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2015

Journal Article

Corrigendum: a stress-induced early innate response causes multidrug tolerance in melanoma (vol 34, pg 4448, 2015)

Menon, D. Ravindran, Das, S., Krepler, C., Vultur, A., Rinner, B., Schauer, S., Kashofer, K., Wagner, K., Zhang, G., Rad, E. Bonyadi, Haass, N. K., Soyer, H. P., Gabrielli, B., Somasundaram, R., Hoefler, G., Herlyn, M. and Schaider, H. (2015). Corrigendum: a stress-induced early innate response causes multidrug tolerance in melanoma (vol 34, pg 4448, 2015). Oncogene, 34 (34), 4545-4545. doi: 10.1038/onc.2014.432

Corrigendum: a stress-induced early innate response causes multidrug tolerance in melanoma (vol 34, pg 4448, 2015)

2015

Journal Article

JIP4 is a PLK1 binding protein that regulates p38MAPK activity in G2 phase

Pinder, Alex, Loo, Dorothy, Harrington, Brittney, Oakes, Vanessa, Hill, Michelle M. and Gabrielli, Brian (2015). JIP4 is a PLK1 binding protein that regulates p38MAPK activity in G2 phase. Cellular Signalling, 27 (11), 2296-2303. doi: 10.1016/j.cellsig.2015.08.009

JIP4 is a PLK1 binding protein that regulates p38MAPK activity in G2 phase

2014

Journal Article

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration

Irvine, Katharine M., Skoien, Richard, Bokil, Nilesh J., Melino, Michelle, Thomas, Gethin P., Loo, Dorothy, Gabrielli, Brian, Hill, Michelle M., Sweet, Matthew J., Clouston, Andrew D. and Powell, Elizabeth E. (2014). Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration. World Journal of Gastroenterology, 20 (47), 17851-17862. doi: 10.3748/wjg.v20.i47.17851

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration

2014

Journal Article

DCT protects human melanocytic cells from UVR and ROS damage and increases cell viability

Ainger, Stephen A., Yong, Xuan L., Wong, Shu S., Skalamera, Dubravka, Gabrielli, Brian, Leonard, J. Helen and Sturm, Richard A. (2014). DCT protects human melanocytic cells from UVR and ROS damage and increases cell viability. Experimental Dermatology, 23 (12), 916-921. doi: 10.1111/exd.12574

DCT protects human melanocytic cells from UVR and ROS damage and increases cell viability

2014

Journal Article

Cyclin A/Cdk2 regulates Cdh1 and claspin during late S/G2 phase of the cell cycle

Oakes, Vanessa, Wang, Weili, Harrington, Brittney, Lee, Won Jae, Beamish, Heather, Chia, Kee Ming, Pinder, Alex, Goto, Hidemasa, Inagaki, Masaki, Pavey, Sandra and Gabrielli, Brian (2014). Cyclin A/Cdk2 regulates Cdh1 and claspin during late S/G2 phase of the cell cycle. Cell Cycle, 13 (20), 3302-3311. doi: 10.4161/15384101.2014.949111

Cyclin A/Cdk2 regulates Cdh1 and claspin during late S/G2 phase of the cell cycle

2014

Journal Article

Decatenation checkpoint defective melanomas are dependent on PI3K for survival

Brooks, Kelly, Ranall, Max, Spoerri, Loredana, Stevenson, Alex, Gunasingh, Gency, Pavey, Sandra, Meunier, Fred, Gonda, Thomas J. and Gabrielli, Brian (2014). Decatenation checkpoint defective melanomas are dependent on PI3K for survival. Pigment Cell and Melanoma Research, 27 (5), 813-821. doi: 10.1111/pcmr.12268

Decatenation checkpoint defective melanomas are dependent on PI3K for survival

2014

Journal Article

Rapid mapping of interactions between human SNX-BAR proteins measured in vitro by AlphaScreen and single-molecule spectroscopy

Sierecki, Emma, Stevers, Loes M., Giles, Nichole, Polinkovsky, Mark E., Moustaqil, Mehdi, Mureev, Sergey, Johnston, Wayne A., Dahmer-Heath, Mareike, Skalamera, Duka, Gonda, Thomas J., Gabrielli, Brian, Collins, Brett M., Alexandrov, Kirill and Gambin, Yann (2014). Rapid mapping of interactions between human SNX-BAR proteins measured in vitro by AlphaScreen and single-molecule spectroscopy. Molecular and Cellular Proteomics, 13 (9), 2233-2245. doi: 10.1074/mcp.M113.037275

Rapid mapping of interactions between human SNX-BAR proteins measured in vitro by AlphaScreen and single-molecule spectroscopy

2014

Journal Article

Phenotypic characterization of nevus and tumor patterns in MITF E318K mutation carrier melanoma patients

Sturm, Richard A., Fox, Carly, McClenahan, Phil, Jagirdar, Kasturee, Ibarrola-Villava, Maider, Banan, Parastoo, Abbott, Nicola C., Ribas, Gloria, Gabrielli, Brian, Duffy, David L. and Soyer, H. Peter (2014). Phenotypic characterization of nevus and tumor patterns in MITF E318K mutation carrier melanoma patients. Journal of Investigative Dermatology, 134 (1), 141-149. doi: 10.1038/jid.2013.272

Phenotypic characterization of nevus and tumor patterns in MITF E318K mutation carrier melanoma patients

2013

Journal Article

DNA repair and cell cycle checkpoint defects as drivers and therapeutic targets in melanoma.

Pavey, Sandra, Spoerri, Loredana, Haass, Nikolas K. and Gabrielli, Brian (2013). DNA repair and cell cycle checkpoint defects as drivers and therapeutic targets in melanoma.. Pigment Cell and Melanoma Research, 26 (6), 805-816. doi: 10.1111/pcmr.12136

DNA repair and cell cycle checkpoint defects as drivers and therapeutic targets in melanoma.

2013

Journal Article

CDC25B overexpression stabilises centrin 2 and promotes the formation of excess centriolar foci

Boutros, Rose, Mondesert, Odile, Lorenzo, Corinne, Astuti, Puji, McArthur, Grant, Chircop, Megan, Ducommun, Bernard and Gabrielli, Brian (2013). CDC25B overexpression stabilises centrin 2 and promotes the formation of excess centriolar foci. PLoS One, 8 (7) e67822, e67822.1-e67822.13. doi: 10.1371/journal.pone.0067822

CDC25B overexpression stabilises centrin 2 and promotes the formation of excess centriolar foci

2013

Journal Article

Defective decatenation checkpoint function is a common feature of melanoma

Brooks, Kelly, Chia, Kee Ming, Spoerri, Loredana, Mukhopadhyay, Pamela, Wigan, Matthew, Stark, Mitchell, Pavey, Sandra and Gabrielli, Brian (2013). Defective decatenation checkpoint function is a common feature of melanoma. Journal of Investigative Dermatology, 134 (1), 150-158. doi: 10.1038/jid.2013.264

Defective decatenation checkpoint function is a common feature of melanoma

2013

Journal Article

Oxidative stress and cell senescence combine to cause maximal renal Tubular Epithelial Cell Dysfunction and loss in an in vitro Model of Kidney Disease

Small, David M., Bennett, Nigel C., Roy, Sandrine, Gabrielli, Brian G., Johnson, David W. and Gobe, Glenda C. (2013). Oxidative stress and cell senescence combine to cause maximal renal Tubular Epithelial Cell Dysfunction and loss in an in vitro Model of Kidney Disease. Nephron Experimental Nephrology, 122 (3-4), 123-130. doi: 10.1159/000350726

Oxidative stress and cell senescence combine to cause maximal renal Tubular Epithelial Cell Dysfunction and loss in an in vitro Model of Kidney Disease

2013

Journal Article

Truncated MEK1 is required for transient activation of MAPK signalling in G2 phase cells

Pike, Tanya, Widberg, Charlotte, Goodall, Andrew, Payne, Elizabeth, Giles, Nichole, Hancock, John and Gabrielli, Brian (2013). Truncated MEK1 is required for transient activation of MAPK signalling in G2 phase cells. Cellular Signalling, 25 (6), 1423-1428. doi: 10.1016/j.cellsig.2013.03.014

Truncated MEK1 is required for transient activation of MAPK signalling in G2 phase cells

2013

Journal Article

Similar, not the same: diverse roles and regulation of cyclin Es

Spoerri, Loredana and Gabrielli, Brian (2013). Similar, not the same: diverse roles and regulation of cyclin Es. Cell Cycle, 12 (5), 715-715. doi: 10.4161/cc.23909

Similar, not the same: diverse roles and regulation of cyclin Es

2013

Journal Article

A potent Chk1 inhibitor is selectively cytotoxic in melanomas with high levels of replicative stress

Brooks, K., Oakes, V., Edwards, B., Ranall, M., Leo, P., Pavey, S., Pinder, A., Beamish, H., Mukhopadhyay, P., Lambie, D. and Gabrielli, B. (2013). A potent Chk1 inhibitor is selectively cytotoxic in melanomas with high levels of replicative stress. Oncogene, 32 (6), 788-796. doi: 10.1038/onc.2012.72

A potent Chk1 inhibitor is selectively cytotoxic in melanomas with high levels of replicative stress

2013

Journal Article

MicroRNA-182-5-p targets a network of genes involved in DNA repair

Krishnan, Keerthana, Steptoe, Anita L., Martin, Hilary C., Wani, Shivangi, Nones, Katia, Waddell, Nic, Mariasegaram, Mythily, Simpson, Peter T., Lakhani, Sunil R., Gabrielli, Brian, Vlassov, Alexander, Cloonan, Nicole and Grimmond, Sean M. (2013). MicroRNA-182-5-p targets a network of genes involved in DNA repair. RNA, 19 (2), 230-242. doi: 10.1261/rna.034926.112

MicroRNA-182-5-p targets a network of genes involved in DNA repair

2012

Journal Article

Generation of a genome scale lentiviral vector library for EF1α promoter-driven expression of hman ORFs and identification of human genes affecting viral titer

Skalamera, Dubravka, Dahmer, Mareike, Purdon, Amy S., Wilson, Benjamin M., Ranall, Max V., Blumenthal, Antje, Gabrielli, Brian and Gonda, Thomas J. (2012). Generation of a genome scale lentiviral vector library for EF1α promoter-driven expression of hman ORFs and identification of human genes affecting viral titer. PloS One, 7 (12) e51733, e51733.1-e51733.15. doi: 10.1371/journal.pone.0051733

Generation of a genome scale lentiviral vector library for EF1α promoter-driven expression of hman ORFs and identification of human genes affecting viral titer

2012

Journal Article

A UVR-induced G2-phase checkpoint response to ssDNA gaps produced by replication fork bypass of unrepaired lesions is defective in melanoma

Wigan, Matthew, Pinder, Alex, Giles, Nichole, Pavey, Sandra, Burgess, Andrew, Wong, ShuShyan, Sturm, Rick A. and Gabrielli, Brian (2012). A UVR-induced G2-phase checkpoint response to ssDNA gaps produced by replication fork bypass of unrepaired lesions is defective in melanoma. Journal of Investigative Dermatology, 132 (6), 1681-1688. doi: 10.1038/jid.2012.41

A UVR-induced G2-phase checkpoint response to ssDNA gaps produced by replication fork bypass of unrepaired lesions is defective in melanoma

2012

Journal Article

Keeping replicative stress in Chk

Brooks, Kelly and Gabrielli, Brian (2012). Keeping replicative stress in Chk. Cell Cycle, 11 (11), 2039-2040. doi: 10.4161/cc.20425

Keeping replicative stress in Chk

2012

Journal Article

Defective cell cycle checkpoints as targets for anti-cancer therapies

Gabrielli, Brian, Brooks, Kelly and Pavey, Sandra (2012). Defective cell cycle checkpoints as targets for anti-cancer therapies. Frontiers in Pharmacology, 3 (9) 9, 9.1-9.6. doi: 10.3389/fphar.2012.00009

Defective cell cycle checkpoints as targets for anti-cancer therapies