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2022

Journal Article

Utilising lipid and, arginine and proline metabolism in blood plasma to differentiate the biochemical expression in functional dyspepsia (FD) and irritable bowel syndrome (IBS)

Karpe, Avinash V., Liu, Jian-Wei, Shah, Ayesha, Koloski, Natasha, Holtmann, Gerald and Beale, David J. (2022). Utilising lipid and, arginine and proline metabolism in blood plasma to differentiate the biochemical expression in functional dyspepsia (FD) and irritable bowel syndrome (IBS). Metabolomics, 18 (6) 38, 1-11. doi: 10.1007/s11306-022-01900-z

Utilising lipid and, arginine and proline metabolism in blood plasma to differentiate the biochemical expression in functional dyspepsia (FD) and irritable bowel syndrome (IBS)

2022

Journal Article

Current and future approaches for diagnosing small intestinal dysbiosis in patients with symptoms of functional dyspepsia

Shah, Ayesha, Talley, Nicholas J. and Holtmann, Gerald (2022). Current and future approaches for diagnosing small intestinal dysbiosis in patients with symptoms of functional dyspepsia. Frontiers in Neuroscience, 16 830356, 1-12. doi: 10.3389/fnins.2022.830356

Current and future approaches for diagnosing small intestinal dysbiosis in patients with symptoms of functional dyspepsia

2022

Journal Article

Letter: non‐invasive transabdominal stimulation device for the treatment of chronic constipation—proof‐of‐principle study in adults

Talley, Nicholas J., Holtmann, Gerald J., Southwell, Bridget R., Fisher, David, Koloski, Natasha A. and Jones, Michael (2022). Letter: non‐invasive transabdominal stimulation device for the treatment of chronic constipation—proof‐of‐principle study in adults. Alimentary Pharmacology and Therapeutics, 55 (10), 1354-1356. doi: 10.1111/apt.16877

Letter: non‐invasive transabdominal stimulation device for the treatment of chronic constipation—proof‐of‐principle study in adults

2022

Journal Article

Role of the duodenal microbiota in functional dyspepsia

Brown, Georgia, Hoedt, Emily C., Keely, Simon, Shah, Ayesha, Walker, Marjorie M., Holtmann, Gerald and Talley, Nicholas J. (2022). Role of the duodenal microbiota in functional dyspepsia. Neurogastroenterology and Motility, 34 (11) e14372, e14372. doi: 10.1111/nmo.14372

Role of the duodenal microbiota in functional dyspepsia

2022

Journal Article

Evaluation of a multidisciplinary integrated treatment approach versus standard model of care for Functional Gastrointestinal Disorders (FGIDS): a matched cohort study

Bray, Nicola A., Koloski, Natasha A., Jones, Michael P., Do, Anh, Pang, Siong, Coombes, Jeff S., McAllister, Sarah, Campos, Jane, Arthur, Leela, Stanley, Paul, DeMaria, Katherine, Chao, Che-yung, Catague, Rachel, Whaley, Amanda, Talley, Nicholas J. and Holtmann, Gerald J. (2022). Evaluation of a multidisciplinary integrated treatment approach versus standard model of care for Functional Gastrointestinal Disorders (FGIDS): a matched cohort study. Digestive Diseases and Sciences, 67 (12), 1-9. doi: 10.1007/s10620-022-07464-1

Evaluation of a multidisciplinary integrated treatment approach versus standard model of care for Functional Gastrointestinal Disorders (FGIDS): a matched cohort study

2022

Journal Article

Overlap of heartburn, functional dyspepsia, and irritable bowel syndrome in a population sample: prevalence, temporal stability, and associated comorbidities

Jones, Michael P., Shah, Ayesha, Walker, Marjorie M., Koloski, Natasha A., Holtmann, Gerald and Talley, Nicholas J. (2022). Overlap of heartburn, functional dyspepsia, and irritable bowel syndrome in a population sample: prevalence, temporal stability, and associated comorbidities. Neurogastroenterology and Motility, 34 (9) e14349, e14349. doi: 10.1111/nmo.14349

Overlap of heartburn, functional dyspepsia, and irritable bowel syndrome in a population sample: prevalence, temporal stability, and associated comorbidities

2022

Journal Article

Defects in NLRP6, autophagy and goblet cell homeostasis are associated with reduced duodenal CRH receptor 2 expression in patients with functional dyspepsia

Bruce, Jessica K., Burns, Grace L., Sinn Soh, Wai, Nair, Prema M., Sherwin, Simonne, Fan, KeNing, Dowling, Laura R., Goggins, Bridie J., Koloski, Natasha, Potter, Michael, Bollipo, Steven, Foster, Robert, Gan, Lay T., Veysey, Martin, Philpott, Dana J., Girardin, Stephen E., Holtmann, Gerald, Kaiko, Gerard E., Walker, Marjorie M., Talley, Nicholas J. and Keely, Simon (2022). Defects in NLRP6, autophagy and goblet cell homeostasis are associated with reduced duodenal CRH receptor 2 expression in patients with functional dyspepsia. Brain, Behavior, and Immunity, 101, 335-345. doi: 10.1016/j.bbi.2022.01.019

Defects in NLRP6, autophagy and goblet cell homeostasis are associated with reduced duodenal CRH receptor 2 expression in patients with functional dyspepsia

2022

Journal Article

Etrolizumab as induction and maintenance therapy for ulcerative colitis in patients previously treated with tumour necrosis factor inhibitors (HICKORY): a phase 3, randomised, controlled trial

Peyrin-Biroulet, Laurent, Hart, Ailsa, Bossuyt, Peter, Long, Millie, Allez, Matthieu, Juillerat, Pascal, Armuzzi, Alessandro, Loftus, Edward V, Ostad-Saffari, Elham, Scalori, Astrid, Oh, Young S, Tole, Swati, Chai, Akiko, Pulley, Jennifer, Lacey, Stuart, Sandborn, William J, Aguilar, Humberto, Ahmad, Tariq, Akriviadis, Evangelos, Aldeguer Mante, Xavier, Altorjay, Istvan, Ananthakrishnan, Ashwin, Andersen, Vibeke, Andreu Garcia, Montserrat, Aumais, Guy, Avni-Biron, Irit, Axler, Jeffrey, Ayub, Kamran, Baert, Filip ... Zeuzem, Stefan (2022). Etrolizumab as induction and maintenance therapy for ulcerative colitis in patients previously treated with tumour necrosis factor inhibitors (HICKORY): a phase 3, randomised, controlled trial. The Lancet Gastroenterology and Hepatology, 7 (2), 128-140. doi: 10.1016/S2468-1253(21)00298-3

Etrolizumab as induction and maintenance therapy for ulcerative colitis in patients previously treated with tumour necrosis factor inhibitors (HICKORY): a phase 3, randomised, controlled trial

2022

Journal Article

Duodenal eosinophils and mast cells in functional dyspepsia: a systematic review and meta-analysis of case-control studies

Shah, Ayesha, Fairlie, Thomas, Brown, Georgia, Jones, Michael P., Eslick, Guy D., Duncanson, Kerith, Thapar, Nikhil, Keely, Simon, Koloski, Natasha, Shahi, Mohit, Walker, Marjorie M., Talley, Nicholas J. and Holtmann, Gerald (2022). Duodenal eosinophils and mast cells in functional dyspepsia: a systematic review and meta-analysis of case-control studies. Clinical Gastroenterology and Hepatology, 20 (10), 2229-2242.e29. doi: 10.1016/j.cgh.2022.01.014

Duodenal eosinophils and mast cells in functional dyspepsia: a systematic review and meta-analysis of case-control studies

2022

Journal Article

Updated S3 guideline on intestinal motility disorders: Definition, pathophysiology, diagnosis and treatment. Joint guideline of the German Society for Gastroenterology, Digestive and Metabolic Diseases (DGVS) and the German Society for Neurogastroenterology and Motility (DGNM). June 2021 - AWMF Register No.: 021-018 Update S3-Leitlinie Intestinale Motilitätsstörungen: Definition, Pathophysiologie, Diagnostik und Therapie. Gemeinsame Leitlinie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für Neurogastroenterologie und Motilität (DGNM)

Keller, Jutta, Wedel, Thilo, Seidl, Holger, Kreis, Martin E., Van Der Voort, Ivo, Gebhard, Maximilian, Langhorst, Jost, Lynen Jansen, Petra, Schwandner, Oliver, Storr, Martin, Van Leeuwen, Pia, Andresen, Viola, Preiβ, Jan C., Layer, Peter, Allescher, H., Andus, T., Bischoff, S. C., Buderus, S., Claβen, M., Ehlert, U., Elsenbruch, S., Engel, M., Enninger, A., Fischbach, W., Freitag, M., Frieling, T., Gillessen, A., Goebel-Stengel, M., Gschossmann, J. ... Von Schönfeld, J. (2022). Updated S3 guideline on intestinal motility disorders: Definition, pathophysiology, diagnosis and treatment. Joint guideline of the German Society for Gastroenterology, Digestive and Metabolic Diseases (DGVS) and the German Society for Neurogastroenterology and Motility (DGNM). June 2021 - AWMF Register No.: 021-018 Update S3-Leitlinie Intestinale Motilitätsstörungen: Definition, Pathophysiologie, Diagnostik und Therapie. Gemeinsame Leitlinie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für Neurogastroenterologie und Motilität (DGNM). Zeitschrift fur Gastroenterologie, 60 (2), 192-218. doi: 10.1055/a-1646-1279

Updated S3 guideline on intestinal motility disorders: Definition, pathophysiology, diagnosis and treatment. Joint guideline of the German Society for Gastroenterology, Digestive and Metabolic Diseases (DGVS) and the German Society for Neurogastroenterology and Motility (DGNM). June 2021 - AWMF Register No.: 021-018 Update S3-Leitlinie Intestinale Motilitätsstörungen: Definition, Pathophysiologie, Diagnostik und Therapie. Gemeinsame Leitlinie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für Neurogastroenterologie und Motilität (DGNM)

2022

Journal Article

Small intestinal bacterial overgrowth in inflammatory bowel disease

Shah, Ayesha and Holtmann, Gerald (2022). Small intestinal bacterial overgrowth in inflammatory bowel disease. Indian Journal of Gastroenterology, 41 (1), 23-29. doi: 10.1007/s12664-021-01235-y

Small intestinal bacterial overgrowth in inflammatory bowel disease

2022

Journal Article

Etrolizumab versus adalimumab or placebo as induction therapy for moderately to severely active ulcerative colitis (HIBISCUS): two phase 3 randomised, controlled trials

Rubin, David T, Dotan, Iris, DuVall, Aaron, Bouhnik, Yoram, Radford-Smith, Graham, Higgins, Peter D R, Mishkin, Daniel S, Arrisi, Pablo, Scalori, Astrid, Oh, Young S, Tole, Swati, Chai, Akiko, Chamberlain-James, Kirsten, Lacey, Stuart, McBride, Jacqueline, Panés, Julian, Abdulkhakov, Rustem, Abu Bakar, Norasiah, Aguilar, Humberto, Aizenberg, Diego, Akpinar, Hale, Akriviadis, Evangelos, Alexeeva, Olga, Alikhanov, Bagdadi, Alvarisqueta, Andres, Ananthakrishnan, Ashwin, Andrews, Jane, Arlukowicz, Tomasz, Atkinson, Nathan ... on behalf of the HIBISCUS Study Group (2022). Etrolizumab versus adalimumab or placebo as induction therapy for moderately to severely active ulcerative colitis (HIBISCUS): two phase 3 randomised, controlled trials. The Lancet Gastroenterology and Hepatology, 7 (1), 17-27. doi: 10.1016/S2468-1253(21)00338-1

Etrolizumab versus adalimumab or placebo as induction therapy for moderately to severely active ulcerative colitis (HIBISCUS): two phase 3 randomised, controlled trials

2021

Journal Article

The role of mood state and emotion regulation in the discrepancy between gastrointestinal symptom burden recorded prospectively and via recall questionnaire

Jones, Michael P., Yun, Grace, Wass, Fiona, Rixon, Hayley, Shah, Ayesha, Walker, Marjorie M., Koloski, Natasha A., Holtmann, Gerald, Talley, Nicholas J. and Beath, Alissa P. (2021). The role of mood state and emotion regulation in the discrepancy between gastrointestinal symptom burden recorded prospectively and via recall questionnaire. Neurogastroenterology and Motility, 34 (7) e14304, 1-8. doi: 10.1111/nmo.14304

The role of mood state and emotion regulation in the discrepancy between gastrointestinal symptom burden recorded prospectively and via recall questionnaire

2021

Journal Article

Electroencephalographic evidence of unconscious and conscious attentional bias in people with functional gastrointestinal disorders: A pilot study

Ejova, Anastasia, Badcock, Nicholas A., McKerchar, Sarah, Beath, Alissa P., Swift, Claire, Talley, Nicholas J., Holtmann, Gerald, Walker, Marjorie M. and Jones, Michael P. (2021). Electroencephalographic evidence of unconscious and conscious attentional bias in people with functional gastrointestinal disorders: A pilot study. International Journal of Psychophysiology, 170, 30-42. doi: 10.1016/j.ijpsycho.2021.09.006

Electroencephalographic evidence of unconscious and conscious attentional bias in people with functional gastrointestinal disorders: A pilot study

2021

Journal Article

S3 guideline update on irritable bowel syndrome: Definition, pathophysiology, diagnosis and treatment. Joint guidelines of the German Society for Gastroenterology, Digestive and Metabolic Diseases (DGVS) and the German Society for Neurogastroenterology and Motility (DGNM). June 2021 - AWMF Register No.: 021/016 Update S3-leitlinie reizdarmsyndrom: Definition, pathophysiologie, diagnostik und therapie. Gemeinsame Leitlinie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für neurogastroenterologie und Motilität (DGNM) Juni 2021 - AWMF-registriernummer: 021/016

Layer, Peter, Andresen, Viola, Allescher, H., Bischoff, S. C., Claßen, M., Elsenbruch, S., Freitag, M., Frieling, T., Gebhard, M., Goebel-Stengel, M., Häuser, W., Holtmann, G., Keller, J., Kreis, M. E., Kruis, W., Langhorst, J., Jansen, P. Lynen, Madisch, A., Mönnikes, H., Müller-Lissner, S., Niesler, B., Pehl, C., Pohl, D., Raithel, M., Röhrig-Herzog, G., Schemann, M., Schmiedel, S., Schwille-Kiuntke, J., Storr, M. ... Wedel, T. (2021). S3 guideline update on irritable bowel syndrome: Definition, pathophysiology, diagnosis and treatment. Joint guidelines of the German Society for Gastroenterology, Digestive and Metabolic Diseases (DGVS) and the German Society for Neurogastroenterology and Motility (DGNM). June 2021 - AWMF Register No.: 021/016 Update S3-leitlinie reizdarmsyndrom: Definition, pathophysiologie, diagnostik und therapie. Gemeinsame Leitlinie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für neurogastroenterologie und Motilität (DGNM) Juni 2021 - AWMF-registriernummer: 021/016. Zeitschrift fur Gastroenterologie, 59 (12), 1323-1415. doi: 10.1055/a-1591-4794

S3 guideline update on irritable bowel syndrome: Definition, pathophysiology, diagnosis and treatment. Joint guidelines of the German Society for Gastroenterology, Digestive and Metabolic Diseases (DGVS) and the German Society for Neurogastroenterology and Motility (DGNM). June 2021 - AWMF Register No.: 021/016 Update S3-leitlinie reizdarmsyndrom: Definition, pathophysiologie, diagnostik und therapie. Gemeinsame Leitlinie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für neurogastroenterologie und Motilität (DGNM) Juni 2021 - AWMF-registriernummer: 021/016

2021

Journal Article

Clusters of community-dwelling individuals empirically derived from stool diaries correspond with clinically meaningful outcomes

Jones, Michael P., Walter, Susanna, Talley, Nicholas J., Walker, Marjorie M., Holtmann, Gerald J., Shah, Ayesha, D'Amato, Mauro, Agréus, Lars and Andreasson, Anna (2021). Clusters of community-dwelling individuals empirically derived from stool diaries correspond with clinically meaningful outcomes. European Journal of Gastroenterology and Hepatology, 33 (S1), e740-e745. doi: 10.1097/MEG.0000000000002236

Clusters of community-dwelling individuals empirically derived from stool diaries correspond with clinically meaningful outcomes

2021

Journal Article

Autism-related dietary preferences mediate autism-gut microbiome associations

Yap, Chloe X., Henders, Anjali K., Alvares, Gail A., Wood, David L.A., Krause, Lutz, Tyson, Gene W., Restuadi, Restuadi, Wallace, Leanne, McLaren, Tiana, Hansell, Narelle K., Cleary, Dominique, Grove, Rachel, Hafekost, Claire, Harun, Alexis, Holdsworth, Helen, Jellett, Rachel, Khan, Feroza, Lawson, Lauren P., Leslie, Jodie, Frenk, Mira Levis, Masi, Anne, Mathew, Nisha E., Muniandy, Melanie, Nothard, Michaela, Miller, Jessica L., Nunn, Lorelle, Holtmann, Gerald, Strike, Lachlan T., de Zubicaray, Greig I. ... Gratten, Jacob (2021). Autism-related dietary preferences mediate autism-gut microbiome associations. Cell, 184 (24), 5916-5931.e17. doi: 10.1016/j.cell.2021.10.015

Autism-related dietary preferences mediate autism-gut microbiome associations

2021

Journal Article

Antibiotic use but not gastrointestinal infection frequently precedes first diagnosis of functional gastrointestinal disorders

Jones, Michael P., Shah, Ayesha, Walker, Marjorie M., Koloski, Natasha A., Holtmann, Gerald and Talley, Nicholas J. (2021). Antibiotic use but not gastrointestinal infection frequently precedes first diagnosis of functional gastrointestinal disorders. United European Gastroenterology Journal, 9 (9), 1074-1080. doi: 10.1002/ueg2.12164

Antibiotic use but not gastrointestinal infection frequently precedes first diagnosis of functional gastrointestinal disorders

2021

Journal Article

Physician perceptions on the use of antibiotics and probiotics in adults: an international survey in the Asia-Pacific area

Ghoshal, Uday C., Gwee, Kok-Ann, Holtmann, Gerald, Li, Yanmei, Park, Soo Jung, Simadibrata, Marcellus, Sugano, Kentaro, Cohen, Henry and Quigley, Eamonn M. M. (2021). Physician perceptions on the use of antibiotics and probiotics in adults: an international survey in the Asia-Pacific area. Frontiers in Cellular and Infection Microbiology, 11 722700, 722700. doi: 10.3389/fcimb.2021.722700

Physician perceptions on the use of antibiotics and probiotics in adults: an international survey in the Asia-Pacific area

2021

Journal Article

Draft genome sequence of streptococcus salivarius AGIRA0003, isolated from functional gastrointestinal disorder duodenal tissue

Hoedt, Emily C., Shanahan, Erin R., Keely, Simon, Shah, Ayesha, Burns, Grace L., Holtmann, Gerald J., Talley, Nicholas J. and Morrison, Mark (2021). Draft genome sequence of streptococcus salivarius AGIRA0003, isolated from functional gastrointestinal disorder duodenal tissue. Microbiology Resource Announcements, 10 (39) e00758, e0075821. doi: 10.1128/MRA.00758-21

Draft genome sequence of streptococcus salivarius AGIRA0003, isolated from functional gastrointestinal disorder duodenal tissue