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2002

Journal Article

Erratum: Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice (Infection and Immunity (2001) 69:3 (1643-1649))

Gramzinski, Robert A., Doolan, Denise L., Sedegah, Martha, Davis, Heather L., Krieg, Arthur M. and Hoffman, Stephen L. (2002). Erratum: Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice (Infection and Immunity (2001) 69:3 (1643-1649)). Infection and Immunity, 70 (9). doi: 10.1128/IAI.70.9.5338.2002

Erratum: Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice (Infection and Immunity (2001) 69:3 (1643-1649))

2002

Journal Article

Persistence of Protective Immunity to Malaria Induced by DNA Priming and Poxvirus Boosting: Characterization of Effector and Memory CD8+-T-Cell Populations

Sedegah, Martha, Brice, Gary T., Rogers, William O., Doolan, Denise L., Charoenvit, Yupin, Jones, Trevor R., Majam, Victoria F., Belmonte, Arnel, Lu, Minh, Belmonte, Maria, Carucci, Daniel J. and Hoffman, Stephen L. (2002). Persistence of Protective Immunity to Malaria Induced by DNA Priming and Poxvirus Boosting: Characterization of Effector and Memory CD8+-T-Cell Populations. Infection and immunity, 70 (7), 3493-3499. doi: 10.1128/IAI.70.7.3493-3499.2002

Persistence of Protective Immunity to Malaria Induced by DNA Priming and Poxvirus Boosting: Characterization of Effector and Memory CD8+-T-Cell Populations

2002

Journal Article

Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites

Hoffman, Stephen L., Goh, Lucy M. L., Luke, Thomas C., Schneider, Imogene, Le, Thong P., Doolan, Denise L., Sacci, John, De la Vega, Patricia, Dowler, Megan, Paul, Chris, Gordon, Daniel M., Stoute, Jose A., Preston Church, L. W., Sedegah, Martha, Gray Heppner, D., Ripley Ballou, W. and Richie, Thomas L. (2002). Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites. Journal of Infectious Diseases, 185 (8), 1155-1164. doi: 10.1086/339409

Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites

2002

Journal Article

Nucleic acid vaccines against malaria

Doolan, Denise L. and Hoffman, Stephen L. (2002). Nucleic acid vaccines against malaria. Chemical Immunology, 80, 308-321. doi: 10.1159/000058851

Nucleic acid vaccines against malaria

2002

Journal Article

A simple method for delivery and antigen presentation of a malaria protein in human dendritic cells (Application Note)

Doolan, Denise L. and Graber, Norma L. (2002). A simple method for delivery and antigen presentation of a malaria protein in human dendritic cells (Application Note). Delivery, 22, 6-7.

A simple method for delivery and antigen presentation of a malaria protein in human dendritic cells (Application Note)

2001

Journal Article

Foreword--MBP thematic issue on genomics

Doolan, D. L., Coppel, R. L. and Waters, A. P. (2001). Foreword--MBP thematic issue on genomics. Molecular and Biochemical Parasitology, 118 (2), 127-8. doi: 10.1016/s0166-6851(01)00389-9

Foreword--MBP thematic issue on genomics

2001

Journal Article

Determining liver stage parasite burden by real time quantitative PCR as a method for evaluating pre-erythrocytic malaria vaccine efficacy

Witney, Adam A., Doolan, Denise L., Anthony, Robert M., Weiss, Walter R., Hoffman, Stephen L. and Carucci, Daniel J. (2001). Determining liver stage parasite burden by real time quantitative PCR as a method for evaluating pre-erythrocytic malaria vaccine efficacy. Molecular and Biochemical Parasitology, 118 (2), 233-245. doi: 10.1016/S0166-6851(01)00372-3

Determining liver stage parasite burden by real time quantitative PCR as a method for evaluating pre-erythrocytic malaria vaccine efficacy

2001

Journal Article

Expression of the chemokine MIG is a sensitive and predictive marker for antigen-specific, genetically restricted IFN-γ production and IFN-γ-secreting cells

Brice, G. T., Graber, N. L., Hoffman, S. L. and Doolan, D. L. (2001). Expression of the chemokine MIG is a sensitive and predictive marker for antigen-specific, genetically restricted IFN-γ production and IFN-γ-secreting cells. Journal of Immunological Methods, 257 (1-2), 55-69. doi: 10.1016/s0022-1759(01)00446-x

Expression of the chemokine MIG is a sensitive and predictive marker for antigen-specific, genetically restricted IFN-γ production and IFN-γ-secreting cells

2001

Journal Article

Induction of CD4+ T cell-dependent CD8+ type 1 responses in humans by a malaria DNA vaccine

Wang, Ruobing, Epstein, Judith, Baraceros, Fe Maria, Gorak, Edward J., Charoenvit, Yupin, Carucci, Daniel J., Hedstrom, Richard C., Rahardjo, Nancy, Gay, Tanya, Hobart, Peter, Stout, Rick, Jones, Trevor R., Richie, Thomas L., Parker, Suezanne E., Doolan, Denise L., Norman, Jon and Hoffman, Stephen L. (2001). Induction of CD4+ T cell-dependent CD8+ type 1 responses in humans by a malaria DNA vaccine. Proceedings of the National Academy of Sciences of the United States of America, 98 (19), 10817-10822. doi: 10.1073/pnas.181123498

Induction of CD4+ T cell-dependent CD8+ type 1 responses in humans by a malaria DNA vaccine

2001

Journal Article

DNA-based vaccines against malaria: Status and promise of the Multi-Stage Malaria DNA Vaccine Operation

Doolan, Denise L and Hoffman, Stephen L (2001). DNA-based vaccines against malaria: Status and promise of the Multi-Stage Malaria DNA Vaccine Operation. International Journal for Parasitology, 31 (8), 753-762. doi: 10.1016/S0020-7519(01)00184-9

DNA-based vaccines against malaria: Status and promise of the Multi-Stage Malaria DNA Vaccine Operation

2001

Journal Article

Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice

Gramzinski, R. A., Doolan, D. L., Sedegah, M., Davis, H. L., Krieg, A. M. and Hoffman, S. L. (2001). Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice. Infection and Immunity, 69 (3), 1643-1649. doi: 10.1128/IAI.69.3.1643-1649.2001

Interleukin-12- and gamma interferon-dependent protection against malaria conferred by CpG oligodeoxynucleotide in mice

2000

Journal Article

Malaria vaccines-targeting infected hepatocytes

Hoffman, Stephen L. and Doolan, Denise L. (2000). Malaria vaccines-targeting infected hepatocytes. Nature Medicine, 6 (11), 1218-1219. doi: 10.1038/81315

Malaria vaccines-targeting infected hepatocytes

2000

Journal Article

HLA degenerate T-cell epitopes from Plasmodium falciparum liver stage-specific antigen 1 (LSA-1) are highly conserved in isolates from geographically distinct areas

Ravichandran, M., Doolan, D. L., Cox-Singh, J., Hoffman, S. L. and Singh, B. (2000). HLA degenerate T-cell epitopes from Plasmodium falciparum liver stage-specific antigen 1 (LSA-1) are highly conserved in isolates from geographically distinct areas. Parasite Immunology, 22 (9), 469-473. doi: 10.1046/j.1365-3024.2000.00324.x

HLA degenerate T-cell epitopes from Plasmodium falciparum liver stage-specific antigen 1 (LSA-1) are highly conserved in isolates from geographically distinct areas

2000

Journal Article

The complexity of protective immunity against liver-stage malaria

Doolan, Denise L. and Hoffman, Stephen L. (2000). The complexity of protective immunity against liver-stage malaria. Journal of Immunology, 165 (3), 1453-1462. doi: 10.4049/jimmunol.165.3.1453

The complexity of protective immunity against liver-stage malaria

2000

Journal Article

HLA-DR-promiscuous T cell epitopes frown Plasmodium falciparum pre- erythrocytic-stage antigens restricted by multiple HLA class II alleles

Doolan, Denise L., Southwood, Scott, Chesnut, Robert, Appella, Ettore, Gomez, Eduardo, Richards, Allen, Higashimoto, Yuichiro I., Maewal, Ajesh, Sidney, John, Gramzinski, Robert A., Mason, Carl, Koech, Davy, Hoffman, Stephen L. and Sette, Alessandro (2000). HLA-DR-promiscuous T cell epitopes frown Plasmodium falciparum pre- erythrocytic-stage antigens restricted by multiple HLA class II alleles. Journal of Immunology, 165 (2), 1123-1137. doi: 10.4049/jimmunol.165.2.1123

HLA-DR-promiscuous T cell epitopes frown Plasmodium falciparum pre- erythrocytic-stage antigens restricted by multiple HLA class II alleles

2000

Journal Article

Safety, tolerability and humoral immune responses after intramuscular administration of a malaria DNA vaccine to healthy adult volunteers

Le, T. P., Coonan, K. M., Hedstrom, R. C., Charoenvit, Y., Sedegah, M., Epstein, J. E., Kumar, S., Wang, R., Doolan, D. L., Maguire, J. D., Parker, S. E., Hobart, P., Norman, J. and Hoffman, S. L. (2000). Safety, tolerability and humoral immune responses after intramuscular administration of a malaria DNA vaccine to healthy adult volunteers. Vaccine, 18 (18), 1893-1901. doi: 10.1016/s0264-410x(99)00407-7

Safety, tolerability and humoral immune responses after intramuscular administration of a malaria DNA vaccine to healthy adult volunteers

2000

Journal Article

Can malaria DNA vaccines on their own be as immunogenic and protective as prime-boost approaches to immunization?

Hoffman, S. L. and Doolan, D. L. (2000). Can malaria DNA vaccines on their own be as immunogenic and protective as prime-boost approaches to immunization?. Developments in biologicals, 104, 121-132.

Can malaria DNA vaccines on their own be as immunogenic and protective as prime-boost approaches to immunization?

1999

Journal Article

IL-12 and NK cells are required for antigen-specific adaptive immunity against malaria initiated by CD8+ T cells in the Plasmodium yoelii model

Doolan, Denise L. and Hoffman, Stephen L. (1999). IL-12 and NK cells are required for antigen-specific adaptive immunity against malaria initiated by CD8+ T cells in the Plasmodium yoelii model. Journal of Immunology, 163 (2), 884-892.

IL-12 and NK cells are required for antigen-specific adaptive immunity against malaria initiated by CD8+ T cells in the Plasmodium yoelii model

1999

Journal Article

CD4+ T-cell- and gamma interferon-dependent protection against murine malaria by immunization with linear synthetic peptides from a Plasmodium yoelii 17-kilodalton hepatocyte erythrocyte protein

Charoenvit, Yupin, Majam, Victoria Fallarme, Corradin, Giampietro, Sacci Jr., John B., Wang, Ruobing, Doolan, Denise L., Jones, Trevor R., Abot, Esteban, Patarroyo, Manuel E., Guzman, Fanny and Hoffman, Stephen L. (1999). CD4+ T-cell- and gamma interferon-dependent protection against murine malaria by immunization with linear synthetic peptides from a Plasmodium yoelii 17-kilodalton hepatocyte erythrocyte protein. Infection and Immunity, 67 (11), 5604-5614. doi: 10.1128/iai.67.11.5604-5614.1999

CD4+ T-cell- and gamma interferon-dependent protection against murine malaria by immunization with linear synthetic peptides from a Plasmodium yoelii 17-kilodalton hepatocyte erythrocyte protein

1999

Journal Article

Immune effector mechanisms in malaria

Good, Michael F. and Doolan, Denise L. (1999). Immune effector mechanisms in malaria. Current Opinion in Immunology, 11 (4), 412-419. doi: 10.1016/S0952-7915(99)80069-7

Immune effector mechanisms in malaria