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2021

Journal Article

EBV-associated primary CNS lymphoma occurring after immunosuppression is a distinct immunobiological entity

Gandhi, Maher K., Hoang, Thanh, Law, Soi C., Brosda, Sandra, O'Rourke, Kacey, Tobin, Joshua W. D., Vari, Frank, Murigneux, Valentine, Fink, J. Lynn, Gunawardana, Jay, Gould, Clare M., Oey, Harald, Bednarska, Karolina, Delecluse, Susanne, Trappe, Ralf Ulrich, de Long, Lilia Merida, Sabdia, Muhammed Bilal, Bhagat, Govind, Hapgood, Greg, Blyth, Emily, Clancy, Leighton E., Wight, Joel, Hawkes, Eliza A., Rimsza, Lisa M., Maguire, Alanna, Bojarczuk, Kamil, Chapuy, Bjoern and Keane, Colm (2021). EBV-associated primary CNS lymphoma occurring after immunosuppression is a distinct immunobiological entity. Blood, 137 (11), 1468-1477. doi: 10.1182/blood.2020008520

EBV-associated primary CNS lymphoma occurring after immunosuppression is a distinct immunobiological entity

2019

Journal Article

EBV-microRNA-BHRF1-2-5p targets the 3'UTR of immune-checkpoint ligands PD-L1 and PD-L2

Cristino, Alexandre S., Nourse, Jamie, West, Rachael A., Sabdia, Muhammed Bilal, Law, Soi C., Gunawardana, Jay, Vari, Frank, Mujaj, Sally, Thillaiyampalam, Gayathri, Snell, Cameron, Gough, Madeline, Keane, Colm and Gandhi, Maher K. (2019). EBV-microRNA-BHRF1-2-5p targets the 3'UTR of immune-checkpoint ligands PD-L1 and PD-L2. Blood, 134 (25), 2261-2270. doi: 10.1182/blood.2019000889

EBV-microRNA-BHRF1-2-5p targets the 3'UTR of immune-checkpoint ligands PD-L1 and PD-L2

2019

Journal Article

Progression of disease within 24 months in follicular lymphoma is associated with reduced intratumoral immune infiltration

Tobin, Joshua W. D., Keane, Colm, Gunawardana, Jay, Mollee, Peter, Birch, Simone, Hoang, Thanh, Lee, Justina, Li, Li, Huang, Li, Murigneux, Valentine, Fink, J. Lynn, Matigian, Nicholas, Vari, Frank, Francis, Santiyagu, Kridel, Robert, Weigert, Oliver, Haebe, Sarah, Jurinovic, Vindi, Klapper, Wolfram, Steidl, Christian, Sehn, Laurie H., Law, Soi-Cheng, Wykes, Michelle N. and Gandhi, Maher K. (2019). Progression of disease within 24 months in follicular lymphoma is associated with reduced intratumoral immune infiltration. Journal of Clinical Oncology, 37 (34), 3300-3309. doi: 10.1200/JCO.18.02365

Progression of disease within 24 months in follicular lymphoma is associated with reduced intratumoral immune infiltration

2018

Journal Article

Immune evasion via PD-1/PD-L1 on NK-cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL

Vari, Frank, Arpon, David, Keane, Colm, Hertzberg, Mark S, Talaulikar, Dipti, Jain, Sanjiv, Cui, Qingyan, Han, Erica, Tobin, Josh, Bird, Robert, Cross, Donna, Hernandez, Annette, Gould, Clare, Birch, Simone and Gandhi, Maher K (2018). Immune evasion via PD-1/PD-L1 on NK-cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL. Blood, 131 (16), 1809-1819. doi: 10.1182/blood-2017-07-796342

Immune evasion via PD-1/PD-L1 on NK-cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL

2017

Journal Article

The T-cell receptor repertoire influences the tumor microenvironment and is associated with survival in aggressive B-cell lymphoma

Keane, Colm, Gould, Clare, Jones, Kimberley, Hamm, David, Talaulikar, Dipti, Ellis, Jonathan, Vari, Frank, Birch, Simone, Han, Erica, Wood, Peter, Le-Cao, Kim-Anh, Green, Michael R., Crooks, Pauline, Jain, Sanjiv, Tobin, Josh, Steptoe, Raymond J. and Gandhi, Maher K. (2017). The T-cell receptor repertoire influences the tumor microenvironment and is associated with survival in aggressive B-cell lymphoma. Clinical Cancer Research, 23 (7), 1820-1828. doi: 10.1158/1078-0432.CCR-16-1576

The T-cell receptor repertoire influences the tumor microenvironment and is associated with survival in aggressive B-cell lymphoma

2024

Journal Article

Intra‐tumoral and peripheral blood <scp>TIGIT</scp> and <scp>PD</scp>‐1 as immune biomarkers in nodular lymphocyte predominant Hodgkin lymphoma

Gunawardana, Jay, Law, Soi C., Sabdia, Muhammed B., Fennell, Éanna, Hennessy, Aoife, Leahy, Ciara I., Murray, Paul G., Bednarska, Karolina, Brosda, Sandra, Trotman, Judith, Berkahn, Leanne, Zaharia, Andreea, Birch, Simone, Burgess, Melinda, Talaulikar, Dipti, Lee, Justina N., Jude, Emily, Hawkes, Eliza A., Jain, Sanjiv, Nath, Karthik, Snell, Cameron, Swain, Fiona, Tobin, Joshua W. D., Keane, Colm, Shanavas, Mohamed, Blyth, Emily, Steidl, Christian, Savage, Kerry, Farinha, Pedro ... Gandhi, Maher K. (2024). Intra‐tumoral and peripheral blood TIGIT and PD‐1 as immune biomarkers in nodular lymphocyte predominant Hodgkin lymphoma. American Journal of Hematology. doi: 10.1002/ajh.27459

Intra‐tumoral and peripheral blood <scp>TIGIT</scp> and <scp>PD</scp>‐1 as immune biomarkers in nodular lymphocyte predominant Hodgkin lymphoma

2024

Journal Article

Identification of genetic subtypes in follicular lymphoma

Shelton, Victoria, Detroja, Rajesh, Liu, Ting, Isaev, Keren, Silva, Anjali, Passerini, Verena, Bakhtiari, Mehran, Calvente, Lourdes, Hong, Michael, He, Michael Y., Modi, Saloni, Hershenfeld, Samantha A., Ludvigsen, Maja, Madsen, Charlotte, Hamilton-Dutoit, Stephen, d’Amore, Francesco Annibale, Brodtkorb, Marianne, Johnson, Nathalie A., Baetz, Tara, LeBrun, David, Tobin, Josh W. D., Gandhi, Maher K., Mungall, Andrew J., Xu, Wei, Ben-Neriah, Susana, Steidl, Christian, Delabie, Jan, Tremblay-LeMay, Rosemarie, Jegede, Opeyemi ... Kridel, Robert (2024). Identification of genetic subtypes in follicular lymphoma. Blood Cancer Journal, 14 (1) 128. doi: 10.1038/s41408-024-01111-w

Identification of genetic subtypes in follicular lymphoma

2024

Journal Article

Systemic diffuse large B-cell lymphoma involving the central nervous system have high rates of defective antigen presentation and immune surveillance

Wight, Joel, Blombery, Piers, Lickiss, Jennifer, Burgess, Melinda, Gould, Clare, Minson, Adrian, Swain, Fiona, Sabdia, Muhammed B., Gandhi, Maher K., Birchley, Andrew, Keane, Colm and Hawkes, Eliza A (2024). Systemic diffuse large B-cell lymphoma involving the central nervous system have high rates of defective antigen presentation and immune surveillance. Haematologica, 109 (9), 3013-3018. doi: 10.3324/haematol.2023.284600

Systemic diffuse large B-cell lymphoma involving the central nervous system have high rates of defective antigen presentation and immune surveillance

2024

Journal Article

EBNA2: a viral maestra conducting a symphony orchestra

Gandhi, Maher K. and Kelly, Gemma L. (2024). EBNA2: a viral maestra conducting a symphony orchestra. Blood, 143 (5), 384-385. doi: 10.1182/blood.2023022744

EBNA2: a viral maestra conducting a symphony orchestra

2024

Journal Article

Epstein–Barr virus‐associated lymphomas decoded

Bednarska, Karolina, Chowdhury, Rakin, Tobin, Joshua W. D., Swain, Fiona, Keane, Colm, Boyle, Stephen, Khanna, Rajiv and Gandhi, Maher K. (2024). Epstein–Barr virus‐associated lymphomas decoded. British Journal of Haematology, 204 (2), 415-433. doi: 10.1111/bjh.19255

Epstein–Barr virus‐associated lymphomas decoded

2024

Journal Article

Harnessing the cytotoxic granule exocytosis to augment the efficacy of T-cell-engaging bispecific antibody therapy

Casey, Mika, Lee, Carol, Hoyte, Sharon M., Johnston, Rebecca L., Kwok, Wing Yu, Law, Soi Cheng, Gandhi, Maher K, Harrison, Simon J and Nakamura, Kyohei (2024). Harnessing the cytotoxic granule exocytosis to augment the efficacy of T-cell-engaging bispecific antibody therapy. Haematologica, 109 (7), 2131-2143. doi: 10.3324/haematol.2023.284435

Harnessing the cytotoxic granule exocytosis to augment the efficacy of T-cell-engaging bispecific antibody therapy

2024

Journal Article

EBV-infected hematopoietic stem cells drive CAEBV

Khanna, Rajiv and Gandhi, Maher K. (2024). EBV-infected hematopoietic stem cells drive CAEBV. Blood, 143 (1), 2-4. doi: 10.1182/blood.2023022739

EBV-infected hematopoietic stem cells drive CAEBV

2024

Journal Article

The IRE1α endonuclease plays a dual role in regulating the XBP1/miRNA-34a axis and PD-1 Expression within natural killer cells in Hodgkin lymphoma

Bednarska, Karolina, Thillaiyampalam, Gayathri, Mujaj, Sally, Nourse, Jamie, Gunawardana, Jay, Sabdia, Muhammed B., Law, Soi C., Pilaar, Anna, Cui, Qingyan, de Long, Lilia M., Vari, Frank, Gandhi, Maher K. and Cristino, Alexandre S. (2024). The IRE1α endonuclease plays a dual role in regulating the XBP1/miRNA-34a axis and PD-1 Expression within natural killer cells in Hodgkin lymphoma. Acta Haematologica, 1-16. doi: 10.1159/000536044

The IRE1α endonuclease plays a dual role in regulating the XBP1/miRNA-34a axis and PD-1 Expression within natural killer cells in Hodgkin lymphoma

2024

Journal Article

Single gene mutations and prognosis in limited-stage follicular lymphoma treated with radiation therapy

Hershenfeld, Samantha A., Tobin, Josuha W.D., Shelton, Victoria, Calvente, Lourdes, Lajkosz, Katherine, Liu, Ting, Brodtkorb, Marianne, d'Amore, Francesco Annibale, Ludvigsen, Maja, Baetz, Tara, LeBrun, David, Johnson, Nathalie, Crump, Michael, Hong, Michael, Kuruvilla, John, Tremblay-LeMay, Rosemarie, MacManus, Michael, Tsang, Richard, Hodgson, David C., Gandhi, Maher K. and Kridel, Robert (2024). Single gene mutations and prognosis in limited-stage follicular lymphoma treated with radiation therapy. British Journal of Haematology. doi: 10.1111/bjh.19698

Single gene mutations and prognosis in limited-stage follicular lymphoma treated with radiation therapy

2023

Journal Article

Genome-wide transcription factor binding maps reveal cell-specific changes in the regulatory architecture of human HSPC

Subramanian, Shruthi, Thoms, Julie A I, Huang, Yizhou, Cornejo Paramo, Carina Paola, Koch, Forrest Charles, Jacquelin, Sebastien, Shen, Sylvie, Song, Emma, Joshi, Swapna, Brownlee, Christopher Peter, Woll, Petter S., Chacon-Fajardo, Diego, Beck, Dominik, Curtis, David J, Yehson, Kenneth, Antonenas, Vicki, O'Brien, Tracey, Trickett, Annette, Powell, Jason A., Lewis, Ian D, Pitson, Stuart M, Gandhi, Maher K., Lane, Steven W, Vafaee, Fatemeh, Wong, Emily, Gottgens, Berthold, Rokny, Hamid, Wong, Jason Wing Hon and Pimanda, John E (2023). Genome-wide transcription factor binding maps reveal cell-specific changes in the regulatory architecture of human HSPC. Blood Journal, 142 (17), 1448-1462. doi: 10.1182/blood.2023021120

Genome-wide transcription factor binding maps reveal cell-specific changes in the regulatory architecture of human HSPC

2023

Journal Article

Regulatory T cells hamper the efficacy of T-cell engaging bispecific antibody therapy

Casey, Mika, Lee, Carol, Kwok, Wing Yu, Law, Soi Cheng, Corvino, Dillon, Gandhi, Maher K., Harrison, Simon J. and Nakamura, Kyohei (2023). Regulatory T cells hamper the efficacy of T-cell engaging bispecific antibody therapy. Haematologica, 109 (3), 787-798. doi: 10.3324/haematol.2023.283758

Regulatory T cells hamper the efficacy of T-cell engaging bispecific antibody therapy

2023

Journal Article

Expanding the bacterial origins of nodular lymphocyte predominant Hodgkin lymphoma

Gandhi, Maher K. and Keane, Colm (2023). Expanding the bacterial origins of nodular lymphocyte predominant Hodgkin lymphoma. Haematologica, 108 (12), 3195-3196. doi: 10.3324/haematol.2023.283392

Expanding the bacterial origins of nodular lymphocyte predominant Hodgkin lymphoma

2023

Journal Article

Resolution of melanoma to PD-1 blockade but simultaneous rapid progression of concomitant chronic lymphocytic leukemia

Burgess, Melinda, Keane, Colm, Tobin, Joshua W. D., Law, Soi Cheng, Griffin, Alison, Gill, Devinder, Ewing, Adam D., Atkinson, Victoria, Mollee, Peter, Sabdia, Muhammed B., Saunders, Nicholas and Gandhi, Maher K. (2023). Resolution of melanoma to PD-1 blockade but simultaneous rapid progression of concomitant chronic lymphocytic leukemia. Acta Haematologica, 146 (2), 166-171. doi: 10.1159/000527631

Resolution of melanoma to PD-1 blockade but simultaneous rapid progression of concomitant chronic lymphocytic leukemia

2023

Journal Article

A coordinated strategy for a simple, pragmatic approach to the early identification of the ultra‐high‐risk patient with diffuse large B‐cell lymphoma

George, Hannah, Gunawardana, Jay, Keane, Colm, Hicks, Rod J. and Gandhi, Maher K. (2023). A coordinated strategy for a simple, pragmatic approach to the early identification of the ultra‐high‐risk patient with diffuse large B‐cell lymphoma. Internal Medicine Journal, 53 (7), 1105-1109. doi: 10.1111/imj.16078

A coordinated strategy for a simple, pragmatic approach to the early identification of the ultra‐high‐risk patient with diffuse large B‐cell lymphoma

2023

Journal Article

Genetic susceptibility to EBV-related disease

Gandhi, Maher K. (2023). Genetic susceptibility to EBV-related disease. Blood, 141 (13), 1499-1500. doi: 10.1182/blood.2022019180

Genetic susceptibility to EBV-related disease