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2023

Journal Article

Efficacy and safety of gluten peptide-based antigen-specific immunotherapy (Nexvax2) in adults with coeliac disease after bolus exposure to gluten (RESET CeD): an interim analysis of a terminated randomised, double-blind, placebo-controlled phase 2 study

Tye-Din, Jason A, Daveson, A James M, Goel, Gautam, Goldstein, Kaela E, Hand, Holly L, Neff, Kristin M, Popp, Alina, Taavela, Juha, Maki, Markku, Isola, Jorma, Williams, Leslie J, Truitt, Kenneth E, Anderson, Robert P, Adams, Atoya, Andrews, Jane M, Behrend, Clint E, Brown, Gregor J E, Chen Yi Mei, Swee Lin, Coates, Allan G, DiMarino, Anthony J, Ee, Hooi, Elliott, David E, Epstein, Roger M, Feyen, Bryan John, Fogel, Ronald P, Friedenberg, Keith Alan, Gearry, Richard B, Gerdis, Michael S, Goldstein, Michael J ... Wilson, Scott A (2023). Efficacy and safety of gluten peptide-based antigen-specific immunotherapy (Nexvax2) in adults with coeliac disease after bolus exposure to gluten (RESET CeD): an interim analysis of a terminated randomised, double-blind, placebo-controlled phase 2 study. The Lancet Gastroenterology and Hepatology, 8 (5), 446-457. doi: 10.1016/s2468-1253(22)00428-9

Efficacy and safety of gluten peptide-based antigen-specific immunotherapy (Nexvax2) in adults with coeliac disease after bolus exposure to gluten (RESET CeD): an interim analysis of a terminated randomised, double-blind, placebo-controlled phase 2 study

2023

Journal Article

Alterations to the duodenal microbiota are linked to gastric emptying and symptoms in functional dyspepsia

Shanahan, Erin R., Kang, Seungha, Staudacher, Heidi, Shah, Ayesha, Do, Anh, Burns, Grace, Chachay, Veronique S., Koloski, Natasha A., Keely, Simon, Walker, Marjorie M., Talley, Nicholas J., Morrison, Mark and Holtmann, Gerald J. (2023). Alterations to the duodenal microbiota are linked to gastric emptying and symptoms in functional dyspepsia. Gut, 72 (5) 326158, 929-938. doi: 10.1136/gutjnl-2021-326158

Alterations to the duodenal microbiota are linked to gastric emptying and symptoms in functional dyspepsia

2023

Journal Article

Unravelling the controversy with small intestinal bacterial overgrowth

Shah, Ayesha, Ghoshal, Uday C. and Holtmann, Gerald J. (2023). Unravelling the controversy with small intestinal bacterial overgrowth. Current Opinion in Gastroenterology, 39 (3), 211-218. doi: 10.1097/mog.0000000000000928

Unravelling the controversy with small intestinal bacterial overgrowth

2023

Journal Article

Small intestinal bacterial overgrowth complicating gastrointestinal manifestations of systemic sclerosis: a systematic review and meta-analysis

Shah, Ayesha, Pakeerathan, Veenaa, Jones, Michael P., Kashyap, Purna C., Virgo, Kate, Fairlie, Thomas, Morrison, Mark, Ghoshal, Uday C. and Holtmann, Gerald J. (2023). Small intestinal bacterial overgrowth complicating gastrointestinal manifestations of systemic sclerosis: a systematic review and meta-analysis. Journal of Neurogastroenterology and Motility, 29 (2), 132-144. doi: 10.5056/jnm22168

Small intestinal bacterial overgrowth complicating gastrointestinal manifestations of systemic sclerosis: a systematic review and meta-analysis

2023

Journal Article

Evaluation of small intestinal bacterial overgrowth

Ghoshal, Uday C, Ghoshal, Ujjala, Shah, Ayesha and Holtmann, Gerald (2023). Evaluation of small intestinal bacterial overgrowth. Expert Review of Gastroenterology and Hepatology, 17 (5), 461-467. doi: 10.1080/17474124.2023.2207008

Evaluation of small intestinal bacterial overgrowth

2023

Journal Article

Social determinants and participation in fecal occult blood test based colorectal cancer screening: A qualitative systematic review and meta-synthesis

Marinucci, Nicole, Moy, Naomi, Koloski, Natasha, Shah, Ayesha, Austin, Glenn, Russell‐Bennett, Rebekah, McGraw, Jacquie, Dulleck, Uwe and Holtmann, Gerald (2023). Social determinants and participation in fecal occult blood test based colorectal cancer screening: A qualitative systematic review and meta-synthesis. Health Promotion Journal of Australia, 35 (1), 9-36. doi: 10.1002/hpja.732

Social determinants and participation in fecal occult blood test based colorectal cancer screening: A qualitative systematic review and meta-synthesis

2023

Journal Article

Asia‐Pacific Guidelines for Managing Functional Dyspepsia Overlapping with Other Gastrointestinal Symptoms

Gwee, Kok‐Ann, Lee, Yeong Yeh, Suzuki, Hidekazu, Ghoshal, Uday Chand, Holtmann, Gerald, Bai, Tao, Barbara, Giovanni, Chen, Min‐hu, Chua, Andrew Seng Boon, Gibson, Peter R., Hou, Xiaohua, Liu, Jinsong, Nakajima, Atsushi, Pratap, Nitesh, Sachdeva, Sanjeev, Siah, Kewin Tien Ho, Soh, Alex Yu Sen, Sugano, Kentaro, Tack, Jan, Tan, Victoria Ping Yi, Tang, Xudong, Walker, Marjorie, Wu, Deng‐Chyang, Xiao, Ying‐Lian, Zulkifli, Khairil Khuzaini and Toh, Clarissa (2023). Asia‐Pacific Guidelines for Managing Functional Dyspepsia Overlapping with Other Gastrointestinal Symptoms. Journal of Gastroenterology and Hepatology, 38 (2), 197-209. doi: 10.1111/jgh.16046

Asia‐Pacific Guidelines for Managing Functional Dyspepsia Overlapping with Other Gastrointestinal Symptoms

2023

Journal Article

Placebo effects in functional dyspepsia: causes and implications for clinical trials

Jones, Michael P. and Holtmann, Gerald (2023). Placebo effects in functional dyspepsia: causes and implications for clinical trials. Neurogastroenterology and Motility, 35 (2) e14527, 1-6. doi: 10.1111/nmo.14527

Placebo effects in functional dyspepsia: causes and implications for clinical trials

2023

Journal Article

Endoscopic duodenal-jejunal bypass liner treatment for type 2 diabetes and obesity: glycemic and cardiovascular disease risk factor improvements in 1,022 patients treated worldwide

Ryder, Robert E.J., Laubner, Katharina, Benes, Marek, Haluzik, Martin, Munro, Lynne, Frydenberg, Harry, Teare, Julian P., Ruban, Aruchana, Fishman, Sigal, Santo, Erwin, Stengel, Rainer, De Jonge, Charlotte, Greve, Jan W., Cohen, Ricardo V., Aboud, Cristina M., Holtmann, Gerald J., Rich, Graeme, McMaster, Jess J., Battelino, Tadej, Kotnik, Primoz, Byrne, James P., Mason, John C., Bessell, Justin, Bascomb, Jeanine, Kow, Lillian, Collins, Janes, Chisholm, Jacob, Pferschy, Peter N., Sourij, Harald ... Seufert, Jochen (2023). Endoscopic duodenal-jejunal bypass liner treatment for type 2 diabetes and obesity: glycemic and cardiovascular disease risk factor improvements in 1,022 patients treated worldwide. Diabetes Care, 46 (4), e89-e91. doi: 10.2337/dc22-1952

Endoscopic duodenal-jejunal bypass liner treatment for type 2 diabetes and obesity: glycemic and cardiovascular disease risk factor improvements in 1,022 patients treated worldwide

2023

Journal Article

Type 2 and type 17 effector cells are increased in the duodenal mucosa but not peripheral blood of patients with functional dyspepsia

Burns, Grace L., Bruce, Jessica K., Minahan, Kyra, Mathe, Andrea, Fairlie, Thomas, Cameron, Raquel, Naudin, Crystal, Nair, Prema M., Potter, Michael D. E., Irani, Mudar Zand, Bollipo, Steven, Foster, Robert, Gan, Lay T., Shah, Ayesha, Koloski, Natasha A., Foster, Paul S., Horvat, Jay C., Veysey, Martin, Holtmann, Gerald, Powell, Nick, Walker, Marjorie M., Talley, Nicholas J. and Keely, Simon (2023). Type 2 and type 17 effector cells are increased in the duodenal mucosa but not peripheral blood of patients with functional dyspepsia. Frontiers in Immunology, 13 1051632, 1-14. doi: 10.3389/fimmu.2022.1051632

Type 2 and type 17 effector cells are increased in the duodenal mucosa but not peripheral blood of patients with functional dyspepsia

2022

Journal Article

Zhizhu Kuanzhong Capsule in treating patients with functional dyspepsia postprandial distress syndrome: study protocol for a multicenter, randomized, double-blind, placebo-controlled, parallel-group clinical trial

Xiao, Mengli, Zhong, Linda L. D., Lam, Wai Ching, Zhao, Yingpan, Gwee, Kok-Ann, Holtmann, Gerald, Tack, Jan, Suzuki, Hidekazu, Chen, Min-Hu, Xiao, Yinglian, Hou, Xiaohua, Liu, Jinsong, Li, Yang, Tang, Xu-Dong and Lu, Fang (2022). Zhizhu Kuanzhong Capsule in treating patients with functional dyspepsia postprandial distress syndrome: study protocol for a multicenter, randomized, double-blind, placebo-controlled, parallel-group clinical trial. Trials, 23 (1) 454, 1-10. doi: 10.1186/s13063-022-06396-5

Zhizhu Kuanzhong Capsule in treating patients with functional dyspepsia postprandial distress syndrome: study protocol for a multicenter, randomized, double-blind, placebo-controlled, parallel-group clinical trial

2022

Journal Article

Distinctive gut microbiomes of ankylosing spondylitis and inflammatory bowel disease patients suggest differing roles in pathogenesis and correlate with disease activity

Sternes, P. R., Brett, L., Phipps, J., Ciccia, F., Kenna, T., de Guzman, E., Zimmermann, K., Morrison, M., Holtmann, G., Klingberg, E., Mauro, D., McIvor, C., Forsblad-d’Elia, H. and Brown, M. A. (2022). Distinctive gut microbiomes of ankylosing spondylitis and inflammatory bowel disease patients suggest differing roles in pathogenesis and correlate with disease activity. Arthritis Research and Therapy, 24 (1) 163, 1-10. doi: 10.1186/s13075-022-02853-3

Distinctive gut microbiomes of ankylosing spondylitis and inflammatory bowel disease patients suggest differing roles in pathogenesis and correlate with disease activity

2022

Journal Article

Laparoscopic fundoplication versus laparoscopic Roux-en-Y gastric bypass for gastro-oesophageal reflux disease in obese patients: protocol for a randomized clinical trial

Frankel, Adam, Thomson, Iain, Shah, Ayesha, Chen, Chen, Zahir, Syeda Farah, Barbour, Andrew, Holtmann, Gerald and Mark Smithers, B (2022). Laparoscopic fundoplication versus laparoscopic Roux-en-Y gastric bypass for gastro-oesophageal reflux disease in obese patients: protocol for a randomized clinical trial. BJS Open, 6 (6) zrac132. doi: 10.1093/bjsopen/zrac132

Laparoscopic fundoplication versus laparoscopic Roux-en-Y gastric bypass for gastro-oesophageal reflux disease in obese patients: protocol for a randomized clinical trial

2022

Journal Article

Risk-based decision-making related to preprocedural coronavirus disease 2019 testing in the setting of GI endoscopy: management of risks, evidence, and behavioral health economics

Moy, Naomi, Dulleck, Uwe, Shah, Ayesha, Messmann, Helmut, Thrift, Aaron P., Talley, Nicholas J. and Holtmann, Gerald J. (2022). Risk-based decision-making related to preprocedural coronavirus disease 2019 testing in the setting of GI endoscopy: management of risks, evidence, and behavioral health economics. Gastrointestinal Endoscopy, 96 (5), 735-742.e3. doi: 10.1016/j.gie.2022.05.023

Risk-based decision-making related to preprocedural coronavirus disease 2019 testing in the setting of GI endoscopy: management of risks, evidence, and behavioral health economics

2022

Journal Article

The duodenal mucosa associated microbiome, visceral sensory function, immune activation and psychological comorbidities in functional gastrointestinal disorders with and without self-reported non-celiac wheat sensitivity

Shah, Ayesha, Kang, Seungha, Talley, Nicholas J., Do, Anh, Walker, Marjorie M., Shanahan, Erin R., Koloski, Natasha A., Jones, Michael P., Keely, Simon, Morrison, Mark and Holtmann, Gerald J. (2022). The duodenal mucosa associated microbiome, visceral sensory function, immune activation and psychological comorbidities in functional gastrointestinal disorders with and without self-reported non-celiac wheat sensitivity. Gut Microbes, 14 (1) 2132078, 1-21. doi: 10.1080/19490976.2022.2132078

The duodenal mucosa associated microbiome, visceral sensory function, immune activation and psychological comorbidities in functional gastrointestinal disorders with and without self-reported non-celiac wheat sensitivity

2022

Journal Article

Diabetes mellitus is an independent risk factor for a greater frequency of early satiation and diarrhea at one and three years: two prospective longitudinal population‐based studies

Koloski, Natasha A., Jones, Michael, Walker, Marjorie M., Horowitz, Michael, Holtmann, Gerald and Talley, Nicholas J. (2022). Diabetes mellitus is an independent risk factor for a greater frequency of early satiation and diarrhea at one and three years: two prospective longitudinal population‐based studies. Neurogastroenterology and Motility, 35 (1) e14471, 1-11. doi: 10.1111/nmo.14471

Diabetes mellitus is an independent risk factor for a greater frequency of early satiation and diarrhea at one and three years: two prospective longitudinal population‐based studies

2022

Journal Article

How frequent are vancomycin-resistant enterococci in patients with primary sclerosing cholangitis and ulcerative colitis treated with oral vancomycin?

Shah, Ayesha, Pakneeshan, Sahar, Jones, Michael P., Koloski, Natasha, Callaghan, Gavin, Morrison, Mark and Holtmann, Gerald (2022). How frequent are vancomycin-resistant enterococci in patients with primary sclerosing cholangitis and ulcerative colitis treated with oral vancomycin?. Indian Journal of Gastroenterology, 41 (5), 519-524. doi: 10.1007/s12664-022-01286-9

How frequent are vancomycin-resistant enterococci in patients with primary sclerosing cholangitis and ulcerative colitis treated with oral vancomycin?

2022

Journal Article

Asian-Pacific consensus on small intestinal bacterial overgrowth in gastrointestinal disorders: an initiative of the Indian Neurogastroenterology and Motility Association

Ghoshal, Uday C., Sachdeva, Sanjeev, Ghoshal, Ujjala, Misra, Asha, Puri, Amarender Singh, Pratap, Nitesh, Shah, Ayesha, Rahman, M. Masudur, Gwee, Kok Ann, Tan, Victoria P Y, Ahmed, Tahmeed, Lee, Yeong Yeh, Ramakrishna, B. S., Talukdar, Rupjyoti, Rana, S. V., Sinha, Saroj K, Chen, Minhu, Kim, Nayoung and Holtmann, Gerald (2022). Asian-Pacific consensus on small intestinal bacterial overgrowth in gastrointestinal disorders: an initiative of the Indian Neurogastroenterology and Motility Association. Indian Journal of Gastroenterology, 41 (5), 483-507. doi: 10.1007/s12664-022-01292-x

Asian-Pacific consensus on small intestinal bacterial overgrowth in gastrointestinal disorders: an initiative of the Indian Neurogastroenterology and Motility Association

2022

Journal Article

Links between celiac disease and small intestinal bacterial overgrowth: A systematic review and meta‐analysis

Shah, Ayesha, Thite, Parag, Hansen, Teressa, Kendall, Bradley J., Sanders, David S., Morrison, Mark, Jones, Michael P. and Holtmann, Gerald (2022). Links between celiac disease and small intestinal bacterial overgrowth: A systematic review and meta‐analysis. Journal of Gastroenterology and Hepatology, 37 (10), 1844-1852. doi: 10.1111/jgh.15920

Links between celiac disease and small intestinal bacterial overgrowth: A systematic review and meta‐analysis

2022

Journal Article

Evidence-based and emerging diet recommendations for small bowel disorders

Rej, Anupam, Potter, Michael D. E., Talley, Nicholas J., Shah, Ayesha, Holtmann, Gerald and Sanders, David Surendran (2022). Evidence-based and emerging diet recommendations for small bowel disorders. American Journal of Gastroenterology, 117 (6), 958-964. doi: 10.14309/ajg.0000000000001764

Evidence-based and emerging diet recommendations for small bowel disorders