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2024 Journal Article A glucocorticoid spike derails muscle repair to heterotopic ossification after spinal cord injuryAlexander, Kylie A., Tseng, Hsu-Wen, Lao, Hong Wa, Girard, Dorothée, Barbier, Valérie, Ungerer, Jacobus P. J., McWhinney, Brett C., Samuel, Selwin G., Fleming, Whitney, Winkler, Ingrid G., Salga, Marjorie, Genêt, François, Banzet, Sébastien, Ruitenberg, Marc J. and Lévesque, Jean-Pierre (2024). A glucocorticoid spike derails muscle repair to heterotopic ossification after spinal cord injury. Cell Reports Medicine, 5 (12) 101849, 101849. doi: 10.1016/j.xcrm.2024.101849 |
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2024 Journal Article Interleukin-6 does not contribute to neurogenic heterotopic ossification pathogenesisGirard, Dorothee, Tseng, Hsu-Wen, Rival, Bastien, Barbier, Valerie, Shatunova, Svetlana, Goriot, Marie-Emmanuelle, Samuel, Selwin Gabriel, Genet, Francois, Salga, Marjorie, Banzet, Sebastien, Alexander, Kylie A. and Levesque, Jean-Pierre (2024). Interleukin-6 does not contribute to neurogenic heterotopic ossification pathogenesis. Neurotrauma Reports, 5 (1), 1101-1112. doi: 10.1089/neur.2024.0106 |
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2024 Journal Article Autophagy prevents graft failure during murine Graft versus Host DiseaseLineburg, Katie E., Leveque-El Mouttie, Lucie, Hunter, Christopher R., Le Texier, Laeitia, McGirr, Crystal, Teal, Bianca, Blazar, Bruce R., Lane, Steven W., Hill, Geoffrey R., Levesque, Jean-Pierre and MacDonald, Kelli P.A. (2024). Autophagy prevents graft failure during murine Graft versus Host Disease. Blood Advances, 8 (8), 2032-2043. doi: 10.1182/bloodadvances.2023010972 |
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2024 Journal Article Oncostatin M: dual regulator of the skeletal and hematopoietic systemsSims, Natalie A. and Lévesque, Jean-Pierre (2024). Oncostatin M: dual regulator of the skeletal and hematopoietic systems. Current Osteoporosis Reports, 22 (1), 80-95. doi: 10.1007/s11914-023-00837-z |
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2023 Journal Article Bacterial Lipopolysaccharides Exacerbate Neurogenic Heterotopic Ossification DevelopmentSalga, Marjorie, Samuel, Selwin G., Tseng, Hsu‐Wen, Gatin, Laure, Girard, Dorothée, Rival, Bastien, Barbier, Valerie, Bisht, Kavita, Shatunova, Svetlana, Debaud, Charlotte, Winkler, Ingrid G., Paquereau, Julie, Dinh, Aurélien, Genêt, Guillaume, Kerever, Sébastien, Abback, Paer‐Sélim, Banzet, Sébastien, Genêt, François, Lévesque, Jean‐Pierre and Alexander, Kylie A. (2023). Bacterial Lipopolysaccharides Exacerbate Neurogenic Heterotopic Ossification Development. Journal of Bone and Mineral Research, 38 (11), 1-18. doi: 10.1002/jbmr.4905 |
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2023 Journal Article GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infectionFoo, Cheng Xiang, Bartlett, Stacey, Chew, Keng Yih, Ngo, Minh Dao, Bielefeldt-Ohmann, Helle, Jayakody Arachchige, Buddhika, Matthews, Benjamin, Reed, Sarah, Wang, Ran, Smith, Christian, Sweet, Matthew J., Burr, Lucy, Bisht, Kavita, Shatunova, Svetlana, Sinclair, Jane E., Parry, Rhys, Yang, Yuanhao, Lévesque, Jean-Pierre, Khromykh, Alexander, Rosenkilde, Mette Marie, Short, Kirsty R. and Ronacher, Katharina (2023). GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infection. European Respiratory Journal, 61 (3) 2201306, 1-15. doi: 10.1183/13993003.01306-2022 |
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2022 Journal Article Inflammasomes and the IL-1 family in bone homeostasis and diseaseTseng, Hsu-Wen, Samuel, Selwin Gabriel, Schroder, Kate, Lévesque, Jean-Pierre and Alexander, Kylie A (2022). Inflammasomes and the IL-1 family in bone homeostasis and disease. Current Osteoporosis Reports, 20 (3), 170-185. doi: 10.1007/s11914-022-00729-8 |
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2022 Journal Article Interleukin‐1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossificationTseng, Hsu‐Wen, Kulina, Irina, Girard, Dorothée, Gueguen, Jules, Vaquette, Cedryck, Salga, Marjorie, Fleming, Whitney, Jose, Beulah, Millard, Susan M., Pettit, Allison R., Schroder, Kate, Thomas, Gethin, Wheeler, Lawrie, Genêt, François, Banzet, Sébastien, Alexander, Kylie A. and Levesque, Jean‐Pierre (2022). Interleukin‐1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification. Journal of Bone and Mineral Research, 37 (3), 531-546. doi: 10.1002/jbmr.4482 |
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2022 Journal Article Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within musclesTseng, Hsu-Wen, Girard, Dorothée, Alexander, Kylie A., Millard, Susan M., Torossian, Frédéric, Anginot, Adrienne, Fleming, Whitney, Gueguen, Jules, Goriot, Marie-Emmanuelle, Clay, Denis, Jose, Beulah, Nowlan, Bianca, Pettit, Allison R., Salga, Marjorie, Genêt, François, Bousse-Kerdilès, Marie-Caroline Le, Banzet, Sébastien and Lévesque, Jean-Pierre (2022). Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles. Bone Research, 10 (1) 22, 22. doi: 10.1038/s41413-022-00188-y |
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2022 Journal Article Lymphocytes are not required for neurogenic heterotopic ossification development after spinal cord injuryAlexander, Kylie A., Tseng, Hsu-Wen, Kulina, Irina, Fleming, Whitney, Vaquette, Cedryck, Genêt, François, Ruitenberg, Marc J. and Lévesque, Jean-Pierre (2022). Lymphocytes are not required for neurogenic heterotopic ossification development after spinal cord injury. Neurotrauma Reports, 3 (1), 87-96. doi: 10.1089/neur.2021.0072 |
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2021 Journal Article Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissuesMillard, Susan M., Heng, Ostyn, Opperman, Khatora S., Sehgal, Anuj, Irvine, Katharine M., Kaur, Simranpreet, Sandrock, Cheyenne J., Wu, Andy C., Magor, Graham W., Batoon, Lena, Perkins, Andrew C., Noll, Jacqueline E., Zannettino, Andrew C.W., Sester, David P., Levesque, Jean-Pierre, Hume, David A., Raggatt, Liza J., Summers, Kim M. and Pettit, Allison R. (2021). Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues. Cell Reports, 37 (8) 110058, 110058. doi: 10.1016/j.celrep.2021.110058 |
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2021 Journal Article Macrophages form erythropoietic niches and regulate iron homeostasis to adapt erythropoiesis in response to infections and inflammationLévesque, Jean-Pierre, Summers, Kim M., Bisht, Kavita, Millard, Susan M., Winkler, Ingrid G. and Pettit, Allison R. (2021). Macrophages form erythropoietic niches and regulate iron homeostasis to adapt erythropoiesis in response to infections and inflammation. Experimental Hematology, 103, 1-14. doi: 10.1016/j.exphem.2021.08.011 |
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2021 Journal Article Oncostatin M regulates hematopoietic stem cell (HSC) niches in the bone marrow to restrict HSC mobilizationBisht, Kavita, McGirr, Crystal, Lee, Seo-Youn, Tseng, Hsu-Wen, Fleming, Whitney, Alexander, Kylie A., Matsumoto, Taichi, Barbier, Valérie, Sims, Natalie A., Müller-Newen, Gerhard, Winkler, Ingrid G., Bonig, Halvard and Lévesque, Jean-Pierre (2021). Oncostatin M regulates hematopoietic stem cell (HSC) niches in the bone marrow to restrict HSC mobilization. Leukemia, 36 (2), 333-347. doi: 10.1038/s41375-021-01413-z |
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2021 Journal Article In memory of Paul Sylvain Frenette, a pioneering explorer of the hematopoietic stem cell niche who left far too earlyLévesque, Jean-Pierre, Purton, Louise E., Hidalgo, Andrés, Zon, Leonard, Katayama, Yoshio, Scadden, David, Bowman, Teresa V., Stanley, E. Richard, Lucas, Daniel and Pinho, Sandra (2021). In memory of Paul Sylvain Frenette, a pioneering explorer of the hematopoietic stem cell niche who left far too early. Experimental Hematology, 101-102, 1-6. doi: 10.1016/j.exphem.2021.08.002 |
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2021 Journal Article Role of macrophages and phagocytes in orchestrating normal and pathologic hematopoietic nichesLévesque, Jean-Pierre, Summers, Kim M., Millard, Susan, Bisht, Kavita, Winkler, Ingrid G. and Pettit, Allison R. (2021). Role of macrophages and phagocytes in orchestrating normal and pathologic hematopoietic niches. Experimental Hematology, 100, 12-31. doi: 10.1016/j.exphem.2021.07.001 |
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2021 Journal Article Prostacyclin is an endosteal bone marrow niche component and its clinical analog iloprost protects hematopoietic stem cell potential during stressTay, Joshua, Barbier, Valerie, Helwani, Falak M, Price, Gareth R, Levesque, Jean-Pierre and Winkler, Ingrid G (2021). Prostacyclin is an endosteal bone marrow niche component and its clinical analog iloprost protects hematopoietic stem cell potential during stress. Stem Cells, 39 (11), 1532-1545. doi: 10.1002/stem.3438 |
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2021 Journal Article Local and systemic factors drive ectopic osteogenesis in regenerating muscles of spinal cord-injured mice in a lesion level-dependent mannerDebaud, Charlotte, Tseng, Hsu-Wen, Chedik, Malha, Kulina, Irina, Genêt, François, Ruitenberg, Marc J. and Levesque, Jean-Pierre (2021). Local and systemic factors drive ectopic osteogenesis in regenerating muscles of spinal cord-injured mice in a lesion level-dependent manner. Journal of Neurotrauma, 38 (15) neu.2021.0058, 2162-2175. doi: 10.1089/neu.2021.0058 |
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2021 Journal Article Adhesion to E-selectin primes macrophages for activation through AKT and mTORDavies, Julie M., Radford, Kristen J., Begun, Jakob, Levesque, Jean-Pierre and Winkler, Ingrid G. (2021). Adhesion to E-selectin primes macrophages for activation through AKT and mTOR. Immunology and Cell Biology, 99 (6) imcb.12447, 622-639. doi: 10.1111/imcb.12447 |
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2021 Journal Article Neurogenic heterotopic ossifications recapitulate hematopoietic stem cell niche development within an adult osteogenic muscle environmentGirard, Dorothée, Torossian, Frédéric, Oberlin, Estelle, Alexander, Kylie A., Gueguen, Jules, Tseng, Hsu-Wen, Genêt, François, Lataillade, Jean-Jacques, Salga, Marjorie, Levesque, Jean-Pierre, Le Bousse-Kerdilès, Marie-Caroline and Banzet, Sébastien (2021). Neurogenic heterotopic ossifications recapitulate hematopoietic stem cell niche development within an adult osteogenic muscle environment. Frontiers in Cell and Developmental Biology, 9 611842, 611842. doi: 10.3389/fcell.2021.611842 |
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2021 Journal Article Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β releaseStarobova, Hana, Monteleone, Mercedes, Adolphe, Christelle, Batoon, Lena, Sandrock, Cheyenne J., Tay, Bryan, Deuis, Jennifer R., Smith, Alexandra V., Mueller, Alexander, Nadar, Evelyn Israel, Lawrence, Grace Pamo, Mayor, Amanda, Tolson, Elissa, Levesque, Jean-Pierre, Pettit, Allison R., Wainwright, Brandon J., Schroder, Kate and Vetter, Irina (2021). Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β release. Journal of Experimental Medicine, 218 (5) e20201452. doi: 10.1084/jem.20201452 |
