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2012

Journal Article

Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction

Schroder, Kate, Sagulenko, Vitaliya, Zamoshnikova, Alina, Richards, Ayanthi A., Cridland, Jasmyn A., Irvine, Katharine M., Stacey, Katryn J. and Sweet, Matthew J. (2012). Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction. Immunobiology, 217 (12), 1325-1329. doi: 10.1016/j.imbio.2012.07.020

Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction

2012

Journal Article

The mammalian PYHIN gene family: Phylogeny, evolution and expression

Cridland, Jasmyn A., Curley, Eva Z., Wykes, Michelle N ., Schroder, Kate, Sweet, Matthew J., Roberts, Tara L., Ragan, Mark A., Kassahn, Karin S. and Stacey, Katryn J. (2012). The mammalian PYHIN gene family: Phylogeny, evolution and expression. BMC Evolutionary Biology, 12 (1) 140, 140.1-140.33. doi: 10.1186/1471-2148-12-140

The mammalian PYHIN gene family: Phylogeny, evolution and expression

2012

Journal Article

Towards isozyme-selective HDA inhibitors for interrogating disease

Gupta, Praveer, Reid, Robert C., Iyer, Abishek, Sweet, Matthew J. and Fairlie, David (2012). Towards isozyme-selective HDA inhibitors for interrogating disease. Current Topics in Medicinal Chemistry, 12 (14), 1479-1499. doi: 10.2174/156802612802652420

Towards isozyme-selective HDA inhibitors for interrogating disease

2012

Journal Article

The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer

Chen, Kai-En, Richards, Ayanthi A., Arrifin, Juliana K., Ross, Ian L., Sweet, Matthew J., Kellie, Stuart, Kobe, Bostjan and Martin, Jennifer L. (2012). The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer. Acta Crystallographica Section D: Biological Crystallography, 68 (6), 637-648. doi: 10.1107/S0907444912006592

The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer

2012

Journal Article

Copper redistribution in murine macrophages in response to Salmonella infection

Achard, Maud E. S., Stafford, Sian L., Bokil, Nilesh J., Chartres, Jy, Bernhardt, Paul V., Schembri, Mark A., Sweet, Matthew J. and McEwan, Alastair G. (2012). Copper redistribution in murine macrophages in response to Salmonella infection. Biochemical Journal, 444 (1), 51-57. doi: 10.1042/BJ20112180

Copper redistribution in murine macrophages in response to Salmonella infection

2012

Journal Article

Macrophage secretory products induce an inflammatory phenotype in hepatocytes

Melino, Michelle, Gadd, Victoria L., Walker, Gene V., Skoien, Richard, Barrie, Helen D., Jothimani, Dinesh, Horsfall, Leigh, Jones, Alun, Sweet, Matthew J., Thomas, Gethin P., Clouston, Andrew D., Jonsson, Julie R. and Powell, Elizabeth E. (2012). Macrophage secretory products induce an inflammatory phenotype in hepatocytes. World Journal of Gastroenterology, 18 (15), 1732-1744. doi: 10.3748/wjg.v18.i15.1732

Macrophage secretory products induce an inflammatory phenotype in hepatocytes

2012

Conference Publication

Functional significance of evolutionary divergence in Toll-like receptor-regulated gene expression in human versus mouse

Sweet, M. J., Schroder, K., Irvine, K. M., Taylor, M., Bokil, N. J., Broomfield, S., Schembri, M. A., Stacey, K. J. and Hume, D. A. (2012). Functional significance of evolutionary divergence in Toll-like receptor-regulated gene expression in human versus mouse. European Congress of Immunology, Glasgow, Scotland, 5-8 September 2012. Oxford, United Kingdom: Wiley-Blackwell. doi: 10.1111/imm.12002

Functional significance of evolutionary divergence in Toll-like receptor-regulated gene expression in human versus mouse

2012

Journal Article

HDACs and their inhibitors in immunology: teaching anticancer drugs new tricks

Fairlie, David P. and Sweet, Matthew J. (2012). HDACs and their inhibitors in immunology: teaching anticancer drugs new tricks. Immunology and Cell Biology, 90 (1), 3-5. doi: 10.1038/icb.2011.105

HDACs and their inhibitors in immunology: teaching anticancer drugs new tricks

2012

Journal Article

HDAC inhibitors: Modulating leukocyte differentiation, survival, proliferation and inflammation

Sweet, Matthew J., Shakespear, Melanie R., Kamal, Nabilah A. and Fairlie, David P. (2012). HDAC inhibitors: Modulating leukocyte differentiation, survival, proliferation and inflammation. Immunology and Cell Biology, 90 (1), 14-22. doi: 10.1038/icb.2011.88

HDAC inhibitors: Modulating leukocyte differentiation, survival, proliferation and inflammation

2011

Journal Article

Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophages

Bokil, Nilesh J., Totsika, Makrina, Carey, Alison J., Stacey, Katryn J., Hancock, Viktoria, Saunders, Bernadette M., Ravasi, Timothy, Ulett, Glenn C., Schembri, Mark A. and Sweet, Matthew J. (2011). Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophages. Immunobiology, 216 (11), 1164-1171. doi: 10.1016/j.imbio.2011.05.011

Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophages

2011

Journal Article

Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection

Valkov, Eugene, Stamp, Anna, DiMaio, Frank, Baker, David, Verstak, Brett, Roversi, Pietro, Kellie, Stuart, Sweet, Matthew J., Mansell, Ashley, Gay, Nicholas J., Martin, Jennifer L. and Kobe, Bostjan (2011). Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection. Proceedings of the National Academy of Sciences of the United States of America, 108 (36), 14879-14884. doi: 10.1073/pnas.1104780108

Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection

2011

Journal Article

Osteal tissue macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model

Alexander, Kylie A., Chang, Ming K., Maylin, Erin R., Kohler, Thomas, Meuller, Ralph, Wu, Andy C., van Rooijen, Nico, Sweet, Matthew J ., Hume, David A., Raggatt, Liza J. and Pettit, Allison R. (2011). Osteal tissue macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model. Journal of Bone And Mineral Research, 26 (7), 1517-1532. doi: 10.1002/jbmr.354

Osteal tissue macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model

2011

Journal Article

Histone deacetylases as regulators of inflammation and immunity

Shakespear, Melanie R., Halili, Maria A., Irvine, Katharine M., Fairlie, David P. and Sweet, Matthew J. (2011). Histone deacetylases as regulators of inflammation and immunity. Trends in Immunology, 32 (7), 335-343. doi: 10.1016/j.it.2011.04.001

Histone deacetylases as regulators of inflammation and immunity

2011

Journal Article

B cells do not take up bacterial DNA: An essential role for antigen in exposure of DNA to toll-like receptor-9

Roberts, Tara L., Turner, Marian L., Dunn, Jasmyn A., Lenert, Petar, Ross, Ian L., Sweet, Matthew J. and Stacey, Katryn J. (2011). B cells do not take up bacterial DNA: An essential role for antigen in exposure of DNA to toll-like receptor-9. Immunology and Cell Biology, 89 (4), 517-525. doi: 10.1038/icb.2010.112

B cells do not take up bacterial DNA: An essential role for antigen in exposure of DNA to toll-like receptor-9

2011

Journal Article

The immunostimulatory activity of phosphorothioate CpG oligonucleotides is affected by distal sequence changes

Roberts, Tara L., Dunn, Jasmyn A., Sweet, Matthew J., Hume, David A. and Stacey, Katryn J. (2011). The immunostimulatory activity of phosphorothioate CpG oligonucleotides is affected by distal sequence changes. Molecular Immunology, 48 (8), 1027-1034. doi: 10.1016/j.molimm.2011.01.011

The immunostimulatory activity of phosphorothioate CpG oligonucleotides is affected by distal sequence changes

2011

Journal Article

Macrophage activation and differentiation signals regulate Schlafen-4 gene expression: Evidence for Schlafen-4 as a modulator of myelopoiesis

Van Zuylen, Wendy J., Garceau, Valerie, Idris, Adi, Schroder, Kate, Irvine, Katharine M., Lattin, Jane E., Ovchinnikov, Dmitry A., Perkins, Andrew C., Cook, Andrew D., Hamilton, John A., Hertzog, Paul J., Stacey, Katryn J., Kellie, Stuart, Hume, David A. and Sweet, Matthew J. (2011). Macrophage activation and differentiation signals regulate Schlafen-4 gene expression: Evidence for Schlafen-4 as a modulator of myelopoiesis. PLoS One, 6 (1) e15723, e15723-1-e15723-13. doi: 10.1371/journal.pone.0015723

Macrophage activation and differentiation signals regulate Schlafen-4 gene expression: Evidence for Schlafen-4 as a modulator of myelopoiesis

2011

Journal Article

LPS-Induced Cytokine Production in Human Monocytes and Macrophages

Rosso, M., Heine, H., Meusch, U., Quandt, D., Klein, C., Sweet, M. J. and Hauschildt, S. (2011). LPS-Induced Cytokine Production in Human Monocytes and Macrophages. Critical Reviews in Immunology, 31 (5), 379-446. doi: 10.1615/CritRevImmunol.v31.i5.20

LPS-Induced Cytokine Production in Human Monocytes and Macrophages

2011

Journal Article

Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides

Cascales, Laura, Henriques, Sónia T., Kerr, Markus C., Huang, Yen-Hua, Sweet, Matthew J., Daly, Norelle L. and Craik, David J. (2011). Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides. Journal of Biological Chemistry, Epub ahead of print (42), 36932-36943. doi: 10.1074/jbc.M111.264424

Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides

2010

Journal Article

Inhibitors selective for HDAC6 in enzymes and cells

Gupta, Praveer K., Reid, Robert C., Liu, Ligong, Lucke, Andrew J., Broomfield, Steve A., Andrews, Melanie R., Sweet, Matthew J. and Fairlie, David P. (2010). Inhibitors selective for HDAC6 in enzymes and cells. Bioorganic & Medicinal Chemistry Letters, 20 (23), 7067-7070. doi: 10.1016/j.bmcl.2010.09.100

Inhibitors selective for HDAC6 in enzymes and cells

2010

Journal Article

Dead cells certainly do matter, particularly when they can speak from the grave

Sweet, Matthew J. (2010). Dead cells certainly do matter, particularly when they can speak from the grave. Journal of Leukocyte Biology, 88 (6), 1065-1066. doi: 10.1189/jlb.0810443

Dead cells certainly do matter, particularly when they can speak from the grave