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2023

Conference Publication

MITF-mediated changes of tumour architecture, tensile stress and in extracellular matrix (ECM) control intratumour heterogeneity in melanoma

Spoerri, L., Tonnessen-Murray, C. A., Beaumont, K. A., Hill, D. S., Jurek, R. J., Gunasingh, G., Vanwalleghem, G., Daignault, S., Fane, M. E., Schaider, H., Smith, A., Stehbens, S. J., Weninger, W., Scott, E. E., Gabrielli, B. and Haass, N. (2023). MITF-mediated changes of tumour architecture, tensile stress and in extracellular matrix (ECM) control intratumour heterogeneity in melanoma. Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF), Berlin, Germany, 11-14 March 2020. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

MITF-mediated changes of tumour architecture, tensile stress and in extracellular matrix (ECM) control intratumour heterogeneity in melanoma

2019

Conference Publication

Inhibition of Aurora B kinase activity triggers senescence that can be bypassed by blocking p53 and RB function, promoting replication stress

Andrews, Ariel, Kumar, Ramyashree Prasanna, Nazareth, Deborah, Ehmann, Anna, Hooper, John, McMillan, Nigel and Gabrielli, Brian (2019). Inhibition of Aurora B kinase activity triggers senescence that can be bypassed by blocking p53 and RB function, promoting replication stress. AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, Boston, MA USA, 26-30 October 2019. Philadelphia, PA USA: American Association for Cancer Research. doi: 10.1158/1535-7163.TARG-19-A060

Inhibition of Aurora B kinase activity triggers senescence that can be bypassed by blocking p53 and RB function, promoting replication stress

2019

Conference Publication

Bortezomib-induced immunogenic cell death enhances immune response in melanoma

Daignault, S. M., Ju, R., Spoerri, L., Stehbens, S. J., Hill, D. S., Gabrielli, B., Dolcetti, R. and Haass, N. K. (2019). Bortezomib-induced immunogenic cell death enhances immune response in melanoma. Society for Investigative Dermatology (SID) Meeting, Chicago, IL United States, 8-11 May 2019. London, United Kingdom: Nature Publishing Group. doi: 10.1016/j.jid.2019.03.907

Bortezomib-induced immunogenic cell death enhances immune response in melanoma

2019

Conference Publication

Subclinical doses and choice of replication stress inducer in combination with CHK1 inhibitors for optimal tumor control and immune responses in vitro and in vivo

Oo, Zay Yar, Proctor, Martina, Stevenson, Alex, Nazareth, Deborah, Larsen, Jill, Haass, Nikolas and Gabrielli, Brian G. (2019). Subclinical doses and choice of replication stress inducer in combination with CHK1 inhibitors for optimal tumor control and immune responses in vitro and in vivo. AACR Annual Meeting on Bioinformatics, Convergence Science, and Systems Biology, Atlanta Ga, Mar 29-Apr 03, 2019. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.AM2019-1236

Subclinical doses and choice of replication stress inducer in combination with CHK1 inhibitors for optimal tumor control and immune responses in vitro and in vivo

2018

Conference Publication

Overexpression of the cell cycle regulator Emi1 promotes chromosome instability and tumorigenesis

Duijf, Pascal H. G., Vaidyanathan, Srividya, Cato, Kathleen, Thangavelu, Pulari U., Lin, Cheng-Yu, Tang, Lu, Pavey, Sandra, Haass, Nikolas K. and Gabrielli, Brian G. (2018). Overexpression of the cell cycle regulator Emi1 promotes chromosome instability and tumorigenesis. 76th Annual Meeting of the Japanese Cancer Association, Yokohama, Japan, 28-30 September 2017. Tokyo, Japan: Wiley Japan. doi: 10.1111/cas.13499

Overexpression of the cell cycle regulator Emi1 promotes chromosome instability and tumorigenesis

2018

Conference Publication

Distinct epigenetic remodelling defines early stress-induced drug tolerance in melanoma

Emran, A., Marzese, D. M., Menon, D. R., Stark, M., Torrano, J., Hammerlindl, H., Zhang, G., Brafford, P., Hammerlindl, S., Gupta, D., Mills, G. B., Lu, Y., Flaherty, K., Sturm, R., Hoon, D. S. B., Gabrielli, B., Herlyn, M. and Schaider, H. (2018). Distinct epigenetic remodelling defines early stress-induced drug tolerance in melanoma. Australasian College of Dermatologists, 51st Annual Scientific Meeting, Gold Coast, QLD, Australia , 19–22 May 2018. Richmond, VIC, Australia: Wiley-Blackwell Publishing. doi: 10.1111/ajd.16_12815

Distinct epigenetic remodelling defines early stress-induced drug tolerance in melanoma

2018

Conference Publication

Targeting cell cycle phase-specific drug sensitivity for melanoma therapy

Daignault, S. M., Hill, D. S., Spoerri, L., Stehbens, S., Weninger, W., Gabrielli, B., Dolcetti, R. and Haass, N. K. (2018). Targeting cell cycle phase-specific drug sensitivity for melanoma therapy. 45th Annual Meeting of the Arbeitsgemeinscha-Dermatologische-Forschung (ADF), Zurich, Switzerland, 7-10 March 2018. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.

Targeting cell cycle phase-specific drug sensitivity for melanoma therapy

2017

Conference Publication

Cell cycle-tailored targeting of metastatic melanoma: challenges and opportunities

Haass, N., Spoerri, L., Tonnessen, C. A., Beaumont, K. A., Hill, D. S., Daignault, S. M., Gabrielli, B. and Weninger, W. (2017). Cell cycle-tailored targeting of metastatic melanoma: challenges and opportunities. Australasian College of Dermatologists 50th Annual Scientific Meeting, International Convention Centre, Sydney, NSW Australia, 6-9 May 2017. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.20_12652

Cell cycle-tailored targeting of metastatic melanoma: challenges and opportunities

2016

Conference Publication

Cell cycle phase-specific drug resistance as an escape mechanism of melanoma cells

Beaumont, K., Hill, D., Daignault, S., Sharp, D., Gabrielli, B., Weninger, W. and Haass, N. (2016). Cell cycle phase-specific drug resistance as an escape mechanism of melanoma cells. Annual Meeting of the Society-for-Investigative-Dermatology (SID), Scottsdale, AZ, United States, 11-14 May 2016. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2016.02.695

Cell cycle phase-specific drug resistance as an escape mechanism of melanoma cells

2016

Conference Publication

Global histone modifications define early stress induced drug tolerance in cancer

Al Emran, Abdullah, Menon, Dinoop Ravindran, Soyer, Peter, Gabrielli, Brian, Sturm, Rick, Herlyn, Meenhard and Schaider, Helmut (2016). Global histone modifications define early stress induced drug tolerance in cancer. American-Association-for-Cancer-Research (AACR) Special Conference on Chromatin and Epigenetics in Cancer, Atlanta, GA, United States, 24-27 September 2015. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.CHROMEPI15-B34

Global histone modifications define early stress induced drug tolerance in cancer

2016

Conference Publication

Inhibition of Aurora Kinases is curative for HPV-driven tumours

McMillan, N., Fallaha, S., Martin, D., Leggatt, G. and Gabrielli, B. (2016). Inhibition of Aurora Kinases is curative for HPV-driven tumours. 16th Biennial Meeting of the International Gynecologic Cancer Society, Lisbon, Portugal, 28-31 October 2016. London, United Kingdom: Lippincott Williams & Wilkins. doi: 10.1097/01.IGC.0000503327.50238.5c

Inhibition of Aurora Kinases is curative for HPV-driven tumours

2015

Conference Publication

Abstract 945: synthetic lethal screen identifies Aurora A as a selective target in HPV driven cervical cancer

Gabrielli, Brian G., Bokhari, Fawzi, Ranall, Max, Oo, Zay Yar, Stevenson, Alex, Wang, Weili, McKee, Sara, Leggatt, Graham, Leo, Paul, Gonda, Thomas J. and McMillan, Nigel A. J. (2015). Abstract 945: synthetic lethal screen identifies Aurora A as a selective target in HPV driven cervical cancer. 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Philadelphia, PA United States, 18-22 April 2015. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2015-945

Abstract 945: synthetic lethal screen identifies Aurora A as a selective target in HPV driven cervical cancer

2015

Conference Publication

Melanoma cells in G1 phase escape proteasome inhibitor cytotoxicity

Hill, D. S., Beaumont, K. A., Daignault, S. M., Anfosso, A., Sharp, D. M., Gabrielli, B., Lovat, P. E., Weninger, W. and Haass, N. K. (2015). Melanoma cells in G1 phase escape proteasome inhibitor cytotoxicity. 42nd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Ulm, Germany, Mar 05-07, 2015. Chichester, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/exd.12623

Melanoma cells in G1 phase escape proteasome inhibitor cytotoxicity

2014

Conference Publication

Synthetic lethal screen identifies Aurora A as a selective target in HPV driven cervical cancer

Gabrielli, B., Bokhari, F., Ranall, M., Stevenson, A., Murell, M., Kelly, M., McKee, S., Leggatt, G., Gonda, T. and McMillan, N. (2014). Synthetic lethal screen identifies Aurora A as a selective target in HPV driven cervical cancer. 26th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Barcelona Spain, 18-21 November 2014. Abingdon, Oxford, United Kingdom: Elsevier. doi: 10.1016/S0959-8049(14)70420-4

Synthetic lethal screen identifies Aurora A as a selective target in HPV driven cervical cancer

2013

Conference Publication

Chk1 inhibitor targets replicative stress in melanomas

Gabrielli, Brian G., Brooks, Kelly, Edwards, Brooke, Chen, James and Pavey, Sandra (2013). Chk1 inhibitor targets replicative stress in melanomas. 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington Dc, Apr 06-10, 2013. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.AM2013-3425

Chk1 inhibitor targets replicative stress in melanomas

2012

Conference Publication

Chk1 inhibitor targets replicative stress in melanomas

Gabrielli, B., Brooks, K., Oakes, V., Edwards, B., Chen, J. and Mukhopadhyay, P. (2012). Chk1 inhibitor targets replicative stress in melanomas. 24th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Dublin Ireland, 6-9 November 2012. Oxford, United Kingdom: Pergamon. doi: 10.1158/1538-7445.AM2013-3425

Chk1 inhibitor targets replicative stress in melanomas

2012

Conference Publication

A Genome-wide Human ORF Gain-of-function Screen to Identify Genes that can Bypass p16INK4a-mediated Cellular Senescence

Lee, W. J., Skalamera, D., Dahmer, M., Shakhbazov, K., Purdon, A., Wilson, B., Ranall, M, Pinder, A., Pavey, S., Gonda, T. and Gabrielli, B. (2012). A Genome-wide Human ORF Gain-of-function Screen to Identify Genes that can Bypass p16INK4a-mediated Cellular Senescence. 6th Australian High Content Screening Group Meeting, Melbourne, Australia, 13th July 2012.

A Genome-wide Human ORF Gain-of-function Screen to Identify Genes that can Bypass p16INK4a-mediated Cellular Senescence

2011

Conference Publication

Abstract 4197: A DNA damage checkpoint response to unrepaired ultraviolet radiation-induced lesions which is defective in melanoma

Wigan, Matthew, Pavey, Sandra, Brooks, Kelly, Giles, Nichole, Burgess, Andrew, Sturm, Rick and Gabrielli, Brian (2011). Abstract 4197: A DNA damage checkpoint response to unrepaired ultraviolet radiation-induced lesions which is defective in melanoma. AACR 102nd Annual Meeting 2011, Orlando, FL United States, 2‐6 April 2011. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2011-4197

Abstract 4197: A DNA damage checkpoint response to unrepaired ultraviolet radiation-induced lesions which is defective in melanoma

2011

Conference Publication

A high-coverage and high-content human ORF overexpression screen to identify pathways that can bypass p16INK4a-mediated cellular senescence

Lee, W. J., Skalamera, D. and Gabrielli, B. (2011). A high-coverage and high-content human ORF overexpression screen to identify pathways that can bypass p16INK4a-mediated cellular senescence. 5th Australian High Content Screening Group Meeting, Melbourme, Australia, 15 July 2011.

A high-coverage and high-content human ORF overexpression screen to identify pathways that can bypass p16INK4a-mediated cellular senescence

2011

Conference Publication

A functional genomics approach to identify genes and pathways that can bypass p16INK4a-mediated cellular senescence

Lee, W. J., Skalamera, D., Dahmer, M., Shakhbazov, K., Ranall, M., Purdon, A., Wilson, B., Pinder, A., Pavey, S., Gonda, T. and Gabrielli, B. (2011). A functional genomics approach to identify genes and pathways that can bypass p16INK4a-mediated cellular senescence. 14th Annual Australian Cell Cycle Workshop, Noosa, Australia, 24 October 2011.

A functional genomics approach to identify genes and pathways that can bypass p16INK4a-mediated cellular senescence