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2025 Journal Article Development of a high-affinity anti-ROR1 variable region for broad anti-cancer immunotherapyWong, Joshua K. M., Lam, Pui Yeng, Coleborn, Elaina, Alim, Louisa, Jose, Jiya, Tu, Cui, Antczak, Magdalena, Dietmair, Bettina, Hagh, Arghavan Golbaz, Noronha, Lucia, Cheetham, Seth W., Hooper, John, Beavis, Paul A., Merino, Delphine, Berthelet, Jean, Aoude, Lauren G., McCart-Reed, Amy E., Lakhani, Sunil, Simpson, Peter T., Rossi, Gustavo R., Brooks, Andrew J., Jones, Martina L., Simpson, Fiona and Souza-Fonseca-Guimaraes, Fernando (2025). Development of a high-affinity anti-ROR1 variable region for broad anti-cancer immunotherapy. Molecular therapy. doi: 10.1016/j.ymthe.2025.11.021 |
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2025 Journal Article A novel chimeric coronavirus spike vaccine combining SARS-CoV-2 RBD and scaffold domains from HKU-1 elicits potent neutralising antibody responsesZoest, Veronica P., Lee, Wen Shi, Murdiyarso, Lydia, Burmas, Lauren, Pymm, Phillip, Esterbauer, Robyn, Kelly, Andrew, Kelly, Hannah G., Barber-Axthelm, Isaac, Cooney, James P., Davidson, Kathryn C., Dayton, Merle, McAleese, Courtney E., Gillard, Marianne, Hughes, Karen, Jones, Martina L., Pellegrini, Marc, Tham, Wai-Hong, Hughes, Ben, Kent, Stephen J., Wheatley, Adam K., Juno, Jennifer A. and Tan, Hyon-Xhi (2025). A novel chimeric coronavirus spike vaccine combining SARS-CoV-2 RBD and scaffold domains from HKU-1 elicits potent neutralising antibody responses. npj Vaccines, 10 (1) 275, 1-14. doi: 10.1038/s41541-025-01323-6 |
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2025 Journal Article Safety and immunogenicity of a SARS-CoV-2 spike, subunit vaccine stabilised in the prefusion conformation by second generation Molecular Clamp evaluated in adults aged 18–55 years: a randomised, double-blind, active comparator, Phase I trialChappell, Keith J., Mordant, Francesca L., Amarilla, Alberto A., Modhiran, Naphak, Liang, Benjamin, Li, Zheyi, Lackenby, Julia A., Jaberolansar, Noushin, O’Donnell, Jake, Kienzle, Vivian, Kommajosyula, Varsha, Tardiota, Nicolas, Bennet, Jillian K., Henderson, Christina L., Dalrymple, Rhiannon L., Goh, Justin, Hoger, Kym, Gillard, Marianne, Jones, Martina L., Hughes, Karen, Hughes, Ben, Barnes, James, Reading, Patrick C., Ranasinghe, Charani, Subbarao, Kanta, Munro, Trent P., Young, Paul R. and Watterson, Daniel (2025). Safety and immunogenicity of a SARS-CoV-2 spike, subunit vaccine stabilised in the prefusion conformation by second generation Molecular Clamp evaluated in adults aged 18–55 years: a randomised, double-blind, active comparator, Phase I trial. The Journal of Infectious Diseases jiaf568. doi: 10.1093/infdis/jiaf568 |
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2025 Conference Publication Chimeric coronavirus spike combining SARS-CoV-2 RBD and scaffold domains from HKU-1 elicits potent T helper cell and neutralising antibody responses in murine and non-human primate modelsTan, Hyon-Xhi, Zoest, Veronica, Lee, Wen Shi, Murdiyarso, Lydia, Burmas, Lauren, Gibbon, Anne, Barber-Axthelm, Isaac Michael, Kelly, Andrew, Esterbauer, Robyn, Jones, Martina, Hughes, Ben, Kent, Stephen J., Juno, Jennifer and Wheatley, Adam (2025). Chimeric coronavirus spike combining SARS-CoV-2 RBD and scaffold domains from HKU-1 elicits potent T helper cell and neutralising antibody responses in murine and non-human primate models. IMMUNOLOGY2025, Honolulu, HI United States, 3-7 May 2024. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/jimmun/vkaf283.2295 |
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2025 Journal Article A nanobody-based therapeutic targeting Nipah virus limits viral escapeIsaacs, Ariel, Nieto, Guillermo Valenzuela, Zhang, Xinghai, Modhiran, Naphak, Barr, Jennifer, Thakur, Nazia, Low, Yu Shang, Parry, Rhys H., Barnes, James B., Jara, Ronald, Himelreichs, Johanna, Yao, Yanfeng, Deride, Camila, Barthou-Gatica, Barbara, Salinas-Rebolledo, Constanza, Ehrenfeld, Pamela, Hen, Jun Jet, Hayes, Noah, Paramitha, Devina, Morgan, Mahali S., McMillan, Christopher L. D., Jones, Martina L., Munro, Trent P., Khromykh, Alexander A., Reading, Patrick C., Young, Paul R., Chappell, Keith J., Shi, Yi, Bailey, Dalan ... Watterson, Daniel (2025). A nanobody-based therapeutic targeting Nipah virus limits viral escape. Nature Structural and Molecular Biology, 32 (10), 1920-1931. doi: 10.1038/s41594-025-01598-2 |
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2020 Journal Article Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 studyPlayford, Elliott Geoffrey, Munro, Trent, Mahler, Stephen M., Elliott, Suzanne, Gerometta, Michael, Hoger, Kym L., Jones, Martina L., Griffin, Paul, Lynch, Kathleen D., Carroll, Heidi, El Saadi, Debra, Gilmour, Margaret E., Hughes, Benjamin, Hughes, Karen, Huang, Edwin, de Bakker, Christopher, Klein, Reuben, Scher, Mark G., Smith, Ina L., Wang, Lin-Fa, Lambert, Stephen B., Dimitrov, Dimiter S., Gray, Peter P. and Broder, Christopher C. (2020). Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study. The Lancet Infectious Diseases, 20 (4), 445-454. doi: 10.1016/S1473-3099(19)30634-6 |
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2019 Journal Article Retooling phage display with electrohydrodynamic nanomixing and nanopore sequencingRaftery, Lyndon J., Howard, Christopher B., Grewal, Yadveer S., Vaidyanathan, Ramanathan, Jones, Martina L., Anderson, Will, Korbie, Darren, Duarte, Tania, Duc Cao, Minh, Nguyen, Son Hoang, Coin, Lachlan JM, Mahler, Stephen M and Trau, Matt (2019). Retooling phage display with electrohydrodynamic nanomixing and nanopore sequencing. Lab on a Chip, 19 (24), 4083-4092. doi: 10.1039/c9lc00978g |
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2019 Journal Article Wavelength-dependent fluorescent immunosensors via incorporation of polarity indicators near the binding interface of antibody fragmentsIslam, Jiaul, Riley, Blake T., Fercher, Christian, Jones, Martina L., Buckle, Ashley M., Howard, Christopher B., Cox, Rosalind P., Bell, Toby D. M., Mahler, Stephen and Corrie, Simon R. (2019). Wavelength-dependent fluorescent immunosensors via incorporation of polarity indicators near the binding interface of antibody fragments. Analytical Chemistry, 91 (12), 7631-7638. doi: 10.1021/acs.analchem.9b00445 |
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2019 Journal Article Use of bacteriophage for discovery of therapeutically relevant antibodies against infectious diseasesJones, Martina L. (2019). Use of bacteriophage for discovery of therapeutically relevant antibodies against infectious diseases. Microbiology Australia, 40 (1), 33-36. doi: 10.1071/MA19007 |
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2019 Journal Article Canine CD117-Specific Antibodies with Diverse Binding Properties Isolated from a Phage Display Library Using Cell-Based BiopanningAlfaleh, Mohamed, Arora, Neetika, Yeh, Michael, de Bakker, Christopher, Howard, Christopher, Macpherson, Philip, Allavena, Rachel, Chen, Xiaoli, Harkness, Linda, Mahler, Stephen and Jones, Martina (2019). Canine CD117-Specific Antibodies with Diverse Binding Properties Isolated from a Phage Display Library Using Cell-Based Biopanning. Antibodies, 8 (1) 15, 15. doi: 10.3390/antib8010015 |
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2019 Conference Publication In silico model for glycophorin a (GPA) structureEkman, Serena, Flower, Robert, Hyland, Catherine, Mahler, Stephen, Jones, Martina, Treutlein, Herbert and Bui, Xuan (2019). In silico model for glycophorin a (GPA) structure. Pathology Update 2019, Melbourne, VIC Australia, 22- 24 February 2019. London, United Kingdom: Lippincott Williams & Wilkins. doi: 10.1016/j.pathol.2018.12.352 |
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2019 Conference Publication Innovation in diagnosis and treatment of brain metastases using multifunctional nanomedicinesSaunus, J. M., Lim, M., Puttick, S., Croft, P. Kalita-de, Houston, Z. H., Jones, M. L., Latter, M. J., Campbell, L. C., Thomas, P., Jeffree, R. L., Rose, S. E., Mahler, S. M., Thurecht, K. J., Scott, A. M. and Lakhani, S. R. (2019). Innovation in diagnosis and treatment of brain metastases using multifunctional nanomedicines. San Antonio Breast Cancer Symposium, San Antonio, Texas, 4-8 December 2018. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS18-P1-19-02 |
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2019 Conference Publication Identification of novel monoclonal antibodies recognising JENU and U antigens of the MNS blood group systemEkman, Serena, Flower, Robert, Hyland, Catherine, Mahler, Stephen, Jones, Martina and Bui, Xuan (2019). Identification of novel monoclonal antibodies recognising JENU and U antigens of the MNS blood group system. Pathology Update 2019, Melbourne, VIC Australia, 22- 24 February 2019. London, United Kingdom: Lippincott Williams & Wilkins. doi: 10.1016/j.pathol.2018.12.353 |
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2019 Conference Publication In silico modelling of glycophorin MNS system blood group antigensFlower, R., Ekman, S., Mahler, S., Jones, M., Malde, A. K. and Bui, X. (2019). In silico modelling of glycophorin MNS system blood group antigens. In: ANZSBT, Perth, Australia, (24-25). 20-23 October 2019. |
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2018 Journal Article CD83 antibody inhibits human B cell responses to antigen as well as dendritic cell-mediated CD4 T cell responsesWong, Kuan Y., Baron, Rebecca, Seldon, Therese A., Jones, Martina L., Rice, Alison M. and Munster, David J. (2018). CD83 antibody inhibits human B cell responses to antigen as well as dendritic cell-mediated CD4 T cell responses. Journal of Immunology, 200 (10), 3383-3396. doi: 10.4049/jimmunol.1700064 |
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2018 Journal Article Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approachFontaine, Frank R., Goodall, Stephen, Prokop, Jeremy W., Howard, Christopher B., Moustaqil, Mehdi, Kumble, Sumukh, Rasicci, Daniel T., Osborne, Geoffrey W., Gambin, Yann, Sierecki, Emma, Jones, Martina L., Zuegg, Johannes, Mahler, Stephen and Francois, Mathias (2018). Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach. mAbs, 10 (4), 1-11. doi: 10.1080/19420862.2018.1451288 |
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2018 Book Chapter Selection of antibodies to transiently expressed membrane proteins using phage displayJones, Martina L., Mahler, Stephen M. and Kumble, Sumukh (2018). Selection of antibodies to transiently expressed membrane proteins using phage display. Antibody engineering. (pp. 179-195) edited by Damien Nevoltris and Patrick Chames. New York, NY, United States: Springer. doi: 10.1007/978-1-4939-8648-4_10 |
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2017 Journal Article Targeting mesothelin receptors with drug-loaded bacterial nanocells suppresses human mesothelioma tumour growth in mouse xenograft modelsAlfaleh, Mohamed A., Howard, Christopher B., Sedliarou, Ilya, Jones, Martina L., Gudhka, Reema, Vanegas, Natasha, Weiss, Jocelyn, Suurbach, Julia H., de Bakker, Christopher J., Milne, Michael R., Rumballe, Bree A., MacDiarmid, Jennifer A., Brahmbhatt, Himanshu and Mahler, Stephen M. (2017). Targeting mesothelin receptors with drug-loaded bacterial nanocells suppresses human mesothelioma tumour growth in mouse xenograft models. Plos One, 12 (10) e0186137, e0186137. doi: 10.1371/journal.pone.0186137 |
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2017 Journal Article Strategies for Selecting Membrane Protein-Specific Antibodies using Phage Display with Cell-Based PanningAlfaleh, Mohamed A., Jones, Martina L., Howard, Christopher B. and Mahler, Stephen M. (2017). Strategies for Selecting Membrane Protein-Specific Antibodies using Phage Display with Cell-Based Panning. Antibodies, 6 (3) 10, 1-19. doi: 10.3390/antib6030010 |
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2017 Journal Article Isolation of serotype-specific antibodies against dengue virus non-structural protein 1 using phage display and application in a multiplexed serotyping assayLebani, Kebaneilwe, Jones, Martina L., Watterson, Daniel, Ranzoni, Andrea, Traves, Renee J., Young, Paul R. and Mahler, Stephen M. (2017). Isolation of serotype-specific antibodies against dengue virus non-structural protein 1 using phage display and application in a multiplexed serotyping assay. PLoS One, 12 (7) e0180669, e0180669. doi: 10.1371/journal.pone.0180669 |
