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2012

Conference Publication

Chk1 inhibitor targets replicative stress in melanomas

Gabrielli, B., Brooks, K., Oakes, V., Edwards, B., Chen, J. and Mukhopadhyay, P. (2012). Chk1 inhibitor targets replicative stress in melanomas. 24th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Dublin Ireland, 6-9 November 2012. Oxford, United Kingdom: Pergamon. doi: 10.1158/1538-7445.AM2013-3425

Chk1 inhibitor targets replicative stress in melanomas

2012

Journal Article

Histone deacetylase inhibitors disrupt the mitotic spindle assembly checkpoint by targeting histone and nonhistone proteins

Gabrielli, Brian and Brown, Melissa (2012). Histone deacetylase inhibitors disrupt the mitotic spindle assembly checkpoint by targeting histone and nonhistone proteins. Advances in Cancer Research, 116, 1-37. doi: 10.1016/B978-0-12-394387-3.00001-X

Histone deacetylase inhibitors disrupt the mitotic spindle assembly checkpoint by targeting histone and nonhistone proteins

2011

Journal Article

Abstract A65: Targeting the defective decatenation checkpoint in melanoma.

Brooks, Kelly M., Ranall, Max, Pavey, Sandra, Mukhopadhyay, Pamela, Wigan, Matthew, Giles, Nicole and Gabrielli, Brian (2011). Abstract A65: Targeting the defective decatenation checkpoint in melanoma.. Molecular Cancer Therapeutics, 10 (11_Supplement). doi: 10.1158/1535-7163.targ-11-a65

Abstract A65: Targeting the defective decatenation checkpoint in melanoma.

2011

Journal Article

Finally, how histone deacetylase inhibitors disrupt mitosis!

Gabrielli, Brian, Chia, KeeMing and Warrener, Robyn (2011). Finally, how histone deacetylase inhibitors disrupt mitosis!. Cell Cycle, 10 (16), 2658-2661. doi: 10.4161/cc.10.16.16953

Finally, how histone deacetylase inhibitors disrupt mitosis!

2011

Journal Article

High-content imaging of neutral lipid droplets with 1,6-diphenylhexatriene

Ranall, Max V., Gabrielli, Brian g. and Gonda, Thomas J. (2011). High-content imaging of neutral lipid droplets with 1,6-diphenylhexatriene. Biotechniques, 51 (1), 35-42. doi: 10.2144/000113702

High-content imaging of neutral lipid droplets with 1,6-diphenylhexatriene

2011

Journal Article

Phosphorylation of Cdc25B3 Ser169 regulates 14-3-3 binding to Ser151 and Cdc25B activity

Astuti, Puji and Gabrielli, Brian (2011). Phosphorylation of Cdc25B3 Ser169 regulates 14-3-3 binding to Ser151 and Cdc25B activity. Cell Cycle, 10 (12), 1960-1967. doi: 10.4161/cc.10.12.15819

Phosphorylation of Cdc25B3 Ser169 regulates 14-3-3 binding to Ser151 and Cdc25B activity

2011

Journal Article

A high-throughput platform for lentiviral overexpression screening of the human ORFeome

Škalamera, Dubravka, Ranall, Max V., Wilson, Benjamin M., Leo, Paul, Purdon, Amy S., Hyde, Carolyn, Nourbakhsh, Ehsan, Grimmond, Sean M., Barry, Simon C., Gabrielli, Brian and Gonda, Thomas J. (2011). A high-throughput platform for lentiviral overexpression screening of the human ORFeome. PLoS One, 6 (5) e20057, e20057.1-e20057.14. doi: 10.1371/journal.pone.0020057

A high-throughput platform for lentiviral overexpression screening of the human ORFeome

2011

Journal Article

Evidence for label-retaining tumour-initiating cells in human glioblastoma

Deleyrolle, Loic P., Harding, Angus, Cato, Kathleen, Siebzehnrubl, Florian A., Rahman, Maryam, Azari, Hassan, Olson, Sarah, Gabrielli, Brian, Osborne, Geoffrey, Vescovi, Angelo and Reynolds, Brent A. (2011). Evidence for label-retaining tumour-initiating cells in human glioblastoma. Brain, 134 (5), 1331-1343. doi: 10.1093/brain/awr081

Evidence for label-retaining tumour-initiating cells in human glioblastoma

2011

Conference Publication

Abstract 4197: A DNA damage checkpoint response to unrepaired ultraviolet radiation-induced lesions which is defective in melanoma

Wigan, Matthew, Pavey, Sandra, Brooks, Kelly, Giles, Nichole, Burgess, Andrew, Sturm, Rick and Gabrielli, Brian (2011). Abstract 4197: A DNA damage checkpoint response to unrepaired ultraviolet radiation-induced lesions which is defective in melanoma. AACR 102nd Annual Meeting 2011, Orlando, FL United States, 2‐6 April 2011. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2011-4197

Abstract 4197: A DNA damage checkpoint response to unrepaired ultraviolet radiation-induced lesions which is defective in melanoma

2011

Journal Article

CDC25B associates with a centrin 2-containing complex and is involved in maintaining centrosome integrity

Boutros, Rose, Lorenzo, Corinne, Mondesert, Odile, Jauneau, Alain, Oakes,Vanessa, Dozier, Christine, Gabrielli, Brian and Ducommun, Bernard (2011). CDC25B associates with a centrin 2-containing complex and is involved in maintaining centrosome integrity. Biology of the Cell, 103 (2), 55-68. doi: 10.1042/BC20100111

CDC25B associates with a centrin 2-containing complex and is involved in maintaining centrosome integrity

2011

Conference Publication

A high-coverage and high-content human ORF overexpression screen to identify pathways that can bypass p16INK4a-mediated cellular senescence

Lee, W. J., Skalamera, D. and Gabrielli, B. (2011). A high-coverage and high-content human ORF overexpression screen to identify pathways that can bypass p16INK4a-mediated cellular senescence. 5th Australian High Content Screening Group Meeting, Melbourme, Australia, 15 July 2011.

A high-coverage and high-content human ORF overexpression screen to identify pathways that can bypass p16INK4a-mediated cellular senescence

2011

Conference Publication

A functional genomics approach to identify genes and pathways that can bypass p16INK4a-mediated cellular senescence

Lee, W. J., Skalamera, D., Dahmer, M., Shakhbazov, K., Ranall, M., Purdon, A., Wilson, B., Pinder, A., Pavey, S., Gonda, T. and Gabrielli, B. (2011). A functional genomics approach to identify genes and pathways that can bypass p16INK4a-mediated cellular senescence. 14th Annual Australian Cell Cycle Workshop, Noosa, Australia, 24 October 2011.

A functional genomics approach to identify genes and pathways that can bypass p16INK4a-mediated cellular senescence

2010

Journal Article

Mitotic phosphorylation of Cdc25B Ser(321) disrupts 14-3-3 binding to the high affinity Ser(323) site

Astuti, P, Boutros, R, Ducommun, B and Gabrielli, B (2010). Mitotic phosphorylation of Cdc25B Ser(321) disrupts 14-3-3 binding to the high affinity Ser(323) site. Journal of Biological Chemistry, 285 (45), 34364-34370. doi: 10.1074/jbc.M110.138412

Mitotic phosphorylation of Cdc25B Ser(321) disrupts 14-3-3 binding to the high affinity Ser(323) site

2010

Journal Article

Inhibition of histone deacetylase 3 produces mitotic defects independent of alterations in histone H3 lysine 9 acetylation and methylation

Warrener, Robyn, Chia, KeeMing, Warren, William D., Brooks, Kelly and Gabrielli, Brian (2010). Inhibition of histone deacetylase 3 produces mitotic defects independent of alterations in histone H3 lysine 9 acetylation and methylation. Molecular Pharmacology, 78 (3), 384-393. doi: 10.1124/mol.109.062976

Inhibition of histone deacetylase 3 produces mitotic defects independent of alterations in histone H3 lysine 9 acetylation and methylation

2010

Journal Article

The histone deacetylase inhibitor MGCD0103 has both deacetylase and microtubule inhibitory activity

Chia, K, Beamish, H, Jafferi, K and Gabrielli, B (2010). The histone deacetylase inhibitor MGCD0103 has both deacetylase and microtubule inhibitory activity. Molecular Pharmacology, 78 (3), 436-443. doi: 10.1124/mol.110.065169

The histone deacetylase inhibitor MGCD0103 has both deacetylase and microtubule inhibitory activity

2010

Journal Article

Adaptation and validation of DNA synthesis detection by fluorescent dye derivatization for high throughput screening

Ranall, Max V., Gabrielli, Brian G. and Gonda, Thomas J. (2010). Adaptation and validation of DNA synthesis detection by fluorescent dye derivatization for high throughput screening. BioTechniques, 48 (5), 379-386. doi: 10.2144/000113410

Adaptation and validation of DNA synthesis detection by fluorescent dye derivatization for high throughput screening

2010

Conference Publication

Fatty acids induce hepatocyte senescence in vitro: implications for pathogenesis in non-alcoholic steatohepatitis

Skoien, R., Powell, E. E., Melino, M., Clouston, A. D., Gabrielli, B. G. and Jonsson, J. R. (2010). Fatty acids induce hepatocyte senescence in vitro: implications for pathogenesis in non-alcoholic steatohepatitis. Australian Gastroenterology Week 2010, Gold Coast, QLD, Australia, 20-23 October 2010. Richmond, VIC, Australia: Wiley-Blackwell Publishing. doi: 10.1111/j.1440-1746.2010.06450.x

Fatty acids induce hepatocyte senescence in vitro: implications for pathogenesis in non-alcoholic steatohepatitis

2009

Journal Article

MAPK pathway activation delays G(2)/M progression by destabilizing Cdc25B

Astuti, P, Pike, T, Widberg, C, Payne, E, Harding, A, Hancock, J and Gabrielli, B (2009). MAPK pathway activation delays G(2)/M progression by destabilizing Cdc25B. Journal of Biological Chemistry, 284 (49), 33781-33788. doi: 10.1074/jbc.M109.027516

MAPK pathway activation delays G(2)/M progression by destabilizing Cdc25B

2009

Journal Article

Cyclin A/cdk2 regulates adenomatous polyposis coli-dependent mitotic spindle anchoring

Beamish, Heather, De Boer, Leonore, Giles, Nichole, Stevens, Frankie, Oakes, Vanessa and Gabrielli, Brian (2009). Cyclin A/cdk2 regulates adenomatous polyposis coli-dependent mitotic spindle anchoring. Journal of Biological Chemistry, 284 (42), 29015-29023. doi: 10.1074/jbc.M109.042820

Cyclin A/cdk2 regulates adenomatous polyposis coli-dependent mitotic spindle anchoring

2009

Journal Article

CtBPs promote cell survival through the maintenance of mitotic fidelity

Bergman, Lee M., Birts, Charles N., Darley, Matthew, Gabrielli, Brian and Blaydes, Jeremy P. (2009). CtBPs promote cell survival through the maintenance of mitotic fidelity. Molecular and Cellular Biology, 29 (16), 4539-4551. doi: 10.1128/MCB.00439-09

CtBPs promote cell survival through the maintenance of mitotic fidelity