Skip to menu Skip to content Skip to footer
Dr Liviu Bodea
Dr

Liviu Bodea

Email: 

Overview

Background

Dr. Liviu-Gabriel Bodea is a Reserach Fellow at the School of Medical Sciences, Faculty of Medicine. He is also affiliated with the Clem Jones Centre in Ageing Dementia Reserach, Queensland Brain Institute, and a former Mid-Career Fellow of Dementia Australia Research Foundation.

Liviu was awarded his Dr.rer.nat. (PhD) title from the University of Bonn, Germany (2014), working in the group of Prof. Harald Neumann, an expert in microglial physiology who identified for the first time a role for the microglial receptor TREM2 (JEM 2005). Liviu then relocated to Australia as the Peter Hilton Early Career Fellow in Ageing Dementia Research (2014-2019) to conduct work together with Prof. Jürgen Götz, a world-renowned leader in Alzheimer's disease reserach. In 2024, Liviu obtained independent NHMRC founding and moved his work in the laboratory of A/Prof Karin Borges at the School of Biomedical Sciences, where he gains deeper insights into proteostais-induces alterations of cellular metabolism.

Liviu is a brain immune cell biologist focusing on the functional crosstalk between microglia, the main resident immune cells of the brain parenchyma, and the surrounding cell types, both in health and disease. He has significant experience in generating and analysing both in vivo and in vitro models (from stable cell lines and primary cultures to novel genetically modified mice) in combination with various biochemical and molecular techniques, ranging from high-resolution microscopy to de novo proteome pathway analysis and generating novel mouse model through CRISPR gene editing.

Liviu has extensive experience in guiding both undergraduate and postgraduate students into the wonders of scientific research :)

Complete List of Published Work: PubMed Bibliography

Funding and Awards

2024-2027 NHMRC Ideas Grant #2030460 (sole CI, salary and research)

2022-2024 Dementia Australia Research Foundation Mid-Carrier Research Fellowship (salary and research)

2022 The University of Queensland Research Stimulus Fellowship (salary)

2019 Emergency Services Queensland Philanthropic Support (research)

2018-2021 NHMRC Project Grant #1147569 (CIB, salary and research)

2014-2019 Peter Hilton Early Career Research Fellowship in Ageing Dement (salary)

Research Impact, Leadership and Professional Activities

Dr. Bodea attracted >3400 citations (h-index 15 @Google Scholar), including 6 articles with >100 citations (Google Scholar) and 3 Highly Cited Publications (Web of Science). In 2021, Expertscape recognised Dr. Bodea as one of the top-rated researchers in the field of tauopathy, placing him in the top 0.8% of >142k published authors worldwide on tauopathies between 2012 and 2021. His work was cited in 18 patents (5 granted).

Dr. Bodea's work on the microglial TYROBP in late-onset AD (Cell 2013, co-first author, former Highly Cited Publication @Web of Science) represents a milestone in the field, with >1700 citations (Google Scholar). He also revealed the complement-induced neurodegeneration of dopaminergic neurons following peripheral immune stimulation (JNeurosci 2014, first author). More recently, he coordinated studies that centred on the effect of Tau protein (molecule relevant for Alzheimer's disease) on protein synthesis (EMBO J 2019 and Acta Neuropathologica Communications 2021), the use of artificial amino acids and de novo proteome analysis for the investigation of memory (eLife 2020) and microglial physiology (STARProtocols 2023), and the role of neuronal PTEN enzyme in synaptic engulfment by microglia (Acta Neuropathologica 2020). He published authoritative reviews in the Journal of Neurochemistry (2017), Nature Reviews Neurology (2018), Nature Reviews Neuroscience (2018), and Brain Research Bulletin (2021).

Dr. Bodea acts as a grant reviewer for MS Research Australia (since 2019), Alzheimer’s Australia Dementia Research Foundation (since 2016) and NHMRC (since 2021). He was the Lead Guest Editor for a Special Research Topic in Frontiers in Cellular Neuroscience (2023), is a member of the Reviewer Board for Frontiers in Cellular Neuroscience and was a member of the Reviewer Board for the International Journal of Environmental Research and Public Health, Mental Health section. He is an ad-hoc reviewer for various top-tier publications, ranging from Science to Trends in Cell Biology.

Dr. Bodea has mentored and supervised the daily activity of PhD students (2 completed, 1 current), Honours students (4 completed, all awarded First Class distinctions), 2 research assistants, and >10 undergraduate students. His PhD students successfully received various awards (e.g., the Alistair Rushworth Fellowship, Merk-QBI Best Student Publication Award, Best Oral Presentation Award). Both his completed PhD students continue with academic careers: Dr. Joey Benetatos, following a successful post-doctoral training in the Fraenkel Lab (MIT, USA), is currently pursuing his second post-doctoral position in the Prof. Loren Looger group (UCSD, USA), and Dr. Harrison T Evans is holding an Alzheimer's Association Postdoctoral Fellowship and is the Leon Levy Fellow in the Prof. Eric Klann lab (NYU, USA).

Availability

Dr Liviu Bodea is:
Available for supervision

Qualifications

  • Doctor of Philosophy of Natural Science, Rheinische Friedrich Wilhelms Universität Bonn

Works

Search Professor Liviu Bodea’s works on UQ eSpace

36 works between 2007 and 2024

1 - 20 of 36 works

2024

Journal Article

DREADD Microglia? Targeted Microglial Gi Activation in the Acute Phase can Reduce Seizure Severity, but is Detrimental in the Long Term

Bodea, Liviu-Gabriel and Borges, Karin (2024). DREADD Microglia? Targeted Microglial Gi Activation in the Acute Phase can Reduce Seizure Severity, but is Detrimental in the Long Term. Epilepsy Currents. doi: 10.1177/15357597241279761

DREADD Microglia? Targeted Microglial Gi Activation in the Acute Phase can Reduce Seizure Severity, but is Detrimental in the Long Term

2024

Journal Article

LINE-1 retrotransposons contribute to mouse PV interneuron development

Bodea, Gabriela O., Botto, Juan M., Ferreiro, Maria E., Sanchez-Luque, Francisco J., de los Rios Barreda, Jose, Rasmussen, Jay, Rahman, Muhammed A., Fenlon, Laura R., Jansz, Natasha, Gubert, Carolina, Gerdes, Patricia, Bodea, Liviu-Gabriel, Ajjikuttira, Prabha, Da Costa Guevara, Darwin J., Cumner, Linda, Bell, Charles C., Kozulin, Peter, Billon, Victor, Morell, Santiago, Kempen, Marie-Jeanne H. C., Love, Chloe J., Saha, Karabi, Palmer, Lucy M., Ewing, Adam D., Jhaveri, Dhanisha J., Richardson, Sandra R., Hannan, Anthony J. and Faulkner, Geoffrey J. (2024). LINE-1 retrotransposons contribute to mouse PV interneuron development. Nature Neuroscience, 27 (7), 1-34. doi: 10.1038/s41593-024-01650-2

LINE-1 retrotransposons contribute to mouse PV interneuron development

2024

Journal Article

Scanning ultrasound-mediated memory and functional improvements do not require amyloid-β reduction

Leinenga, Gerhard, To, Xuan Vinh, Bodea, Liviu-Gabriel, Yousef, Jumana, Richter-Stretton, Gina, Palliyaguru, Tishila, Chicoteau, Antony, Dagley, Laura, Nasrallah, Fatima and Götz, Jürgen (2024). Scanning ultrasound-mediated memory and functional improvements do not require amyloid-β reduction. Molecular Psychiatry, 29 (8), 1-16. doi: 10.1038/s41380-024-02509-5

Scanning ultrasound-mediated memory and functional improvements do not require amyloid-β reduction

2024

Journal Article

Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic lipid and carbohydrate metabolism

Keshvari, Sahar, Masson, Jesse J.R., Ferrari-Cestari, Michelle, Bodea, Liviu-Gabriel, Nooru-Mohamed, Fathima, Tse, Brian W.C., Sokolowski, Kamil A., Batoon, Lena, Patkar, Omkar L., Sullivan, Mitchell A., Ebersbach, Hilmar, Stutz, Cian, Parton, Robert G., Summers, Kim M., Pettit, Allison R., Hume, David A. and Irvine, Katharine M. (2024). Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic lipid and carbohydrate metabolism. American Journal of Physiology-Endocrinology and Metabolism, 326 (2), E149-E165. doi: 10.1152/ajpendo.00347.2023

Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic lipid and carbohydrate metabolism

2023

Journal Article

Three methods for examining the de novo proteome of microglia using BONCAT bioorthogonal labeling and FUNCAT click chemistry

Carlisle, Alison Keolani, Götz, Jürgen and Bodea, Liviu-Gabriel (2023). Three methods for examining the de novo proteome of microglia using BONCAT bioorthogonal labeling and FUNCAT click chemistry. STAR Protocols, 4 (3) 102418, 102418. doi: 10.1016/j.xpro.2023.102418

Three methods for examining the de novo proteome of microglia using BONCAT bioorthogonal labeling and FUNCAT click chemistry

2023

Other Outputs

Scanning ultrasound-mediated memory and functional improvements do not require amyloid-β reduction

Leinenga, Gerhard, To, Xuan Vinh, Bodea, Liviu-Gabriel, Youse, Jumana, Richter-Stretton, Gina, Palliyaguru, Tishila, Chicoteau, Antony, Dagley, Laura, Nasrallah, Fatima and Götz, Jürgen (2023). Scanning ultrasound-mediated memory and functional improvements do not require amyloid-β reduction.

Scanning ultrasound-mediated memory and functional improvements do not require amyloid-β reduction

2023

Journal Article

Editorial: the neuron-glia crosstalk and beyond

Middeldorp, Jinte, Min, Rogier, Benetatos, Joseph and Bodea, Liviu-Gabriel (2023). Editorial: the neuron-glia crosstalk and beyond. Frontiers in Cellular Neuroscience, 17 1159597, 1-3. doi: 10.3389/fncel.2023.1159597

Editorial: the neuron-glia crosstalk and beyond

2022

Journal Article

Isolation and culture of pure adult mouse microglia and astrocytes for in vitro characterization and analyses

Milner, Mark T., Lawrence, Grace M. E. P., Holley, Caroline L., Bodea, Liviu-Gabriel, Götz, Jürgen, Burgener, Sabrina S. and Schroder, Kate (2022). Isolation and culture of pure adult mouse microglia and astrocytes for in vitro characterization and analyses. STAR Protocols, 3 (2) 101295, 1-16. doi: 10.1016/j.xpro.2022.101295

Isolation and culture of pure adult mouse microglia and astrocytes for in vitro characterization and analyses

2022

Journal Article

Transcriptional signature in microglia isolated from an Alzheimer's disease mouse model treated with scanning ultrasound

Leinenga, Gerhard, Bodea, Liviu‐Gabriel, Schröder, Jan, Sun, Giuzhi, Zhou, Yichen, Song, Jae, Grubman, Alexandra, Polo, Jose M. and Götz, Jürgen (2022). Transcriptional signature in microglia isolated from an Alzheimer's disease mouse model treated with scanning ultrasound. Bioengineering & Translational Medicine, 8 (1) e10329, e10329. doi: 10.1002/btm2.10329

Transcriptional signature in microglia isolated from an Alzheimer's disease mouse model treated with scanning ultrasound

2022

Journal Article

LINE-1 retrotransposon activation intrinsic to interneuron development

Bodea, Gabriela O., Ferreiro, Maria E., Sanchez-Luque, Francisco J., Botto, Juan M., Rasmussen, Jay, Rahman, Muhammed A., Fenlon, Laura R., Gubert, Carolina, Gerdes, Patricia, Bodea, Liviu-Gabriel, Ajjikuttira, Prabha, Kozulin, Peter, Billon, Victor, Morell, Santiago, Kempen, Marie-Jeanne H.C., Love, Chloe J., Palmer, Lucy M., Ewing, Adam D., Jhaveri, Dhanisha J., Richardson, Sandra R., Hannan, Anthony J. and Faulkner, Geoffrey J. (2022). LINE-1 retrotransposon activation intrinsic to interneuron development.

LINE-1 retrotransposon activation intrinsic to interneuron development

2021

Journal Article

An early proinflammatory transcriptional response to tau pathology is age‐specific and foreshadows reduced tau burden

Rasmussen, Jay, Ewing, Adam D., Bodea, Liviu‐Gabriel, Bodea, Gabriela O., Gearing, Marla and Faulkner, Geoffrey J. (2021). An early proinflammatory transcriptional response to tau pathology is age‐specific and foreshadows reduced tau burden. Brain Pathology, 32 (3) e13018, e13018. doi: 10.1111/bpa.13018

An early proinflammatory transcriptional response to tau pathology is age‐specific and foreshadows reduced tau burden

2021

Journal Article

Altered ribosomal function and protein synthesis caused by tau

Evans, Harrison Tudor, Taylor, Deonne, Kneynsberg, Andrew, Bodea, Liviu-Gabriel and Götz, Jürgen (2021). Altered ribosomal function and protein synthesis caused by tau. Acta Neuropathologica Communications, 9 (1) 110, 110. doi: 10.1186/s40478-021-01208-4

Altered ribosomal function and protein synthesis caused by tau

2021

Journal Article

De novo proteomic methods for examining the molecular mechanisms underpinning long-term memory

Evans, Harrison Tudor, Blackmore, Daniel, Goetz, Juergen and Bodea, Liviu-Gabriel (2021). De novo proteomic methods for examining the molecular mechanisms underpinning long-term memory. Brain Research Bulletin, 169, 94-103. doi: 10.1016/j.brainresbull.2020.12.015

De novo proteomic methods for examining the molecular mechanisms underpinning long-term memory

2021

Journal Article

Tau antibody isotype induces differential effects following passive immunisation of tau transgenic mice

Bajracharya, Rinie, Brici, David, Bodea, Liviu-Gabriel, Janowicz, Phillip W., Götz, Jürgen and Nisbet, Rebecca M. (2021). Tau antibody isotype induces differential effects following passive immunisation of tau transgenic mice. Acta Neuropathologica Communications, 9 (1) 42, 1-13. doi: 10.1186/s40478-021-01147-0

Tau antibody isotype induces differential effects following passive immunisation of tau transgenic mice

2020

Journal Article

Delivery of antibodies into the brain using focused scanning ultrasound

Leinenga, Gerhard, Bodea, Liviu-Gabriel, Koh, Wee Kiat, Nisbet, Rebecca M. and Götz, Jürgen (2020). Delivery of antibodies into the brain using focused scanning ultrasound. Journal of Visualized Experiments, 2020 (161) e61372, 1-13. doi: 10.3791/61372

Delivery of antibodies into the brain using focused scanning ultrasound

2020

Journal Article

PTEN activation contributes to neuronal and synaptic engulfment by microglia in tauopathy

Benetatos, Joseph, Bennett, Rachel E., Evans, Harrison T., Ellis, Sevannah A., Hyman, Bradley T., Bodea, Liviu-Gabriel and Götz, Jürgen (2020). PTEN activation contributes to neuronal and synaptic engulfment by microglia in tauopathy. Acta Neuropathologica, 140 (1), 7-24. doi: 10.1007/s00401-020-02151-9

PTEN activation contributes to neuronal and synaptic engulfment by microglia in tauopathy

2020

Journal Article

Cell-specific non-canonical amino acid labelling identifies changes in the de novo proteome during memory formation

Evans, Harrison Tudor, Bodea, Liviu-Gabriel and Götz, Jürgen (2020). Cell-specific non-canonical amino acid labelling identifies changes in the de novo proteome during memory formation. eLife, 9 e52990, e52990. doi: 10.7554/elife.52990

Cell-specific non-canonical amino acid labelling identifies changes in the de novo proteome during memory formation

2019

Journal Article

Decreased synthesis of ribosomal proteins in tauopathy revealed by non‐canonical amino acid labelling

Evans, Harrison Tudor, Benetatos, Joseph, van Roijen, Marloes, Bodea, Liviu‐Gabriel and Götz, Jürgen (2019). Decreased synthesis of ribosomal proteins in tauopathy revealed by non‐canonical amino acid labelling. The EMBO Journal, 38 (13) e101174, e101174. doi: 10.15252/embj.2018101174

Decreased synthesis of ribosomal proteins in tauopathy revealed by non‐canonical amino acid labelling

2019

Journal Article

TREM2 triggers microglial density and age-related neuronal loss

Linnartz-Gerlach, Bettina, Bodea, Liviu-Gabriel, Klaus, Christine, Ginolhac, Aurélien, Halder, Rashi, Sinkkonen, Lasse, Walter, Jochen, Colonna, Marco and Neumann, Harald (2019). TREM2 triggers microglial density and age-related neuronal loss. GLIA, 67 (3) glia.23563, 539-550. doi: 10.1002/glia.23563

TREM2 triggers microglial density and age-related neuronal loss

2018

Journal Article

Rodent models for Alzheimer disease

Götz, Jürgen, Bodea, Liviu-Gabriel and Goedert, Michel (2018). Rodent models for Alzheimer disease. Nature Reviews Neuroscience, 19 (10), 583-598. doi: 10.1038/s41583-018-0054-8

Rodent models for Alzheimer disease

Funding

Current funding

  • 2024 - 2027
    Targetting the microglial integrated stress response to fight off Alzheimer's disease
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2022 - 2024
    Rejuvenating microglia to alleviate Alzheimer's disease
    Dementia Australia Research Foundation
    Open grant
  • 2018 - 2021
    Role of the microglial adaptor molecule TYROBP in Alzheimer's disease pathology
    NHMRC Project Grant
    Open grant

Supervision

Availability

Dr Liviu Bodea is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    The impact of peripheral inflammation on neurodegeneration

    Principal Advisor

    Other advisors: Professor Jürgen Götz

Completed supervision

Media

Enquiries

For media enquiries about Dr Liviu Bodea's areas of expertise, story ideas and help finding experts, contact our Media team:

communications@uq.edu.au