Dr Karishma Mody
Dr

Karishma Mody

Email: 
Phone: 
+61 7 334 62318

Background

I am an agricultural biotechnologist specialising in applications of nanotechnology to improve animal health. My PhD was a part of a multi-disciplinary research project facilitated by the Queensland Government Research Partnerships at QAAFI. This research, for the first time, established silica nanomaterials as carriers and self-adjuvants for vaccine development and delivery against Bovine Viral Diarrhoea Virus. As a Research Fellow at QAAFI, I am leading the research using RNA interference technology and material science to develop sustainable solutions for real-world problems like sheep blowfly and lice-infestation.

We are always seeking for motivated Honours and PhD applicants, please get in touch, if that sounds like you!

Availability

Dr Karishma Mody is:
Available for supervision

Qualifications

  • Doctor of Philosophy, The University of Queensland

Search Professor Karishma Mody’s works on UQ eSpace

17 works between 2012 and 2024
All (17) Journal Article (15) Conference Publication (1) Other Outputs (1)

1 - 17 of 17 works

2024

Journal Article

Chromosome-scale genome assembly of the sheep-biting louse Bovicola ovis using nanopore sequencing data and Pore-C analysis

Ong, Chian Teng, Mody, Karishma T., Cavallaro, Antonino S., Yan, Yakun, Nguyen, Loan T., Shao, Renfu, Mitter, Neena, Mahony, Timothy J. and Ross, Elizabeth M. (2024). Chromosome-scale genome assembly of the sheep-biting louse Bovicola ovis using nanopore sequencing data and Pore-C analysis. International Journal of Molecular Sciences, 25 (14) 7824, 1-15. doi: 10.3390/ijms25147824

Chromosome-scale genome assembly of the sheep-biting louse Bovicola ovis using nanopore sequencing data and Pore-C analysis

2024

Journal Article

The use of cell and larval assays to identify target genes for <scp>RNA</scp> interference‐meditated control of the Australian sheep blowfly (<scp><i>Lucilia cuprina</i></scp>)

Yang, Yunjia, Zhang, Bing, Yong, Jiaxi, James, Peter, Xu, Zhi Ping, Mitter, Neena, Mahony, Timothy J and Mody, Karishma T (2024). The use of cell and larval assays to identify target genes for RNA interference‐meditated control of the Australian sheep blowfly (Lucilia cuprina). Pest Management Science, 80 (9), 4686-4698. doi: 10.1002/ps.8190

The use of cell and larval assays to identify target genes for <scp>RNA</scp> interference‐meditated control of the Australian sheep blowfly (<scp><i>Lucilia cuprina</i></scp>)

2022

Journal Article

RNAi-Based Biocontrol of Pests to Improve the Productivity and Welfare of Livestock Production

Menezes, Pia S., Yan, Yakun, Yang, Yunjia, Mitter, Neena, Mahony, Timothy J. and Mody, Karishma T. (2022). RNAi-Based Biocontrol of Pests to Improve the Productivity and Welfare of Livestock Production. Applied Biosciences, 1 (3), 229-243. doi: 10.3390/applbiosci1030015

RNAi-Based Biocontrol of Pests to Improve the Productivity and Welfare of Livestock Production

2021

Journal Article

Synergistic effect of two nanotechnologies enhances the protective capacity of the Theileria parva Sporozoite p67C antigen in cattle

Lacasta, Anna, Mody, Karishma T, De Goeyse, Ine, Yu, Chengzhong, Zhang, Jun, Nyagwange, James, Mwalimu, Stephen, Awino, Elias, Saya, Rosemary, Njoroge, Thomas, Muriuki, Robert, Ndiwa, Nicholas, Poole, Elisabeth Jane, Zhang, Bing, Cavallaro, Antonino, Mahony, Timothy J, Steinaa, Lucilla, Mitter, Neena and Nene, Vishvanath (2021). Synergistic effect of two nanotechnologies enhances the protective capacity of the Theileria parva Sporozoite p67C antigen in cattle. Journal of Immunology, 206 (4), 686-699. doi: 10.4049/jimmunol.2000442

Synergistic effect of two nanotechnologies enhances the protective capacity of the Theileria parva Sporozoite p67C antigen in cattle

2021

Journal Article

Characterization of the biodistribution of a silica vesicle Nanovaccine carrying a Rhipicephalus (Boophilus) microplus protective antigen with in vivo live animal imaging

Mody, Karishma T., Zhang, Bing, Li, Xun, Fletcher, Nicholas L., Akhter, Dewan T., Jarrett, Sandy, Zhang, Jun, Yu, Chengzhong, Thurecht, Kristofer J., Mahony, Timothy J and Mitter, Neena (2021). Characterization of the biodistribution of a silica vesicle Nanovaccine carrying a Rhipicephalus (Boophilus) microplus protective antigen with in vivo live animal imaging. Frontiers in Bioengineering and Biotechnology, 8 606652, 1-11. doi: 10.3389/fbioe.2020.606652

Characterization of the biodistribution of a silica vesicle Nanovaccine carrying a Rhipicephalus (Boophilus) microplus protective antigen with in vivo live animal imaging

2020

Conference Publication

Topical RNAi for Sustainable Animal Health

Mody, Karishma T., Zhang, Bing, Li, Xun, Jain, Ritesh, Li, Peng, James, Peter, Mahony, Timothy J., Xu, Zhiping and Mitter, Neena (2020). Topical RNAi for Sustainable Animal Health. TropAg 2019, Brisbane, QLD Australia, 11-13 November 2019. Basel, Switzerland: MDPI. doi: 10.3390/proceedings2019036170

Topical RNAi for Sustainable Animal Health

2018

Journal Article

Nanotechnology for plant disease management

Worrall, Elizabeth, Hamid, Aflaq, Mody, Karishma, Mitter, Neena and Pappu, Hanu (2018). Nanotechnology for plant disease management. Agronomy, 8 (12) 256, 285. doi: 10.3390/agronomy8120285

Nanotechnology for plant disease management

2016

Journal Article

Nanoparticle-based delivery of Anaplasma marginale membrane proteins, VirB9-1 and VirB10 produced in the Pichia pastoris expression system

Zhang, Bing, Cavallaro, Antonio S., Mody, Karishma T., Zhang, Jun, Deringer, James R., Brown, Wendy C., Mahony, Timothy J., Yu, Chengzhong and Mitter, Neena (2016). Nanoparticle-based delivery of Anaplasma marginale membrane proteins, VirB9-1 and VirB10 produced in the Pichia pastoris expression system. Nanomaterials, 6 (11) 201, 201. doi: 10.3390/nano6110201

Nanoparticle-based delivery of Anaplasma marginale membrane proteins, VirB9-1 and VirB10 produced in the Pichia pastoris expression system

2016

Journal Article

Correction: Silica Vesicle Nanovaccine Formulations Stimulate Long-Term Immune Responses to the Bovine Viral Diarrhoea Virus E2 Protein (vol 10, e0143507, 2015)

Mody, Karishma T., Mahony, Donna, Cavallaro, Antonino S., Zhang, Jun, Zhang, Bing, Mahony, Timothy J., Yu, Chengzhong and Mitter, Neena (2016). Correction: Silica Vesicle Nanovaccine Formulations Stimulate Long-Term Immune Responses to the Bovine Viral Diarrhoea Virus E2 Protein (vol 10, e0143507, 2015). Plos One, 11 (1) e0146631, 1-1. doi: 10.1371/journal.pone.0146631

Correction: Silica Vesicle Nanovaccine Formulations Stimulate Long-Term Immune Responses to the Bovine Viral Diarrhoea Virus E2 Protein (vol 10, e0143507, 2015)

2015

Journal Article

Silica vesicle nanovaccine formulations stimulate long-term immune responses to the bovine viral diarrhoea virus e2 protein

Mody, Karishma T., Mahony, Donna, Cavallaro, Antonino S., Zhang, Jun, Zhang, Bing, Mahony, Timothy J., Yu, Chengzhong and Mitter, Neena (2015). Silica vesicle nanovaccine formulations stimulate long-term immune responses to the bovine viral diarrhoea virus e2 protein. PLoS One, 10 (12) e0143507, 1-16. doi: 10.1371/journal.pone.0143507

Silica vesicle nanovaccine formulations stimulate long-term immune responses to the bovine viral diarrhoea virus e2 protein

2015

Journal Article

Immunisation of Sheep with Bovine Viral Diarrhoea Virus, E2 Protein Using a Freeze-Dried Hollow Silica Mesoporous Nanoparticle Formulation

Mahony, Donna, Mody, Karishma T., Cavallaro, Antonino S., Hu, Qiuhong, Mahony, Timothy J., Qiao, Shizhang and Mitter, Neena (2015). Immunisation of Sheep with Bovine Viral Diarrhoea Virus, E2 Protein Using a Freeze-Dried Hollow Silica Mesoporous Nanoparticle Formulation. Plos One, 10 (11) e0141870, e0141870. doi: 10.1371/journal.pone.0141870

Immunisation of Sheep with Bovine Viral Diarrhoea Virus, E2 Protein Using a Freeze-Dried Hollow Silica Mesoporous Nanoparticle Formulation

2015

Other Outputs

Development of nanoparticle based vaccine delivery systems

Mody, Karishma (2015). Development of nanoparticle based vaccine delivery systems. PhD Thesis, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland. doi: 10.14264/uql.2015.934

Development of nanoparticle based vaccine delivery systems

2014

Journal Article

Silica vesicles as nanocarriers and adjuvants for generating both antibody and T-cell mediated immune resposes to Bovine Viral Diarrhoea Virus E2 protein

Mody, Karishma T., Mahony, Donna, Zhang, Jun, Cavallaro, Antonino S., Zhang, Bing, Popat, Amirali, Mahony, Timothy J., Yu, Chengzhong and Mitter, Neena (2014). Silica vesicles as nanocarriers and adjuvants for generating both antibody and T-cell mediated immune resposes to Bovine Viral Diarrhoea Virus E2 protein. Biomaterials, 35 (37), 9972-9983. doi: 10.1016/j.biomaterials.2014.08.044

Silica vesicles as nanocarriers and adjuvants for generating both antibody and T-cell mediated immune resposes to Bovine Viral Diarrhoea Virus E2 protein

2014

Journal Article

Freeze-drying of ovalbumin loaded mesoporous silica nanoparticle vaccine formulation increases antigen stability under ambient conditions

Mody, Karishma T., Mahony, Donna, Cavallaro, Antonino S., Stahr, Frances, Qiao, Shi Zhang, Mahony, Timothy J. and Mitter, Neena (2014). Freeze-drying of ovalbumin loaded mesoporous silica nanoparticle vaccine formulation increases antigen stability under ambient conditions. International Journal of Pharmaceutics, 465 (1-2), 325-332. doi: 10.1016/j.ijpharm.2014.01.037

Freeze-drying of ovalbumin loaded mesoporous silica nanoparticle vaccine formulation increases antigen stability under ambient conditions

2014

Journal Article

In vivo delivery of bovine viral diahorrea virus, E2 protein using hollow mesoporous silica nanoparticles

Mahony, D., Cavallaro, A. S., Mody, K. T., Xiong, L., Mahony, T. J., Qiao, S. Z. and Mitter, Neena (2014). In vivo delivery of bovine viral diahorrea virus, E2 protein using hollow mesoporous silica nanoparticles. Nanoscale, 6 (12), 6617-6626. doi: 10.1039/C4NR01202J

In vivo delivery of bovine viral diahorrea virus, E2 protein using hollow mesoporous silica nanoparticles

2013

Journal Article

Mesoporous silica nanoparticles as antigen carriers and adjuvants for vaccine delivery

Mody, Karishma T., Popat, Amirali, Mahony, Donna, Cavallaro, Antonino S., Yu, Chengzhong and Mitter, Neena (2013). Mesoporous silica nanoparticles as antigen carriers and adjuvants for vaccine delivery. Nanoscale, 5 (12), 5167-5179. doi: 10.1039/c3nr00357d

Mesoporous silica nanoparticles as antigen carriers and adjuvants for vaccine delivery

2012

Journal Article

Freeze-drying of protein-loaded nanoparticles for vaccine delivery

Mody, Karishma, Mahony, Donna, Mahony, Tim and Mitter, Neena (2012). Freeze-drying of protein-loaded nanoparticles for vaccine delivery. Drug Delivery Letters, 2 (2), 83-91. doi: 10.2174/2210304x11202020083

Freeze-drying of protein-loaded nanoparticles for vaccine delivery

Past funding

  • 2020 - 2023
    BioClay: Safe guarding Queensland through reduced on-farm pesticide usage.
    Advance Queensland Industry Research Fellowships
    Open grant

Availability

Dr Karishma Mody is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

  • Topical RNAi for Sustainable Animal Health

    The aim of the project is to develop a sustainable solution using clay particles to deliver RNA to protect Queensland’s sheep from flystrike and lice infestation. Current control measures mainly rely on vaccination or chemical control, causing issues of residue and toxicity. Both of these pathogens have developed resistance to nearly all control chemicals used in the past. This project will deliver a clean-green formulation to counter chemical resistance, improve animal welfare, reduce residues in products, allowing better responses to market demands.

  • Applications of RNAi for developing sustainable solution for Fire-ants

    The project: Insect parasites cause significant damage to livestock and are primarily responsible for significant economic losses. Conventional pesticides have issues of resistance and toxicity, and there is increasing market requirement and price premiums for low-chemical and welfare-friendly production systems. We aim to explore our RNAi delivery platform to protect animals from insect parasites that cause damage. This project will result in real-world outcomes, by translating and expanding our current biotechnologies to an industry-ready tool for animal protection.

    The student: will learn valuable techniques and strong skills in experimental design, molecular biology (cloning, PCR, qRTPCR, sequencing, RNA/DNA extractions), bioinformatics, material science and the application of RNAi in animal protection. The student will work closely with Dr Karishma Mody and other members of the Mitter laboratory at UQ.

    Location: UQ Mitter Laboratory, QAAFI, Queensland Bioscience Precinct, UQ St Lucia campus.

    Supervisors: Dr Karishma Mody (k.mody@uq.edu.au) & Prof Neena Mitter (n.mitter@uq.edu.au)

    Note: We work on a range of different insect targets like fire-ants and sheep/cattle parasites with industry partners. If this projects interest you, please send me an email. We can discuss further details.

Supervision history

Current supervision

Enquiries

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communications@uq.edu.au