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2026 Journal Article Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signalingStrom, Nora I., Verhulst, Brad, Bacanu, Silviu-Alin, Cheesman, Rosa, Purves, Kirstin L., Gedik, Hüseyin, Mitchell, Brittany L., Kwong, Alex S., Faucon, Annika B., Singh, Kritika, Medland, Sarah, Colodro-Conde, Lucia, Krebs, Kristi, Hoffmann, Per, Herms, Stefan, Gehlen, Jan, Ripke, Stephan, Awasthi, Swapnil, Palviainen, Teemu, Tasanko, Elisa M., Peterson, Roseann E., Adkins, Daniel E., Shabalin, Andrey A., Adams, Mark J., Iveson, Matthew H., Campbell, Archie, Thomas, Laurent F., Winsvold, Bendik S., Drange, Ole Kristian ... Hettema, John M. (2026). Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling. Nature Genetics, 58 (2), 1-14. doi: 10.1038/s41588-025-02485-8 |
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2026 Journal Article Insights from a cross-sectional population-based study of 10,929 Australians living with Parkinson's disease: risk factors, comorbidities, and sex differencesCao, Fangyuan, McAloney, Kerrie, Ogonowski, Natalia S., García-Marín, Luis M., Díaz-Torres, Santiago, Flores-Ocampo, Victor, Ceja, Zuriel, Chafota, Freddy, Parker, Richard, Ferguson, Mary, Cicero, Rebekah A., List-Armitage, Susan E., Miller, Vicki, Campbell, Clyde, Sue, Carolyn M., Kumar, Kishore R., Mellick, George D., Martin, Nicholas G. and Rentería, Miguel E. (2026). Insights from a cross-sectional population-based study of 10,929 Australians living with Parkinson's disease: risk factors, comorbidities, and sex differences. The Lancet Regional Health - Western Pacific, 68 101816, 101816. doi: 10.1016/j.lanwpc.2026.101816 |
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2026 Journal Article Genetic and Phenotypic Associations With Sustained Antidepressant Use in Major Depressive DisorderWalker, Alicia, Mitchell, Brittany L., Lin, Tian, Crouse, Jacob J., Albinana, Clara, Yap, Chloe X., Lynall, Mary Ellen, Lind, Penelope A., Cipriani, Andrea, Byrne, Enda M., Medland, Sarah E., Martin, Nicholas G., Taquet, Maxime, Hickie, Ian B. and Wray, Naomi R. (2026). Genetic and Phenotypic Associations With Sustained Antidepressant Use in Major Depressive Disorder. Jama Psychiatry, 83 (3), 247-258. doi: 10.1001/jamapsychiatry.2025.4372 |
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2026 Journal Article Trans-ancestry GWAS of hot flashes reveals potent treatment target and overlap with psychiatric disordersWerwath, Kathryn E., Lawn, Rebecca B., Salem, Madeleine T., Li, Tayden, Mitchell, Brittany L., Shen, Hanyang, Gordon, Scott D., Kung, Benson, Stafford, Ciera, Vemuri, Mytilee, Ratanatharathorn, Andrew, Meijsen, Joeri, Shadyab, Aladdin H., Kooperberg, Charles, Koenen, Karestan C., Crandall, Carolyn J., Martin, Nicholas G. and Duncan, Laramie E. (2026). Trans-ancestry GWAS of hot flashes reveals potent treatment target and overlap with psychiatric disorders. Communications Medicine, 6 (1) 51, 51. doi: 10.1038/s43856-025-01305-8 |
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2026 Journal Article Genetic and environmental effects on weight gain from young adulthood to old age and its association with body mass index in early young adulthood: an individual-based pooled analysis of 16 twin cohortsObeso, Alvaro, Drouard, Gabin, Jelenkovic, Aline, Ordoñana, Juan R., Sánchez-Romera, Juan F., Colodro-Conde, Lucía, Ollikainen, Miina, Aaltonen, Sari, Corley, Robin P., Huibregtse, Brooke M., Medda, Emanuela, Fagnani, Corrado, Toccaceli, Virgilia, Gatz, Margaret, Butler, David A., Bartels, Meike, Ligthart, Lannie, de Geus, Eco JC, Christensen, Kaare, Skytthe, Axel, Kyvik, Kirsten O., Medland, Sarah E., Gordon, Scott D., Rasmussen, Finn E., Tynelius, Per, Franz, Carol E., Kremen, William S., Lyons, Michael J., Spector, Timothy ... Silventoinen, Karri (2026). Genetic and environmental effects on weight gain from young adulthood to old age and its association with body mass index in early young adulthood: an individual-based pooled analysis of 16 twin cohorts. International Journal of Obesity, 50 (4), 768-776. doi: 10.1038/s41366-025-01998-w |
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2026 Journal Article Atypical Depression Is Associated With a Distinct Clinical, Neurobiological, Treatment Response, and Polygenic Risk ProfileShin, Mirim, Crouse, Jacob J., Lin, Tian, Byrne, Enda M., Mitchell, Brittany L., Lind, Penelope A., Parker, Richard, Mckenna, Sarah, Tonini, Emiliana, Carpenter, Joanne S., Merikangas, Kathleen R., Wray, Naomi R., Medland, Sarah E., Martin, Nicholas G. and Hickie, Ian B. (2026). Atypical Depression Is Associated With a Distinct Clinical, Neurobiological, Treatment Response, and Polygenic Risk Profile. Biological Psychiatry. doi: 10.1016/j.biopsych.2026.01.003 |
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2026 Journal Article Leisure activity engagement and depressive symptoms: meta-analysis of 11 studies of middle-aged and older twins aged 32-99Nygaard, Marianne, Mosing, Miriam A., Finkel, Deborah G., Franz, Carol E., Kremen, William S., Martin, Nicholas G., Plassman, Brenda L., Reynolds, Chandra A., Sachdev, Perminder S., Thalamuthu, Anbupalam, Walters, Ellen E., Christensen, Kaare, Pedersen, Nancy L., Gatz, Margaret, McGue, Matt and IGEMS Consortium (2026). Leisure activity engagement and depressive symptoms: meta-analysis of 11 studies of middle-aged and older twins aged 32-99. The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 81 (1) glaf253. doi: 10.1093/gerona/glaf253 |
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2025 Journal Article The Interplay of Genes and Environment Across Multiple Studies (IGEMS) Consortium After Fifteen YearsFinkel, Deborah, Finch, Brian K., Gatz, Margaret, Christensen, Kaare, Franz, Carol E., Karlsson, Ida K., Kremen, William S., Krueger, Robert F., Lupton, Michelle, Martin, Nicholas, McGue, Matt, Mosing, Miriam A., Neiderhiser, Jenae, Nygaard, Marianne, Prom-Worley, Elizabeth, Reynolds, Chandra, Sachdev, Perminder, Sillanpää, Elina, Vuoksimaa, Eero, Whitfield, Keith E., Hayden, Orla, Walters, Ellen, Pedersen, Nancy L. and for the IGEMS consortium (2025). The Interplay of Genes and Environment Across Multiple Studies (IGEMS) Consortium After Fifteen Years. Twin Research and Human Genetics, 1-10. doi: 10.1017/thg.2025.10036 |
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2025 Journal Article Predicting adolescent disordered eating and behaviours: exploring environmental moderators of polygenic riskCurtis, Madeleine, Colodro‐Conde, Lucia, Medland, Sarah E., Gordon, Scott, Martin, Nicholas G., Wade, Tracey D. and Cohen‐Woods, Sarah (2025). Predicting adolescent disordered eating and behaviours: exploring environmental moderators of polygenic risk. Journal of Child Psychology and Psychiatry, 66 (12), 1795-1806. doi: 10.1111/jcpp.70012 |
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2025 Conference Publication Online Cognitive Testing for the Assessment of Alzheimer's Disease Risk and Early Disease StagesGomez, Lina, Flint, Jonny P., Adsett, Jessica, McAloney, Kerrie, Thienel, Renate, Borne, Léonie, Faucher, Caroline, Robinson, Gail, Martin, Nicholas G., Breakspear, Michael J. and Lupton, Michelle K. (2025). Online Cognitive Testing for the Assessment of Alzheimer's Disease Risk and Early Disease Stages. Alzheimer's Association International Conference (AAIC) 2025, Toronto, Canada, 27-31 July 2025. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1002/alz70856_099508 |
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2025 Journal Article Genome-wide meta-analyses of non-response to antidepressants provide insights into underlying molecular genetics and suggest potential pharmacotherapiesKoch, Elise, Puusepp, Tuuli, Einarsson, Guðmundur, Mitchell, Brittany L., Harder, Arvid, Lin, Yuhao, García-Marín, Luis M., Krebs, Kristi, Shadrin, Alexey A., Xiong, Ying, Estonian Biobank Research Team, Metspalu, Andres, Esko, Tõnu, Mägi, Reedik, Nelis, Mari, Hudjashov, Georgi, Frei, Oleksandr, Lu, Yi, Hägg, Sara, Rentería, Miguel E., Medland, Sarah E., Wray, Naomi R., Martin, Nicholas G., Hübel, Christopher, Breen, Gerome, Thorgeirsson, Thorgeir, Stefánsson, Hreinn, Stefánsson, Kári, Lehto, Kelli ... O’Connell, Kevin S. (2025). Genome-wide meta-analyses of non-response to antidepressants provide insights into underlying molecular genetics and suggest potential pharmacotherapies. Molecular Psychiatry, 31 (4), 2005-2013. doi: 10.1038/s41380-025-03357-7 |
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2025 Journal Article Unravelling the causal link between gut microbiota and acne risk using a genetic approachCao, Fangyuan, Ogonowski, Natalia S., Díaz-Torres, Santiago, Mitchell, Brittany L., Gharhakhani, Puya, Martin, Nicholas G., Simpson, Michael A., Ong, Jue-Sheng and Rentería, Miguel E. (2025). Unravelling the causal link between gut microbiota and acne risk using a genetic approach. Skin Health and Disease, 5 (6), 448-459. doi: 10.1093/skinhd/vzaf077 |
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2025 Journal Article Self-rated health and mortality: family background and genetic precursorsFinch, Brian Karl, Finkel, Deborah, Gatz, Margaret, Pedersen, Nancy L., Reynolds, Chandra A., Sachdev, Perminder, Selwood, Amanda, Martin, Nick and Mosing, Miriam A. (2025). Self-rated health and mortality: family background and genetic precursors. Discover Social Science and Health, 5 (1) 139. doi: 10.1007/s44155-025-00290-6 |
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2025 Conference Publication Heterogeneity of major depressive disorder investigated through sustained fill of specific antidepressant scriptsWalker, Alicia, Mitchell, Brittany, Lin, Tian, Crouse, Jacob, Martin, Nick, Taquet, Maxime, Medland, Sarah E., Hickie, Ian and Wray, Naomi (2025). Heterogeneity of major depressive disorder investigated through sustained fill of specific antidepressant scripts. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.504 |
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2025 Conference Publication Genome-wide association meta-analysis of identical depression phenotyping in 404,540 individualsWang, Rujia, Huider, Floris, Merola, Giuseppe Pierpaolo, Thomas, Jodi T., Kwong, Alex S.F., Adams, Mark, Zvrskovec, Johan, Coleman, Jonathan R.I., McIntosh, Andrew, Martin, Nicholas G., Penninx, Brenda WJH, Eley, Thalia C., Mitchell, Brittany, Boomsma, Dorret I. and Breen, Gerome (2025). Genome-wide association meta-analysis of identical depression phenotyping in 404,540 individuals. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 September 2023. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.167 |
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2025 Conference Publication Brain region-specific genetic architecture of suicidal ideation and attempt: insights from stratified LDSC, SMR, and functional enrichment analysesCeja, Zuriel, Edwards, Alexis, Martin, Nick, Medland, Sarah E. and Rentería, Miguel E. (2025). Brain region-specific genetic architecture of suicidal ideation and attempt: insights from stratified LDSC, SMR, and functional enrichment analyses. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.283 |
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2025 Conference Publication Unravelling sex differences in the genetic architecture of anxiety: a genome-wide association study in the UK biobankHu, Jihua, Lupton, Michelle, Byrne, Enda M., Martin, Nicholas G., Whiteman, David, Olsen, Catherine, Thomas, Jodi, Medland, Sarah E., Grasby, Katrina and Mitchell, Brittany (2025). Unravelling sex differences in the genetic architecture of anxiety: a genome-wide association study in the UK biobank. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.288 |
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2025 Conference Publication Polygenic scores for eating disorders as a putative predictor for suicide behaviourAguilar-Roldan, Aura, Ceja, Zuriel, Medland, Sarah E., Martin, Nick and Rentería, Miguel E. (2025). Polygenic scores for eating disorders as a putative predictor for suicide behaviour. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.564 |
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2025 Conference Publication Causal effects of cannabis use on depression and psychosis: integrating genetic and longitudinal methodsPasman, Joëlle, Tunez, Adria, Zonneveld, Tessa, Wesseldijk, Laura, Marsden, Sinan, Abellaoui, Abdel, ten Have, Margreet, Luik, Annemarie, Rutten, Bart, Gülöksüz, Sinan, van Os, Jim, Lind, Penelope, Martin, Nicholas, Treur, Jorien and Verweij, Karin (2025). Causal effects of cannabis use on depression and psychosis: integrating genetic and longitudinal methods. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.302 |
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2025 Journal Article Genetic overlap between DSM-IV major depressive disorder and suicidal behaviors: evidence from polygenic risk scores in young adult twinsGillespie, Nathan A., Su, Mei-Hsin, Lannoy, Séverine, Stephenson, Mallory, Rentería, Miguel E., Ceja, Zuriel, Hickie, Ian B., Martin, Nicholas G. and Edwards, Alexis C. (2025). Genetic overlap between DSM-IV major depressive disorder and suicidal behaviors: evidence from polygenic risk scores in young adult twins. Behavior Genetics, 55 (6), 423-437. doi: 10.1007/s10519-025-10234-0 |
