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2023

Journal Article

Placebo effects in functional dyspepsia: causes and implications for clinical trials

Jones, Michael P. and Holtmann, Gerald (2023). Placebo effects in functional dyspepsia: causes and implications for clinical trials. Neurogastroenterology and Motility, 35 (2) e14527, 1-6. doi: 10.1111/nmo.14527

Placebo effects in functional dyspepsia: causes and implications for clinical trials

2023

Journal Article

Endoscopic duodenal-jejunal bypass liner treatment for type 2 diabetes and obesity: glycemic and cardiovascular disease risk factor improvements in 1,022 patients treated worldwide

Ryder, Robert E.J., Laubner, Katharina, Benes, Marek, Haluzik, Martin, Munro, Lynne, Frydenberg, Harry, Teare, Julian P., Ruban, Aruchana, Fishman, Sigal, Santo, Erwin, Stengel, Rainer, De Jonge, Charlotte, Greve, Jan W., Cohen, Ricardo V., Aboud, Cristina M., Holtmann, Gerald J., Rich, Graeme, McMaster, Jess J., Battelino, Tadej, Kotnik, Primoz, Byrne, James P., Mason, John C., Bessell, Justin, Bascomb, Jeanine, Kow, Lillian, Collins, Janes, Chisholm, Jacob, Pferschy, Peter N., Sourij, Harald ... Seufert, Jochen (2023). Endoscopic duodenal-jejunal bypass liner treatment for type 2 diabetes and obesity: glycemic and cardiovascular disease risk factor improvements in 1,022 patients treated worldwide. Diabetes Care, 46 (4), e89-e91. doi: 10.2337/dc22-1952

Endoscopic duodenal-jejunal bypass liner treatment for type 2 diabetes and obesity: glycemic and cardiovascular disease risk factor improvements in 1,022 patients treated worldwide

2023

Journal Article

Type 2 and type 17 effector cells are increased in the duodenal mucosa but not peripheral blood of patients with functional dyspepsia

Burns, Grace L., Bruce, Jessica K., Minahan, Kyra, Mathe, Andrea, Fairlie, Thomas, Cameron, Raquel, Naudin, Crystal, Nair, Prema M., Potter, Michael D. E., Irani, Mudar Zand, Bollipo, Steven, Foster, Robert, Gan, Lay T., Shah, Ayesha, Koloski, Natasha A., Foster, Paul S., Horvat, Jay C., Veysey, Martin, Holtmann, Gerald, Powell, Nick, Walker, Marjorie M., Talley, Nicholas J. and Keely, Simon (2023). Type 2 and type 17 effector cells are increased in the duodenal mucosa but not peripheral blood of patients with functional dyspepsia. Frontiers in Immunology, 13 1051632, 1-14. doi: 10.3389/fimmu.2022.1051632

Type 2 and type 17 effector cells are increased in the duodenal mucosa but not peripheral blood of patients with functional dyspepsia

2022

Journal Article

Zhizhu Kuanzhong Capsule in treating patients with functional dyspepsia postprandial distress syndrome: study protocol for a multicenter, randomized, double-blind, placebo-controlled, parallel-group clinical trial

Xiao, Mengli, Zhong, Linda L. D., Lam, Wai Ching, Zhao, Yingpan, Gwee, Kok-Ann, Holtmann, Gerald, Tack, Jan, Suzuki, Hidekazu, Chen, Min-Hu, Xiao, Yinglian, Hou, Xiaohua, Liu, Jinsong, Li, Yang, Tang, Xu-Dong and Lu, Fang (2022). Zhizhu Kuanzhong Capsule in treating patients with functional dyspepsia postprandial distress syndrome: study protocol for a multicenter, randomized, double-blind, placebo-controlled, parallel-group clinical trial. Trials, 23 (1) 454, 1-10. doi: 10.1186/s13063-022-06396-5

Zhizhu Kuanzhong Capsule in treating patients with functional dyspepsia postprandial distress syndrome: study protocol for a multicenter, randomized, double-blind, placebo-controlled, parallel-group clinical trial

2022

Journal Article

Distinctive gut microbiomes of ankylosing spondylitis and inflammatory bowel disease patients suggest differing roles in pathogenesis and correlate with disease activity

Sternes, P. R., Brett, L., Phipps, J., Ciccia, F., Kenna, T., de Guzman, E., Zimmermann, K., Morrison, M., Holtmann, G., Klingberg, E., Mauro, D., McIvor, C., Forsblad-d’Elia, H. and Brown, M. A. (2022). Distinctive gut microbiomes of ankylosing spondylitis and inflammatory bowel disease patients suggest differing roles in pathogenesis and correlate with disease activity. Arthritis Research and Therapy, 24 (1) 163, 1-10. doi: 10.1186/s13075-022-02853-3

Distinctive gut microbiomes of ankylosing spondylitis and inflammatory bowel disease patients suggest differing roles in pathogenesis and correlate with disease activity

2022

Journal Article

Laparoscopic fundoplication versus laparoscopic Roux-en-Y gastric bypass for gastro-oesophageal reflux disease in obese patients: protocol for a randomized clinical trial

Frankel, Adam, Thomson, Iain, Shah, Ayesha, Chen, Chen, Zahir, Syeda Farah, Barbour, Andrew, Holtmann, Gerald and Mark Smithers, B (2022). Laparoscopic fundoplication versus laparoscopic Roux-en-Y gastric bypass for gastro-oesophageal reflux disease in obese patients: protocol for a randomized clinical trial. BJS Open, 6 (6) zrac132. doi: 10.1093/bjsopen/zrac132

Laparoscopic fundoplication versus laparoscopic Roux-en-Y gastric bypass for gastro-oesophageal reflux disease in obese patients: protocol for a randomized clinical trial

2022

Journal Article

Risk-based decision-making related to preprocedural coronavirus disease 2019 testing in the setting of GI endoscopy: management of risks, evidence, and behavioral health economics

Moy, Naomi, Dulleck, Uwe, Shah, Ayesha, Messmann, Helmut, Thrift, Aaron P., Talley, Nicholas J. and Holtmann, Gerald J. (2022). Risk-based decision-making related to preprocedural coronavirus disease 2019 testing in the setting of GI endoscopy: management of risks, evidence, and behavioral health economics. Gastrointestinal Endoscopy, 96 (5), 735-742.e3. doi: 10.1016/j.gie.2022.05.023

Risk-based decision-making related to preprocedural coronavirus disease 2019 testing in the setting of GI endoscopy: management of risks, evidence, and behavioral health economics

2022

Journal Article

The duodenal mucosa associated microbiome, visceral sensory function, immune activation and psychological comorbidities in functional gastrointestinal disorders with and without self-reported non-celiac wheat sensitivity

Shah, Ayesha, Kang, Seungha, Talley, Nicholas J., Do, Anh, Walker, Marjorie M., Shanahan, Erin R., Koloski, Natasha A., Jones, Michael P., Keely, Simon, Morrison, Mark and Holtmann, Gerald J. (2022). The duodenal mucosa associated microbiome, visceral sensory function, immune activation and psychological comorbidities in functional gastrointestinal disorders with and without self-reported non-celiac wheat sensitivity. Gut Microbes, 14 (1) 2132078, 1-21. doi: 10.1080/19490976.2022.2132078

The duodenal mucosa associated microbiome, visceral sensory function, immune activation and psychological comorbidities in functional gastrointestinal disorders with and without self-reported non-celiac wheat sensitivity

2022

Journal Article

Diabetes mellitus is an independent risk factor for a greater frequency of early satiation and diarrhea at one and three years: two prospective longitudinal population‐based studies

Koloski, Natasha A., Jones, Michael, Walker, Marjorie M., Horowitz, Michael, Holtmann, Gerald and Talley, Nicholas J. (2022). Diabetes mellitus is an independent risk factor for a greater frequency of early satiation and diarrhea at one and three years: two prospective longitudinal population‐based studies. Neurogastroenterology and Motility, 35 (1) e14471, 1-11. doi: 10.1111/nmo.14471

Diabetes mellitus is an independent risk factor for a greater frequency of early satiation and diarrhea at one and three years: two prospective longitudinal population‐based studies

2022

Journal Article

How frequent are vancomycin-resistant enterococci in patients with primary sclerosing cholangitis and ulcerative colitis treated with oral vancomycin?

Shah, Ayesha, Pakneeshan, Sahar, Jones, Michael P., Koloski, Natasha, Callaghan, Gavin, Morrison, Mark and Holtmann, Gerald (2022). How frequent are vancomycin-resistant enterococci in patients with primary sclerosing cholangitis and ulcerative colitis treated with oral vancomycin?. Indian Journal of Gastroenterology, 41 (5), 519-524. doi: 10.1007/s12664-022-01286-9

How frequent are vancomycin-resistant enterococci in patients with primary sclerosing cholangitis and ulcerative colitis treated with oral vancomycin?

2022

Journal Article

Asian-Pacific consensus on small intestinal bacterial overgrowth in gastrointestinal disorders: an initiative of the Indian Neurogastroenterology and Motility Association

Ghoshal, Uday C., Sachdeva, Sanjeev, Ghoshal, Ujjala, Misra, Asha, Puri, Amarender Singh, Pratap, Nitesh, Shah, Ayesha, Rahman, M. Masudur, Gwee, Kok Ann, Tan, Victoria P Y, Ahmed, Tahmeed, Lee, Yeong Yeh, Ramakrishna, B. S., Talukdar, Rupjyoti, Rana, S. V., Sinha, Saroj K, Chen, Minhu, Kim, Nayoung and Holtmann, Gerald (2022). Asian-Pacific consensus on small intestinal bacterial overgrowth in gastrointestinal disorders: an initiative of the Indian Neurogastroenterology and Motility Association. Indian Journal of Gastroenterology, 41 (5), 483-507. doi: 10.1007/s12664-022-01292-x

Asian-Pacific consensus on small intestinal bacterial overgrowth in gastrointestinal disorders: an initiative of the Indian Neurogastroenterology and Motility Association

2022

Journal Article

Links between celiac disease and small intestinal bacterial overgrowth: A systematic review and meta‐analysis

Shah, Ayesha, Thite, Parag, Hansen, Teressa, Kendall, Bradley J., Sanders, David S., Morrison, Mark, Jones, Michael P. and Holtmann, Gerald (2022). Links between celiac disease and small intestinal bacterial overgrowth: A systematic review and meta‐analysis. Journal of Gastroenterology and Hepatology, 37 (10), 1844-1852. doi: 10.1111/jgh.15920

Links between celiac disease and small intestinal bacterial overgrowth: A systematic review and meta‐analysis

2022

Journal Article

Evidence-based and emerging diet recommendations for small bowel disorders

Rej, Anupam, Potter, Michael D. E., Talley, Nicholas J., Shah, Ayesha, Holtmann, Gerald and Sanders, David Surendran (2022). Evidence-based and emerging diet recommendations for small bowel disorders. American Journal of Gastroenterology, 117 (6), 958-964. doi: 10.14309/ajg.0000000000001764

Evidence-based and emerging diet recommendations for small bowel disorders

2022

Journal Article

Utilising lipid and, arginine and proline metabolism in blood plasma to differentiate the biochemical expression in functional dyspepsia (FD) and irritable bowel syndrome (IBS)

Karpe, Avinash V., Liu, Jian-Wei, Shah, Ayesha, Koloski, Natasha, Holtmann, Gerald and Beale, David J. (2022). Utilising lipid and, arginine and proline metabolism in blood plasma to differentiate the biochemical expression in functional dyspepsia (FD) and irritable bowel syndrome (IBS). Metabolomics, 18 (6) 38, 1-11. doi: 10.1007/s11306-022-01900-z

Utilising lipid and, arginine and proline metabolism in blood plasma to differentiate the biochemical expression in functional dyspepsia (FD) and irritable bowel syndrome (IBS)

2022

Journal Article

Current and future approaches for diagnosing small intestinal dysbiosis in patients with symptoms of functional dyspepsia

Shah, Ayesha, Talley, Nicholas J. and Holtmann, Gerald (2022). Current and future approaches for diagnosing small intestinal dysbiosis in patients with symptoms of functional dyspepsia. Frontiers in Neuroscience, 16 830356, 1-12. doi: 10.3389/fnins.2022.830356

Current and future approaches for diagnosing small intestinal dysbiosis in patients with symptoms of functional dyspepsia

2022

Journal Article

Letter: non‐invasive transabdominal stimulation device for the treatment of chronic constipation—proof‐of‐principle study in adults

Talley, Nicholas J., Holtmann, Gerald J., Southwell, Bridget R., Fisher, David, Koloski, Natasha A. and Jones, Michael (2022). Letter: non‐invasive transabdominal stimulation device for the treatment of chronic constipation—proof‐of‐principle study in adults. Alimentary Pharmacology and Therapeutics, 55 (10), 1354-1356. doi: 10.1111/apt.16877

Letter: non‐invasive transabdominal stimulation device for the treatment of chronic constipation—proof‐of‐principle study in adults

2022

Journal Article

Role of the duodenal microbiota in functional dyspepsia

Brown, Georgia, Hoedt, Emily C., Keely, Simon, Shah, Ayesha, Walker, Marjorie M., Holtmann, Gerald and Talley, Nicholas J. (2022). Role of the duodenal microbiota in functional dyspepsia. Neurogastroenterology and Motility, 34 (11) e14372, e14372. doi: 10.1111/nmo.14372

Role of the duodenal microbiota in functional dyspepsia

2022

Journal Article

Evaluation of a multidisciplinary integrated treatment approach versus standard model of care for Functional Gastrointestinal Disorders (FGIDS): a matched cohort study

Bray, Nicola A., Koloski, Natasha A., Jones, Michael P., Do, Anh, Pang, Siong, Coombes, Jeff S., McAllister, Sarah, Campos, Jane, Arthur, Leela, Stanley, Paul, DeMaria, Katherine, Chao, Che-yung, Catague, Rachel, Whaley, Amanda, Talley, Nicholas J. and Holtmann, Gerald J. (2022). Evaluation of a multidisciplinary integrated treatment approach versus standard model of care for Functional Gastrointestinal Disorders (FGIDS): a matched cohort study. Digestive Diseases and Sciences, 67 (12), 1-9. doi: 10.1007/s10620-022-07464-1

Evaluation of a multidisciplinary integrated treatment approach versus standard model of care for Functional Gastrointestinal Disorders (FGIDS): a matched cohort study

2022

Journal Article

Overlap of heartburn, functional dyspepsia, and irritable bowel syndrome in a population sample: prevalence, temporal stability, and associated comorbidities

Jones, Michael P., Shah, Ayesha, Walker, Marjorie M., Koloski, Natasha A., Holtmann, Gerald and Talley, Nicholas J. (2022). Overlap of heartburn, functional dyspepsia, and irritable bowel syndrome in a population sample: prevalence, temporal stability, and associated comorbidities. Neurogastroenterology and Motility, 34 (9) e14349, e14349. doi: 10.1111/nmo.14349

Overlap of heartburn, functional dyspepsia, and irritable bowel syndrome in a population sample: prevalence, temporal stability, and associated comorbidities

2022

Journal Article

Defects in NLRP6, autophagy and goblet cell homeostasis are associated with reduced duodenal CRH receptor 2 expression in patients with functional dyspepsia

Bruce, Jessica K., Burns, Grace L., Sinn Soh, Wai, Nair, Prema M., Sherwin, Simonne, Fan, KeNing, Dowling, Laura R., Goggins, Bridie J., Koloski, Natasha, Potter, Michael, Bollipo, Steven, Foster, Robert, Gan, Lay T., Veysey, Martin, Philpott, Dana J., Girardin, Stephen E., Holtmann, Gerald, Kaiko, Gerard E., Walker, Marjorie M., Talley, Nicholas J. and Keely, Simon (2022). Defects in NLRP6, autophagy and goblet cell homeostasis are associated with reduced duodenal CRH receptor 2 expression in patients with functional dyspepsia. Brain, Behavior, and Immunity, 101, 335-345. doi: 10.1016/j.bbi.2022.01.019

Defects in NLRP6, autophagy and goblet cell homeostasis are associated with reduced duodenal CRH receptor 2 expression in patients with functional dyspepsia