2012 Conference Publication Chk1 inhibitor targets replicative stress in melanomasGabrielli, B., Brooks, K., Oakes, V., Edwards, B., Chen, J. and Mukhopadhyay, P. (2012). Chk1 inhibitor targets replicative stress in melanomas. 24th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Dublin Ireland, 6-9 November 2012. Oxford, United Kingdom: Pergamon. doi: 10.1158/1538-7445.AM2013-3425 |
2012 Journal Article Histone deacetylase inhibitors disrupt the mitotic spindle assembly checkpoint by targeting histone and nonhistone proteinsGabrielli, Brian and Brown, Melissa (2012). Histone deacetylase inhibitors disrupt the mitotic spindle assembly checkpoint by targeting histone and nonhistone proteins. Advances in Cancer Research, 116, 1-37. doi: 10.1016/B978-0-12-394387-3.00001-X |
2011 Journal Article Abstract A65: Targeting the defective decatenation checkpoint in melanoma.Brooks, Kelly M., Ranall, Max, Pavey, Sandra, Mukhopadhyay, Pamela, Wigan, Matthew, Giles, Nicole and Gabrielli, Brian (2011). Abstract A65: Targeting the defective decatenation checkpoint in melanoma.. Molecular Cancer Therapeutics, 10 (11_Supplement). doi: 10.1158/1535-7163.targ-11-a65 |
2011 Journal Article Finally, how histone deacetylase inhibitors disrupt mitosis!Gabrielli, Brian, Chia, KeeMing and Warrener, Robyn (2011). Finally, how histone deacetylase inhibitors disrupt mitosis!. Cell Cycle, 10 (16), 2658-2661. doi: 10.4161/cc.10.16.16953 |
2011 Journal Article High-content imaging of neutral lipid droplets with 1,6-diphenylhexatrieneRanall, Max V., Gabrielli, Brian g. and Gonda, Thomas J. (2011). High-content imaging of neutral lipid droplets with 1,6-diphenylhexatriene. Biotechniques, 51 (1), 35-42. doi: 10.2144/000113702 |
2011 Journal Article Phosphorylation of Cdc25B3 Ser169 regulates 14-3-3 binding to Ser151 and Cdc25B activityAstuti, Puji and Gabrielli, Brian (2011). Phosphorylation of Cdc25B3 Ser169 regulates 14-3-3 binding to Ser151 and Cdc25B activity. Cell Cycle, 10 (12), 1960-1967. doi: 10.4161/cc.10.12.15819 |
2011 Journal Article A high-throughput platform for lentiviral overexpression screening of the human ORFeomeŠkalamera, Dubravka, Ranall, Max V., Wilson, Benjamin M., Leo, Paul, Purdon, Amy S., Hyde, Carolyn, Nourbakhsh, Ehsan, Grimmond, Sean M., Barry, Simon C., Gabrielli, Brian and Gonda, Thomas J. (2011). A high-throughput platform for lentiviral overexpression screening of the human ORFeome. PLoS One, 6 (5) e20057, e20057.1-e20057.14. doi: 10.1371/journal.pone.0020057 |
2011 Journal Article Evidence for label-retaining tumour-initiating cells in human glioblastomaDeleyrolle, Loic P., Harding, Angus, Cato, Kathleen, Siebzehnrubl, Florian A., Rahman, Maryam, Azari, Hassan, Olson, Sarah, Gabrielli, Brian, Osborne, Geoffrey, Vescovi, Angelo and Reynolds, Brent A. (2011). Evidence for label-retaining tumour-initiating cells in human glioblastoma. Brain, 134 (5), 1331-1343. doi: 10.1093/brain/awr081 |
2011 Conference Publication Abstract 4197: A DNA damage checkpoint response to unrepaired ultraviolet radiation-induced lesions which is defective in melanomaWigan, Matthew, Pavey, Sandra, Brooks, Kelly, Giles, Nichole, Burgess, Andrew, Sturm, Rick and Gabrielli, Brian (2011). Abstract 4197: A DNA damage checkpoint response to unrepaired ultraviolet radiation-induced lesions which is defective in melanoma. AACR 102nd Annual Meeting 2011, Orlando, FL United States, 2‐6 April 2011. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2011-4197 |
2011 Journal Article CDC25B associates with a centrin 2-containing complex and is involved in maintaining centrosome integrityBoutros, Rose, Lorenzo, Corinne, Mondesert, Odile, Jauneau, Alain, Oakes,Vanessa, Dozier, Christine, Gabrielli, Brian and Ducommun, Bernard (2011). CDC25B associates with a centrin 2-containing complex and is involved in maintaining centrosome integrity. Biology of the Cell, 103 (2), 55-68. doi: 10.1042/BC20100111 |
2011 Conference Publication A high-coverage and high-content human ORF overexpression screen to identify pathways that can bypass p16INK4a-mediated cellular senescenceLee, W. J., Skalamera, D. and Gabrielli, B. (2011). A high-coverage and high-content human ORF overexpression screen to identify pathways that can bypass p16INK4a-mediated cellular senescence. 5th Australian High Content Screening Group Meeting, Melbourme, Australia, 15 July 2011. |
2011 Conference Publication A functional genomics approach to identify genes and pathways that can bypass p16INK4a-mediated cellular senescenceLee, W. J., Skalamera, D., Dahmer, M., Shakhbazov, K., Ranall, M., Purdon, A., Wilson, B., Pinder, A., Pavey, S., Gonda, T. and Gabrielli, B. (2011). A functional genomics approach to identify genes and pathways that can bypass p16INK4a-mediated cellular senescence. 14th Annual Australian Cell Cycle Workshop, Noosa, Australia, 24 October 2011. |
2010 Journal Article Mitotic phosphorylation of Cdc25B Ser(321) disrupts 14-3-3 binding to the high affinity Ser(323) siteAstuti, P, Boutros, R, Ducommun, B and Gabrielli, B (2010). Mitotic phosphorylation of Cdc25B Ser(321) disrupts 14-3-3 binding to the high affinity Ser(323) site. Journal of Biological Chemistry, 285 (45), 34364-34370. doi: 10.1074/jbc.M110.138412 |
2010 Journal Article Inhibition of histone deacetylase 3 produces mitotic defects independent of alterations in histone H3 lysine 9 acetylation and methylationWarrener, Robyn, Chia, KeeMing, Warren, William D., Brooks, Kelly and Gabrielli, Brian (2010). Inhibition of histone deacetylase 3 produces mitotic defects independent of alterations in histone H3 lysine 9 acetylation and methylation. Molecular Pharmacology, 78 (3), 384-393. doi: 10.1124/mol.109.062976 |
2010 Journal Article The histone deacetylase inhibitor MGCD0103 has both deacetylase and microtubule inhibitory activityChia, K, Beamish, H, Jafferi, K and Gabrielli, B (2010). The histone deacetylase inhibitor MGCD0103 has both deacetylase and microtubule inhibitory activity. Molecular Pharmacology, 78 (3), 436-443. doi: 10.1124/mol.110.065169 |
2010 Journal Article Adaptation and validation of DNA synthesis detection by fluorescent dye derivatization for high throughput screeningRanall, Max V., Gabrielli, Brian G. and Gonda, Thomas J. (2010). Adaptation and validation of DNA synthesis detection by fluorescent dye derivatization for high throughput screening. BioTechniques, 48 (5), 379-386. doi: 10.2144/000113410 |
2010 Conference Publication Fatty acids induce hepatocyte senescence in vitro: implications for pathogenesis in non-alcoholic steatohepatitisSkoien, R., Powell, E. E., Melino, M., Clouston, A. D., Gabrielli, B. G. and Jonsson, J. R. (2010). Fatty acids induce hepatocyte senescence in vitro: implications for pathogenesis in non-alcoholic steatohepatitis. Australian Gastroenterology Week 2010, Gold Coast, QLD, Australia, 20-23 October 2010. Richmond, VIC, Australia: Wiley-Blackwell Publishing. doi: 10.1111/j.1440-1746.2010.06450.x |
2009 Journal Article MAPK pathway activation delays G(2)/M progression by destabilizing Cdc25BAstuti, P, Pike, T, Widberg, C, Payne, E, Harding, A, Hancock, J and Gabrielli, B (2009). MAPK pathway activation delays G(2)/M progression by destabilizing Cdc25B. Journal of Biological Chemistry, 284 (49), 33781-33788. doi: 10.1074/jbc.M109.027516 |
2009 Journal Article Cyclin A/cdk2 regulates adenomatous polyposis coli-dependent mitotic spindle anchoringBeamish, Heather, De Boer, Leonore, Giles, Nichole, Stevens, Frankie, Oakes, Vanessa and Gabrielli, Brian (2009). Cyclin A/cdk2 regulates adenomatous polyposis coli-dependent mitotic spindle anchoring. Journal of Biological Chemistry, 284 (42), 29015-29023. doi: 10.1074/jbc.M109.042820 |
2009 Journal Article CtBPs promote cell survival through the maintenance of mitotic fidelityBergman, Lee M., Birts, Charles N., Darley, Matthew, Gabrielli, Brian and Blaydes, Jeremy P. (2009). CtBPs promote cell survival through the maintenance of mitotic fidelity. Molecular and Cellular Biology, 29 (16), 4539-4551. doi: 10.1128/MCB.00439-09 |