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2026

Journal Article

2401-P: Genetic Regulation of Molecular Traits Enhances Precision Risk Stratification in Youth-Onset Type 2 Diabetes

D'ANTONIO, MATTEO, BJORNSTAD, PETTER, JI CHOI, YE, PYLE, LAURA, DAS, VIVEK, GRAMS, MORGAN, KELSEY, MEGAN, NELSON, ROBERT, SRINIVASAN, SHYLAJA, SULEK, KAROLINA, KIRYLUK, KRZYSZTOF, GOODRICH, JESSE, GORDIN, DANIEL, NGUYEN, ELIZABETH D., LAFFEL, LORI M., FORBES, JOSEPHINE M., HAMPSON, HAILEY, RAMESH, SHIVANI, WEISSENKAMPEN, JAMES D., NARONGKIATIKHUN, PHOOM, TOMMERDAHL, KALIE, COLE, JOANNE, KARIHALOO, ANIL and LEIDHOLT, SAVANAH L. (2026). 2401-P: Genetic Regulation of Molecular Traits Enhances Precision Risk Stratification in Youth-Onset Type 2 Diabetes. Diabetes, 75 (Supplement_1) 2401-P. doi: 10.2337/db26-2401-p

2401-P: Genetic Regulation of Molecular Traits Enhances Precision Risk Stratification in Youth-Onset Type 2 Diabetes

2026

Journal Article

Mitochondrial Alterations and CKD

Pinzon-Cortes, Jairo A., Narongkiatikhun, Phoom, Yuan, Long, Meister, Jaroslawna, Hampson, Hailey, van Raalte, Daniël, Blondin, Denis P., Capozzi, Megan, Sweet, Ian R., Nelson, Robert G., Jandeleit-Dahm, Karin, Forbes, Josephine M., Cooper, Mark E. and Bjornstad, Petter (2026). Mitochondrial Alterations and CKD. American Journal of Kidney Diseases. doi: 10.1053/j.ajkd.2026.01.021

Mitochondrial Alterations and CKD

2026

Journal Article

Process of co-designing an Aboriginal and Torres Strait Islander longitudinal birth cohort study (The Strong Families Study)

Massi, Luciana, Smith, Davina, Mohamed Ahmed, Salma, Weatherall, Loretta, Friday, Rhiannon, Dorey, Emily S., Rooney, Rebecca, Reid, Natasha, Wheeler, Kai, Boyd, Roslyn N., Benfer, Katherine, Whittingham, Koa, Callaway, Leonie, Ware, Robert S., Clifton, Vicki, Martin, Elizabeth, Robinson, Paul, Forbes, Josephine, Singh, Gurmeet, Hermith-Ramirez, Diana, Marriott, Rhonda, Eades, Anne-Marie, Toombs, Maree, Eades, Sandra, Rae, Kym M. and Strong Families Study Indigenous Steering Committee (2026). Process of co-designing an Aboriginal and Torres Strait Islander longitudinal birth cohort study (The Strong Families Study). Codesign, 1-25. doi: 10.1080/15710882.2026.2675669

Process of co-designing an Aboriginal and Torres Strait Islander longitudinal birth cohort study (The Strong Families Study)

2025

Journal Article

Round and round we go: phosphoenolpyruvate carboxykinase 1 (PCK1) in cataplerosis, mitochondrial, and kidney health

Sullivan, Mitchell A. and Forbes, Josephine M. (2025). Round and round we go: phosphoenolpyruvate carboxykinase 1 (PCK1) in cataplerosis, mitochondrial, and kidney health. Kidney International, 108 (5), 738-740. doi: 10.1016/j.kint.2025.08.006

Round and round we go: phosphoenolpyruvate carboxykinase 1 (PCK1) in cataplerosis, mitochondrial, and kidney health

2025

Journal Article

Type 1 diabetes mellitus prevention: present and future

Henriques, Francisca L., Buckle, Irina and Forbes, Josephine M. (2025). Type 1 diabetes mellitus prevention: present and future. Nature Reviews Endocrinology, 21 (10), 608-622. doi: 10.1038/s41574-025-01128-6

Type 1 diabetes mellitus prevention: present and future

2025

Conference Publication

Oral RAGE antagonists induce Tregs and anergy on effector T cells to protect against preclinical autoimmune diabetes

Buckle, I., Du, C., Fotheringham, A. K., Naranjo, J. D. Loaiza, Whiddett, R. O., Henriques, F. Leitao, McCarthy, D., LeBagge, S., Chandrashekar, P., Sullivan, M. A., Herold, K. and Forbes, J. M. (2025). Oral RAGE antagonists induce Tregs and anergy on effector T cells to protect against preclinical autoimmune diabetes. NEW YORK: SPRINGER.

Oral RAGE antagonists induce Tregs and anergy on effector T cells to protect against preclinical autoimmune diabetes

2025

Journal Article

Association between enteral carboxymethyllysine intake and daily glycemic variability in critically ill adults: a retrospective cohort study

Doola, Ra'eesa, Griffin, Alison, Forbes, Josephine M., Kruger, Peter S., Deane, Adam M., Schalkwijk, Casper G. and White, Kyle C. (2025). Association between enteral carboxymethyllysine intake and daily glycemic variability in critically ill adults: a retrospective cohort study. Journal of Parenteral and Enteral Nutrition, 49 (3), 324-331. doi: 10.1002/jpen.2727

Association between enteral carboxymethyllysine intake and daily glycemic variability in critically ill adults: a retrospective cohort study

2025

Journal Article

Efficacy and safety of photobiomodulation in MELAS: protocol for a series of N-of-1 trials

Laakso, E-Liisa, Ewais, Tatjana, McMahon, Katie, Forbes, Josephine and Phillips, Liza (2025). Efficacy and safety of photobiomodulation in MELAS: protocol for a series of N-of-1 trials. Journal of Clinical Medicine, 14 (6) 2047, 2047. doi: 10.3390/jcm14062047

Efficacy and safety of photobiomodulation in MELAS: protocol for a series of N-of-1 trials

2025

Journal Article

Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2/M arrest and cellular senescence during hypoxic kidney injury

Giuliani, Kurt T. K., Nag, Purba, Adams, Benjamin C., Wang, Xiangju, Hong, Seokchan, Grivei, Anca, Johnston, Rebecca L., Waddell, Nicola, Ho, Kenneth K. C., Tian, Yilin, Khan, Muhammad Ali, Kim, Chang Seong, Ng, Monica S. Y., Gobe, Glenda, Ungerer, Jacobus P. J., Forbes, Josephine M., Healy, Helen G. and Kassianos, Andrew J. (2025). Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2/M arrest and cellular senescence during hypoxic kidney injury. Cell Death and Disease, 16 (1) 61, 1-12. doi: 10.1038/s41419-025-07386-6

Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2/M arrest and cellular senescence during hypoxic kidney injury

2024

Journal Article

Kidney hyperfiltration and mitochondrial changes are associated with eGFR decline in young people with type 1 diabetes

Pham, Uyen N., Pryke, Alison, Baskerville, Tracey, Griffin, Alison, Whiddett, Rani O., Fotheringham, Amelia K., Sullivan, Mitchell A., Nisbet, Janelle, Phillips, Liza, Francis, Ross S., Davis, Elizabeth, Jones, Timothy W., Cameron, Fergus, Couper, Jennifer, Benitez-Aguirre, Paul, Craig, Maria, Johnson, David W., Dalton, R. Neil, Marcovecchio, M. Loredana, Cotterill, Andrew, Barrett, Helen L., Donaghue, Kim C. and Forbes, Josephine M. (2024). Kidney hyperfiltration and mitochondrial changes are associated with eGFR decline in young people with type 1 diabetes. The Journal of Clinical Endocrinology and Metabolism, 110 (8), 2243-2251. doi: 10.1210/clinem/dgae787

Kidney hyperfiltration and mitochondrial changes are associated with eGFR decline in young people with type 1 diabetes

2024

Conference Publication

Advanced glycation end-products (AGEs) in nutrition support are associated with patient outcomes

Doola, Raeesa, Griffin, Alison, Forbes, Josephine, Kruger, Peter, Deane, Adam and White, Kyle (2024). Advanced glycation end-products (AGEs) in nutrition support are associated with patient outcomes. Australian and New Zealand Intensive Care Society/Australian College of Critical Care Nursing Intensive Care Annual Scientific meeting, Brisbane, QLD, Australia, 10-12 April 2024. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.aucc.2024.07.031

Advanced glycation end-products (AGEs) in nutrition support are associated with patient outcomes

2024

Journal Article

Glucagon-like peptide-1 receptor signaling modifies the extent of diabetic kidney disease through dampening the receptor for advanced glycation end products–induced inflammation

Sourris, Karly C., Ding, Yi, Maxwell, Scott S., Al-sharea, Annas, Kantharidis, Phillip, Mohan, Muthukumar, Rosado, Carlos J., Penfold, Sally A., Haase, Claus, Xu, Yangsong, Forbes, Josephine M., Crawford, Simon, Ramm, Georg, Harcourt, Brooke E., Jandeleit-Dahm, Karin, Advani, Andrew, Murphy, Andrew J., Timmermann, Daniel B., Karihaloo, Anil, Knudsen, Lotte Bjerre, El-Osta, Assam, Drucker, Daniel J., Cooper, Mark E. and Coughlan, Melinda T. (2024). Glucagon-like peptide-1 receptor signaling modifies the extent of diabetic kidney disease through dampening the receptor for advanced glycation end products–induced inflammation. Kidney International, 105 (1), 132-149. doi: 10.1016/j.kint.2023.09.029

Glucagon-like peptide-1 receptor signaling modifies the extent of diabetic kidney disease through dampening the receptor for advanced glycation end products–induced inflammation

2023

Journal Article

Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes

Leung, Sherman S., Lenchik, Nataliya, Mathews, Clayton, Pugliese, Alberto, McCarthy, Domenica A., Le Bagge, Selena, Ewing, Adam, Harris, Mark, Radford, Kristen J., Borg, Danielle J., Gerling, Ivan and Forbes, Josephine M. (2023). Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes. Scientific Reports, 13 (1) 12948, 1-15. doi: 10.1038/s41598-023-39243-x

Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes

2023

Conference Publication

Redox Modulating Small Molecule Improves Diabetic Kidney Disease In The DB/DB Model Of Type 2 Diabetes

Fotheringham, Amelia, Masagos, Hakeem, Whiddett, Rani, McCarthy, Domenica, Chandrashekar, Preeti, Buckle, Irina, Tse, Brian, Sokolowski, Kamil, Sullivan, Mitchell and Forbes, Josephine (2023). Redox Modulating Small Molecule Improves Diabetic Kidney Disease In The DB/DB Model Of Type 2 Diabetes. 58th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Christchurch, New Zealand, 4–6 September 2023. Richmond, VIC Australia: John Wiley & Sons.

Redox Modulating Small Molecule Improves Diabetic Kidney Disease In The DB/DB Model Of Type 2 Diabetes

2023

Conference Publication

Youth with type 1 diabetes at higher risk of developing diabetic kidney disease have alterations in their urine and plasma metabolomic and mitochondrial dna profiles

Sullivan, Mitchell, Pham, Uyen, McCarthy, Domenica, Flemming, Nicole, Fotheringham, Amelia, Chandrashekar, Preeti, Whiddett, Rani, Buckle, Irina, Summers, Kim, Hodson, Mark, de Silva, Neisha, Nisbet, Janelle, Morton, Adam, Teasedale, Stephanie, Doomun, Sheik, de Souza, David, Isbel, Nicole, Jones, Timothy, Couper, Jennifer, Coughlan, Melinda, Johnson, David, O'Moore-Sullivan, Trisha, Barret, Helen, Marcovecchio, M. Loredana, Donaghue, Kim and Forbes, Josephine (2023). Youth with type 1 diabetes at higher risk of developing diabetic kidney disease have alterations in their urine and plasma metabolomic and mitochondrial dna profiles. 58th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Christchurch, New Zealand, 4-6 September 2023. Richmond, VIC Australia: John Wiley & Sons.

Youth with type 1 diabetes at higher risk of developing diabetic kidney disease have alterations in their urine and plasma metabolomic and mitochondrial dna profiles

2023

Conference Publication

Hypoxia and interleukin (IL)-1β synergistically induce cellular senescence in human proximal tubular epithelial cells (PTEC)

Kassianos, Andrew J., Giuliani, Kurt, Nag, Purba, Hong, Seokchan, Wang, Xiangju, Johnston, Rebecca L., Adams, Benjamin, Grivei, Anca, Ho, Kenneth, Ng, Monica, Waddell, Nicola, Forbes, Josephine M., Healy, Helen and Kassianos, Andrew J. (2023). Hypoxia and interleukin (IL)-1β synergistically induce cellular senescence in human proximal tubular epithelial cells (PTEC). 58th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Christchurch, New Zealand, 4-6 September 2023. Richmond, VIC, Australia: John Wiley & Sons. doi: 10.1111/nep.14216

Hypoxia and interleukin (IL)-1β synergistically induce cellular senescence in human proximal tubular epithelial cells (PTEC)

2022

Journal Article

RAGE antagonism with azeliragon improves xenograft rejection by T cells in humanized mice

Joshi, Aditi A., Wu, Ying, Deng, Songyan, Preston-Hurlburt, Paula, Forbes, Josephine M. and Herold, Kevan C. (2022). RAGE antagonism with azeliragon improves xenograft rejection by T cells in humanized mice. Clinical Immunology, 245 109165, 1-6. doi: 10.1016/j.clim.2022.109165

RAGE antagonism with azeliragon improves xenograft rejection by T cells in humanized mice

2022

Book Chapter

The role of the receptor for advanced glycation endproducts (RAGE) in type 1 diabetes: an immune cell perspective

Buckle, Irina and Forbes, Josephine M. (2022). The role of the receptor for advanced glycation endproducts (RAGE) in type 1 diabetes: an immune cell perspective. Type 1 diabetes in 2023 - from real practice to open questions. (pp. 1-20) edited by Rudolf Chlup. London, United Kingdom: IntechOpen. doi: 10.5772/intechopen.108528

The role of the receptor for advanced glycation endproducts (RAGE) in type 1 diabetes: an immune cell perspective

2022

Journal Article

Advanced glycation end products and inflammation in type 1 diabetes development

Du, Chenping, Whiddett, Rani O., Buckle, Irina, Chen, Chen, Forbes, Josephine M. and Fotheringham, Amelia K. (2022). Advanced glycation end products and inflammation in type 1 diabetes development. Cells, 11 (21) 3503, 1-18. doi: 10.3390/cells11213503

Advanced glycation end products and inflammation in type 1 diabetes development

2022

Conference Publication

Mitochondrial dysfunction aligns with risk for diabetic kidney disease in youth with type 1 diabetes

Sullivan, Mitchell, McCarthy, Domenica, Flemming, Nicole, Chandrashekar, Preeti, Hodson, Mark, Fotheringham, Amelia, Whiddett, Rani, De Silva, Neisha, Nisbet, Jinelle, Morton, Adam, Teasdale, Stephanie, Isbel, Nicole, Jones, Timothy, Couper, Jennier, Thorburn, David, Johnson, David, Cotterill, Andrew, Barrett, Helen, O'Moore-Sullivan, Trisha, Donaghue, Kim and Forbes, Josephine (2022). Mitochondrial dysfunction aligns with risk for diabetic kidney disease in youth with type 1 diabetes. 57th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Sydney, NSW, Australia, 17–19 October 2022. Richmond, VIC, Australia: John Wiley & Sons.

Mitochondrial dysfunction aligns with risk for diabetic kidney disease in youth with type 1 diabetes