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2009

Journal Article

c-Jun NH2-terminal kinase activity in subcutaneous adipose tissue but not nuclear factor-κB activity in peripheral blood mononuclear cells is an independent determinant of insulin resistance in healthy individuals

Sourris, Karly C., Lyons, Jasmine G., de Courten, Maximilian P. J., Dougherty, Sonia L., Henstridge, Darren C., Cooper, Mark E., Hage, Michelle, Dart, Anthony, Kingwell, Bronwyn A., Forbes, Josephine M. and de Courten, Barbora (2009). c-Jun NH2-terminal kinase activity in subcutaneous adipose tissue but not nuclear factor-κB activity in peripheral blood mononuclear cells is an independent determinant of insulin resistance in healthy individuals. Diabetes, 58 (6), 1259-1265. doi: 10.2337/db08-1725

c-Jun NH2-terminal kinase activity in subcutaneous adipose tissue but not nuclear factor-κB activity in peripheral blood mononuclear cells is an independent determinant of insulin resistance in healthy individuals

2009

Journal Article

High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus

Drew, Brian G., Duffy, Stephen J., Formosa, Melissa F., Natoli, Alaina K., Henstridge, Darren C., Penfold, Sally A., Thomas, Walter G., Mukhamedova, Nigora, de Courten, Barbora, Forbes, Josephine M., Yap, Felicia Y., Kaye, David M., van Hall, Gerrit, Febbraio, Mark A., Kemp, Bruce E., Sviridov, Dmitri, Steinberg, Gregory R. and Kingwell, Bronwyn A. (2009). High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus. Circulation, 119 (15), 2103-2111. doi: 10.1161/CIRCULATIONAHA.108.843219

High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus

2009

Journal Article

The effect of salsalate on insulin action and glucose tolerance in obese non-diabetic patients: results of a randomised double-blind placebo-controlled study

Koska, J., Ortega, E., Bunt, J. C., Gasser, A., Impson, J., Hanson, R. L., Forbes, J., de Courten, B. and Krakoff, J. (2009). The effect of salsalate on insulin action and glucose tolerance in obese non-diabetic patients: results of a randomised double-blind placebo-controlled study. Diabetologia, 52 (3), 385-393. doi: 10.1007/s00125-008-1239-x

The effect of salsalate on insulin action and glucose tolerance in obese non-diabetic patients: results of a randomised double-blind placebo-controlled study

2009

Journal Article

Interactions Between Advanced Glycation End-Products (AGE) and their Receptors in the Development and Progression of Diabetic Nephropathy - are these Receptors Valid Therapeutic Targets

Sourris, Karly C. and Forbes, Josephine M. (2009). Interactions Between Advanced Glycation End-Products (AGE) and their Receptors in the Development and Progression of Diabetic Nephropathy - are these Receptors Valid Therapeutic Targets. Current Drug Targets, 10 (1), 42-50. doi: 10.2174/138945009787122905

Interactions Between Advanced Glycation End-Products (AGE) and their Receptors in the Development and Progression of Diabetic Nephropathy - are these Receptors Valid Therapeutic Targets

2009

Journal Article

A new perspective on therapeutic inhibition of advanced glycation in diabetic microvascular complications: Common downstream endpoints achieved through disparate therapeutic approaches?

Sourris, Karly C., Harcourt, Brooke E. and Forbes, Josephine M. (2009). A new perspective on therapeutic inhibition of advanced glycation in diabetic microvascular complications: Common downstream endpoints achieved through disparate therapeutic approaches?. American Journal of Nephrology, 30 (4), 323-335. doi: 10.1159/000226586

A new perspective on therapeutic inhibition of advanced glycation in diabetic microvascular complications: Common downstream endpoints achieved through disparate therapeutic approaches?

2009

Journal Article

Rage-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes

Coughlan, Melinda T., Thorburn, David R., Penfold, Sally A., Laskowski, Adrienne, Harcourt, Brooke E., Sourris, Karly C., Tan, Adeline L. Y., Fukami, Kei, Thallas-Bonke, Vicki, Nawroth, Peter P., Brownlee, Michael, Bierhaus, Angelika, Cooper, Mark E. and Forbes, Josephine M. (2009). Rage-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes. Journal of the American Society of Nephrology, 20 (4), 742-752. doi: 10.1681/ASN.2008050514

Rage-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes

2008

Journal Article

Heat shock protein expression in diabetic nephropathy

Barutta, Federica, Pinach, Silvia, Giunti, Sara, Vittone, Ferdinando, Forbes, Josephine M., Chiarle, Roberto, Arnstein, Maryann, Perin, Paolo Cavallo, Camussi, Giovanni, Cooper, Mark E. and Gruden, Gabriella (2008). Heat shock protein expression in diabetic nephropathy. American Journal of Physiology - Renal Physiology, 295 (6), F1817-F1824. doi: 10.1152/ajprenal.90234.2008

Heat shock protein expression in diabetic nephropathy

2008

Journal Article

Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes

Soro-Paavonen, Aino, Watson, Anna M. D., Li, Jiaze, Paavonen, Karri, Koitka, Audrey, Calkin, Anna C., Barit, David, Coughlan, Melinda T., Drew, Brian G., Lancaster, Graeme I., Thomas, Merlin, Forbes, Josephine M., Nawroth, Peter P., Bierhaus, Angelika, Cooper, Mark E. and Jandeleit-Dahm, Karin A. (2008). Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes. Diabetes, 57 (9), 2461-2469. doi: 10.2337/db07-1808

Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes

2008

Journal Article

Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs

Tikellis, Christos, Thomas, Merlin C., Harcourt, Brooke E., Coughlan, Melinda T., Pete, Josepha, Bialkowski, Katarzyna, Tan, Adeline, Bierhaus, Angelika, Cooper, Mark E. and Forbes, Josephine M. (2008). Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs. American Journal of Physiology: Endocrinology and Metabolism, 295 (2), E323-E330. doi: 10.1152/ajpendo.00024.2008

Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs

2008

Journal Article

Response to comment on: Thallas-bonke et al. (2008) inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-α-dependent pathway:Diabetes 57:460-469, 2008

Thallas-Bonke, Vicki and Forbes, Josephine M. (2008). Response to comment on: Thallas-bonke et al. (2008) inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-α-dependent pathway:Diabetes 57:460-469, 2008. Diabetes, 57 (6), e14-e14. doi: 10.2337/db08-0406

Response to comment on: Thallas-bonke et al. (2008) inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-α-dependent pathway:Diabetes 57:460-469, 2008

2008

Journal Article

Oxidative stress as a major culprit in kidney disease in diabetes

Forbes, Josephine M., Coughlan, Melinda T. and Cooper, Mark E. (2008). Oxidative stress as a major culprit in kidney disease in diabetes. Diabetes, 57 (6), 1446-1454. doi: 10.2337/db08-0057

Oxidative stress as a major culprit in kidney disease in diabetes

2008

Journal Article

MKK3 signalling plays an essential role in leukocyte-mediated pancreatic injury in the multiple low-dose streptozotocin model

Fukuda, Kyoichi, Tesch, Greg H., Yap, Felicia Y., Forbes, Josephine M., Flavell, Richard A., Davis, Roger J. and Nikolic-Paterson, David J. (2008). MKK3 signalling plays an essential role in leukocyte-mediated pancreatic injury in the multiple low-dose streptozotocin model. Laboratory Investigation, 88 (4), 398-407. doi: 10.1038/labinvest.2008.10

MKK3 signalling plays an essential role in leukocyte-mediated pancreatic injury in the multiple low-dose streptozotocin model

2008

Journal Article

Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-α-dependent pathway

Thallas-Bonke, Vicki, Thorpe, Suzanne R., Coughlan, Melinda T., Fukami, Kei, Yap, Felicia Y. T., Sourris, Karly C., Penfold, Sally A., Bach, Leon A., Cooper, Mark E. and Forbes, Josephine M. (2008). Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-α-dependent pathway. Diabetes, 57 (2), 460-469. doi: 10.2337/db07-1119

Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-α-dependent pathway

2008

Journal Article

Advanced glycation: implications in tissue damage and disease

Gasser, Anna and Forbes, Josephine M. (2008). Advanced glycation: implications in tissue damage and disease. Protein and Peptide Letters, 15 (4), 385-391. doi: 10.2174/092986608784246515

Advanced glycation: implications in tissue damage and disease

2007

Journal Article

Advanced glycation of apolipoprotein A-I impairs its anti-atherogenic properties

Hoang, A., Murphy, A. J., Coughlan, M. T., Thomas, M. C., Forbes, J. M., O'Brien, R., Cooper, M. E., Chin-Dusting, J. P. F. and Sviridov, D. (2007). Advanced glycation of apolipoprotein A-I impairs its anti-atherogenic properties. Diabetologia, 50 (8), 1770-1779. doi: 10.1007/s00125-007-0718-9

Advanced glycation of apolipoprotein A-I impairs its anti-atherogenic properties

2007

Journal Article

Combination therapy with the advanced glycation end product cross-link breaker, alagebrium, and angiotensin converting enzyme inhibitors in diabetes: synergy or redundancy?

Coughlan, Melinda T., Thallas-Bonke, Vicki, Pete, Josefa, Long, David M., Gasser, Anna, Tong, David C. K., Arnstein, Maryann, Thorpe, Suzanne R., Cooper, Mark E. and Forbes, Josephine M. (2007). Combination therapy with the advanced glycation end product cross-link breaker, alagebrium, and angiotensin converting enzyme inhibitors in diabetes: synergy or redundancy?. Endocrinology, 148 (2), 886-895. doi: 10.1210/en.2006-1300

Combination therapy with the advanced glycation end product cross-link breaker, alagebrium, and angiotensin converting enzyme inhibitors in diabetes: synergy or redundancy?

2007

Journal Article

AGE, RAGE, and ROS in diabetic nephropathy

Ton, Adeline L. Y., Forbes, Josephine M. and Cooper, Mark E. (2007). AGE, RAGE, and ROS in diabetic nephropathy. Seminars in Nephrology, 27 (2), 130-143. doi: 10.1016/j.semnephrol.2007.01.006

AGE, RAGE, and ROS in diabetic nephropathy

2007

Journal Article

Renal microvascular injury in diabetes: RAGE and redox signaling

Coughlan, Melinda T., Cooper, Mark E. and Forbes, Josephine M. (2007). Renal microvascular injury in diabetes: RAGE and redox signaling. Antioxidants and Redox Signaling, 9 (3), 331-342. doi: 10.1089/ars.2006.1469

Renal microvascular injury in diabetes: RAGE and redox signaling

2007

Journal Article

Diabetic nephropathy: where hemodynamics meets metabolism

Forbes, J. M., Fukami, K. and Cooper, M. E. (2007). Diabetic nephropathy: where hemodynamics meets metabolism. Experimental and Clinical Endocrinology and Diabetes, 115 (2), 69-84. doi: 10.1055/s-2007-949721

Diabetic nephropathy: where hemodynamics meets metabolism

2006

Journal Article

Connective tissue growth factor plays an important role in advanced glycation end product-induced tubular epithelial-to-mesenchymal transition: implications for diabetic renal disease

Burns, Wendy C., Twigg, Stephen M., Forbes, Josephine M., Pete, Josefa, Tikellis, Christos, Thallas-Bonke, Vicki, Thomas, Merlin C., Cooper, Mark E. and Kantharidis, Phillip (2006). Connective tissue growth factor plays an important role in advanced glycation end product-induced tubular epithelial-to-mesenchymal transition: implications for diabetic renal disease. Journal of the American Society of Nephrology, 17 (9), 2484-2494. doi: 10.1681/ASN.2006050525

Connective tissue growth factor plays an important role in advanced glycation end product-induced tubular epithelial-to-mesenchymal transition: implications for diabetic renal disease