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2025 Journal Article Development of a high-affinity anti-ROR1 variable region for broad anti-cancer immunotherapyWong, Joshua K. M., Lam, Pui Yeng, Coleborn, Elaina, Jose, Jiya, Alim, Louisa, Tu, Cui, Antczak, Magdalena, Dietmair, Bettina, Hagh, Arghavan Golbaz, Noronha, Lucia, Cheetham, Seth W., Hooper, John, Beavis, Paul A., Merino, Delphine, Berthelet, Jean, Aoude, Lauren G., McCart-Reed, Amy E., Lakhani, Sunil, Simpson, Peter T., Rossi, Gustavo R., Brooks, Andrew J, Jones, Martina L, Simpson, Fiona and Souza-Fonseca-Guimaraes, Fernando (2025). Development of a high-affinity anti-ROR1 variable region for broad anti-cancer immunotherapy. Molecular therapy. doi: 10.1016/j.ymthe.2025.11.021 |
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2025 Journal Article A novel chimeric coronavirus spike vaccine combining SARS-CoV-2 RBD and scaffold domains from HKU-1 elicits potent neutralising antibody responsesZoest, Veronica P., Lee, Wen Shi, Murdiyarso, Lydia, Burmas, Lauren, Pymm, Phillip, Esterbauer, Robyn, Kelly, Andrew, Kelly, Hannah G., Barber-Axthelm, Isaac, Cooney, James P., Davidson, Kathryn C., Dayton, Merle, McAleese, Courtney E., Gillard, Marianne, Hughes, Karen, Jones, Martina L., Pellegrini, Marc, Tham, Wai-Hong, Hughes, Ben, Kent, Stephen J., Wheatley, Adam K., Juno, Jennifer A. and Tan, Hyon-Xhi (2025). A novel chimeric coronavirus spike vaccine combining SARS-CoV-2 RBD and scaffold domains from HKU-1 elicits potent neutralising antibody responses. npj Vaccines. doi: 10.1038/s41541-025-01323-6 |
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2025 Journal Article Safety and immunogenicity of a SARS-CoV-2 spike, subunit vaccine stabilised in the prefusion conformation by second generation Molecular Clamp evaluated in adults aged 18–55 years: a randomised, double-blind, active comparator, Phase I trialChappell, Keith J., Mordant, Francesca L., Amarilla, Alberto A., Modhiran, Naphak, Liang, Benjamin, Li, Zheyi, Lackenby, Julia A., Jaberolansar, Noushin, O’Donnell, Jake, Kienzle, Vivian, Kommajosyula, Varsha, Tardiota, Nicolas, Bennet, Jillian K., Henderson, Christina L., Dalrymple, Rhiannon L., Goh, Justin, Hoger, Kym, Gillard, Marianne, Jones, Martina L., Hughes, Karen, Hughes, Ben, Barnes, James, Reading, Patrick C., Ranasinghe, Charani, Subbarao, Kanta, Munro, Trent P., Young, Paul R. and Watterson, Daniel (2025). Safety and immunogenicity of a SARS-CoV-2 spike, subunit vaccine stabilised in the prefusion conformation by second generation Molecular Clamp evaluated in adults aged 18–55 years: a randomised, double-blind, active comparator, Phase I trial. The Journal of Infectious Diseases jiaf568. doi: 10.1093/infdis/jiaf568 |
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2025 Conference Publication Chimeric coronavirus spike combining SARS-CoV-2 RBD and scaffold domains from HKU-1 elicits potent T helper cell and neutralising antibody responses in murine and non-human primate modelsTan, Hyon-Xhi, Zoest, Veronica, Lee, Wen Shi, Murdiyarso, Lydia, Burmas, Lauren, Gibbon, Anne, Barber-Axthelm, Isaac Michael, Kelly, Andrew, Esterbauer, Robyn, Jones, Martina, Hughes, Ben, Kent, Stephen J., Juno, Jennifer and Wheatley, Adam (2025). Chimeric coronavirus spike combining SARS-CoV-2 RBD and scaffold domains from HKU-1 elicits potent T helper cell and neutralising antibody responses in murine and non-human primate models. OXFORD: OXFORD UNIV PRESS. doi: 10.1093/jimmun/vkaf283.2295 |
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2025 Journal Article A nanobody-based therapeutic targeting Nipah virus limits viral escapeIsaacs, Ariel, Nieto, Guillermo Valenzuela, Zhang, Xinghai, Modhiran, Naphak, Barr, Jennifer, Thakur, Nazia, Low, Yu Shang, Parry, Rhys H., Barnes, James B., Jara, Ronald, Himelreichs, Johanna, Yao, Yanfeng, Deride, Camila, Barthou-Gatica, Barbara, Salinas-Rebolledo, Constanza, Ehrenfeld, Pamela, Hen, Jun Jet, Hayes, Noah, Paramitha, Devina, Morgan, Mahali S., McMillan, Christopher L. D., Jones, Martina L., Munro, Trent P., Khromykh, Alexander A., Reading, Patrick C., Young, Paul R., Chappell, Keith J., Shi, Yi, Bailey, Dalan ... Watterson, Daniel (2025). A nanobody-based therapeutic targeting Nipah virus limits viral escape. Nature Structural and Molecular Biology, 32 (10), 1920-1931. doi: 10.1038/s41594-025-01598-2 |
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2024 Journal Article Isolation and Characterization of Antibodies Against Vascular Cell Adhesion Molecule-1 Reveals Putative Role for Ig-like Domains 2 and 3 in Cell-to-Cell InteractionPerera, Binura, Wu, Yuao, Pickett, Jessica R., Panagides, Nadya, Barretto, Francisca M., Fercher, Christian, Sester, David P., Jones, Martina L., Ta, Hang T. and Zacchi, Lucia F. (2024). Isolation and Characterization of Antibodies Against Vascular Cell Adhesion Molecule-1 Reveals Putative Role for Ig-like Domains 2 and 3 in Cell-to-Cell Interaction. International Journal of Molecular Sciences, 25 (24) 13650, 1-21. doi: 10.3390/ijms252413650 |
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2024 Journal Article Analysis of bovine lactoferrin in infant formula and adult nutritional products by optical biosensor immunoassay: collaborative study, final action AOAC 2021.07Gill, Brendon D, Indyk, Harvey E, Kobayashi, Tadashi, Wood, Jackie E, Clow, Fiona, Dolezal, Olan, Hartley-Tassell, Lauren, Jones, Martina, Kelton, William, Stoller, Robyn and Wilkinson-White, Lorna (2024). Analysis of bovine lactoferrin in infant formula and adult nutritional products by optical biosensor immunoassay: collaborative study, final action AOAC 2021.07. Journal of AOAC International, 107 (5), 833-838. doi: 10.1093/jaoacint/qsae042 |
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2024 Journal Article Characterization of novel Rh variant (CETW) associated with haemolytic disease of fetus and newborn using recombinant technologyZhao, Shen, Radenkovic, Filip, Flower, Robert, Zacchi, Lucia, Jones, Martina, Wilson, Brett, Liew, Yew Wah, Tung, John-Paul and Hyland, Catherine (2024). Characterization of novel Rh variant (CETW) associated with haemolytic disease of fetus and newborn using recombinant technology. Pathology, 56 (Supplement 1), S100-S100. doi: 10.1016/j.pathol.2023.12.336 |
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2023 Journal Article Limited potential of sheep as a large animal to model transfusion-related acute lung injury mediated by antibodies against human neutrophil antigen 3aRadenkovic, Filip, Burton, Mark, Hassell, Penny, Chiaretti, Sara, Bui, Xuan, Zhao, Shen, Jones, Martina, Flower, Robert and Tung, John-Paul (2023). Limited potential of sheep as a large animal to model transfusion-related acute lung injury mediated by antibodies against human neutrophil antigen 3a. Annals of Blood, 9 26, 1-9. doi: 10.21037/aob-23-57 |
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2023 Journal Article A nanobody recognizes a unique conserved epitope and potently neutralizes against the SARS-CoV-2 omicron variantsModhiran, Naphak, Lauer, Simon Malte, Amarilla, Alberto A., Hewins, Peter, Lopes van den Broek, Sara Irene, Low, Yu Shang, Thakur, Nazia, Liang, Benjamin, Nieto, Guillermo Valenzuela, Jung, James, Paramitha, Devina, Isaacs, Ariel, Sng, Julian D. J., Song, David, Jørgensen, Jesper Tranekjær, Cheuquemilla, Yorka, Bürger, Jörg, Andersen, Ida Vang, Himelreichs, Johanna, Jara, Ronald, MacLoughlin, Ronan, Miranda-Chacon, Zaray, Chana-Cuevas, Pedro, Kramer, Vasko, Spahn, Christian M. T., Mielke, Thorsten, Khromykh, Alexander A., Munro, Trent, Jones, Martina L. ... Watterson, Daniel (2023). A nanobody recognizes a unique conserved epitope and potently neutralizes against the SARS-CoV-2 omicron variants. iScience, 26 (7) 107085, 107085. doi: 10.1016/j.isci.2023.107085 |
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2023 Journal Article Design of polarity-dependent immunosensors based on the structural analysis of engineered antibodiesIslam, Jiaul, Conroy, Paul, Fercher, Christian, Kim, Mijin, Yaari, Zvi, Jones, Martina, Bell, Toby D. M., Caradoc-Davies, Tom, Law, Ruby, Whisstock, James, Heller, Daniel, Mahler, Stephen and Corrie, Simon (2023). Design of polarity-dependent immunosensors based on the structural analysis of engineered antibodies. ACS Chemical Biology, 18 (8), 1863-1871. doi: 10.1021/acschembio.3c00303 |
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2022 Journal Article Evaluation of phage display biopanning strategies for the selection of anti-cell surface receptor antibodiesPanagides, Nadya, Zacchi, Lucia F., Souza, Mitchell J. De, Morales, Rodrigo A. V., Karnowski, Alexander, Liddament, Mark T., Owczarek, Catherine M., Mahler, Stephen M., Panousis, Con, Jones, Martina L. and Fercher, Christian (2022). Evaluation of phage display biopanning strategies for the selection of anti-cell surface receptor antibodies. International Journal of Molecular Sciences, 23 (15) 8470, 8470. doi: 10.3390/ijms23158470 |
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2021 Journal Article Preclinical Evaluation of a Fluorescent Probe Targeting Receptor CDCP1 for Identification of Ovarian CancerHe, Yaowu, Khan, Tashbib, Kryza, Thomas, Jones, Martina L., Goh, Justin B., Lyons, Nicholas J., Pearce, Lesley A., Lee, Michael D, Gough, Madeline, Rogers, Rebecca, Davies, Claire M,, Gilks, C. Blake, Hodgkinson, Thomas, Lourie, Rohan, Barry, Sinead C., Perrin, Lewis C., Williams, Charlotte C., Puttick, Simon, Adams, Timothy E., Munro, Trent P., Hooper, John D. and Chetty, Naven (2021). Preclinical Evaluation of a Fluorescent Probe Targeting Receptor CDCP1 for Identification of Ovarian Cancer. Molecular Pharmaceutics, 18 (9) acs.molpharmaceut.1c00401, 3464-3474. doi: 10.1021/acs.molpharmaceut.1c00401 |
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2021 Journal Article In silico molecular dynamics of human glycophorin A (GPA) extracellular structureEkman, Serena, Flower, Robert, Mahler, Stephen, Gould, Alison, Barnard, Ross T., Hyland, Catherine, Jones, Martina, Malde, Alpeshkumar K. and Bui, Xuan T. (2021). In silico molecular dynamics of human glycophorin A (GPA) extracellular structure. Annals of Blood, 6 (June) 11. doi: 10.21037/aob-20-51 |
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2021 Journal Article Preclinical development of a molecular clamp-stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2Watterson, Daniel, Wijesundara, Danushka K., Modhiran, Naphak, Mordant, Francesca L., Li, Zheyi, Avumegah, Michael S., McMillan, Christopher L. D., Lackenby, Julia, Guilfoyle, Kate, van Amerongen, Geert, Stittelaar, Koert, Cheung, Stacey T. M., Bibby, Summa, Daleris, Mallory, Hoger, Kym, Gillard, Marianne, Radunz, Eve, Jones, Martina L., Hughes, Karen, Hughes, Ben, Goh, Justin, Edwards, David, Scoble, Judith, Pearce, Lesley, Kowalczyk, Lukasz, Phan, Tram, La, Mylinh, Lu, Louis, Pham, Tam ... Chappell, Keith J. (2021). Preclinical development of a molecular clamp-stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2. Clinical & Translational Immunology, 10 (4) e1269, e1269. doi: 10.1002/cti2.1269 |
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2021 Journal Article Recombinant antibody engineering enables reversible binding for continuous protein biosensingFercher, Christian, Jones, Martina L., Mahler, Stephen M. and Corrie, Simon R (2021). Recombinant antibody engineering enables reversible binding for continuous protein biosensing. ACS Sensors, 6 (3) acssensors.0c01510, 764-776. doi: 10.1021/acssensors.0c01510 |
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2021 Journal Article Incorporation of unnatural amino acid into antibody fragment for creating a stable antibody-drug conjugateWardiana, Andri, Jones, Martina L., Mahler, Stephen M. and Howard, Christopher B. (2021). Incorporation of unnatural amino acid into antibody fragment for creating a stable antibody-drug conjugate. Indonesian Journal of Pharmacy, 32 (1), 96-105. doi: 10.22146/ijp.1101 |
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2020 Journal Article Aggregates in blood filter chambers used from the plasma donations of anti-D donors: evaluation for monoclonal antibody discovery using phage displayMcGowan, Eunike C., Flower, Robert L., Jones, Martina L., Irving, David O., Barnard, Ross T., Hyland, Catherine A., Mahler, Stephen M. and Bui, Xuan T. (2020). Aggregates in blood filter chambers used from the plasma donations of anti-D donors: evaluation for monoclonal antibody discovery using phage display. Blood Transfusion , 19 (1), 64-72. doi: 10.2450/2020.0093-20 |
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2020 Journal Article Phage display derived monoclonal antibodies: from bench to bedsideAlfaleh, Mohamed A., Alsaab, Hashem O., Mahmoud, Ahmad Bakur, Alkayyal, Almohanad A., Jones, Martina L., Mahler, Stephen M. and Hashem, Anwar M. (2020). Phage display derived monoclonal antibodies: from bench to bedside. Frontiers in Immunology, 11 1986, 1986. doi: 10.3389/fimmu.2020.01986 |
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2020 Journal Article Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 studyPlayford, Elliott Geoffrey, Munro, Trent, Mahler, Stephen M., Elliott, Suzanne, Gerometta, Michael, Hoger, Kym L., Jones, Martina L., Griffin, Paul, Lynch, Kathleen D., Carroll, Heidi, El Saadi, Debra, Gilmour, Margaret E., Hughes, Benjamin, Hughes, Karen, Huang, Edwin, de Bakker, Christopher, Klein, Reuben, Scher, Mark G., Smith, Ina L., Wang, Lin-Fa, Lambert, Stephen B., Dimitrov, Dimiter S., Gray, Peter P. and Broder, Christopher C. (2020). Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study. The Lancet Infectious Diseases, 20 (4), 445-454. doi: 10.1016/S1473-3099(19)30634-6 |