradfield, Jonathan P., Broer, Linda, Campbell, Archie ... The China Kadoorie Biobank Collaborative Group (2024). Publisher Correction: Understanding the genetic complexity of puberty timing across the allele frequency spectrum. Nature Genetics, 56 (8), 1-2. doi: 10.1038/s41588-024-01857-w

Publisher Correction: Understanding the genetic complexity of puberty timing across the allele frequency spectrum

2024

Journal Article

Understanding the genetic complexity of puberty timing across the allele frequency spectrum

Kentistou, Katherine A., Kaisinger, Lena R., Stankovic, Stasa, Vaudel, Marc, Mendes de Oliveira, Edson, Messina, Andrea, Walters, Robin G., Liu, Xiaoxi, Busch, Alexander S., Helgason, Hannes, Thompson, Deborah J., Santoni, Federico, Petricek, Konstantin M., Zouaghi, Yassine, Huang-Doran, Isabel, Gudbjartsson, Daniel F., Bratland, Eirik, Lin, Kuang, Gardner, Eugene J., Zhao, Yajie, Jia, Raina Y., Terao, Chikashi, Riggan, Marjorie J., Bolla, Manjeet K., Yazdanpanah, Mojgan, Yazdanpanah, Nahid, Bradfield, Jonathan P., Broer, Linda, Campbell, Archie ... The China Kadoorie Biobank Collaborative Group (2024). Understanding the genetic complexity of puberty timing across the allele frequency spectrum. Nature Genetics, 56 (7), 1-15. doi: 10.1038/s41588-024-01798-4

Understanding the genetic complexity of puberty timing across the allele frequency spectrum

2024

Journal Article

Differential etiologic associations of heroin use and prescription opioid misuse with psychopathology

Dash, Genevieve F., Gizer, Ian R., Martin, Nicholas G. and Slutske, Wendy S. (2024). Differential etiologic associations of heroin use and prescription opioid misuse with psychopathology. Journal of Psychopathology and Clinical Science, 133 (5), 378-391. doi: 10.1037/abn0000921

Differential etiologic associations of heroin use and prescription opioid misuse with psychopathology

2024

Journal Article

Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder

Nievergelt, Caroline M., Maihofer, Adam X., Atkinson, Elizabeth G., Chen, Chia-Yen, Choi, Karmel W., Coleman, Jonathan R. I., Daskalakis, Nikolaos P., Duncan, Laramie E., Polimanti, Renato, Aaronson, Cindy, Amstadter, Ananda B., Andersen, Soren B., Andreassen, Ole A., Arbisi, Paul A., Ashley-Koch, Allison E., Austin, S. Bryn, Avdibegoviç, Esmina, Babić, Dragan, Bacanu, Silviu-Alin, Baker, Dewleen G., Batzler, Anthony, Beckham, Jean C., Belangero, Sintia, Benjet, Corina, Bergner, Carisa, Bierer, Linda M., Biernacka, Joanna M., Bierut, Laura J., Bisson, Jonathan I. ... HUNT All-In Psychiatry (2024). Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder. Nature Genetics, 56 (5), 792-808. doi: 10.1038/s41588-024-01707-9

Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder

2024

Journal Article

Patterns of stressful life events and polygenic scores for five mental disorders and neuroticism among adults with depression

Crouse, Jacob J., Park, Shin Ho, Byrne, Enda M., Mitchell, Brittany L., Scott, Jan, Medland, Sarah E., Lin, Tian, Wray, Naomi R., Martin, Nicholas G. and Hickie, Ian B. (2024). Patterns of stressful life events and polygenic scores for five mental disorders and neuroticism among adults with depression. Molecular Psychiatry, 29 (9), 1-9. doi: 10.1038/s41380-024-02492-x

Patterns of stressful life events and polygenic scores for five mental disorders and neuroticism among adults with depression

2024

Journal Article

Genetic control of DNA methylation is largely shared across European and East Asian populations

Hatton, Alesha A., Cheng, Fei-Fei, Lin, Tian, Shen, Ren-Juan, Chen, Jie, Zheng, Zhili, Qu, Jia, Lyu, Fan, Harris, Sarah E., Cox, Simon R., Jin, Zi-Bing, Martin, Nicholas G., Fan, Dongsheng, Montgomery, Grant W., Yang, Jian, Wray, Naomi R., Marioni, Riccardo E., Visscher, Peter M. and McRae, Allan F. (2024). Genetic control of DNA methylation is largely shared across European and East Asian populations. Nature Communications, 15 (1) 2713, 1-12. doi: 10.1038/s41467-024-47005-0

Genetic control of DNA methylation is largely shared across European and East Asian populations

2024

Journal Article

Comprehensive sex-stratified genetic analysis of 28 blood biomarkers and depression reveals a significant association between depression and low levels of total protein in females

Kiewa, Jacqueline, Meltzer-Brody, Samantha, Milgrom, Jeannette, Guintivano, Jerry, Hickie, Ian B, Whiteman, David C, Olsen, Catherine M, Medland, Sarah E, Martin, Nicholas G, Wray, Naomi R and Byrne, Enda M (2024). Comprehensive sex-stratified genetic analysis of 28 blood biomarkers and depression reveals a significant association between depression and low levels of total protein in females. Complex Psychiatry, 10 (1-4), 19-34. doi: 10.1159/000538058

Comprehensive sex-stratified genetic analysis of 28 blood biomarkers and depression reveals a significant association between depression and low levels of total protein in females

2024

Journal Article

Family History of Twinning and Fertility Traits in Nigerian Mothers of Dizygotic Twins

Hur, Yoon-Mi, Martin, Nick, Oginni, Olakunle, Boomsma, Dorret, Hubers, Nikki and Mbarek, Hamdi (2024). Family History of Twinning and Fertility Traits in Nigerian Mothers of Dizygotic Twins. Twin Research and Human Genetics, 27 (1), 1-6. doi: 10.1017/thg.2024.2

Family History of Twinning and Fertility Traits in Nigerian Mothers of Dizygotic Twins

2024

Journal Article

Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications

Sterenborg, Rosalie B. T. M., Steinbrenner, Inga, Li, Yong, Bujnis, Melissa N., Naito, Tatsuhiko, Marouli, Eirini, Galesloot, Tessel E., Babajide, Oladapo, Andreasen, Laura, Astrup, Arne, Åsvold, Bjørn Olav, Bandinelli, Stefania, Beekman, Marian, Beilby, John P., Bork-Jensen, Jette, Boutin, Thibaud, Brody, Jennifer A., Brown, Suzanne J., Brumpton, Ben, Campbell, Purdey J., Cappola, Anne R., Ceresini, Graziano, Chaker, Layal, Chasman, Daniel I., Concas, Maria Pina, Coutinho de Almeida, Rodrigo, Cross, Simone M., Cucca, Francesco, Deary, Ian J. ... Regeneron Genetics Center (2024). Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications. Nature Communications, 15 (1) 888, 1-18. doi: 10.1038/s41467-024-44701-9

Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications

2024

Journal Article

X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements

Scholz, Markus, Horn, Katrin, Pott, Janne, Wuttke, Matthias, Kühnapfel, Andreas, Nasr, M. Kamal, Kirsten, Holger, Li, Yong, Hoppmann, Anselm, Gorski, Mathias, Ghasemi, Sahar, Li, Man, Tin, Adrienne, Chai, Jin-Fang, Cocca, Massimiliano, Wang, Judy, Nutile, Teresa, Akiyama, Masato, Åsvold, Bjørn Olav, Bansal, Nisha, Biggs, Mary L., Boutin, Thibaud, Brenner, Hermann, Brumpton, Ben, Burkhardt, Ralph, Cai, Jianwen, Campbell, Archie, Campbell, Harry, Chalmers, John ... Pattaro, Cristian (2024). X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements. Nature Communications, 15 (1) 586, 1-17. doi: 10.1038/s41467-024-44709-1

X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements

2024

Journal Article

Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference

Meng, Xiangrui, Navoly, Georgina, Giannakopoulou, Olga, Levey, Daniel F., Koller, Dora, Pathak, Gita A., Koen, Nastassja, Lin, Kuang, Adams, Mark J., Rentería, Miguel E., Feng, Yanzhe, Gaziano, J. Michael, Stein, Dan J., Zar, Heather J., Campbell, Megan L., van Heel, David A., Trivedi, Bhavi, Finer, Sarah, McQuillin, Andrew, Bass, Nick, Chundru, V. Kartik, Martin, Hilary C., Huang, Qin Qin, Valkovskaya, Maria, Chu, Chia-Yi, Kanjira, Susan, Kuo, Po-Hsiu, Chen, Hsi-Chung, Tsai, Shih-Jen ... BioBank Japan Project (2024). Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference. Nature Genetics, 56 (2), 222-233. doi: 10.1038/s41588-023-01596-4

Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference

2024

Journal Article

Investigating the genetic relationship of intracranial and subcortical brain volumes with depression and other psychiatric disorders

García-Marín, Luis M., Ogonowski, Natalia S., Han, Laura K.M., Maya-Martínez, Mateo, Mitchell, Brittany L., Schmaal, Lianne, Martin, Nicholas G. and Rentería, Miguel E. (2024). Investigating the genetic relationship of intracranial and subcortical brain volumes with depression and other psychiatric disorders. Imaging Neuroscience, 2, 1-16. doi: 10.1162/imag_a_00291

Investigating the genetic relationship of intracranial and subcortical brain volumes with depression and other psychiatric disorders

2024

Journal Article

Evening chronotypes with depression report poorer outcomes of SSRIs: A survey-based study of self-ratings

Crouse, Jacob J., Park, Shin Ho, Byrne, Enda M., Mitchell, Brittany L., Chan, Karina, Scott, Jan, Medland, Sarah E., Martin, Nicholas G., Wray, Naomi R. and Hickie, Ian B. (2024). Evening chronotypes with depression report poorer outcomes of SSRIs: A survey-based study of self-ratings. Biological Psychiatry, 96 (1), 4-14. doi: 10.1016/j.biopsych.2023.12.023

Evening chronotypes with depression report poorer outcomes of SSRIs: A survey-based study of self-ratings

2024

Journal Article

Dyslexia polygenic scores show heightened prediction of verbal working memory and arithmetic

Perugini, Ambra, Fontanillas, Pierre, Gordon, Scott D., Fisher, Simon E., Martin, Nicholas G., Bates, Timothy C and Luciano, Michelle (2024). Dyslexia polygenic scores show heightened prediction of verbal working memory and arithmetic. Scientific Studies of Reading, 28 (5), 1-15. doi: 10.1080/10888438.2024.2365697

Dyslexia polygenic scores show heightened prediction of verbal working memory and arithmetic

2024

Journal Article

Genetic and shared environmental factors explain the association between adolescent polysubstance use and high school noncompletion

Davis, Christal N., Gizer, Ian R., Agrawal, Arpana, Statham, Dixie J., Heath, Andrew C., Martin, Nicholas G. and Slutske, Wendy S. (2024). Genetic and shared environmental factors explain the association between adolescent polysubstance use and high school noncompletion. Psychology of Addictive Behaviors, 38 (1), 114-123. doi: 10.1037/adb0000915

Genetic and shared environmental factors explain the association between adolescent polysubstance use and high school noncompletion

2024

Journal Article

Genome-wide association study meta-analysis of dizygotic twinning illuminates genetic regulation of female fecundity

Mbarek, Hamdi, Gordon, Scott D., Duffy, David L., Hubers, Nikki, Mortlock, Sally, Beck, Jeffrey J., Hottenga, Jouke-Jan, Pool, René, Dolan, Conor V., Actkins, Ky’Era V., Gerring, Zachary F., Van Dongen, Jenny, Ehli, Erik A., Iacono, William G., Mcgue, Matt, Chasman, Daniel I., Gallagher, C. Scott, Schilit, Samantha L. P., Morton, Cynthia C., Paré, Guillaume, Willemsen, Gonneke, Whiteman, David C., Olsen, Catherine M., Derom, Catherine, Vlietinck, Robert, Gudbjartsson, Daniel, Cannon-Albright, Lisa, Krapohl, Eva, Plomin, Robert ... Martin, Nicholas G. (2024). Genome-wide association study meta-analysis of dizygotic twinning illuminates genetic regulation of female fecundity. Human Reproduction, 39 (1), 240-257. doi: 10.1093/humrep/dead247

Genome-wide association study meta-analysis of dizygotic twinning illuminates genetic regulation of female fecundity

2023

Journal Article

Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals

Zhou, Hang, Kember, Rachel L., Deak, Joseph D., Xu, Heng, Toikumo, Sylvanus, Yuan, Kai, Lind, Penelope A., Farajzadeh, Leila, Wang, Lu, Hatoum, Alexander S., Johnson, Jessica, Lee, Hyunjoon, Mallard, Travis T., Xu, Jiayi, Johnston, Keira J. A., Johnson, Emma C., Nielsen, Trine Tollerup, Galimberti, Marco, Dao, Cecilia, Levey, Daniel F., Overstreet, Cassie, Byrne, Enda M., Gillespie, Nathan A., Gordon, Scott, Hickie, Ian B., Whitfield, John B., Xu, Ke, Zhao, Hongyu, Huckins, Laura M. ... Million Veteran Program (2023). Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals. Nature Medicine, 29 (12), 3184-3192. doi: 10.1038/s41591-023-02653-5

Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals