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2025 Conference Publication Online Cognitive Testing for the Assessment of Alzheimer's Disease Risk and Early Disease StagesGomez, Lina, Flint, Jonny P., Adsett, Jessica, McAloney, Kerrie, Thienel, Renate, Borne, Léonie, Faucher, Caroline, Robinson, Gail, Martin, Nicholas G., Breakspear, Michael J. and Lupton, Michelle K. (2025). Online Cognitive Testing for the Assessment of Alzheimer's Disease Risk and Early Disease Stages. Alzheimer's Association International Conference (AAIC) 2025, Toronto, Canada, 27-31 July 2025. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1002/alz70856_099508 |
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2025 Journal Article Self-rated health and mortality: family background and genetic precursorsFinch, Brian Karl, Finkel, Deborah, Gatz, Margaret, Pedersen, Nancy L., Reynolds, Chandra A., Sachdev, Perminder, Selwood, Amanda, Martin, Nick and Mosing, Miriam A. (2025). Self-rated health and mortality: family background and genetic precursors. Discover Social Science and Health, 5 (1) 139. doi: 10.1007/s44155-025-00290-6 |
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2025 Conference Publication Unravelling sex differences in the genetic architecture of anxiety: a genome-wide association study in the UK biobankHu, Jihua, Lupton, Michelle, Byrne, Enda M., Martin, Nicholas G., Whiteman, David, Olsen, Catherine, Thomas, Jodi, Medland, Sarah E., Grasby, Katrina and Mitchell, Brittany (2025). Unravelling sex differences in the genetic architecture of anxiety: a genome-wide association study in the UK biobank. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.288 |
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2025 Conference Publication Polygenic scores for eating disorders as a putative predictor for suicide behaviourAguilar-Roldan, Aura, Ceja, Zuriel, Medland, Sarah E., Martin, Nick and Rentería, Miguel E. (2025). Polygenic scores for eating disorders as a putative predictor for suicide behaviour. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.564 |
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2025 Conference Publication Causal effects of cannabis use on depression and psychosis: integrating genetic and longitudinal methodsPasman, Joëlle, Tunez, Adria, Zonneveld, Tessa, Wesseldijk, Laura, Marsden, Sinan, Abellaoui, Abdel, ten Have, Margreet, Luik, Annemarie, Rutten, Bart, Gülöksüz, Sinan, van Os, Jim, Lind, Penelope, Martin, Nicholas, Treur, Jorien and Verweij, Karin (2025). Causal effects of cannabis use on depression and psychosis: integrating genetic and longitudinal methods. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.302 |
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2025 Conference Publication Heterogeneity of major depressive disorder investigated through sustained fill of specific antidepressant scriptsWalker, Alicia, Mitchell, Brittany, Lin, Tian, Crouse, Jacob, Martin, Nick, Taquet, Maxime, Medland, Sarah E., Hickie, Ian and Wray, Naomi (2025). Heterogeneity of major depressive disorder investigated through sustained fill of specific antidepressant scripts. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.504 |
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2025 Conference Publication Genome-wide association meta-analysis of identical depression phenotyping in 404,540 individualsWang, Rujia, Huider, Floris, Merola, Giuseppe Pierpaolo, Thomas, Jodi T., Kwong, Alex S.F., Adams, Mark, Zvrskovec, Johan, Coleman, Jonathan R.I., McIntosh, Andrew, Martin, Nicholas G., Penninx, Brenda WJH, Eley, Thalia C., Mitchell, Brittany, Boomsma, Dorret I. and Breen, Gerome (2025). Genome-wide association meta-analysis of identical depression phenotyping in 404,540 individuals. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 September 2023. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.167 |
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2025 Conference Publication Brain region-specific genetic architecture of suicidal ideation and attempt: insights from stratified LDSC, SMR, and functional enrichment analysesCeja, Zuriel, Edwards, Alexis, Martin, Nick, Medland, Sarah E. and Rentería, Miguel E. (2025). Brain region-specific genetic architecture of suicidal ideation and attempt: insights from stratified LDSC, SMR, and functional enrichment analyses. World Congress of Psychiatric Genetics (WCPG), Cancun, Mexico, 19-23 October 2025. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2025.08.283 |
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2025 Journal Article Life without sex: large-scale study links sexlessness to physical, cognitive, and personality traits, socioecological factors, and DNAAbdellaoui, Abdel, Wesseldijk, Laura W., Gordon, Scott D., Pasman, Joëlle A., Smit, Dirk J. A., Androvičová, Renáta, Martin, Nicholas G., Ullén, Fredrik, Mosing, Miriam A., Zietsch, Brendan P. and Verweij, Karin J. H. (2025). Life without sex: large-scale study links sexlessness to physical, cognitive, and personality traits, socioecological factors, and DNA. Proceedings of the National Academy of Sciences, 122 (38) e2418257122, e2418257122-38. doi: 10.1073/pnas.2418257122 |
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2025 Journal Article Sex-stratified genome-wide association meta-analysis of major depressive disorderThomas, Jodi T., Thorp, Jackson G., Huider, Floris, Grimes, Poppy Z., Wang, Rujia, Youssef, Pierre, Coleman, Jonathan R. I., Byrne, Enda M., Adams, Mark, BIONIC consortium, van Loo, Hanna M., Penninx, Brenda W. J. H., The GLAD Study, Medland, Sarah E., Hickie, Ian B., Olsen, Catherine M., Whiteman, David C., Whalley, Heather C., Penninx, Brenda W.J.H., van Loo, Hanna M., Derks, Eske M., Eley, Thalia C., Breen, Gerome, Boomsma, Dorret I., Wray, Naomi R., Martin, Nicholas G. and Mitchell, Brittany L. (2025). Sex-stratified genome-wide association meta-analysis of major depressive disorder. Nature Communications, 16 (1) 7960, 7960. doi: 10.1038/s41467-025-63236-1 |
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2025 Journal Article Large-scale GWAS of strabismus identifies risk loci and provides support for a link with maternal smokingHe, Weixiong, van der Most, Peter J., Ong, Jue-Sheng, Hwang, Liang-Dar, Wu, Yeda, Magnø, Morten S., Vehof, Jelle, Krebs, Kristi, Mauring, Laura, Õunap, Katrin, Abner, Erik, Martin, Nicholas G., Plotnikov, Denis, Jiang, Chen, Melles, Ronald B., Gharahkhani, Puya, Snieder, Harold, Palumaa, Teele, Kaljurand, Kuldar, Guggenheim, Jeremy A., Mackey, David A., Engle, Elizabeth C., Choquet, Hélène, MacGregor, Stuart, Lifelines Cohort Study, Aguirre-Gamboa, Raul, Deelen, Patrick, Franke, Lude, Kuivenhoven, Jan A. ... Wray, Naomi (2025). Large-scale GWAS of strabismus identifies risk loci and provides support for a link with maternal smoking. Nature Communications, 16 (1) 7890, 1-14. doi: 10.1038/s41467-025-62456-9 |
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2025 Journal Article Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traitsJohnson, Emma C., Lai, Dongbing, Balbona, Jared V., Miller, Alex P., Hatoum, Alexander S., Deak, Joseph D., Jennings, Mariela, Baranger, David A. A., Galimberti, Marco, Sanichwankul, Kittipong, Thorgeirsson, Thorgeir, Colbert, Sarah M. C., Adhikari, Keyrun, Docherty, Anna R., Degenhardt, Louisa, Edwards, Tobias, Fox, Louis, Giannelis, Alexandros, Jeffries, Paul W., Korhonen, Tellervo, Morrison, Claire L., Nunez, Yaira Z., Palviainen, Teemu, Su, Mei-Hsin, Romero Villela, Pamela N., Wetherill, Leah, Willoughby, Emily A., Zellers, Stephanie M., Bierut, Laura J. ... Agrawal, Arpana (2025). Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits. Psychological Medicine, 55 e234, e234. doi: 10.1017/S0033291725100883 |
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2025 Journal Article Multivariate genome-wide association analysis of dyslexia and quantitative reading skill improves gene discoveryMountford, Hayley S., Eising, Else, Fontanillas, Pierre, Auton, Adam, 23andMe Research Team, Aslibekyan, Stella, Bell, Robert K., Kukar Bond, Katelyn, Cochinwala, Zayn, Das, Sayantan, de Brito, Kahsaia, DelloRusso, Emily, Eijsbouts, Chris, Elson, Sarah L., German, Chris, Granka, Julie M., Hicks, Barry, Hinds, David A., Jabal, Reza, Khan, Aly, Kmiecik, Matthew J., Kwong, Alan, Liang, Yanyu, Lin, Keng-Han, McIntyre, Matthew H., Saini, Shubham, Shastri, Anjali J., Shi, Jingchunzi, Shringarpure, Suyash ... Luciano, Michelle (2025). Multivariate genome-wide association analysis of dyslexia and quantitative reading skill improves gene discovery. Translational Psychiatry, 15 (1) 289, 289-1. doi: 10.1038/s41398-025-03514-0 |
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2025 Journal Article Uncovering the multivariate genetic architecture of frailty with genomic structural equation modelingFoote, Isabelle F., Flint, Jonny P., Fürtjes, Anna E., Lawrence, Jeremy M., Mullin, Donncha S., Fisk, John D., Karakach, Tobias K., Rutenberg, Andrew, Martin, Nicholas G., Lupton, Michelle K., Llewellyn, David J., Ranson, Janice M., Cox, Simon R., Luciano, Michelle, Rockwood, Kenneth and Grotzinger, Andrew D. (2025). Uncovering the multivariate genetic architecture of frailty with genomic structural equation modeling. Nature Genetics, 57 (8), 1848-1859. doi: 10.1038/s41588-025-02269-0 |
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2025 Journal Article Predicting adolescent disordered eating and behaviours: exploring environmental moderators of polygenic riskCurtis, Madeleine, Colodro‐Conde, Lucia, Medland, Sarah E., Gordon, Scott, Martin, Nicholas G., Wade, Tracey D. and Cohen‐Woods, Sarah (2025). Predicting adolescent disordered eating and behaviours: exploring environmental moderators of polygenic risk. Journal of Child Psychology and Psychiatry, 66 (12) jcpp.70012, 1795-1806. doi: 10.1111/jcpp.70012 |
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2025 Journal Article Exploring the Relationship between Polygenic Scores, Community-Shared Socioeconomic Indicators and Major Depressive Disorder OutcomeSepulveda, Dante T., Thorp, Jackson G., Lind, Penelope A., Martin, Nicholas G., Medland, Sarah E. and Mitchell, Brittany L. (2025). Exploring the Relationship between Polygenic Scores, Community-Shared Socioeconomic Indicators and Major Depressive Disorder Outcome. Twin Research and Human Genetics, 28 (3), 1-9. doi: 10.1017/thg.2025.10011 |
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2025 Conference Publication Acne polygenic risk score derived from genome-wide association metaregression enables prediction of severityDu-Harpur, Xinyi, Maxwell, Jessye, Mitchell, Brittany L., Pardo, Luba M, Witkam, Willemijn C. A. M., Dand, Nick, Bartels, Meike, Betti, Michael, Boomsma, Dorret I., Dong, Xianjun, Gerring, Zachary, Finer, Sarah, Hagenbeek, Fiona A., Hottenga, Jouke Jan, Hripcsak, George, Huilaja, Laura, Hveem, Kristian, Jacobs, Benjamin, Kals, Mart, Kaufman-Cook, James, Kettunen, Johannes, Khan, Atlas, Kingo, Kulli, Kiryluk, Krzysztof, Løset, Mari, Lunter, Gerton, Lupton, Michelle, Min, Josine L., Martin, Nicholas G. ... Simpson, Michael A. (2025). Acne polygenic risk score derived from genome-wide association metaregression enables prediction of severity. 105th Annual Meeting of the British Association of Dermatologists, Glasgow, United Kingdom, 1-3 July 2025. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/bjd/ljaf085.025 |
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2025 Journal Article Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypesAssary, Elham, Coleman, Jonathan R. I., Hemani, Gibran, van de Weijer, Margot P., Howe, Laurence J., Palviainen, Teemu, Grasby, Katrina L., Ahlskog, Rafael, Nygaard, Marianne, Cheesman, Rosa, Lim, Kai, Reynolds, Chandra A., Ordoñana, Juan R., Colodro-Conde, Lucia, Gordon, Scott, Madrid-Valero, Juan J., Thalamuthu, Anbupalam, Hottenga, Jouke-Jan, Mengel-From, Jonas, Armstrong, Nicola J., Sachdev, Perminder S., Lee, Teresa, Brodaty, Henry, Trollor, Julian N., Wright, Margaret, Ames, David, Catts, Vibeke S., Latvala, Antti, The Within Family Consortium ... Keers, Robert (2025). Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes. Nature Human Behaviour, 9 (8), 1-14. doi: 10.1038/s41562-025-02193-7 |
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2025 Journal Article The Eating Disorders Genetics Initiative 2 (EDGI2): study protocolBerthold, Natasha, MacDermod, Casey M., Thornton, Laura M., Parker, Richard, Morales, Shantal Anid Cortés, Hog, Liv, Kennedy, Hannah L., Guintivano, Jerry, Sullivan, Patrick F., Crowley, James J., Johnson, Jessica S., Birgegård, Andreas, Fundín, Bengt T., Frans, Emma, Xu, Jiayi, “Ngāti Pūkenga”, Michaela Pettie, Miller, Allison L., Aguilar, Mariana Valdez, Barakat, Sarah, Abdulkadir, Mohamed, White, Jennifer P., Larsen, Janne T., Trujillo, Elsie, Winterman, Bertha, Zhang, Ruyue, Lawson, Rachel, Wonderlich, Stephen, Wonderlich, Joseph, Schaefer, Lauren M. ... Bulik, Cynthia M. (2025). The Eating Disorders Genetics Initiative 2 (EDGI2): study protocol. BMC Psychiatry, 25 (1) 532, 1. doi: 10.1186/s12888-025-06777-5 |
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2025 Journal Article Caffeine consumption, psychological distress, and insomnia in a cohort of individuals with depressionMcIntosh, Harry A., Borgas, Aleah J., Aouira, Nisreen, Mitchell, Brittany L., Crouse, Jacob J., Medland, Sarah E., Hickie, Ian B., Wray, Naomi R., Martin, Nicholas G., Middeldorp, Christel M. and Byrne, Enda M. (2025). Caffeine consumption, psychological distress, and insomnia in a cohort of individuals with depression. Complex Psychiatry, 11 (1), 37-49. doi: 10.1159/000545393 |
