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2007 Journal Article Caffeine promotes apoptosis in mitotic spindle checkpoint-arrested cellsGabrielli, B., Chau, Y. Q., Giles, N., Harding, A., Stevens, F. and Beamish, H. (2007). Caffeine promotes apoptosis in mitotic spindle checkpoint-arrested cells. The Journal of Biological Chemistry, 282 (10), 6954-6964. doi: 10.1074/jbc.M610104200 |
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2006 Journal Article Inhibition of S/G(2) phase CDK4 reduces mitotic fidelityBurgess, A, Wigan, M, Giles, N, DePinto, W, Gillespie, P, Stevens, F and Gabrielli, B (2006). Inhibition of S/G(2) phase CDK4 reduces mitotic fidelity. Journal of Biological Chemistry, 281 (15), 9987-9995. doi: 10.1074/jbc.M512714200 |
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2006 Journal Article Spontaneous and UV radiation-induced multiple metastatic melanomas in Cdk4(R24C/R24C)/TPras miceHacker, E., Muller, H. K., Irwin, N., Gabrielli, B., Lincoin, D., Pavey, S., Powell, M. B., Malumbres, M., Barbacid, M., Hayward, N. and Walker, G. (2006). Spontaneous and UV radiation-induced multiple metastatic melanomas in Cdk4(R24C/R24C)/TPras mice. Cancer Research, 66 (6), 2946-2952. doi: 10.1158/0008-5472.CAN-05-3196 |
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2005 Journal Article Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesisFabbro, Megan, Zhou, Bin-Bing, Takahasi, Mikiko, Sarcevic, Boris, Lal, Preeti, Graham, Mark E., Gabrielli, Brian G., Robinson, Phillip J., Nigg, Erich A., Ono, Yoshitaka and Khanna, Kum Kum (2005). Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis. Developmental Cell, 9 (4), 477-488. doi: 10.1016/j.devcel.2005.09.003 |
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2005 Journal Article RNA interference against human papillomavirus oncogenes in cervical cancer cells results in increased sensitivity to cisplatinPutral, L. N., Bywater, M. J., Gu, W. Y., Saunders, N. A., Gabrielli, B. G., Leggatt, G. R. and McMillan, N. A. J. (2005). RNA interference against human papillomavirus oncogenes in cervical cancer cells results in increased sensitivity to cisplatin. Molecular Pharmacology, 68 (5), 1311-1319. doi: 10.1124/mol.105.014191 |
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2004 Journal Article Histone-deacetylase inhibitors for the treatment of cancerLindemann, Ralph K., Gabrielli, Brian G. and Johnstone, Ricky W. (2004). Histone-deacetylase inhibitors for the treatment of cancer. Cell Cycle, 3 (6), 779-788. doi: 10.4161/cc.3.6.927 |
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2004 Journal Article Histone deacetylase inhibitors specifically kill nonproliferating tumour cellsBurgess, Andrew, Ruefli, Astrid, Beamish, Heather, Warrener, Robyn, Saunders, Nicholas, Johnstone, Ricky and Gabrielli, Brian (2004). Histone deacetylase inhibitors specifically kill nonproliferating tumour cells. Oncogene, 23 (40), 6693-6701. doi: 10.1038/sj.onc.1207893 |
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2004 Journal Article Analysis of checkpoint responses to histone deacetylase inhibitorsBeamish, Heather, Warrener, Robyn and Gabrielli, Brian G (2004). Analysis of checkpoint responses to histone deacetylase inhibitors. Methods in molecular biology (Clifton, N.J.), 281, 245-259. doi: 10.1385/1-59259-811-0:245 |
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2004 Journal Article The EBNA- 3 gene family proteins disrupt the G2/M checkpointKrauer, Kenia G., Burgess, Andrew, Buck, Marion, Flanagan, James, Sculley, Tom B. and Gabrielli, Brian (2004). The EBNA- 3 gene family proteins disrupt the G2/M checkpoint. Oncogene, 23 (7), 1342-1353. doi: 10.1038/sj.onc.1207253 |
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2004 Journal Article Analyzing checkpoint controls in human skinPavey, S. and Gabrielli, B. G. (2004). Analyzing checkpoint controls in human skin. Methods in Molecular Biology, 280 (1), 175-183. |
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2004 Journal Article Defining the chemotherapeutic targets of Histone Deacetylase inhibitorsGabrielli, B. G., Warrener, R. M., Burgess, A. J. and Beamish, H. J. (2004). Defining the chemotherapeutic targets of Histone Deacetylase inhibitors. Annals New York Academy of Sciences, 1030, 627-635. doi: 10.1196/annals.1329.073 |
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2003 Journal Article Tumor cell-specific cytotoxicity by targeting cell cycle checkpointsWarrener, R, Beamish, H, Burgess, A, Waterhouse, NJ, Giles, N, Fairlie, DP and Gabrielli, B (2003). Tumor cell-specific cytotoxicity by targeting cell cycle checkpoints. Faseb Journal, 17 (9), 1550-1570. doi: 10.1096/fj.02-1003fje |
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2003 Journal Article Mechanism of mitosis-specific activation of MEK1Harding, A., Giles, N., Burgess, A., Hancock, J. F. and Gabrielli, B. G. (2003). Mechanism of mitosis-specific activation of MEK1. Journal of Biological Chemistry, 278 (19), 16747-16754. doi: 10.1074/jbc.M301015200 |
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2003 Journal Article 14-3-3 acts as an intramolecular bridge to regulate cdc25B localization and activityGiles, N., Forrest, A. and Gabrielli, B. (2003). 14-3-3 acts as an intramolecular bridge to regulate cdc25B localization and activity. Journal of Biological Chemistry, 278 (31), 28580-28587. doi: 10.1074/jbc.M304027200 |
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2003 Journal Article APC mutation and tumour budding in colorectal cancerJass, JR, Barker, M, Fraser, L, Walsh, MD, Whitehall, VLJ, Gabrielli, B, Young, J and Leggett, BA (2003). APC mutation and tumour budding in colorectal cancer. Journal of Clinical Pathology, 56 (1), 69-73. doi: 10.1136/jcp.56.1.69 |
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2002 Journal Article Identifying molecular targets mediating the anticancer activity of histone deacetylase inhibitors: A work in progressGabrielli, B. G., Johnstone, R. W. and Saunders, N. A. (2002). Identifying molecular targets mediating the anticancer activity of histone deacetylase inhibitors: A work in progress. Current Cancer Drug Targets, 2 (4), 337-353. doi: 10.2174/1568009023333818 |
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2002 Journal Article A histone deacetylase inhibitor, azelaic bishydroxamic acid, shows cytotoxicity on Epstein-Barr virus-transformed B-cell lines - A potential therapy for posttransplant lymphoproliferative diseaseSculley, T. B., Buck, M., Gabrielli, B., Parsons, P. G. and Krauer, K. G. (2002). A histone deacetylase inhibitor, azelaic bishydroxamic acid, shows cytotoxicity on Epstein-Barr virus-transformed B-cell lines - A potential therapy for posttransplant lymphoproliferative disease. Transplantation, 73 (2), 271-279. doi: 10.1097/00007890-200201270-00021 |
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2002 Journal Article alpha-melanocyte stimulating hormone potentiates p16/CDKN2A expression in human skin after ultraviolet irradiationPavey, S. and Gabrielli, B. (2002). alpha-melanocyte stimulating hormone potentiates p16/CDKN2A expression in human skin after ultraviolet irradiation. Cancer Research, 62 (3), 875-880. |
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2002 Journal Article Loss of p16 expression is associated with histological features of melanoma invasionPavey, S. J., Cummings, M. C., Whiteman, D. C., Castellano, M., Walsh, M. D., Gabrielli, B. G., Green, A. and Hayward, N. K. (2002). Loss of p16 expression is associated with histological features of melanoma invasion. Melanoma Research, 12 (6), 539-547. doi: 10.1097/01.cmr.0000043154.28051.9f |
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2002 Journal Article Tumor-selective toxicity of histone deacetylase inhibitors is due to their targeting cell cycle checkpoint pointsGabrielli, B, Warrener, R, Beamish, H, Burgess, A and Waterhouse, N (2002). Tumor-selective toxicity of histone deacetylase inhibitors is due to their targeting cell cycle checkpoint points. European Journal of Cancer, 38, S95-S95. |
