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2012 Journal Article Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophagesSchroder, Kate, Irvine, Katharine M., Taylor, Martin S., Bokil, Nilesh J., Le Cao, Kim-Anh, Masterman, Kelly-Anne, Labzin, Larisa I., Semple, Colin A., Kapetanovic, Ronan, Fairbairn, Lynsey, Akalin, Altuna, Faulkner, Geoffrey J., Baillie, John Kenneth, Gongora, Milena, Daub, Carsten O., Kawaji, Hideya, McLachlan, Geoffrey J., Goldman, Nick, Grimmond, Sean M., Carninci, Piero, Suzuki, Harukazu, Hayashizaki, Yoshihide, Lenhard, Boris, Hume, David A. and Sweet, Matthew J. (2012). Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages. Proceedings of the National Academy of Sciences of the USA, 109 (16), E944-E953. doi: 10.1073/pnas.1110156109 |
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2012 Journal Article Macrophage secretory products induce an inflammatory phenotype in hepatocytesMelino, Michelle, Gadd, Victoria L., Walker, Gene V., Skoien, Richard, Barrie, Helen D., Jothimani, Dinesh, Horsfall, Leigh, Jones, Alun, Sweet, Matthew J., Thomas, Gethin P., Clouston, Andrew D., Jonsson, Julie R. and Powell, Elizabeth E. (2012). Macrophage secretory products induce an inflammatory phenotype in hepatocytes. World Journal of Gastroenterology, 18 (15), 1732-1744. doi: 10.3748/wjg.v18.i15.1732 |
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2012 Journal Article HDACs and their inhibitors in immunology: teaching anticancer drugs new tricksFairlie, David P. and Sweet, Matthew J. (2012). HDACs and their inhibitors in immunology: teaching anticancer drugs new tricks. Immunology and Cell Biology, 90 (1), 3-5. doi: 10.1038/icb.2011.105 |
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2012 Journal Article HDAC inhibitors: Modulating leukocyte differentiation, survival, proliferation and inflammationSweet, Matthew J., Shakespear, Melanie R., Kamal, Nabilah A. and Fairlie, David P. (2012). HDAC inhibitors: Modulating leukocyte differentiation, survival, proliferation and inflammation. Immunology and Cell Biology, 90 (1), 14-22. doi: 10.1038/icb.2011.88 |
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2012 Conference Publication Functional significance of evolutionary divergence in Toll-like receptor-regulated gene expression in human versus mouseSweet, M. J., Schroder, K., Irvine, K. M., Taylor, M., Bokil, N. J., Broomfield, S., Schembri, M. A., Stacey, K. J. and Hume, D. A. (2012). Functional significance of evolutionary divergence in Toll-like receptor-regulated gene expression in human versus mouse. European Congress of Immunology, Glasgow, Scotland, 5-8 September 2012. Oxford, United Kingdom: Wiley-Blackwell. doi: 10.1111/imm.12002 |
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2011 Journal Article Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophagesBokil, Nilesh J., Totsika, Makrina, Carey, Alison J., Stacey, Katryn J., Hancock, Viktoria, Saunders, Bernadette M., Ravasi, Timothy, Ulett, Glenn C., Schembri, Mark A. and Sweet, Matthew J. (2011). Intramacrophage survival of uropathogenic Escherichia coli: differences between diverse clinical isolates and between mouse and human macrophages. Immunobiology, 216 (11), 1164-1171. doi: 10.1016/j.imbio.2011.05.011 |
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2011 Journal Article Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protectionValkov, Eugene, Stamp, Anna, DiMaio, Frank, Baker, David, Verstak, Brett, Roversi, Pietro, Kellie, Stuart, Sweet, Matthew J., Mansell, Ashley, Gay, Nicholas J., Martin, Jennifer L. and Kobe, Bostjan (2011). Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection. Proceedings of the National Academy of Sciences of the United States of America, 108 (36), 14879-14884. doi: 10.1073/pnas.1104780108 |
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2011 Journal Article Osteal tissue macrophages promote in vivo intramembranous bone healing in a mouse tibial injury modelAlexander, Kylie A., Chang, Ming K., Maylin, Erin R., Kohler, Thomas, Meuller, Ralph, Wu, Andy C., van Rooijen, Nico, Sweet, Matthew J ., Hume, David A., Raggatt, Liza J. and Pettit, Allison R. (2011). Osteal tissue macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model. Journal of Bone And Mineral Research, 26 (7), 1517-1532. doi: 10.1002/jbmr.354 |
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2011 Journal Article Histone deacetylases as regulators of inflammation and immunityShakespear, Melanie R., Halili, Maria A., Irvine, Katharine M., Fairlie, David P. and Sweet, Matthew J. (2011). Histone deacetylases as regulators of inflammation and immunity. Trends in Immunology, 32 (7), 335-343. doi: 10.1016/j.it.2011.04.001 |
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2011 Journal Article B cells do not take up bacterial DNA: An essential role for antigen in exposure of DNA to toll-like receptor-9Roberts, Tara L., Turner, Marian L., Dunn, Jasmyn A., Lenert, Petar, Ross, Ian L., Sweet, Matthew J. and Stacey, Katryn J. (2011). B cells do not take up bacterial DNA: An essential role for antigen in exposure of DNA to toll-like receptor-9. Immunology and Cell Biology, 89 (4), 517-525. doi: 10.1038/icb.2010.112 |
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2011 Journal Article The immunostimulatory activity of phosphorothioate CpG oligonucleotides is affected by distal sequence changesRoberts, Tara L., Dunn, Jasmyn A., Sweet, Matthew J., Hume, David A. and Stacey, Katryn J. (2011). The immunostimulatory activity of phosphorothioate CpG oligonucleotides is affected by distal sequence changes. Molecular Immunology, 48 (8), 1027-1034. doi: 10.1016/j.molimm.2011.01.011 |
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2011 Journal Article LPS-Induced Cytokine Production in Human Monocytes and MacrophagesRosso, M., Heine, H., Meusch, U., Quandt, D., Klein, C., Sweet, M. J. and Hauschildt, S. (2011). LPS-Induced Cytokine Production in Human Monocytes and Macrophages. Critical Reviews in Immunology, 31 (5), 379-446. doi: 10.1615/CritRevImmunol.v31.i5.20 |
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2011 Journal Article Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptidesCascales, Laura, Henriques, Sónia T., Kerr, Markus C., Huang, Yen-Hua, Sweet, Matthew J., Daly, Norelle L. and Craik, David J. (2011). Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides. Journal of Biological Chemistry, Epub ahead of print (42), 36932-36943. doi: 10.1074/jbc.M111.264424 |
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2011 Journal Article Macrophage activation and differentiation signals regulate Schlafen-4 gene expression: Evidence for Schlafen-4 as a modulator of myelopoiesisVan Zuylen, Wendy J., Garceau, Valerie, Idris, Adi, Schroder, Kate, Irvine, Katharine M., Lattin, Jane E., Ovchinnikov, Dmitry A., Perkins, Andrew C., Cook, Andrew D., Hamilton, John A., Hertzog, Paul J., Stacey, Katryn J., Kellie, Stuart, Hume, David A. and Sweet, Matthew J. (2011). Macrophage activation and differentiation signals regulate Schlafen-4 gene expression: Evidence for Schlafen-4 as a modulator of myelopoiesis. PLoS One, 6 (1) e15723, e15723-1-e15723-13. doi: 10.1371/journal.pone.0015723 |
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2010 Journal Article Inhibitors selective for HDAC6 in enzymes and cellsGupta, Praveer K., Reid, Robert C., Liu, Ligong, Lucke, Andrew J., Broomfield, Steve A., Andrews, Melanie R., Sweet, Matthew J. and Fairlie, David P. (2010). Inhibitors selective for HDAC6 in enzymes and cells. Bioorganic & Medicinal Chemistry Letters, 20 (23), 7067-7070. doi: 10.1016/j.bmcl.2010.09.100 |
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2010 Journal Article Dead cells certainly do matter, particularly when they can speak from the graveSweet, Matthew J. (2010). Dead cells certainly do matter, particularly when they can speak from the grave. Journal of Leukocyte Biology, 88 (6), 1065-1066. doi: 10.1189/jlb.0810443 |
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2010 Journal Article Phosphoinositide 3-kinase δ regulates membrane fission of Golgi carriers for selective cytokine secretionLow, Pei Ching, Misaki, Ryo, Schroder, Kate, Stanley, Amanda C., Sweet, Matthew J., Teasdale, Rohan D., Vanhaesebroeck, Bart, Meunier, Frédéric A., Taguchi, Tomohiko and Stow, Jennifer L. (2010). Phosphoinositide 3-kinase δ regulates membrane fission of Golgi carriers for selective cytokine secretion. Journal of Cell Biology, 190 (6), 1053-1065. doi: 10.1083/jcb.201001028 |
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2010 Journal Article Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D-2 synthasesChrist, Angelika N., Labzin, Larisa, Bourne, Gregory T., Fukunishi, Hirotada, Weber, Jane E., Sweet, Matthew J., Smythe, Mark L. and Flanagan, Jack U. (2010). Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D-2 synthases. Journal of Medicinal Chemistry, 53 (15), 5536-5548. doi: 10.1021/jm100194a |
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2010 Journal Article Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPSHalili, Maria A., Andrews, Melanie R., Labzin, Larisa I., Schroder, Kate, Matthias, Gabriele, Cao, Chun, Lovelace, Erica, Reid, Robert C., Le, Giang T., Hume, David A., Irvine, Katharine M., Matthias, Patrick, Fairlie, David P. and Sweet, Matthew J. (2010). Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS. Journal of Leukocyte Biology, 87 (6), 1103-1114. doi: 10.1189/jlb.0509363 |
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2010 Journal Article A conserved distal segment of the mouse CSF-1 receptor promoter is required for maximal expression of a reporter gene in macrophages and osteoclasts of transgenic miceOvchinnikov, Dmitry A., DeBats, Claire E. E., Sester, David P., Sweet, Matthew J. and Hume, David A. (2010). A conserved distal segment of the mouse CSF-1 receptor promoter is required for maximal expression of a reporter gene in macrophages and osteoclasts of transgenic mice. Journal of Leukocyte Biology, 87 (5), 815-822. doi: 10.1189/jlb.0809557 |