2008 Journal Article Alphavirus replicon particles are highly immunogenic in the murine malaria model by homologous or heterologous immunizationDobano, C., Weiss, W. R., Kamrud, K. I., Chulay, J. D., Smith, J., Carucci, D. J. and Doolan, D. L. (2008). Alphavirus replicon particles are highly immunogenic in the murine malaria model by homologous or heterologous immunization. The Open Vaccine Journal, 1, 27-37. |
2008 Journal Article Transcriptionally active PCR for antigen identification and vaccine development: In vitro genome-wide screening and in vivo immunogenicityRegis, David P., Dobaño, Carlota, Quiñones-Olson, Paola, Liang, Xiaowu, Graber, Norma L., Stefaniak, Maureen E., Campo, Joseph J., Carucci, Daniel J., Roth, David A., He, Huaping, Felgner, Philip L. and Doolan, Denise L. (2008). Transcriptionally active PCR for antigen identification and vaccine development: In vitro genome-wide screening and in vivo immunogenicity. Molecular and Biochemical Parasitology, 158 (1), 32-45. doi: 10.1016/j.molbiopara.2007.11.009 |
2007 Journal Article Status of malaria vaccine R&D in 2007Doolan, Denise L. and Stewart, V. Ann (2007). Status of malaria vaccine R&D in 2007. Expert Review of Vaccines, 6 (6), 903-905. doi: 10.1586/14760584.6.6.903 |
2007 Journal Article Induction of multi-antigen multi-stage immune responses against Plasmodium falciparum in rhesus monkeys, in the absence of antigen interference, with heterologous DNA prime/poxvirus boost immunizationJiang, George, Charoenvit, Yupin, Moreno, Alberto, Baraceros, Maria F., Banania, Glenna, Richie, Nancy, Abot, Steve, Ganeshan, Harini, Fallarme, Victoria, Patterson, Noelle B., Geall, Andrew, Weiss, Walter R., Strobert, Elizabeth, Caro-Aquilar, Ivette, Lanar, David E., Saul, Allan, Martin, Laura B., Gowda, Kalpana, Morrissette, Craig R., Kaslow, David C., Carucci, Daniel J., Galinski, Mary R. and Doolan, Denise L. (2007). Induction of multi-antigen multi-stage immune responses against Plasmodium falciparum in rhesus monkeys, in the absence of antigen interference, with heterologous DNA prime/poxvirus boost immunization. Malaria Journal, 6 (1) 135, 135-152. doi: 10.1186/1475-2875-6-135 |
2007 Journal Article Extended immunization intervals enhance the immunogenicity and protective efficacy of plasmid DNA vaccinesBrice, Gary T., Dobano, Carlota, Sedegah, Martha, Stefaniak, Maureen, Graber, Norma L., Campo, Joseph J., Carucci, Daniel J. and Doolan, Denise L. (2007). Extended immunization intervals enhance the immunogenicity and protective efficacy of plasmid DNA vaccines. Microbes and Infection, 9 (12-13), 1439-1446. doi: 10.1016/j.micinf.2007.07.009 |
2007 Journal Article Enhancement of antibody and cellular immune responses to malaria DNA vaccines by in vivo electroporationDobano, Carlota, Widera, Georg, Rabussay, Dietmar and Doolan, Denise L. (2007). Enhancement of antibody and cellular immune responses to malaria DNA vaccines by in vivo electroporation. Vaccine, 25 (36), 6635-6645. doi: 10.1016/j.vaccine.2007.06.036 |
2007 Journal Article Targeting antigen to MHC Class I and Class II antigen presentation pathways for malaria DNA vaccinesDobañoa, Carlota, Rogersa, William O., Gowdaa , Kalpana and Doolana, Denise L. (2007). Targeting antigen to MHC Class I and Class II antigen presentation pathways for malaria DNA vaccines. Immunology Letters, 111 (2), 92-102. doi: 10.1016/j.imlet.2007.05.007 |
2007 Journal Article Viral vectors for malaria vaccine developmentLi, Shengqiang, Locke, Emily, Bruder, Joseph, Clarke, David, Doolan, Denise L., Havenga, Menzo J. E., Hill, Adrian V. S., Liljestrom, Peter, Monath, Thomas P., Naimi, Hussein Y., Ockenhouse, Christian, Tang, De-chu C., Van Kampen, Kent R., Viret, Jean-Francois, Zavala, Fidel and Dubovsky, Filip (2007). Viral vectors for malaria vaccine development. Vaccine, 25 (14), 2567-2574. doi: 10.1016/j.vaccine.2006.07.035 |
2007 Journal Article Mutating the Anchor Residues Associated with MHC Binding Inhibits and Deviates CD8+ T cell Mediated Protective Immunity Against MalariaDobano, C., McTague, A., Sette, A., Hoffman, S. L., Rogers, W. O. and Doolan, D. L. (2007). Mutating the Anchor Residues Associated with MHC Binding Inhibits and Deviates CD8+ T cell Mediated Protective Immunity Against Malaria. Molecular Immunology, 44 (9), 2235-2248. doi: 10.1016/j.molimm.2006.11.003 |
2007 Journal Article Identification of minimal CD8+ and CD4+ T cell epitopes in the Plasmodium yoelii hepatocyte erythrocyte protein 17 kDaDobano, C. and Doolan, D.L. (2007). Identification of minimal CD8+ and CD4+ T cell epitopes in the Plasmodium yoelii hepatocyte erythrocyte protein 17 kDa. Molecular Immunology, 44 (11), 3037-3048. doi: 10.1016/j.molimm.2007.01.001 |
2007 Journal Article Malaria's journey through the lymph nodeGood, Michael F. and Doolan, Denise L. (2007). Malaria's journey through the lymph node. Nature Medicine, 13 (9), 1023-1024. doi: 10.1038/nm0907-1015 |
2006 Journal Article Vaxfectin™ enhances immunogenicity and protective efficacy of P. yoelii circumsporozoite DNA vaccineSedegah, Martha, Rogers, William O., Belmonte, Arnel, Belmonte, Maria, Banania, Glenna, Patterson, Noelle, Ferrari, Marilyn, Kaslow, David C., Carucci, Daniel J., Richie, Thomas L. and Doolan, Denise L. (2006). Vaxfectin™ enhances immunogenicity and protective efficacy of P. yoelii circumsporozoite DNA vaccine. Vaccine, 24 (11), 1921-1927. doi: 10.1016/j.vaccine.2005.10.041 |
2006 Journal Article The US capitol bioterrorism anthrax exposures: Clinical epidemiological and immunological characteristicsDoolan, Denise L., Freilich, Daniel A., Brice, Gary T., Burgess, Timothy H., Berzins, Mara P., Bull, Robert L., Graber, Norma L., Dabbs, Jason L., Shatney, Lori L., Blazes, David L., Bebris, Lolita M., Malone, Maria F., Eisold, John F., Mateczun, Alfred J. and Martin, Gregory J. (2006). The US capitol bioterrorism anthrax exposures: Clinical epidemiological and immunological characteristics. Journal of Infectious Diseases, 195 (2), 174-184. doi: 10.1086/510312 |
2006 Journal Article Immune response to pre-erythrocytic stages of malaria parasitesDoolan, D. L. and Martinez-Alier, N. (2006). Immune response to pre-erythrocytic stages of malaria parasites. Current Molecular Medicine, 6 (2), 169-185. doi: 10.2174/156652406776055249 |
2006 Journal Article Identification of humoral immune responses in protein microarrays using DNA microarray data analysis techniquesSundaresh, S., Doolan, D. L., Hirst, S., Mu, Y., Unal, B., Davies, H., Felgner, P. and Baldi, P. (2006). Identification of humoral immune responses in protein microarrays using DNA microarray data analysis techniques. Bioinformatics, 22 (14), 1760-1766. doi: 10.1093/bioinformatics/btl162 |
2004 Journal Article A Small Peptide (CEL-1000) Derived from the ß-Chain of the Human Major Histocompatibility Complex Class II Molecule Induces Complete Protection against Malaria in an Antigen-Independent MannerCharoenvit, Yupin, Brice, Gary T., Bacon, David, Majam, Victoria, Williams, Jackie, Abot, Esteban, Ganeshan, Harini, Sedegah, Martha, Doolan, Denise L., Carucci, Daniel J. and Zimmerman, Daniel H. (2004). A Small Peptide (CEL-1000) Derived from the ß-Chain of the Human Major Histocompatibility Complex Class II Molecule Induces Complete Protection against Malaria in an Antigen-Independent Manner. Antimicrobial agents and chemotherapy, 48 (7), 2455-2463. doi: 10.1128/AAC.48.7.2455-2463.2004 |
2004 Journal Article Induction in Humans of CD8+ and CD4+ T Cell and Antibody Responses by Sequential Immunization with Malaria DNA and Recombinant ProteinWang, Ruobing, Epstein, Judith, Charoenvit, Yupin, Baraceros, Fe Maria, Rahardjo, Nancy, Gay, Tanya, Banania, Jo-Glenna, Chattopadhyay, Rana, de la Vega, Patricia, Richie, Thomas L., Tornieporth, Nadia, Doolan, Denise L., Kester, Kent E., Heppner, D. Gray, Norman, Jon, Carucci, Daniel J., Cohen, Joe D. and Hoffman, Stephen L. (2004). Induction in Humans of CD8+ and CD4+ T Cell and Antibody Responses by Sequential Immunization with Malaria DNA and Recombinant Protein. Journal of immunology, 172 (9), 5561-5569. doi: 10.4049/jimmunol.172.9.5561 |
2003 Journal Article Utilization of genomic sequence information to develop malaria vaccinesDoolan, D. L., Aguiar, J. C., Weiss, W. R., Sette, A., Felgner, P. L., Regis, D. P., Quinones-Casas, P., Yates, J. R. III, Blair, P. L., Richie, T. L., Hoffman, S. L. and Carucci, D. J. (2003). Utilization of genomic sequence information to develop malaria vaccines. Journal of experimental biology, 206 (21), 3789-3802. doi: 10.1242/jeb.00615 |
2003 Journal Article Identification of plasmodium falciparum antigens by antigenic analysis of genomic and proteomic dataDoolan, Denise, Southwood, S., Freilich, D. A., Sidney, J., Graber, N. L., Shatney, L., Bebris, L., Florens, L., Dobano, C., Witney, A.A., Apella, E., Hoffman, S. L., Yates, J. R. 3rd, Carucci, D. J. and Sette, A. (2003). Identification of plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data. Proceedings of the National Academy of Sciences of the United States of America, 100 (17), 9952-9957. doi: 10.1073/pnas.1633254100 |
2002 Journal Article Optimal induction of antigen-specific CD8+ T cell responses requires bystander cell participationBrice, Gary T., Graber, Norma L., Carucci, Daniel J. and Doolan, Denise L. (2002). Optimal induction of antigen-specific CD8+ T cell responses requires bystander cell participation. Journal of leukocyte biology, 72 (6), 1164-1171. doi: 10.1189/jlb.72.6.1164 |