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2012 Journal Article gamma delta T cells augment rejection of skin grafts by enhancing cross-priming of CD8 T cells to skin-derived antigenRahimpour, Azad, Mattarollo, Stephen R., Yong, Michelle, Leggatt, Graham R., Steptoe, Raymond J. and Frazer, Ian H. (2012). gamma delta T cells augment rejection of skin grafts by enhancing cross-priming of CD8 T cells to skin-derived antigen. Journal of Investigative Dermatology, 132 (6), 1656-1664. doi: 10.1038/jid.2012.16 |
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2012 Journal Article Histone deacetylase inhibitors in the generation of the anti-tumour immune responseLeggatt, Graham R. and Gabrielli, Brian (2012). Histone deacetylase inhibitors in the generation of the anti-tumour immune response. Immunology and Cell Biology, 90 (1), 33-38. doi: 10.1038/icb.2011.94 |
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2012 Journal Article Role of intratumoural heterogeneity in cancer drug resistance: Molecular and clinical perspectivesSaunders, Nicholas A., Simpson, Fiona, Thompson, Erik W., Hill, Michelle M., Endo-Munoz, Liliana, Leggatt, Graham, Minchin, Rodney F. and Guminski, Alexander (2012). Role of intratumoural heterogeneity in cancer drug resistance: Molecular and clinical perspectives. EMBO Molecular Medicine, 4 (8), 675-684. doi: 10.1002/emmm.201101131 |
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2011 Journal Article NKT cells inhibit antigen-specific effector CD8 T cell induction to skin viral proteinsMattarollo, Stephen R., Yong, Michelle, Gosmann, Christina, Choyce, Allison, Chan, Dora, Leggatt, Graham R. and Frazer, Ian H. (2011). NKT cells inhibit antigen-specific effector CD8 T cell induction to skin viral proteins. Journal of Immunology, 187 (4), 1601-1608. doi: 10.4049/jimmunol.1100756 |
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2011 Journal Article Prevention and treatment of papillomavirus-related cancers through immunizationFrazer, Ian H., Leggatt, Graham R. and Mattarollo, Stephen R. (2011). Prevention and treatment of papillomavirus-related cancers through immunization. Annual Review of Immunology, 29, 111-138. doi: 10.1146/annurev-immunol-031210-101308 |
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2011 Journal Article Human papillomavirus 16 E7 protein inhibits interferon-gamma-mediated enhancement of keratinocyte antigen processing and T-cell lysisZhou, Fang, Leggatt, Graham R. and Frazer, Ian H. (2011). Human papillomavirus 16 E7 protein inhibits interferon-gamma-mediated enhancement of keratinocyte antigen processing and T-cell lysis. The Federation of European Biochemical Societies (FEBS) Journal, 278 (6), 955-963. doi: 10.1111/j.1742-4658.2011.08011.x |
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2011 Journal Article Regulation of immune responses to HPVinfection and during HPV-directed immunotherapyBhat, Purnima, Mattarollo, Stephen R., Gosmann, Christina, Frazer, Ian H. and Leggatt, Graham R. (2011). Regulation of immune responses to HPVinfection and during HPV-directed immunotherapy. Immunological Reviews, 239 (1), 85-98. doi: 10.1111/j.1600-065X.2010.00966.x |
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2010 Journal Article IL-1 signalling determines the fate of skin grafts expressing non-self protein in keratinocytesHadis, Usriansyah, Leggatt, Graham R., Thomas, Ranjeny, Frazer, Ian H. and Kovacs, Eva M. (2010). IL-1 signalling determines the fate of skin grafts expressing non-self protein in keratinocytes. Experimental Dermatology, 19 (8), 723-729. doi: 10.1111/j.1600-0625.2010.01092.x |
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2010 Journal Article Antigen-specific CD4 cells assist CD8 T-effector cells in eliminating keratinocytesBroom, Jennifer K., Lew, Andrew M., Azukizawa, Hiroaki, Kenna, Tony J., Leggatt, Graham R. and Frazer, Ian H. (2010). Antigen-specific CD4 cells assist CD8 T-effector cells in eliminating keratinocytes. Journal of Investigative Dermatology, 130 (6), 1581-1589. doi: 10.1038/jid.2010.17 |
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2010 Journal Article Secretion of IFN-gamma but not IL-17 by CD1d-restricted NKT cells enhances rejection of skin grafts expressing epithelial cell-derived antigenMattarollo, Stephen R., Yong, Michelle, Tan, Lieven, Frazer, Ian H. and Leggatt, Graham R. (2010). Secretion of IFN-gamma but not IL-17 by CD1d-restricted NKT cells enhances rejection of skin grafts expressing epithelial cell-derived antigen. Journal of Immunology, 184 (10), 5663-5669. doi: 10.4049/jimmunol.0903730 |
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2010 Journal Article Invariant NKT Cells in Hyperplastic Skin Induce a Local Immune Suppressive Environment by IFN-gamma ProductionMattarollo, Stephen R., Rahimpour, Azad, Choyce, Allison, Godfrey, Dale I., Leggatt, Graham R. and Frazer, Ian H. (2010). Invariant NKT Cells in Hyperplastic Skin Induce a Local Immune Suppressive Environment by IFN-gamma Production. Journal of Immunology, 184 (3), 1242-1250. doi: 10.4049/jimmunol.0902191 |
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2009 Journal Article Keratinocytes efficiently process endogenous antigens for cytotoxic T-cell mediated lysisZhou, F, Frazer, IH and Leggatt, GR (2009). Keratinocytes efficiently process endogenous antigens for cytotoxic T-cell mediated lysis. EXPERIMENTAL DERMATOLOGY, 18 (12), 1053-1059. doi: 10.1111/j.1600-0625.2009.00907.x |
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2009 Journal Article Enhanced tumor growth in the NaS1 sulfate transporter null mouseDawson, P A, Choyce, A, Chuang, C, Whitelock, J, Markovich, D and Leggatt, GR (2009). Enhanced tumor growth in the NaS1 sulfate transporter null mouse. Cancer Science, 101 (2), 369-373. doi: 10.1111/j.1349-7006.2009.01399.x |
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2009 Journal Article IFN-gamma promotes generation of IL-10 secreting CD4+ T cells that suppress generation of CD8 responses in an antigen-experienced hostLiu, Xiao Song, Leerberg, Joanne, MacDonald, Kelli, Leggatt, Graham and Frazer, Ian (2009). IFN-gamma promotes generation of IL-10 secreting CD4+ T cells that suppress generation of CD8 responses in an antigen-experienced host. The Jounral of Immunology, 183 (1), 51-58. doi: 10.4049/jimmunol.0802047 |
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2009 Journal Article Both treated and untreated tumors are eliminated by short hairpin RNA-based induction of target-specific immune responsesGu, Wenyi, Cochrane, Melanie, Leggatt, Graham, Payne, Elizabeth, Choyce, Allison, Zhou, Fang, Tindle, Robert and McMillan, Nigel (2009). Both treated and untreated tumors are eliminated by short hairpin RNA-based induction of target-specific immune responses. Proceedings of the National Academy of Sciences of the United States of America, 106 (20), 8314-8319. doi: 10.1073/pnas.0812085106 |
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2009 Journal Article Epithelial expression of human papillomavirus type 16 E7 protein results in peripheral CD8 T-cell suppression mediated by CD4(+)CD25(+) T cellsNarayan, S., Choyce, A., Linedale, R., Saunders, N. A., Dahler, A., Chan, E., Fernando, G. J., Frazer, I. H. and Leggatt, G. R. (2009). Epithelial expression of human papillomavirus type 16 E7 protein results in peripheral CD8 T-cell suppression mediated by CD4(+)CD25(+) T cells. European Journal of Immunology, 39 (2), 481-490. doi: 10.1002/eji.200838527 |
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2008 Journal Article TLR7 stimulation augments T effector-mediated rejection, of skin expressing neo-self antigen in keratinocytesZhong, Jie, Usriansyah Usriansyah, Rachel De Kluyver, Leggatt, Graham R., Fernando, Germain J. and Frazer, Ian H. (2008). TLR7 stimulation augments T effector-mediated rejection, of skin expressing neo-self antigen in keratinocytes. European Journal of Immunology, 38 (1), 73-81. doi: 10.1002/eji.200737599 |
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2007 Journal Article HPV vaccines: the beginning of the end for cervical cancerLeggatt, G. R. and Frazer, I. H. (2007). HPV vaccines: the beginning of the end for cervical cancer. Current Opinion In Immunology, 19 (2), 232-238. doi: 10.1016/j.coi.2007.01.004 |
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2007 Journal Article Secondary immunisation with high-dose heterologous peptide leads to CD8 T cell populations with reduced functional avidityNarayan, S., Choyce, A., Fernando, G. J. P. and Leggatt, G. R. (2007). Secondary immunisation with high-dose heterologous peptide leads to CD8 T cell populations with reduced functional avidity. European Journal of Immunology, 37 (2), 406-415. doi: 10.1002/eji.200535688 |
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2006 Journal Article Inhibition of cervical cancer cell growth in vitro and in vivo with lentiviral-vector delivered short hairpin RNA targeting human papillomavirus E6 and E7 oncogenesGu, W., Putral, L., Hengst, K., Minto, K., Saunders, N. A., Leggatt, G. and McMillan, N. A. J. (2006). Inhibition of cervical cancer cell growth in vitro and in vivo with lentiviral-vector delivered short hairpin RNA targeting human papillomavirus E6 and E7 oncogenes. Cancer Gene Therapy, 13 (11), 1023-1032. doi: 10.1038/sj.cgt.7700971 |
