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2023

Conference Publication

Acetohydroxyacid synthase: structure, function, regulation and inhibition

Guddat, Luke W. (2023). Acetohydroxyacid synthase: structure, function, regulation and inhibition. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323095050

Acetohydroxyacid synthase: structure, function, regulation and inhibition

2023

Conference Publication

Structural basis of resistance to herbicides that target acetohydroxyacid synthase

Cheng, Yan, Lonhienne, Thierry, Garcia, Mario, Hu, Shu Hong, Low, Yu Shang, Schenk, Gerhard, Williams, Craig M. and Guddat, Luke W. (2023). Structural basis of resistance to herbicides that target acetohydroxyacid synthase. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323085571

Structural basis of resistance to herbicides that target acetohydroxyacid synthase

2023

Conference Publication

Investigations of Mycobacterium tuberculosis acetohydroxyacid synthases as therapeutic drug targets

Gao, Yanhua, Wu, Shunjie, Lonhienne, Thierry, Lin, Xin and Guddat, Luke (2023). Investigations of Mycobacterium tuberculosis acetohydroxyacid synthases as therapeutic drug targets. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323085583

Investigations of Mycobacterium tuberculosis acetohydroxyacid synthases as therapeutic drug targets

2023

Conference Publication

Structural investigation of two commercial herbicides that target acetohydroxyacid synthase

Zhao, Qi, Cheng, Yan, Lonhienne, Thierry and Guddat, Luke W. (2023). Structural investigation of two commercial herbicides that target acetohydroxyacid synthase. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s205327332308556x

Structural investigation of two commercial herbicides that target acetohydroxyacid synthase

2023

Conference Publication

Targeting acetohydroxyacid synthase to discover new therapeutics for Cryptococcus neoformans infections

Ge, Xiaoling, Lonhienne, Thierry, Garcia, Mario D. and Guddat, Luke W. (2023). Targeting acetohydroxyacid synthase to discover new therapeutics for Cryptococcus neoformans infections. XXVI IUCr Congress, Melbourne, VIC Australia, 22-29 August 2023. Hoboken, NJ United States: Wiley-Blackwell. doi: 10.1107/s2053273323085546

Targeting acetohydroxyacid synthase to discover new therapeutics for Cryptococcus neoformans infections

2017

Conference Publication

Ketol-acid-reductoisomerase, an emerging target for herbicides and novel antimicrobial agents

Schenk, Gerhard and Guddat, Luke W. (2017). Ketol-acid-reductoisomerase, an emerging target for herbicides and novel antimicrobial agents. 18th International Conference on Biological Inorganic Chemistry (ICBIC), Florianopolis Brazil, 31 July - 4 August 2017. New York, NY United States: Springer.

Ketol-acid-reductoisomerase, an emerging target for herbicides and novel antimicrobial agents

2006

Conference Publication

Inhibition studies of purple acid phosphatases: Implications for the catalytic mechanism

Elliott, Tristan W., Mitić, Nataša, Gahan, Lawrence R., Guddat, Luke W. and Schenk, Gerhard (2006). Inhibition studies of purple acid phosphatases: Implications for the catalytic mechanism. Sociedade Brasileira de Quimica. doi: 10.1590/S0103-50532006000800011

Inhibition studies of purple acid phosphatases: Implications for the catalytic mechanism

2005

Conference Publication

Overlapping sulfonylurea and imidazolinone herbicide binding sites in Arabidopsis thaliana acetohydroxyacid synthase

McCourt, J. A., Pang, S. S., King-Scott, J., Guddat, L. W. and Duggleby, R.G. (2005). Overlapping sulfonylurea and imidazolinone herbicide binding sites in Arabidopsis thaliana acetohydroxyacid synthase. East Coast Protein Meeting, Coffs Harbour, 24-26 June, 2005.

Overlapping sulfonylurea and imidazolinone herbicide binding sites in Arabidopsis thaliana acetohydroxyacid synthase

2005

Conference Publication

3D structure of the overlapping sulfonylurea and imidazolinone herbicide binding sites in acetohydroxyacid synthase

Duggleby, R.G., McCourt, J. A. and Guddat, L. W. (2005). 3D structure of the overlapping sulfonylurea and imidazolinone herbicide binding sites in acetohydroxyacid synthase. 9th Int Congress on Amino Acids & Proteins, Vienna, 8-12 Aug, 2005.

3D structure of the overlapping sulfonylurea and imidazolinone herbicide binding sites in acetohydroxyacid synthase

2005

Conference Publication

Crystal structure of Escherichia coli ketol-acid reductoisomerase

Duggleby, R.G., Tyagi, R., Duquerroy, S., Navaza, J. and Guddat, L. W. (2005). Crystal structure of Escherichia coli ketol-acid reductoisomerase. East Coast Protein Meeting, Coffs Harbour, 24-26 June, 2005.

Crystal structure of Escherichia coli ketol-acid reductoisomerase

2005

Conference Publication

Elucidation of the binding site for five sulfonylurea herbicides in Arabidopsis thaliana

McCourt, J. A., Pang, S. S., King-Scott, J., Guddat, L. W. and Duggleby, R.G. (2005). Elucidation of the binding site for five sulfonylurea herbicides in Arabidopsis thaliana. 30th Annual Lorne Conference on Protein Structure and Function, Lorne, 6-11 Feb, 2005.

Elucidation of the binding site for five sulfonylurea herbicides in Arabidopsis thaliana

2005

Conference Publication

Crystal structure of textilinin-1

Millers, E. I., Masci, P., Lavin, M. F., De Jersey, J. and Guddat, L. W. (2005). Crystal structure of textilinin-1. East Coast Protein Meeting, Coffs Harbour, 24-26 June, 2005.

Crystal structure of textilinin-1

2003

Conference Publication

The crystal structures of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate

Duggleby, R.G., Pang, S. S., Schowen, R. L. and Guddat, L. W. (2003). The crystal structures of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate. East Coast Protein Meeting, Coffs Harbour, 27-29 June, 2003.

The crystal structures of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate

2003

Conference Publication

Crystal structure and mechanism of a purple acid phosphatase from sweet potato: an enzyme with a novel Fe-Mn binuclear metal centre

Schenk, G., Carrington, L., Valizadeh, M., De Jersey, J., Hamilton, S. E. and Guddat, L.W. (2003). Crystal structure and mechanism of a purple acid phosphatase from sweet potato: an enzyme with a novel Fe-Mn binuclear metal centre. International Conference on Biological Inorganic Chemistry, Cairns, 19-23 July, 2003.

Crystal structure and mechanism of a purple acid phosphatase from sweet potato: an enzyme with a novel Fe-Mn binuclear metal centre

2003

Conference Publication

Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase

Pang, S. S., Guddat, L. W. and Duggleby, R.G. (2003). Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase. East Coast Protein Meeting, Coffs Harbour, 27-29 June, 2003.

Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase

2002

Conference Publication

Yeast acetohydroxyacid synthase. Crystal structure of an enzyme containing non-catalytic FAD

Pang, S. S., Guddat, L. W. and Duggleby, R.G. (2002). Yeast acetohydroxyacid synthase. Crystal structure of an enzyme containing non-catalytic FAD. 14th Int Symposium on Flavins and Flavoproteins, Cambridge, UK, 14-18 July, 2002.

Yeast acetohydroxyacid synthase. Crystal structure of an enzyme containing non-catalytic FAD

2002

Conference Publication

Substrate analogues discriminate between human and Plasmodium falciparum 6-oxopurine phosphoribosyltransferases

Keough, D. T., Dulley, G., Guddat, L. W., Naesens, L. and De Jersey, J. (2002). Substrate analogues discriminate between human and Plasmodium falciparum 6-oxopurine phosphoribosyltransferases. ComBio 2002, Sydney, 29 September - 3 October, 2002.

Substrate analogues discriminate between human and Plasmodium falciparum 6-oxopurine phosphoribosyltransferases

2001

Conference Publication

Structural analysis of the hnRNP A proteins: Understanding the interaction between hnRNP A2 and the A2RE trafficking element

Landsberg, M., Guddat, L. W., Hawkins, B. L. and Smith, R. W. (2001). Structural analysis of the hnRNP A proteins: Understanding the interaction between hnRNP A2 and the A2RE trafficking element. ASBMB, Canberra, 31 Sept-4 Oct, 2001.

Structural analysis of the hnRNP A proteins: Understanding the interaction between hnRNP A2 and the A2RE trafficking element

2000

Conference Publication

Sweet potato purple acid phosphatase: first example of a strongly antiferromagnetically coupled Fe-Mn binuclear centre in a protein

Schenk, G., Boutchard, C., Noble, C. J., Moubaraki, B., Murray, K. S., Hanson, G. R., De Jersey, J., Hamilton, S. E., Guddat, L. W. and Carrington, L. (2000). Sweet potato purple acid phosphatase: first example of a strongly antiferromagnetically coupled Fe-Mn binuclear centre in a protein. EUROBIC-5, Toulouse, France, 17-20 July 2000.

Sweet potato purple acid phosphatase: first example of a strongly antiferromagnetically coupled Fe-Mn binuclear centre in a protein

1999

Conference Publication

Plasmodium Falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase as a chemotherapeutic target: Comparison of the human and parasite enzymes

Dulley, G., Ng, A., Qi, J., Guddat, L. W., Keough, D. T. and De Jersey, J. (1999). Plasmodium Falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase as a chemotherapeutic target: Comparison of the human and parasite enzymes. ComBio 99, Conrad Jupiter, Gold Coast, 27-30 September, 1999. Kent Town, SA: Australian Society for Biochemistry and Molecular Biology.

Plasmodium Falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase as a chemotherapeutic target: Comparison of the human and parasite enzymes