
Overview
Background
Anson received his PhD in 2018 from the University of Melbourne and continued his study on the molecular basis of membrane trafficking and protein sorting in the Golgi with Professor Paul Gleeson. In 2020, Dr Tan joined the Queensland Brain Institute at the University of Queensland, where he is currently a Postdoctoral Research Fellow at the Clem Jones Centre for Ageing Dementia Research. His research at the Anggono laboratory aims to understand the molecular mechanisms of membrane trafficking in neurons, processes that are essential for synaptic transmission, plasticity, learning and memory, and how their dysregulation led to neurodegenerative diseases and neuropsychiatric disorders. Dr Tan was recently awarded the UQ Postdoctoral Researcher Retention Fellowship (University of Queensland, 2022).
Availability
- Dr Anson Tan is:
- Available for supervision
Qualifications
- Doctor of Philosophy of Protein Trafficking, University of Melbourne
Research interests
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Neuronal Trafficking
The molecular basis and regulation of membrane trafficking between intracellular compartments are essential for neuronal communications, learning and memory.
Works
Search Professor Anson Tan’s works on UQ eSpace
2023
Journal Article
Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
Tan, Jing Zhi Anson, Jang, Se Eun, Batallas-Borja, Ana, Bhembre, Nishita, Chandra, Mintu, Zhang, Lingrui, Guo, Huimin, Ringuet, Mitchell T., Widagdo, Jocelyn, Collins, Brett M. and Anggono, Victor (2023). Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis. Cell Reports, 42 (12) 113460, 1-20. doi: 10.1016/j.celrep.2023.113460
2023
Journal Article
Structural basis for enhanced cytoplasmic aggregation of familial ALS-associated SFPQ mutants
Widagdo, J., Udagedara, S., Bhembre, N., Tan, J. Z. A., Neureiter, L., Huang, J., Anggono, V. and Lee, M. (2023). Structural basis for enhanced cytoplasmic aggregation of familial ALS-associated SFPQ mutants. Acta Crystallographica Section A Foundations and Advances, 79 (a2), C7-C7. doi: 10.1107/s2053273323096018
2022
Journal Article
Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates in primary neurons
Widagdo, Jocelyn, Udagedara, Saumya, Bhembre, Nishita, Tan, Jing Zhi Anson, Neureiter, Lara, Huang, Jie, Anggono, Victor and Lee, Mihwa (2022). Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates in primary neurons. Open Biology, 12 (9) 220187, 1-12. doi: 10.1098/rsob.220187
2021
Journal Article
Regulation of NMDA receptor trafficking and gating by activity-dependent CaMKIIα phosphorylation of the GluN2A subunit
Yong, Xuan Ling Hilary, Zhang, Lingrui, Yang, Liming, Chen, Xiumin, Tan, Jing Zhi Anson, Yu, Xiaojun, Chandra, Mintu, Livingstone, Emma, Widagdo, Jocelyn, Vieira, Marta M., Roche, Katherine W., Lynch, Joseph W., Keramidas, Angelo, Collins, Brett M. and Anggono, Victor (2021). Regulation of NMDA receptor trafficking and gating by activity-dependent CaMKIIα phosphorylation of the GluN2A subunit. Cell Reports, 36 (1) 109338, 1-21. doi: 10.1016/j.celrep.2021.109338
2020
Journal Article
Distinct anterograde trafficking pathways of BACE1 and amyloid precursor protein from the TGN and the regulation of amyloid-beta production
Tan, Jing Zhi A., Fourriere, Lou, Wang, Jingqi, Perez, Franck, Boncompain, Gaelle and Gleeson, Paul A. (2020). Distinct anterograde trafficking pathways of BACE1 and amyloid precursor protein from the TGN and the regulation of amyloid-beta production. Molecular Biology of the Cell, 31 (1), 27-44. doi: 10.1091/mbc.E19-09-0487
2019
Journal Article
Cargo Sorting at the trans-Golgi Network for Shunting into Specific Transport Routes: Role of Arf Small G Proteins and Adaptor Complexes
Tan, Jing Zhi Anson and Gleeson, Paul Anthony (2019). Cargo Sorting at the trans-Golgi Network for Shunting into Specific Transport Routes: Role of Arf Small G Proteins and Adaptor Complexes. Cells, 8 (6) 531, 531. doi: 10.3390/cells8060531
2019
Journal Article
The role of membrane trafficking in the processing of amyloid precursor protein and production of amyloid peptides in Alzheimer's disease
Tan, Jing Zhi A. and Gleeson, Paul A. (2019). The role of membrane trafficking in the processing of amyloid precursor protein and production of amyloid peptides in Alzheimer's disease. Biochimica Et Biophysica Acta-Biomembranes, 1861 (4), 697-712. doi: 10.1016/j.bbamem.2018.11.013
2019
Journal Article
The trans-Golgi network is a major site for alpha-secretase processing of amyloid precursor protein in primary neurons
Tan, Jing Zhi A. and Gleeson, Paul A. (2019). The trans-Golgi network is a major site for alpha-secretase processing of amyloid precursor protein in primary neurons. Journal of Biological Chemistry, 294 (5), 1618-1631. doi: 10.1074/jbc.RA118.005222
2017
Journal Article
Amyloid precursor protein traffics from the Golgi directly to early endosomes in an Arl5b-and AP4-dependent pathway
Toh, Wei Hong, Tan, Jing Zhi A., Zulkefli, Khalisah L., Houghton, Fiona J. and Gleeson, Paul A. (2017). Amyloid precursor protein traffics from the Golgi directly to early endosomes in an Arl5b-and AP4-dependent pathway. Traffic, 18 (3), 159-175. doi: 10.1111/tra.12465
Supervision
Availability
- Dr Anson Tan is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Regulation of synapse to nucleus signalling during synaptic plasticity
Associate Advisor
Other advisors: Dr Jocelyn Widagdo, Associate Professor Victor Anggono
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Doctor Philosophy
Epigenetic Regulation of Learning and Memory
Associate Advisor
Other advisors: Associate Professor Victor Anggono, Dr Jocelyn Widagdo
Completed supervision
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2024
Doctor Philosophy
Defining the mechanisms of Copine-6 lipid-binding properties in regulating the activity-dependent trafficking of glutamate receptors
Associate Advisor
Other advisors: Associate Professor Victor Anggono
Media
Enquiries
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